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ARVO Annual Meeting Abstract July 2019

Comparing the efficacy of bevacizumab to ranibizumab in patients with diabetic macular edema: the BRDME study

Maartje J.C. Vader; Ann-Sofie M.E. Schauwvlieghe; Frank D Verbraak; Greetje Dijkman; Johanna M.M. Hooymans; Leonie I. Los; Aeilko H. Zwinderman; Tunde Peto; Carel B. Hoyng; Redmer van Leeuwen; Johannes R. Vingerling; Annette C. Moll; Janneke J.C. van Lith-Verhoeven; Marcel G.W. Dijkgraaf; Reinier O. Schlingemann

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3648. doi:

ARVO Annual Meeting Abstract July 2018

Sodium iodate-induced retinal degeneration in small animal models for Age-related Macular degeneration

Céline Koster; Anneloor ten Asbroek; Jacoline ten Brink; Reinier O Schlingemann; Jan C van Meurs; Frank D Verbraak; Theo Smit; Camiel Boon; Arthur A Bergen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6062. doi:

Retinal Cell Biology July 2017

TNFα-Induced Disruption of the Blood–Retinal Barrier In Vitro Is Regulated by Intracellular 3′,5′-Cyclic Adenosine Monophosphate Levels

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Anne-Eva van der Wijk; Ilse M. C. Vogels; Cornelis J. F. van Noorden; Ingeborg Klaassen; Reinier O. Schlingemann
TAGS: adenosine monophosphate, blood-retinal barrier, permeability, cyclic amp
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3496-3505. doi: 10.1167/iovs.16-21091

Includes: Supplemental Content

Retina November 2016

Association of Circulating Markers With Outcome Parameters in the Bevacizumab and Ranibizumab in Diabetic Macular Edema Trial

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Ward Fickweiler; Ingeborg Klaassen; Ilse M. C. Vogels; Johanna M. M. Hooymans; Bruce H. R. Wolffenbuttel; Leonoor I. Los; Reinier O. Schlingemann; for the BRDME Research Group
TAGS: biological markers, plasma, rhodopsin, rna, messenger, visual acuity, eye, bevacizumab, macular edema, diabetic, ranibizumab, anti-vascular endothelial growth factor therapy
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6234-6241. doi: 10.1167/iovs.16-20157

ARVO Annual Meeting Abstract September 2016

Type 2 diabetes mellitus patients with white dots in the central fundus and neuroretinal degeneration

Stanley Darma; Reinier O. Schlingemann; Pauline Kok; Michael David Abramoff; Frits Holleman; Frank D Verbraak

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4238. doi:

Retina March 2016

HIV-Associated Neuroretinal Disorder in Patients With Well-Suppressed HIV-Infection: A Comparative Cohort Study

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Nazli Demirkaya; Ferdinand W. N. M. Wit; Thomas J. T. P. van Den Berg; Katherine W. Kooij; Maria Prins; Reinier O. Schlingemann; Michael D. Abramoff; Peter Reiss; Frank D. Verbraak; on behalf of the AGEhIV Cohort Study Group
TAGS: hiv, cohort studies, contrast sensitivity, hiv infections
Invest. Ophthalmol. Vis. Sci.. 2016; 57(3):1388-1397. doi: 10.1167/iovs.15-18537

Retina June 2015

Retinal Structure and Function in Perinatally HIV-Infected and cART-Treated Children: A Matched Case–Control Study

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Nazli Demirkaya; Sophie Cohen; Ferdinand W. N. M. Wit; Michael D. Abramoff; Reinier O. Schlingemann; Taco W. Kuijpers; Peter Reiss; Dasja Pajkrt; Frank D. Verbraak
TAGS: hiv, child, vision, retina
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):3945-3954. doi: 10.1167/iovs.15-16855

New Developments in Vision Research November 2014

The RD5000 Database: Facilitating Clinical, Genetic, and Therapeutic Studies on Inherited Retinal Diseases

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Ramon A. C. van Huet; Clasien J. Oomen; Astrid S. Plomp; Maria M. van Genderen; B. Jeroen Klevering; Reinier O. Schlingemann; Caroline C. W. Klaver; L. Ingeborgh van den Born; Frans P. M. Cremers; the RD5000 Study Group
TAGS: retinal diseases, genetics
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7355-7360. doi: 10.1167/iovs.14-15317

