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ARVO Annual Meeting Abstract July 2018

Genome-wide association analyses identify novel gene associated with central corneal thickness and keratoconus; The Nagahama Study

Yoshikatsu Hosoda; Masahiro Miyake; Chiea Chuen Khor; Yasuharu Tabara; Hideo Nakanishi; Akira Meguro; Ching-Yu Cheng; Seang-Mei Saw; Nobuhisa Mizuki; Ryo Yamada; Fumihiko Matsuda; Akitaka Tsujikawa; Kenji Yamashiro

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1819.

Glaucoma May 2017

Association of Glaucoma-Susceptible Genes to Regional Circumpapillary Retinal Nerve Fiber Layer Thickness and Visual Field Defects

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Munemitsu Yoshikawa; Hideo Nakanishi; Kenji Yamashiro; Masahiro Miyake; Tadamichi Akagi; Norimoto Gotoh; Hanako O. Ikeda; Kenji Suda; Hiroshi Yamada; Tomoko Hasegawa; Yuto Iida; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura; for the Nagahama Study Group
TAGS: genes, glaucoma, retinal nerve fiber layer, scotoma, visual field defects, single nucleotide polymorphism, open-angle glaucoma, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2510-2519. https://doi.org/10.1167/iovs.16-20797

Includes: Supplemental Content

Retina August 2015

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye

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Masahiro Miyake; Kenji Yamashiro; Hiroshi Tamura; Kyoko Kumagai; Masaaki Saito; Masako Sugahara-Kuroda; Munemitsu Yoshikawa; Maho Oishi; Yumiko Akagi-Kurashige; Isao Nakata; Hideo Nakanishi; Norimoto Gotoh; Akio Oishi; Fumihiko Matsuda; Ryo Yamada; Chiea-Chuen Khor; Yasuo Kurimoto; Tetsuju Sekiryu; Akitaka Tsujikawa; Nagahisa Yoshimura
TAGS: age-related macular degeneration, eye, genes, genetics, incidence, genetic risk, cohort studies, single nucleotide polymorphism, cultural formulation interview, disease susceptibility
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5353-5361. https://doi.org/10.1167/iovs.14-16020

Includes: Supplemental Content

Genetics November 2014

Comprehensive Replication of the Relationship Between Myopia-Related Genes and Refractive Errors in a Large Japanese Cohort

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Munemitsu Yoshikawa; Kenji Yamashiro; Masahiro Miyake; Maho Oishi; Yumiko Akagi-Kurashige; Kyoko Kumagai; Isao Nakata; Hideo Nakanishi; Akio Oishi; Norimoto Gotoh; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura; for the Nagahama Study Group
TAGS: cohort studies, genes, japanese, myopia, refractive errors, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7343-7354. https://doi.org/10.1167/iovs.14-15105

Includes: Supplemental Content

Retina March 2014

Three-Dimensional Optical Coherence Tomography Evaluation of Vascular Changes at Arteriovenous Crossings

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Kyoko Kumagai; Akitaka Tsujikawa; Yuki Muraoka; Yumiko Akagi-Kurashige; Tomoaki Murakami; Kazuaki Miyamoto; Ryo Yamada; Nagahisa Yoshimura
TAGS: diameter, fundus photography, optical coherence tomography, eye, hypertension, retinal vessels, compression
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1867-1875. https://doi.org/10.1167/iovs.13-13303

Includes: Multimedia, Supplemental Content

Genetics November 2013

Association Between ZIC2 , RASGRF1 , and SHISA6 Genes and High Myopia in Japanese Subjects

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Maho Oishi; Kenji Yamashiro; Masahiro Miyake; Yumiko Akagi-Kurashige; Kyoko Kumagai; Isao Nakata; Hideo Nakanishi; Munemitsu Yoshikawa; Akio Oishi; Norimoto Gotoh; Akitaka Tsujikawa; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: genes, japanese, myopia, ras protein specific guanine nucleotide releasing factor 1, single nucleotide polymorphism, choroidal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7492-7497. https://doi.org/10.1167/iovs.13-12825

