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Cornea & External Disease August 2024

Effect of Topical Losartan in the Treatment of Established Corneal Fibrosis in Rabbits

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Valeria Villabona Martinez; Barbara Araujo Lima Dutra; Marcony R. Santhiago; Steven E. Wilson
TAGS: cornea, fibrosis, losartan, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2024; 13(8):22. https://doi.org/10.1167/tvst.13.8.22

ARVO Annual Meeting Abstract June 2024

TGF beta-3 localization in rabbit corneas with spontaneous persistent epithelial defects after Photorefractive keratectomy (PRK)

Valeria Villabona Martinez; Barbara Dutra; Lycia Pedral Sampaio; Thomas M Shiju; Santhiago Marcony; Steven E Wilson

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):504.

Cornea & External Disease September 2023

Topical Losartan Decreases Myofibroblast Generation But Not Corneal Opacity After Surface Blast-Simulating Irregular PTK in Rabbits

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Lycia Pedral Sampaio; Valeria Villabona-Martinez; Thomas Michael Shiju; Marcony R. Santhiago; Steven E. Wilson
TAGS: blast injuries, cornea, corneal opacity, losartan, myofibroblasts, oryctolagus cuniculus, basic local alignment search tool, collagen type iv
Trans. Vis. Sci. Tech.. 2023; 12(9):20. https://doi.org/10.1167/tvst.12.9.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

TGF beta-3, corneal myofibroblast differentiation, and development of corneal fibrosis after photorefractive keratectomy in rabbits

Shiju Thomas Michael; Lycia Pedral Sampaio; Guilherme Hilgert; Steven E Wilson

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4593.

ARVO Annual Meeting Abstract June 2023

Standardization of corneal alkali burn methodology in rabbits

Valeria Villabona Martinez; Lycia Pedral Sampaio; Shiju Thomas Michael; Steven E Wilson

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4585.

ARVO Annual Meeting Abstract June 2023

Cell biology of spontaneous persistent epithelial defects after photorefractive keratectomy in rabbits

Steven E Wilson; Lycia Pedral Sampaio; Valeria Villabona-Martinez; Shiju Thomas Michael; Guilherme Hilgert; Marcony R Santhiago

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4584.

ARVO Annual Meeting Abstract June 2023

Topical losartan inhibition of myofibroblast generation and scar formation after fibrotic irregular phototherapeutic keratectomy in rabbits

Lycia Pedral Sampaio; Valeria Villabona-Martinez; Shiju Thomas Michael; Steven E Wilson

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4596.

Cornea & External Disease May 2023

Cell Biology of Spontaneous Persistent Epithelial Defects After Photorefractive Keratectomy in Rabbits

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Lycia Pedral Sampaio; Valeria Villabona Martinez; Thomas Michael Shiju; Guilherme S. L. Hilgert; Marcony R. Santhiago; Steven E. Wilson
TAGS: cellular biology, cornea, epithelium, keratectomy, oryctolagus cuniculus, persistence, surgical procedures, operative, myofibroblasts, collagen type iv, vimentin
Trans. Vis. Sci. Tech.. 2023; 12(5):15. https://doi.org/10.1167/tvst.12.5.15

Includes: Supplemental Content

Cornea & External Disease July 2022

Topical Losartan and Corticosteroid Additively Inhibit Corneal Stromal Myofibroblast Generation and Scarring Fibrosis After Alkali Burn Injury

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Lycia Pedral Sampaio; Guilherme S. L. Hilgert; Thomas Michael Shiju; Marcony R. Santhiago; Steven E. Wilson
TAGS: adrenal corticosteroids, alkalies, burns, cicatrix, cornea, fibrosis, glucocorticoids, losartan, mineralocorticoids, myofibroblasts
Trans. Vis. Sci. Tech.. 2022; 11(7):9. https://doi.org/10.1167/tvst.11.7.9

Includes: Supplemental Content

Review January 2022

Corneal Opacity: Cell Biological Determinants of the Transition From Transparency to Transient Haze to Scarring Fibrosis, and Resolution, After Injury

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Steven E. Wilson; Lycia Pedral Sampaio; Thomas Michael Shiju; Guilherme S. L. Hilgert; Rodrigo Carlos de Oliveira
TAGS: cicatrix, cornea, corneal injuries, corneal opacity, fibrosis, transparency, wounds and injuries, extracellular matrix, fibroblasts, myofibroblasts
Invest. Ophthalmol. Vis. Sci.. 2022; 63(1):22. https://doi.org/10.1167/iovs.63.1.22

ARVO Annual Meeting Abstract June 2021

Perlecan-associated defective epithelial basement membrane regeneration in rabbit corneas after fibrosis-inducing epithelial-stromal injury

Rodrigo Carlos De Oliveira; George Tye; Lycia Sampaio; Thomas Michael Shiju; Marcony R Santhiago; JodiRae DeDreu; A Sue Menko; Steven E Wilson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):931.

ARVO Annual Meeting Abstract June 2021

Assembly of epithelial basement membrane (EBM) in vitro in a 3D organotypic cornea model

Shiju Thomas; Rodrigo Carlos de Oliveira; Lycia Pedral Sampaio; Guilherme Simões Luz Hilgert; Steven E Wilson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):933.

