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Retinal Cell Biology July 2020

Geographic Atrophy: Confocal Scanning Laser Ophthalmoscopy, Histology, and Inflammation in the Region of Expanding Lesions

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Vera L. Bonilha; Brent A. Bell; Jane Hu; Caroline Milliner; Gayle J. Pauer; Stephanie A. Hagstrom; Roxana A. Radu; Joe G. Hollyfield
TAGS: atrophy, diagnostic imaging, donors, eye, granules, histology, inflammation, scanning laser ophthalmoscopy, body tissue, retina
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):15. doi: https://doi.org/10.1167/iovs.61.8.15

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Complement Dysregulation is Evidenced in iPSC-derived RPE Cells from Stargardt Disease patients

Jane Hu; Nermin Kady; Ashley Macabasco; Michael B Gorin; Anna Matynia; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1507. doi:

ARVO Annual Meeting Abstract July 2019

Reduced expression of “normal” ABCA4 alleles in iPS-derived RPE cells from Stargardt Disease patients

Anna Matynia; Saravanan Karumbayaram; Samuel Strom; Jane Hu; Nermin Kady; Roxana A Radu; Michael B Gorin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):388. doi:

ARVO Annual Meeting Abstract July 2019

RGR opsin and RDH10 in Müller Cells Affect Light Dependent Synthesis of Chromophore Precursor for Cone Pigment Regeneration

Gabriel H Travis; Avian Tsan; Jeremy D Cook; Ala Morshedian; Lilly Yuan; Eunice Ng; Tongzhou Xu; Roxana A Radu; Gordon L Fain; Joanna J. Kaylor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2341. doi:

ARVO Annual Meeting Abstract July 2019

Retinoid recycling is impaired in Stargardt iPSC-derived RPE

Roxana A Radu; Nermin Kady; Jane Hu; Jacqueline Pei; Marcia Lloyd; Dean Bok; Michael B Gorin; Saravanan Karumbayaram; Anna Matynia

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2343. doi:

ARVO Annual Meeting Abstract July 2018

Complement C5 Inhibition as a Potential Treatment for Autosomal Recessive Stargardt Disease (STGD1): Design of a Clinical Trial Assessing a Novel Treatment and Primary Outcome Measure

Karl G Csaky; Dean Bok; Roxana A. Radu; Srinivas R. Sadda

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1569. doi:

ARVO Annual Meeting Abstract July 2018

Characterization of Stargardt iPSC-derived RPE cells

Nermin Kady; Anna Matynia; Saravanan Karumbayaram; Jane Hu; Marcia Lloyd; Dean Bok; Michael B Gorin; Roxana A. Radu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3045. doi:

ARVO Annual Meeting Abstract July 2018

Localization of ABCA4 in the Retinal Pigment Epithelium and its implications for Stargardt Disease

Tamara Lee Lenis; Sze Yin Ng; Jane Hu; Zhichun Jiang; Marcia Lloyd; Nicholas Esposito; Dean Bok; Silvia C Finnemann; Gabriel H Travis; Roxana A. Radu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4502. doi:

ARVO Annual Meeting Abstract June 2017

Expression of ABCA4 in Retinal Pigment Epithelium cells and its implications for Stargardt disease

Tamara L Lenis; Shanta Sarfare; Jane Hu; Zhichun Jiang; Marcia Lloyd; Dean Bok; Gabriel H Travis; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):607. doi:

ARVO Annual Meeting Abstract June 2017

AAV-mediated delivery of ABCA4 to the photoreceptors of Abca4 -/- mice using an overlapping dual vector strategy

Michelle E McClements; Alun R Barnard; Mandeep S Singh; Zhichun Jiang; Peter Charbel Issa; Roxana A Radu; Robert E MacLaren

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4506. doi:

ARVO Annual Meeting Abstract September 2016

Liver x receptors (LXR) at the intersection of lipid metabolism and inflammation: implications for age-related macular degeneration (AMD)

Goldis Malek; Faryan Tayyari; Mayur Choudhary; Yiyi Wang; Zhichun Jiang; Steven Nusinowitz; Roxana A Radu; Peter Tontonoz

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5011. doi:

ARVO Annual Meeting Abstract September 2016

Complement reactivity in Stargardt macular degeneration

Jane Coffman; Gayle J T Pauer; Stephanie A Hagstrom; Mary E Rayborn; Joe G Hollyfield; Dean Bok; Vera L Bonilha; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6592. doi:

ARVO Annual Meeting Abstract September 2016

Peropsin Effects Light-dependent Modulation of Retinyl Esters in the RPE

Jeremy D Cook; Eunice Ng; Marcia Lloyd; Shannan Eddington; Dean Bok; Hui Sun; Roxana A Radu; Gabriel H Travis

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1736. doi:

ARVO Annual Meeting Abstract September 2016

Elucidating the role of Retinal Pigment Epithelium (RPE)-specific ABCA4 in Stargardt disease

