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Articles November 2018

Correlation of Optical Coherence Tomography and Retinal Histology in Normal and Pro23His Retinal Degeneration Pig

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Justine Cheng; Elliott H. Sohn; Chunhua Jiao; Kelsey L. Adler; Emily E. Kaalberg; Stephen R. Russell; Robert F. Mullins; Edwin M. Stone; Budd A. Tucker; Ian C. Han
TAGS: retinal degeneration, diagnostic imaging, eye, histology, optical coherence tomography
Trans. Vis. Sci. Tech.. 2018; 7(6):18. doi: 10.1167/tvst.7.6.18

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

TLR2 bridges oxidative damage and complement-associated pathology and is a therapeutic target for age-related macular degeneration.

Sarah Doyle; Kelly Mulfaul; Nilisha Fernando; Kathleen Chirco; Emma Connolly; Tony Ryan; Ema Ozaki; Kiva Brennan; Arvydas Maminishkis; Robert Salomon; Riccardo Natoli; Robert F Mullins; Matthew Campbell

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3475. doi:

ARVO Annual Meeting Abstract July 2018

Assessment of transduction efficiency and tropism of different adeno-associated virus (AAV) serotypes based on route of delivery in rats

Ian C Han; Chunhua Jiao; Emily E Kaalberg; Sajag Bhattarai; Erin R Burnight; Budd A Tucker; Robert F Mullins; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5657. doi:

ARVO Annual Meeting Abstract June 2017

Using pathway-specific reporter and direct conversion constructs to investigate Juvenile Neuronal Ceroid Lipofuscinosis.

Lorenzo L Lones; Erin R Burnight; Dalyz Ochoa; Joseph C Giacalone; Robert A Madumba; Robert F Mullins; Edwin M Stone; Budd Tucker; Luke A Wiley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):263. doi:

ARVO Annual Meeting Abstract June 2017

How to Distill Disease-Differentiating, Quantitative Phenotypic Patterns from OCT Data

S Scott Whitmore; Kyungmoo Lee; Adam P DeLuca; Young H Kwon; Jeremy M Hoffman; Jennifer A Halder; Robert F Mullins; Todd E Scheetz; Edwin M Stone; Michael David Abramoff

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):826. doi:

ARVO Annual Meeting Abstract June 2017

Two-Photon Polymerization of High-Resolution 3D, Biodegradable Photoreceptor Cell Scaffolds

Kristan Sorenson Worthington; Jessica R. Thompson; Brian J. Green; Spencer J. Bunn; Emily E. Kaalberg; Rebecca M. Johnston; Luke A Wiley; Robert F Mullins; Edwin M Stone; C. Allan Guymon; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3390. doi:

ARVO Annual Meeting Abstract June 2017

Preparation of Human Choroidal ECM Scaffolds to Study Cell Replacement Strategies

Kathleen R Chirco; Kristan Sorenson Worthington; Miles Flamme-Wiese; Megan Riker; Allison E Songstad; Malia M Collins; Joshua Andrade; Beatrix Ueberheide; Edwin M Stone; Budd Tucker; Robert F Mullins

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4586. doi:

ARVO Annual Meeting Abstract June 2017

The human RPE-choroid in short term organ culture: evaluation of gene expression changes

Robert F Mullins; S Scott Whitmore; Kathleen R Chirco; Grefachew Workalemahu; Shemin Zeng; Adam P DeLuca; XiuYing Liu; Jessica A Penticoff; Luke A Wiley; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):619. doi:

ARVO Annual Meeting Abstract June 2017

Characterization and Treatment of RPGR-associated Photoreceptor Disease

Joseph C Giacalone; Luke A Wiley; Erin R Burnight; Jeaneen Andorf; Luan M Streb; Louisa M Affatigato; Cathryn Cranston; Dalyz Ochoa; Robert F Mullins; Budd Tucker; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4515. doi:

ARVO Annual Meeting Abstract June 2017

Transduction of photoreceptors following subretinal injections of AAV5 and helper-dependent adenovirus in human retina ex vivo and pig retina in vivo

Brittni Scruggs; Erin R Burnight; Chunhua Jiao; Luke A Wiley; Robert F Mullins; Edwin M Stone; Budd Tucker; Elliott Sohn

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4534. doi:

ARVO Annual Meeting Abstract June 2017

Compatibility of a biodegradable retinal cell graft for the treatment of retinal degenerative blindness

Elliott Sohn; Kristan Sorenson Worthington; Chunhua Jiao; Emily E. Kaalberg; Stephen R Russell; Katherine N. Gibson-Corley; Robert F Mullins; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4585. doi:

ARVO Annual Meeting Abstract June 2017

Combining CRISPR based genome editing and patient specific iPSCs to elucidate the pathophysiologic role of WFS1 mutations in optic atrophy.