Genetics September 2013

Association Between the Cholesteryl Ester Transfer Protein Gene and Polypoidal Choroidal Vasculopathy

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Isao Nakata; Kenji Yamashiro; Takahisa Kawaguchi; Norimoto Gotoh; Hideo Nakanishi; Yumiko Akagi-Kurashige; Masahiro Miyake; Akitaka Tsujikawa; Akio Oishi; Masaaki Saito; Tomohiro Iida; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: cholesterol ester transfer proteins, genes, vascular diseases, high density lipoprotein cholesterol
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):6068-6073. https://doi.org/10.1167/iovs.13-11605

ARVO Annual Meeting Abstract June 2013

Heritability Estimation of Axial Length and Refractive Error Explained by Genome-Wide Single Nucleotide Polymorphisms

Masahiro Miyake; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Yumiko Akagi-Kurashige; Kyoko Kumagai; Akitaka Tsujikawa; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura; Nagahama Study Group

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1734.

Retina April 2012

Vascular Endothelial Growth Factor Gene Polymorphisms and Choroidal Neovascularization in Highly Myopic Eyes

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Yumiko Akagi-Kurashige; Kyoko Kumagai; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Masahiro Miyake; Akitaka Tsujikawa; Muka Moriyama; Kyoko Ohno-Matsui; Manabu Mochizuki; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: choroidal neovascularization, eye, genes, polymorphism, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2012; 53(4):2349-2353. https://doi.org/10.1167/iovs.11-9405

Retina February 2012

Significance of C2 / CFB Variants in Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in a Japanese Population

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Isao Nakata; Kenji Yamashiro; Ryo Yamada; Norimoto Gotoh; Hideo Nakanishi; Hisako Hayashi; Yumiko Akagi-Kurashige; Akitaka Tsujikawa; Atsushi Otani; Masaaki Saito; Tomohiro Iida; Akio Oishi; Keitaro Matsuo; Kazuo Tajima; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: age-related macular degeneration, japanese, vascular diseases, cohort studies, cataract
Invest. Ophthalmol. Vis. Sci.. 2012; 53(2):794-798. https://doi.org/10.1167/iovs.11-8468

Retina November 2011

Association of Elastin Gene Polymorphism to Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy

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Kenji Yamashiro; Keisuke Mori; Isao Nakata; Takashi Tsuchihashi; Kuniko Horie-Inoue; Hideo Nakanishi; Akitaka Tsujikawa; Masaaki Saito; Tomohiro Iida; Ryo Yamada; Fumihiko Matsuda; Satoshi Inoue; Takuya Awata; Shin Yoneya; Nagahisa Yoshimura
TAGS: age-related macular degeneration, eln gene, polymorphism, vascular diseases, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2011; 52(12):8780-8784. https://doi.org/10.1167/iovs.11-8205

Genetics June 2011

Association of 15q14 and 15q25 with High Myopia in Japanese

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Hisako Hayashi; Kenji Yamashiro; Hideo Nakanishi; Isao Nakata; Yumiko Kurashige; Akitaka Tsujikawa; Muka Moriyama; Kyoko Ohno-Matsui; Manabu Mochizuki; Mineo Ozaki; Ryo Yamada; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: japanese, myopia, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2011; 52(7):4853-4858. https://doi.org/10.1167/iovs.11-7311

Biochemistry and Molecular Biology December 2010

Joint Effect of Cigarette Smoking and CFH and LOC387715/HTRA1 Polymorphisms on Polypoidal Choroidal Vasculopathy

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Hideo Nakanishi; Kenji Yamashiro; Ryo Yamada; Norimoto Gotoh; Hisako Hayashi; Isao Nakata; Masaaki Saito; Tomohiro Iida; Akio Oishi; Yasuo Kurimoto; Keitaro Matsuo; Kazuo Tajima; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: htra1 gene, polymorphism, smoking, vascular diseases, cfh y402h
Invest. Ophthalmol. Vis. Sci.. 2010; 51(12):6183-6187. https://doi.org/10.1167/iovs.09-4948