Review April 2021

Interleukin-1 and Transforming Growth Factor Beta: Commonly Opposing, but Sometimes Supporting, Master Regulators of the Corneal Wound Healing Response to Injury

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Steven E. Wilson
TAGS: cornea, fibroblasts, interleukin-1, wounds and injuries, myofibroblasts, wound healing, keratocytes, transforming growth factor beta, epithelium
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):8. https://doi.org/10.1167/iovs.62.4.8

Articles March 2020

The Efficacy of Topical HGF on Corneal Fibrosis and Epithelial Healing after Scar-Producing PRK Injury in Rabbits

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Rodrigo Carlos de Oliveira; Sofia Murillo; Paramananda Saikia; Steven E. Wilson
TAGS: cicatrix, cornea, epithelium, fibrosis, oryctolagus cuniculus, wound healing, wounds and injuries, myofibroblasts, corneal opacity, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2020; 9(4):29. https://doi.org/10.1167/tvst.9.4.29

Review February 2020

Fibrocytes, Wound Healing, and Corneal Fibrosis

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Rodrigo Carlos de Oliveira; Steven E. Wilson
TAGS: cicatrix, cornea, fibrosis, wound healing, wounds and injuries, myofibroblasts, body tissue
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):28. https://doi.org/10.1167/iovs.61.2.28

ARVO Annual Meeting Abstract July 2019

Descemet’s basement membrane modulation of corneal fibrosis

Steven E Wilson; Carla S Medeiros; Paramananda Saikia; Rodrigo Carlos de Oliveira; Luciana Lassance; Marcony R Santhiago

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5251.

ARVO Annual Meeting Abstract July 2019

Proteome of keratocyte-derived versus bone marrow-derived myofibroblasts. Are they different?

Paramananda Saikia; Madison Juszczak; Luciana L Dibbin; Rodrigo Carlos Oliveira; Carla S Medeiros; Belinda Willard; Jang Geeng-Fu; Jack S Crabb; John W Crabb; Steven E Wilson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5254.

ARVO Annual Meeting Abstract July 2019

Laminins, and early corneal epithelial basement membrane (EBM) regeneration

Rodrigo Carlos De Oliveira; Paramananda Saikia; Steven E Wilson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4663.

Cornea March 2019

Descemet's Membrane Modulation of Posterior Corneal Fibrosis

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Carla S. Medeiros; Paramananda Saikia; Rodrigo Carlos de Oliveira; Luciana Lassance; Marcony R. Santhiago; Steven E. Wilson
TAGS: cicatrix, cornea, descemet's membrane, endothelium, fibrosis, wounds and injuries, myofibroblasts, antibodies, in situ nick-end labeling
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1010-1020. https://doi.org/10.1167/iovs.18-26451

Includes: Supplemental Content

Cornea November 2018

IL-1 and TGF-β Modulation of Epithelial Basement Membrane Components Perlecan and Nidogen Production by Corneal Stromal Cells

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Paramananda Saikia; Shanmugapriya Thangavadivel; Carla S. Medeiros; Luciana Lassance; Rodrigo Carlos de Oliveira; Steven E. Wilson
TAGS: cornea, epithelium, interleukin-1, keratocytes, nidogen, stromal cells, basement membrane, proteins, myofibroblasts, western blotting
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5589-5598. https://doi.org/10.1167/iovs.18-25202

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Effect of Topical Losartan in the Treatment of Established Corneal Fibrosis in Rabbits

TGF beta-3 localization in rabbit corneas with spontaneous persistent epithelial defects after Photorefractive keratectomy (PRK)

Topical Losartan Decreases Myofibroblast Generation But Not Corneal Opacity After Surface Blast-Simulating Irregular PTK in Rabbits

TGF beta-3, corneal myofibroblast differentiation, and development of corneal fibrosis after photorefractive keratectomy in rabbits

Standardization of corneal alkali burn methodology in rabbits

Cell biology of spontaneous persistent epithelial defects after photorefractive keratectomy in rabbits

Topical losartan inhibition of myofibroblast generation and scar formation after fibrotic irregular phototherapeutic keratectomy in rabbits

Cell Biology of Spontaneous Persistent Epithelial Defects After Photorefractive Keratectomy in Rabbits

Topical Losartan and Corticosteroid Additively Inhibit Corneal Stromal Myofibroblast Generation and Scarring Fibrosis After Alkali Burn Injury

Corneal Opacity: Cell Biological Determinants of the Transition From Transparency to Transient Haze to Scarring Fibrosis, and Resolution, After Injury

Perlecan-associated defective epithelial basement membrane regeneration in rabbit corneas after fibrosis-inducing epithelial-stromal injury

Assembly of epithelial basement membrane (EBM) in vitro in a 3D organotypic cornea model

Interleukin-1 and Transforming Growth Factor Beta: Commonly Opposing, but Sometimes Supporting, Master Regulators of the Corneal Wound Healing Response to Injury

The Efficacy of Topical HGF on Corneal Fibrosis and Epithelial Healing after Scar-Producing PRK Injury in Rabbits

Fibrocytes, Wound Healing, and Corneal Fibrosis

Descemet’s basement membrane modulation of corneal fibrosis

Proteome of keratocyte-derived versus bone marrow-derived myofibroblasts. Are they different?

Laminins, and early corneal epithelial basement membrane (EBM) regeneration

Descemet's Membrane Modulation of Posterior Corneal Fibrosis

IL-1 and TGF-β Modulation of Epithelial Basement Membrane Components Perlecan and Nidogen Production by Corneal Stromal Cells

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