Tasneem Putliwala Sharma; Joseph C Giacalone; Erin R Burnight; Kristin R. Anfinson; Jill S. Wiley; John Fingert; Robert F Mullins; Edwin M Stone; Budd Tucker

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5585. doi:

Research Highlight February 2017

Drusen on Demand? Authors Describe a Novel Culture System for Generating subRPE Deposits

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Robert F. Mullins

Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):720-720. doi: 10.1167/iovs.17-21419

ARVO Annual Meeting Abstract September 2016

Dissociation protocol and optimal conditions for clinical-grade induced pluripotent stem cell-derived retinal precursor cells

Brittni Scruggs; Budd A Tucker; Chunhua Jiao; Janet Riley; Edwin M Stone; Robert F Mullins; Elliott H Sohn

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3736. doi:

ARVO Annual Meeting Abstract September 2016

Optimizing subretinal injection conditions for retinal gene and stem cell therapy

Elliott H Sohn; Chunhua Jiao; Brittni Scruggs; Diana Brack; Edwin M Stone; Robert F Mullins; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3738. doi:

ARVO Annual Meeting Abstract September 2016

Pathophysiology of Geographic Atrophy in AMD: Role of Choroidal Vascular Dropout

Robert F Mullins; Elliott H Sohn; Kathleen Chirco; Xiuying Liu; Kai Wang; Alexander Marneros; Li Zhang; Michael David Abramoff; Budd A Tucker; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6555. doi:

ARVO Annual Meeting Abstract September 2016

Monomeric C-reactive Protein and Altered Human Endothelial Cell Function in Age-related Macular Degeneration

Kathleen Chirco; S Scott Whitmore; Shemin Zeng; Grefachew Workalemahu; Lawrence A Potempa; Sara E Miller; Edwin M Stone; Budd A Tucker; Robert F Mullins

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6554. doi:

ARVO Annual Meeting Abstract September 2016

HUMAN DISEASE MODELING OF TRNT1 -ASSOCIATED RETINITIS PIGMENTOSA IN PATIENT-DERIVED CELLS

Tasneem P Sharma; Joseph C Giacalone; Erin R Burnight; Luke A Wiley; Jill S Wiley; Robert A Madumba; Robert F Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6060. doi:

ARVO Annual Meeting Abstract September 2016

Production of clinical-grade patient-specific iPSCs and transplantable photoreceptor precursor cells for the treatment of retinal degenerative blindness.

Budd A Tucker; Luke A Wiley; Erin R Burnight; Kristan S Worthington; Cathryn M Cranston; Kristin R Anfinson; Robert F Mullins; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6064. doi:

ARVO Annual Meeting Abstract September 2016

Modeling Enhanced S-cone Syndrome Using Patient-Specific iPSC-derived Retinal Eyecups

Luke A Wiley; Erin R Burnight; Jennifer A Halder; Jessica A Penticoff; Christine M Haas; Robert F Mullins; Edwin M Stone; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

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Correlation of Optical Coherence Tomography and Retinal Histology in Normal and Pro23His Retinal Degeneration Pig

TLR2 bridges oxidative damage and complement-associated pathology and is a therapeutic target for age-related macular degeneration.

Assessment of transduction efficiency and tropism of different adeno-associated virus (AAV) serotypes based on route of delivery in rats

Using pathway-specific reporter and direct conversion constructs to investigate Juvenile Neuronal Ceroid Lipofuscinosis.

How to Distill Disease-Differentiating, Quantitative Phenotypic Patterns from OCT Data

Two-Photon Polymerization of High-Resolution 3D, Biodegradable Photoreceptor Cell Scaffolds

Preparation of Human Choroidal ECM Scaffolds to Study Cell Replacement Strategies

The human RPE-choroid in short term organ culture: evaluation of gene expression changes

Characterization and Treatment of RPGR-associated Photoreceptor Disease

Transduction of photoreceptors following subretinal injections of AAV5 and helper-dependent adenovirus in human retina ex vivo and pig retina in vivo

Compatibility of a biodegradable retinal cell graft for the treatment of retinal degenerative blindness

Combining CRISPR based genome editing and patient specific iPSCs to elucidate the pathophysiologic role of WFS1 mutations in optic atrophy.

Drusen on Demand? Authors Describe a Novel Culture System for Generating subRPE Deposits

Dissociation protocol and optimal conditions for clinical-grade induced pluripotent stem cell-derived retinal precursor cells

Optimizing subretinal injection conditions for retinal gene and stem cell therapy

Pathophysiology of Geographic Atrophy in AMD: Role of Choroidal Vascular Dropout

Monomeric C-reactive Protein and Altered Human Endothelial Cell Function in Age-related Macular Degeneration

HUMAN DISEASE MODELING OF TRNT1 -ASSOCIATED RETINITIS PIGMENTOSA IN PATIENT-DERIVED CELLS

Production of clinical-grade patient-specific iPSCs and transplantable photoreceptor precursor cells for the treatment of retinal degenerative blindness.

Modeling Enhanced S-cone Syndrome Using Patient-Specific iPSC-derived Retinal Eyecups

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