Retina November 2010

CFH and ARMS2 Variations in Age-Related Macular Degeneration, Polypoidal Choroidal Vasculopathy, and Retinal Angiomatous Proliferation

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Hisako Hayashi; Kenji Yamashiro; Norimoto Gotoh; Hideo Nakanishi; Isao Nakata; Akitaka Tsujikawa; Atsushi Otani; Masaaki Saito; Tomohiro Iida; Keitaro Matsuo; Kazuo Tajima; Ryo Yamada; Nagahisa Yoshimura
TAGS: age-related macular degeneration, polymorphism, vascular diseases, alleles, cfh y402h, exudative age-related macular degeneration, genotype
Invest. Ophthalmol. Vis. Sci.. 2010; 51(11):5914-5919. https://doi.org/10.1167/iovs.10-5554

Biochemistry and Molecular Biology September 2010

Single-Nucleotide Polymorphisms in the Promoter Region of Matrix Metalloproteinase-1, -2, and -3 in Japanese with High Myopia

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Hideo Nakanishi; Hisako Hayashi; Ryo Yamada; Kenji Yamashiro; Isao Nakata; Noriaki Shimada; Kyoko Ohno-Matsui; Manabu Mochizuki; Mineo Ozaki; Shin Yoshitake; Shoji Kuriyama; Masaaki Saito; Tomohiro Iida; Keitaro Matsuo; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: interstitial collagenase, japanese, myopia, promoter regions (genetics), single nucleotide polymorphism, gelatinase a, stromelysin 1
Invest. Ophthalmol. Vis. Sci.. 2010; 51(9):4432-4436. https://doi.org/10.1167/iovs.09-4871

Biochemistry and Molecular Biology February 2009

Absence of Association between COL1A1 Polymorphisms and High Myopia in the Japanese Population

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Hideo Nakanishi; Ryo Yamada; Norimoto Gotoh; Hisako Hayashi; Atsushi Otani; Akitaka Tsujikawa; Kenji Yamashiro; Noriaki Shimada; Kyoko Ohno-Matsui; Manabu Mochizuki; Masaaki Saito; Kuniharu Saito; Tomohiro Iida; Fumihiko Matsuda; Nagahisa Yoshimura
TAGS: japanese, myopia, polymorphism, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2009; 50(2):544-550. https://doi.org/10.1167/iovs.08-2425

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Genome-wide association analyses identify novel gene associated with central corneal thickness and keratoconus; The Nagahama Study

Association of Glaucoma-Susceptible Genes to Regional Circumpapillary Retinal Nerve Fiber Layer Thickness and Visual Field Defects

The Contribution of Genetic Architecture to the 10-Year Incidence of Age-Related Macular Degeneration in the Fellow Eye

Comprehensive Replication of the Relationship Between Myopia-Related Genes and Refractive Errors in a Large Japanese Cohort

Three-Dimensional Optical Coherence Tomography Evaluation of Vascular Changes at Arteriovenous Crossings

Association Between ZIC2 , RASGRF1 , and SHISA6 Genes and High Myopia in Japanese Subjects

Association Between the Cholesteryl Ester Transfer Protein Gene and Polypoidal Choroidal Vasculopathy

Heritability Estimation of Axial Length and Refractive Error Explained by Genome-Wide Single Nucleotide Polymorphisms

Vascular Endothelial Growth Factor Gene Polymorphisms and Choroidal Neovascularization in Highly Myopic Eyes

Significance of C2 / CFB Variants in Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in a Japanese Population

Association of Elastin Gene Polymorphism to Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy

Association of 15q14 and 15q25 with High Myopia in Japanese

Joint Effect of Cigarette Smoking and CFH and LOC387715/HTRA1 Polymorphisms on Polypoidal Choroidal Vasculopathy

CFH and ARMS2 Variations in Age-Related Macular Degeneration, Polypoidal Choroidal Vasculopathy, and Retinal Angiomatous Proliferation

Single-Nucleotide Polymorphisms in the Promoter Region of Matrix Metalloproteinase-1, -2, and -3 in Japanese with High Myopia

Absence of Association between COL1A1 Polymorphisms and High Myopia in the Japanese Population

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