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Comparing the effectiveness of bevacizumab to ranibizumab in patients with exudative age-related macular degeneration. BRAMD

Ann-Sofie Marie Evelyn Schauwvlieghe; Greetje Dijkman; Johanna M M Hooymans; Frank D Verbraak; Marcel G Dijkgraaf; Tunde Peto; Johannes R Vingerling; Carel Hoyng; Reinier O Schlingemann; BRAMD Study Group

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):870. doi:

ARVO Annual Meeting Abstract April 2014

PLVAP Modulates Angiogenesis By Tuning VEGF Signaling In Endothelial Cells

Joanna Wisniewska-Kruk; Ingeborg Klaassen; Ilse M Vogels; Cornelis J Van Noorden; Reinier O Schlingemann; Ocular Angiogenesis Group

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2241. doi:

ARVO Annual Meeting Abstract April 2014

Progressive Thinning of Inner Retinal Layer Thickness Over Time in Diabetic Patients

Hille Van Dijk; Michael David Abramoff; Ferdinand Wit; Mirjam EJ Van Velthoven; Reinier O Schlingemann; Frank D Verbraak

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4428. doi:

ARVO Annual Meeting Abstract April 2014

Results of Single spot limited PDT in patients with choroidal haemangioma

Marilette Stehouwer; Jan E Keunen; Reinier O Schlingemann; Frank D Verbraak

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3096. doi:

Retinal Cell Biology October 2013

Complement Factor C3a Alters Proteasome Function in Human RPE Cells and in an Animal Model of Age-Related RPE Degeneration

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J. Emanuel Ramos de Carvalho; Ingeborg Klaassen; Ilse M. C. Vogels; Sabine Schipper-Krom; Cornelis J. F. van Noorden; Eric Reits; Theo G. M. F. Gorgels; Arthur A. B. Bergen; Reinier O. Schlingemann
TAGS: complement system proteins, multicatalytic endopeptidase complex, tissue degeneration, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2013; 54(10):6489-6501. doi: 10.1167/iovs.13-12374

Retina July 2013

Effect of Age on Individual Retinal Layer Thickness in Normal Eyes as Measured With Spectral-Domain Optical Coherence Tomography

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Nazli Demirkaya; Hille W. van Dijk; Sanne M. van Schuppen; Michael D. Abràmoff; Mona K. Garvin; Milan Sonka; Reinier O. Schlingemann; Frank D. Verbraak
TAGS: eye, optical coherence tomography, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2013; 54(7):4934-4940. doi: 10.1167/iovs.13-11913

Retina December 2012

Evolution of Outer Retinal Folds Occurring after Vitrectomy for Retinal Detachment Repair

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Roberto dell'Omo; H. Stevie Tan; Reinier O. Schlingemann; Heico M. Bijl; Sarit Y. Lesnik Oberstein; Francesco Barca; Marco Mura
TAGS: renal artery stenosis, renin-angiotensin-aldosterone system, rotational atherectomy, follow-up, open reading frames, photoreceptors, vitrectomy, eye, reticular activating system, autofluorescence, fundus autofluorescence imaging, detached retina repairs
Invest. Ophthalmol. Vis. Sci.. 2012; 53(13):7928-7935. doi: 10.1167/iovs.12-10322

Includes: Supplemental Content

Retina May 2012

Early Neurodegeneration in the Retina of Type 2 Diabetic Patients

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Hille W. van Dijk; Frank D. Verbraak; Pauline H. B. Kok; Marilette Stehouwer; Mona K. Garvin; Milan Sonka; J. Hans DeVries; Reinier O. Schlingemann; Michael D. Abràmoff
TAGS: diabetes mellitus, diabetes mellitus, type 2, hemoglobin a, glycosylated, nerve degeneration, retina
Invest. Ophthalmol. Vis. Sci.. 2012; 53(6):2715-2719. doi: 10.1167/iovs.11-8997

ARVO Annual Meeting Abstract March 2012

Pericentral Ganglion Cell Layer Thickness Decreases with Age in Normal Eyes as Measured by Spectral-Domain Optical Coherence Tomography

