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ARVO Annual Meeting Abstract June 2022

AAV5 -RPGR (botaretigene sparoparvovec) gene therapy for X-linked retinitis pigmentosa (XLRP) demonstrates localized improvements in static perimetry

Michel Michaelides; Jialin Xu; Dai Wang; Peggy Wong; Albert Fung; Alexandra Forbes; Stuart Naylor; Robert Zeldin; Maria A Parker; Richard Weleber; Thales Antonio Cabral de Guimaraes; Cagri Besirli; Yesa Yang; James Bainbridge

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3846. doi:

Retina November 2020

Genotype Phenotype Correlation and Variability in Microcephaly Associated With Chorioretinopathy or Familial Exudative Vitreoretinopathy

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Maria F. Shurygina; Joseph M. Simonett; Maria A. Parker; Amanda Mitchell; Florin Grigorian; Jacob Lifton; Aaron Nagiel; Alexander A. Shpak; Elena L. Dadali; Irina A. Mishina; Richard G. Weleber; Paul Yang; Mark E. Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):2. doi: https://doi.org/10.1167/iovs.61.13.2

Includes: Supplemental Content

Retina September 2020

Long-Term Investigation of Retinal Function in Patients with Achromatopsia

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Michalis Georgiou; Navjit Singh; Thomas Kane; Serena Zaman; Nashila Hirji; Jonathan Aboshiha; Neruban Kumaran; Angelos Kalitzeos; Joseph Carroll; Richard G. Weleber; Michel Michaelides
TAGS: achromatopsia, eye, follow-up, cohort studies, genotype
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):38. doi: https://doi.org/10.1167/iovs.61.11.38

Includes: Supplemental Content

Retina August 2020

Suppression of cGMP-Dependent Photoreceptor Cytotoxicity With Mycophenolate Is Neuroprotective in Murine Models of Retinitis Pigmentosa

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Paul Yang; Rachel Lockard; Hope Titus; Jordan Hiblar; Kyle Weller; Dahlia Wafai; Richard G. Weleber; Robert M. Duvoisin; Catherine W. Morgans; Mark E. Pennesi
TAGS: cyclic gmp, cytotoxicity, mice, photoreceptors, mycophenolate mofetil, retinitis pigmentosa
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):25. doi: https://doi.org/10.1167/iovs.61.10.25

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Neuroprotective Mechanisms of Dark Rearing on cGMP in rd10 mice

Paul Yang; Hope Titus; Jordan Hiblar; Dahlia Wafai; Robert M Duvoisin; Richard G Weleber; Catherine W Morgans; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2482. doi:

ARVO Annual Meeting Abstract July 2019

Early Treatment with Mycophenolate Reduces Microglial Migration in rd10 mice

Paul Yang; Hope Titus; Kyle Weller; Robert Duvoisin; Richard Weleber; Catherine W Morgans; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):453. doi:

ARVO Annual Meeting Abstract July 2019

Neuroprotective Mechanisms of Dark Rearing in rd10 mice

Hope Titus; Kyle Weller; Rachel Lockard; Richard Weleber; Mark E Pennesi; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4887. doi:

Retina December 2018

Prospective Evaluation of Patients With X-Linked Retinoschisis During 18 Months

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Mark E. Pennesi; David G. Birch; K. Thiran Jayasundera; Maria Parker; Ou Tan; Rabia Gurses-Ozden; Carrie Reichley; Kathleen N. Beasley; Paul Yang; Richard G. Weleber; Lea D. Bennett; John R. Heckenlively; Kalyani Kothapalli; Jeffrey D. Chulay; for the XLRS-001 Study Group
TAGS: cysts, electroretinography, eye, perimetry, vision, visual acuity, volume, x-linked retinoschisis, contrast sensitivity, cutaneous collagenous vasculopathy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5941-5956. doi: https://doi.org/10.1167/iovs.18-24565

Includes: Supplemental Content

Articles November 2018

Cross-Sectional and Longitudinal Assessment of Retinal Sensitivity in Patients With Childhood-Onset Stargardt Disease

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Preena Tanna; Michalis Georgiou; Jonathan Aboshiha; Rupert W. Strauss; Neruban Kumaran; Angelos Kalitzeos; Richard G. Weleber; Michel Michaelides
TAGS: adult, child, perimetry, reliability, stargardt's disease, eye
Trans. Vis. Sci. Tech.. 2018; 7(6):10. doi: https://doi.org/10.1167/tvst.7.6.10

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Outer Retinal Tubulations in Boucher-Neuhauser Syndrome

Terry Wood; Richard G Weleber

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1538. doi:

ARVO Annual Meeting Abstract July 2018

Test-Retest Variability of Functional and Structural Parameters in patients with Usher Syndrome Type-1B (USH1B)

Maria A Parker; Andreas Lauer; Tim Stout; Mark E Pennesi; Paul Yang; David J Wilson; Dongseok Choi; Laura R Erker; Brandon J Lujan; Ou Tan; Pierre-Olivier Barale; Caroline Cohen; Saddek Mohand-Said; Isabelle S Audo; Jose A. Sahel; Richard G Weleber

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3896. doi:

ARVO Annual Meeting Abstract July 2018

Projection-Resolved Optical Coherence Tomography Angiography of Retinal Plexusess in Retinitis Pigmentosa and Usher Syndrome Type 1

Ahmed M Hagag; JIE WANG; Terry Wood; Joseph Michael Simonett; Gareth Harman; Kevin Liu; David Huang; Richard G Weleber; Mark E Pennesi; Paul Yang; Yali Jia

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2842. doi:

