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Retinal Cell Biology December 2024

Elevation of Granulocyte Colony Stimulating Factor in Human AMD Donor RPE-Choroid

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Kelly Mulfaul; Adnan H. Khan; Samantha G. Schwarte; Andrew P. Voigt; Rachel F. Moore; Lawrence A. Potempa; Kai Wang; Todd E. Scheetz; Edwin M. Stone; Budd A. Tucker; Robert F. Mullins
TAGS: choroid, donors, granulocyte colony-stimulating factor, proteins, recombinant granulocyte colony stimulating factor, body tissue
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):15. https://doi.org/10.1167/iovs.65.14.15

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Characterization and gene-based treatment of a novel CRISPR-Cas9 generated Mak -deficient rat model of photoreceptor degeneration

Lorena Haefeli; Luke A Wiley; Cathryn Cranston; Heather Daggett; Ian Han; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2216.

ARVO Annual Meeting Abstract June 2024

Complement injury and CRP stress alter inflammatory cytokine secretion in AMD iPSC derived choroidal endothelial cells.

Kelly Mulfaul; Samantha G Schwarte; Megan J Riker; Brynnon E Harman; Edwin M Stone; Budd A. Tucker; Robert F Mullins

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):736.

ARVO Annual Meeting Abstract June 2024

iPSC derived choroidal endothelial cell delivery using laminin-based hydrogels for the treatment of AMD

Narendra Pandala; Ian Han; Emily Meyering; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1542.

ARVO Annual Meeting Abstract June 2024

Development of chemically induced choroidal injury models for the study and treatment of AMD.

Ian Han; Narendra Pandala; Lorena Haefeli; Mallory J Lang; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5382.

ARVO Annual Meeting Abstract June 2024

Transplantation of cGMP compliant iPSC-derived retinal progenitor cells

Laura R Bohrer; Luke A Wiley; Allison T Wright; Louisa Affatigato; Robert F Mullins; Edwin M Stone; Ian Han; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1541.

ARVO Annual Meeting Abstract June 2024

miR-181 expression and inhibition: a potential new treatment for dominant rhodopsin associated retinitis pigmentosa.

Renato Jensen; Lorena Haefeli; Luke A Wiley; Colleen Stein; Jessica L Fick; Malia Collins; Robert F Mullins; Ian Han; Edwin M Stone; Ryan Boudreau; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2215.

ARVO Annual Meeting Abstract June 2024

Retinal differentiation propensity is linked to pluripotency factor localization and donor cell epigenetic memory.

Jessica A Cooke; Nathaniel Kevin Mullin; Douglas B Critser; Edwin M Stone; Robert F Mullins; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1543.

ARVO Annual Meeting Abstract June 2024

A dual AAV vector approach for the treatment of ABCA4 -associated retinal disease.

Erin R Burnight; Luke A Wiley; Dalyz Ochoa; Katayoun Varzavand; Seongjin Seo; Ian Han; Robert F Mullins; Edwin M Stone; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1540.

ARVO Annual Meeting Abstract June 2024

The role of nicotinamide N-methyltransferase in choroidal endothelial cells: possible role in macular neovascularization

Emma Mae Navratil; Miles J Flamme-Wiese; Adnan Khan; Xiuying Liu; Luke A Wiley; Edwin M Stone; Budd A. Tucker; Robert F Mullins

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4969.

ARVO Annual Meeting Abstract June 2024

The NR2E3 variant c.932G>A (p.Arg311Gln) creates an alternative splice acceptor leading to an in-frame deletion of 186 nucleotides

Nathaniel Kevin Mullin; Laura R Bohrer; Kristin R Anfinson; Jeaneen L Andorf; Robert F Mullins; Budd A. Tucker; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4514.

ARVO Annual Meeting Abstract June 2024

Heteroplasmy distribution in human retinal mitochondrial disease

Robert F Mullins

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6470.

ARVO Annual Meeting Abstract June 2024

Developing a molecular assay to predict hemangioblastoma phenotype severity in VHL disease

Lola Lozano; Edwin M Stone; Robert F Mullins; Budd A. Tucker; Elaine Binkley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6033.

ARVO Annual Meeting Abstract June 2024

Device-free isolation of photoreceptors from patient stem cell derived retinal organoids

Nicholas Edwin Stone; Laura R Bohrer; Nathaniel Kevin Mullin; Robert F Mullins; Edwin M Stone; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):950.

