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Journal Articles (7)
Meeting Abstract (4)

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Investigative Ophthalmology & Visual Science (11)

Article Type

Anatomy and Pathology/Oncology (6)
ARVO Annual Meeting Abstract (4)
Genetics (1)

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Eye Anatomy and Disorders (7)
Oncology (7)
Genetics (5)
Immunology and Microbiology (2)
External Eye Disease (1)

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intraocular melanoma (6)
neoplasm metastasis (5)
neoplasms (5)
chromosomes (3)
mutation (3)
atypical (2)
bap1 gene (2)
chemokine receptors (2)
conjunctiva (2)
cxcr4 receptors (2)

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Anatomy and Pathology/Oncology August 2019

Multi-Modality Analysis Improves Survival Prediction in Enucleated Uveal Melanoma Patients

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Wojtek Drabarek; Serdar Yavuzyigitoglu; Askar Obulkasim; Job van Riet; Kyra N. Smit; Natasha M. van Poppelen; Jolanda Vaarwater; Tom Brands; Bert Eussen; Robert M. Verdijk; Nicole C. Naus; Hanneke W. Mensink; Dion Paridaens; Eric Boersma; Harmen J. G. van de Werken; Emine Kilic; Annelies de Klein; for the Rotterdam Ocular Melanoma Study Group
TAGS: copy number polymorphism, histopathology tests, intraocular melanoma, mutation, neoplasms, single nucleotide polymorphism, bap1 gene, neoplasm metastasis, sf3b1 gene, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3595-3605. doi: 10.1167/iovs.18-24818

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Soluble HLA in the aqueous humour as risk factor or a marker of inflammation in uveal melanoma

Annemijn Philine Annette Wierenga; Gulcin Gezgin; Els van Beelen; Michael Eikmans; Mieke Versluis; Robert M. Verdijk; Sjoerd van Duinen; Marina Marinkovic; Gregorius P.M. Luyten; Martine J Jager

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):740. doi:

ARVO Annual Meeting Abstract July 2019

Prognostication of uveal melanoma patients: are exosomes the solution?

Emine Kilic; Kyra Smit; Natasha van Poppelen; Taran Lunavat; Jolanda Vaarwater; Su Chul Jang; Robert M. Verdijk; Jan Lötvall; Annelies de Klein

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):749. doi:

Anatomy and Pathology/Oncology July 2019

Chemokine Receptor Expression Pattern Correlates to Progression of Conjunctival Melanocytic Lesions

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Jolique A. van Ipenburg; Nadine E. de Waard; Nicole C. Naus; Martine J. Jager; Dion Paridaens; Robert M. Verdijk
TAGS: atypical, chemokine receptors, chemokines, conjunctiva, cxcr4 receptors, melanoma, nevus, neoplasm metastasis, immune reconstitution inflammatory syndrome, insulin receptor substrate proteins
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2950-2957. doi: 10.1167/iovs.19-27162

Anatomy and Pathology/Oncology April 2016

Metastatic Disease in Polyploid Uveal Melanoma Patients Is Associated With BAP1 Mutations

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Serdar Yavuzyigitoglu; Hanneke W. Mensink; Kyra N. Smit; Jolanda Vaarwater; Robert M. Verdijk; Berna Beverloo; Hennie T. Brüggenwirth; Ronald van Marion; Hendrikus J. Dubbink; Dion Paridaens; Nicole C. Naus; Annelies de Klein; Emine Kiliç; for the Rotterdam Ocular Melanoma Study Group (ROMS),
TAGS: mutation, genes, neoplasm metastasis, ploidies, polyploidy, neoplasms, intraocular melanoma, bap1 gene
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):2232-2239. doi: 10.1167/iovs.15-18608

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Mitogen-activated protein kinase (MAPK) inhibitors in conjunctival melanoma cell lines

Jinfeng Cao; Robert M. Verdijk; Aart G. Jochemsen; Martine J Jager

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1287. doi:

ARVO Annual Meeting Abstract June 2015

Loss of BAP1 expression is associated with increased angiogenesis in uveal melanoma

Gülçin Gezgin; Inge H.G. Bronkhorst; T Huibertus Van Essen; Sake van Pelt; Robert M. Verdijk; Pieter A. van der Velden; Gregorius P M Luyten; Thorbald van Hall; Sjoerd H van der Burg; Martine J Jager

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5323. doi:

Anatomy and Pathology/Oncology September 2014

Prevalence and Implications of TERT Promoter Mutation in Uveal and Conjunctival Melanoma and in Benign and Premalignant Conjunctival Melanocytic Lesions

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Anna E. Koopmans; Kimberley Ober; Hendrikus J. Dubbink; Dion Paridaens; Nicole C. Naus; Stephan Belunek; Bart Krist; Edward Post; Ellen C. Zwarthoff; Annelies de Klein; Robert M. Verdijk
TAGS: mutation, precancerous conditions, conjunctiva, prevalence, uvea, malignant melanoma of conjunctiva, intraocular melanoma, atypical, eye melanomas
Invest. Ophthalmol. Vis. Sci.. 2014; 55(9):6024-6030. doi: 10.1167/iovs.14-14901

Anatomy and Pathology/Oncology March 2014

The Prognostic Value of Extraocular Extension in Relation to Monosomy 3 and Gain of Chromosome 8q in Uveal Melanoma

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Jackelien G. M. van Beek; Anna E. Koopmans; Jolanda Vaarwater; Johan J. de Rooi; Dion Paridaens; Nicole C. Naus; Annelies de Klein; Robert M. Verdijk; Emine Kiliç
TAGS: chromosomes, monosomy, neoplasm metastasis, neoplasms, intraocular melanoma, diameter, extension
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1284-1291. doi: 10.1167/iovs.13-13670

Anatomy and Pathology/Oncology November 2013

Chemokine Receptor CCR7 Expression Predicts Poor Outcome in Uveal Melanoma and Relates to Liver Metastasis Whereas Expression of CXCR4 Is Not of Clinical Relevance

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Thierry van den Bosch; Anna E. Koopmans; Jolanda Vaarwater; Mike van den Berg; Annelies de Klein; Robert M. Verdijk
TAGS: neoplasm metastasis, chemokine receptors, cxcr4 receptors, neoplasms, liver metastases, stromal cell-derived factor 1, intraocular melanoma
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7354-7361. doi: 10.1167/iovs.13-12407

Genetics May 2012

Higher Percentage of FISH-Determined Monosomy 3 and 8q Amplification in Uveal Melanoma Cells relate to Poor Patient Prognosis

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Thomas van den Bosch; Jackelien G. M. van Beek; Jolanda Vaarwater; Robert M. Verdijk; Nicole C. Naus; Dion Paridaens; Annelies de Klein; Emine Kiliç
TAGS: chromosomes, monosomy, neoplasms, intraocular melanoma, amplification
Invest. Ophthalmol. Vis. Sci.. 2012; 53(6):2668-2674. doi: 10.1167/iovs.11-8697

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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