ARVO Annual Meeting Abstract July 2018

Software for digitization and three-dimensional volumetric measurement of Kinetic Perimetry

Laura R Erker; Ellie Chegarnov; Maria A Parker; Mitra Adeli; Edye Parker; Travis Smith; Claire Barnes; Melissa Broemeling; David J Wilson; Richard G Weleber

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1269. doi:

ARVO Annual Meeting Abstract July 2018

Dark-rearing reduces degeneration and alters the characteristics of cGMP dysregulation in rd10 mice

Hope Titus; Kyle K. Weller; Jenny Li; Richard G Weleber; Mark E Pennesi; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1001. doi:

ARVO Annual Meeting Abstract July 2018

Next Generation Sequencing in Pigmented Paravenous Retinochoroidal Atrophy

Huber Martins Vasconcelos; Amanda Mitchell; Florin Gregorian; Pei-Wen Chiang; Rui Chen; Yumei Li; Richard G Weleber; Mark E Pennesi; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2339. doi:

ARVO Annual Meeting Abstract July 2018

Early Treatment with Mycophenolate Mofetil Reduces Retinal Degeneration and cGMP Dysregulation in rd10 and rd1 mice

Paul Yang; Rachel Lockard; Hope E. Titus; Kyle K. Weller; Aaron S Coyner; Robert M Duvoisin; Richard G Weleber; Catherine W Morgans; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2503. doi:

ARVO Annual Meeting Abstract July 2018

Intravitreal Anti-VEGF Therapy for Choroidal Neovascularization-Associated with Best Vitelliform Macular Dystrophy

Florin Grigorian; Huber Martins Vasconcelos; Steven T Bailey; Brandon J Lujan; J. Peter Campbell; Phoebe Lin; Richard G Weleber; Mark E Pennesi; Paul Yang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3145. doi:

Clinical and Epidemiologic Research July 2018

A Cross-Sectional and Longitudinal Study of Retinal Sensitivity in RPE65 -Associated Leber Congenital Amaurosis

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Neruban Kumaran; Gary S. Rubin; Angelos Kalitzeos; Kaoru Fujinami; James W. B. Bainbridge; Richard G. Weleber; Michel Michaelides
TAGS: contrast sensitivity, eye, genotype, leber's amaurosis, longitudinal studies, perimetry, vision, visual acuity, visual fields, reliability
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3330-3339. doi: https://doi.org/10.1167/iovs.18-23873

Includes: Supplemental Content

Genetics May 2018

Characterization of Visual Function, Interocular Variability and Progression Using Static Perimetry–Derived Metrics in RPGR -Associated Retinopathy

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James J. L. Tee; Yesa Yang; Angelos Kalitzeos; Andrew Webster; James Bainbridge; Richard G. Weleber; Michel Michaelides
TAGS: baseline value, perimetry, retinal diseases, retinitis pigmentosa, vision, genotype
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2422-2436. doi: https://doi.org/10.1167/iovs.17-23739

ARVO Annual Meeting Abstract June 2017

Safety Profile of the Surgical Procedure for the Administration of Ocular Gene Therapies

Ronald BUGGAGE; Pierre-Olivier Barale; Sarah Ayello-Scheer; Andreas K Lauer; Tim Stout; Isabelle S Audo; Saddek Mohand-Said; Jose Alain Sahel; Paul Yang; Mark E Pennesi; Richard G Weleber; Laurence Titeux; Amel Lahmar; Preethi A Sundaram

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1491. doi:

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AAV5 -RPGR (botaretigene sparoparvovec) gene therapy for X-linked retinitis pigmentosa (XLRP) demonstrates localized improvements in static perimetry

Genotype Phenotype Correlation and Variability in Microcephaly Associated With Chorioretinopathy or Familial Exudative Vitreoretinopathy

Long-Term Investigation of Retinal Function in Patients with Achromatopsia

Suppression of cGMP-Dependent Photoreceptor Cytotoxicity With Mycophenolate Is Neuroprotective in Murine Models of Retinitis Pigmentosa

Neuroprotective Mechanisms of Dark Rearing on cGMP in rd10 mice

Early Treatment with Mycophenolate Reduces Microglial Migration in rd10 mice

Neuroprotective Mechanisms of Dark Rearing in rd10 mice

Prospective Evaluation of Patients With X-Linked Retinoschisis During 18 Months

Cross-Sectional and Longitudinal Assessment of Retinal Sensitivity in Patients With Childhood-Onset Stargardt Disease

Outer Retinal Tubulations in Boucher-Neuhauser Syndrome

Test-Retest Variability of Functional and Structural Parameters in patients with Usher Syndrome Type-1B (USH1B)

Projection-Resolved Optical Coherence Tomography Angiography of Retinal Plexusess in Retinitis Pigmentosa and Usher Syndrome Type 1

Software for digitization and three-dimensional volumetric measurement of Kinetic Perimetry

Dark-rearing reduces degeneration and alters the characteristics of cGMP dysregulation in rd10 mice

Next Generation Sequencing in Pigmented Paravenous Retinochoroidal Atrophy

Early Treatment with Mycophenolate Mofetil Reduces Retinal Degeneration and cGMP Dysregulation in rd10 and rd1 mice

Intravitreal Anti-VEGF Therapy for Choroidal Neovascularization-Associated with Best Vitelliform Macular Dystrophy

A Cross-Sectional and Longitudinal Study of Retinal Sensitivity in RPE65 -Associated Leber Congenital Amaurosis

Characterization of Visual Function, Interocular Variability and Progression Using Static Perimetry–Derived Metrics in RPGR -Associated Retinopathy

Safety Profile of the Surgical Procedure for the Administration of Ocular Gene Therapies

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