Nazli Demirkaya; Hille W. van Dijk; Reinier O. Schlingemann; Michael D. Abramoff; Mona K. Garvin; Milan Sonka; Frank D. Verbraak

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):823. doi:

Retina July 2010

Decreased Retinal Ganglion Cell Layer Thickness in Patients with Type 1 Diabetes

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Hille W. van Dijk; Frank D. Verbraak; Pauline H. B. Kok; Mona K. Garvin; Milan Sonka; Kyungmoo Lee; J. Hans DeVries; Robert P. J. Michels; Mirjam E. J. van Velthoven; Reinier O. Schlingemann; Michael D. Abràmoff
TAGS: diabetes mellitus, diabetes mellitus, type 1, diabetes mellitus, type 2, hemoglobin a, glycosylated, macula lutea, retinal ganglion cells, macula densa, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2010; 51(7):3660-3665. doi: 10.1167/iovs.09-5041

Biochemistry and Molecular Biology April 2010

Differential TGF-β Signaling in Retinal Vascular Cells: A Role in Diabetic Retinopathy?

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Rob J. Van Geest; Ingeborg Klaassen; Ilse M. C. Vogels; Cornelis J. F. Van Noorden; Reinier O. Schlingemann
TAGS: signal transduction, endothelial cells, diabetic retinopathy, phosphorylation, rna, messenger, proteins
Invest. Ophthalmol. Vis. Sci.. 2010; 51(4):1857-1865. doi: 10.1167/iovs.09-4181

Retina July 2009

Selective Loss of Inner Retinal Layer Thickness in Type 1 Diabetic Patients with Minimal Diabetic Retinopathy

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Hille W. van Dijk; Pauline H. B. Kok; Mona Garvin; Milan Sonka; J. Hans DeVries; Robert P. J. Michels; Mirjam E. J. van Velthoven; Reinier O. Schlingemann; Frank D. Verbraak; Michael D. Abràmoff
TAGS: diabetes mellitus, diabetes mellitus, type 1, diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.. 2009; 50(7):3404-3409. doi: 10.1167/iovs.08-3143

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Comparing the efficacy of bevacizumab to ranibizumab in patients with diabetic macular edema: the BRDME study

Sodium iodate-induced retinal degeneration in small animal models for Age-related Macular degeneration

TNFα-Induced Disruption of the Blood–Retinal Barrier In Vitro Is Regulated by Intracellular 3′,5′-Cyclic Adenosine Monophosphate Levels

Association of Circulating Markers With Outcome Parameters in the Bevacizumab and Ranibizumab in Diabetic Macular Edema Trial

Type 2 diabetes mellitus patients with white dots in the central fundus and neuroretinal degeneration

HIV-Associated Neuroretinal Disorder in Patients With Well-Suppressed HIV-Infection: A Comparative Cohort Study

Retinal Structure and Function in Perinatally HIV-Infected and cART-Treated Children: A Matched Case–Control Study

The RD5000 Database: Facilitating Clinical, Genetic, and Therapeutic Studies on Inherited Retinal Diseases

Comparing the effectiveness of bevacizumab to ranibizumab in patients with exudative age-related macular degeneration. BRAMD

PLVAP Modulates Angiogenesis By Tuning VEGF Signaling In Endothelial Cells

Progressive Thinning of Inner Retinal Layer Thickness Over Time in Diabetic Patients

Results of Single spot limited PDT in patients with choroidal haemangioma

Complement Factor C3a Alters Proteasome Function in Human RPE Cells and in an Animal Model of Age-Related RPE Degeneration

Effect of Age on Individual Retinal Layer Thickness in Normal Eyes as Measured With Spectral-Domain Optical Coherence Tomography

Evolution of Outer Retinal Folds Occurring after Vitrectomy for Retinal Detachment Repair

Early Neurodegeneration in the Retina of Type 2 Diabetic Patients

Pericentral Ganglion Cell Layer Thickness Decreases with Age in Normal Eyes as Measured by Spectral-Domain Optical Coherence Tomography

Decreased Retinal Ganglion Cell Layer Thickness in Patients with Type 1 Diabetes

Differential TGF-β Signaling in Retinal Vascular Cells: A Role in Diabetic Retinopathy?

Selective Loss of Inner Retinal Layer Thickness in Type 1 Diabetic Patients with Minimal Diabetic Retinopathy

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