Retinal Cell Biology October 2023

Gene Expression Within a Human Choroidal Neovascular Membrane Using Spatial Transcriptomics

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Andrew P. Voigt; Nathaniel K. Mullin; Emma M. Navratil; Miles J. Flamme-Wiese; Li-Chun Lin; Todd E. Scheetz; Ian C. Han; Edwin M. Stone; Budd A. Tucker; Robert F. Mullins
TAGS: choroidal neovascularization, gene expression, macular neovascularization, genes, sequence analysis, rna, donors, choroid, eye
Invest. Ophthalmol. Vis. Sci.. 2023; 64(13):40. https://doi.org/10.1167/iovs.64.13.40

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

MMP9 associated with choroidal neovascularization in AMD is expressed in human immune cells

Elliott H Sohn; Chunhua Jiao; Andrew P Voigt; Todd E Scheetz; Robert F Mullins

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):27.

ARVO Annual Meeting Abstract June 2022

Molecular Characterization of Neovascular AMD in Human Eyes using Spatial Transcriptomics and Single Cell RNA Sequencing

Robert F Mullins; Andrew P Voigt; Todd E Scheetz; Nathaniel Kevin Mullin; Miles J Flamme-Wiese; Li-Chun Lin; Edwin M Stone; Ian Han; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2316.

ARVO Annual Meeting Abstract June 2022

Non-random cellular distribution of the mitochondrial 3243A>G variant in the human retina and choroid and its impact on disease phenotype.

Nathaniel Kevin Mullin; Andrew P Voigt; Miles J Flamme-Wiese; Xiuying Liu; Kelsey L Wieland; Edwin M Stone; Budd A. Tucker; Robert F Mullins

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2654.

ARVO Annual Meeting Abstract June 2022

cGMP compliant CRISPR correction and retinal differentiation protocol for photoreceptor cell replacement therapy

Laura R Bohrer; Nicholas E Stone; Allison T Wright; Katayoun Varzavand; Melette Devore; Sewoon Han; Todd A Sulchek; Robert F Mullins; Edwin M Stone; Budd A. Tucker

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1356 – F0287.

ARVO Annual Meeting Abstract June 2022

Automated production of patient derived iPSCs for autologous photoreceptor cell replacement.

Budd A. Tucker; Laura R Bohrer; Nicholas E Stone; Kristin R. Anfinson; Cathryn M. Schaffer; Meagan A Luse; Bradley A. Hittle; Kimerly A. Powell; George F. Muschler; Robert F Mullins; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1860.

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Elevation of Granulocyte Colony Stimulating Factor in Human AMD Donor RPE-Choroid

Characterization and gene-based treatment of a novel CRISPR-Cas9 generated Mak -deficient rat model of photoreceptor degeneration

Complement injury and CRP stress alter inflammatory cytokine secretion in AMD iPSC derived choroidal endothelial cells.

iPSC derived choroidal endothelial cell delivery using laminin-based hydrogels for the treatment of AMD

Development of chemically induced choroidal injury models for the study and treatment of AMD.

Transplantation of cGMP compliant iPSC-derived retinal progenitor cells

miR-181 expression and inhibition: a potential new treatment for dominant rhodopsin associated retinitis pigmentosa.

Retinal differentiation propensity is linked to pluripotency factor localization and donor cell epigenetic memory.

A dual AAV vector approach for the treatment of ABCA4 -associated retinal disease.

The role of nicotinamide N-methyltransferase in choroidal endothelial cells: possible role in macular neovascularization

The NR2E3 variant c.932G>A (p.Arg311Gln) creates an alternative splice acceptor leading to an in-frame deletion of 186 nucleotides

Heteroplasmy distribution in human retinal mitochondrial disease

Developing a molecular assay to predict hemangioblastoma phenotype severity in VHL disease

Device-free isolation of photoreceptors from patient stem cell derived retinal organoids

Gene Expression Within a Human Choroidal Neovascular Membrane Using Spatial Transcriptomics

MMP9 associated with choroidal neovascularization in AMD is expressed in human immune cells

Molecular Characterization of Neovascular AMD in Human Eyes using Spatial Transcriptomics and Single Cell RNA Sequencing

Non-random cellular distribution of the mitochondrial 3243A>G variant in the human retina and choroid and its impact on disease phenotype.

cGMP compliant CRISPR correction and retinal differentiation protocol for photoreceptor cell replacement therapy

Automated production of patient derived iPSCs for autologous photoreceptor cell replacement.

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