Tamara Lee Lenis; Zhichun Jiang; Shanta Sarfare; Andrew Le; Shannan Eddington; Dean Bok; Robert S Molday; Steven Nusinowitz; Michael Redmond; Gabriel H Travis; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3177. doi:

Retina December 2015

Monoallelic ABCA4 Mutations Appear Insufficient to Cause Retinopathy: A Quantitative Autofluorescence Study

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Philipp L. Müller; Martin Gliem; Elisabeth Mangold; Hanno J. Bolz; Robert P. Finger; Myra McGuinness; Christian Betz; Zhichun Jiang; Bernhard H. F. Weber; Robert E. MacLaren; Frank G. Holz; Roxana A. Radu; Peter Charbel Issa
TAGS: autofluorescence, mutation, phenotype, retinal diseases, mice
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8179-8186. doi: https://doi.org/10.1167/iovs.15-17629

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Characterization of the Cfh-/-Abca4-/- mouse model

Roxana A Radu; Zhichun Jiang; Jane Hu; Marcia Lloyd; Steven Nusinowitz; Dean Bok

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4655. doi:

ARVO Annual Meeting Abstract April 2014

In Situ Localization of Complement Factor H Gene Expression in the Mouse Eye

Sharon L Oltjen; Leonard M Hjelmeland; Roxana A Radu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6327. doi:

Retina August 2013

Fundus Autofluorescence in the Abca4 −/− Mouse Model of Stargardt Disease—Correlation With Accumulation of A2E, Retinal Function, and Histology

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Peter Charbel Issa; Alun R. Barnard; Mandeep S. Singh; Emma Carter; Zhichun Jiang; Roxana A. Radu; Ulrich Schraermeyer; Robert E. MacLaren
TAGS: fundus autofluorescence imaging, mice, stargardt's disease, lipofuscin, histology, granules, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2013; 54(8):5602-5612. doi: https://doi.org/10.1167/iovs.13-11688

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2013

Functional Characterization of Peropsin in the Retinal Pigment Epithelium

Jeremy Cook; Roxana Radu; Hui Sun; Gabriel Travis

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3764. doi:

ARVO Annual Meeting Abstract June 2013

LONG-TERM PROTECTION BY COMPLEMENT REGULATORY PROTEIN CRRY IN A MOUSE MODEL OF LIPOFUSCIN-MEDIATED RETINAL DEGENERATION

Shanta Sarfare; Anita Kim; Zhichun Jiang; Marcia Lloyd; Shannan Eddington; Samer Habib; Dean Bok; Steven Nusinowitz; Gabriel Travis; Roxana Radu

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2728. doi:

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Geographic Atrophy: Confocal Scanning Laser Ophthalmoscopy, Histology, and Inflammation in the Region of Expanding Lesions

Complement Dysregulation is Evidenced in iPSC-derived RPE Cells from Stargardt Disease patients

Reduced expression of “normal” ABCA4 alleles in iPS-derived RPE cells from Stargardt Disease patients

RGR opsin and RDH10 in Müller Cells Affect Light Dependent Synthesis of Chromophore Precursor for Cone Pigment Regeneration

Retinoid recycling is impaired in Stargardt iPSC-derived RPE

Complement C5 Inhibition as a Potential Treatment for Autosomal Recessive Stargardt Disease (STGD1): Design of a Clinical Trial Assessing a Novel Treatment and Primary Outcome Measure

Characterization of Stargardt iPSC-derived RPE cells

Localization of ABCA4 in the Retinal Pigment Epithelium and its implications for Stargardt Disease

Expression of ABCA4 in Retinal Pigment Epithelium cells and its implications for Stargardt disease

AAV-mediated delivery of ABCA4 to the photoreceptors of Abca4 -/- mice using an overlapping dual vector strategy

Liver x receptors (LXR) at the intersection of lipid metabolism and inflammation: implications for age-related macular degeneration (AMD)

Complement reactivity in Stargardt macular degeneration

Peropsin Effects Light-dependent Modulation of Retinyl Esters in the RPE

Elucidating the role of Retinal Pigment Epithelium (RPE)-specific ABCA4 in Stargardt disease

Monoallelic ABCA4 Mutations Appear Insufficient to Cause Retinopathy: A Quantitative Autofluorescence Study

Characterization of the Cfh-/-Abca4-/- mouse model

In Situ Localization of Complement Factor H Gene Expression in the Mouse Eye

Fundus Autofluorescence in the Abca4 −/− Mouse Model of Stargardt Disease—Correlation With Accumulation of A2E, Retinal Function, and Histology

Functional Characterization of Peropsin in the Retinal Pigment Epithelium

LONG-TERM PROTECTION BY COMPLEMENT REGULATORY PROTEIN CRRY IN A MOUSE MODEL OF LIPOFUSCIN-MEDIATED RETINAL DEGENERATION

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