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ARVO Annual Meeting Abstract June 2024

Bioanalytical solutions and immunogenicity challenges of species-matched antibodies in preclinical studies while investigating protein-loaded long-acting intravitreal delivery technologies

Kelly Loyet; Hilda Hernandez-Barry; Kathy Barrett; Mauricio Maia; Yanqiu Liu; Hanine Rafidi; Danielle Mandikian; Andy Boswell; Joyce Chan; Laetitia Comps-Agrar; Susan Ritger Crowell; Steven Laing; Amin Famili; Whitney Shatz-Binder; Devin Tesar; Robert Kelley

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3785.

Articles November 2019

Influence of Charge, Hydrophobicity, and Size on Vitreous Pharmacokinetics of Large Molecules

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Susan R. Crowell; Kathryn Wang; Amin Famili; Whitney Shatz; Kelly M. Loyet; Vincent Chang; Yanqiu Liu; Saileta Prabhu; Amrita V. Kamath; Robert F. Kelley
TAGS: hydrophobicity, molecule, ranibizumab, vitreous body, pharmacokinetics, oryctolagus cuniculus
Trans. Vis. Sci. Tech.. 2019; 8(6):1. https://doi.org/10.1167/tvst.8.6.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Utility of quantitative autoradiography for drug pharmacology and ocular tissue distribution in New Zealand White Rabbits

Amy Shelton; Susan Crowell; Hanine Anezinos; Danielle Mandikian; Phillip Chu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6104.

ARVO Annual Meeting Abstract July 2018

Retinal toxicity in rabbits administered intravitreal TSG-6-rabbit FAb fusion proteins

Steven Thomas Laing; Devin Tesar; Susan Crowell; Julia Gray; Kelly Loyet; Roxanne Andaya; Aija McKenzie; Florence Lorget; Bob Kelley

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):216.

ARVO Annual Meeting Abstract July 2018

Hyaluronic acid conjugation significantly extends the vitreal half-life of antibody fragments

Susan Crowell; Amin Famili; C. Andrew Boswell; Joyce Chan; Julia Gray; Kelly Loyet; Laetitia Comps-Agrar; Amrita kamath; Karthikan Rajagopal

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):235.

ARVO Annual Meeting Abstract July 2018

Implementation of bioanalytical methods to quantify anti-VEGF-LAD (long acting delivery) Fabs in ocular matrices

Laetitia Comps-Agrar; Hilda Hernández-Barry; Joyce Chan; Keyang Xu; Luna Liu; Susan Crowell; Bob Kelley; Devin Tesar; Kelly Loyet

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):239.

ARVO Annual Meeting Abstract July 2018

Ocular and Systemic Pharmacokinetics of a PEGylated-anti-Factor D Fab Multimer in Cynomolgous Monkeys

Daniela Bumbaca Yadav; Whitney B Shatz; danielle mandikian; C. Andrew Boswell; Aija McKenzie; Daniel Sheinson; Hong Liu; Isabel Figueroa; Bob Kelley; Devin Tesar; Michelle Dion; Amrita kamath; Florence Lorget; Susan Crowell

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):242.

ARVO Annual Meeting Abstract June 2017

Influence of charge, hydrophobicity, and hydrodynamic radius on vitreous pharmacokinetics of large molecules

Susan Crowell; Kathryn Wang; Leslie Dickmann; C. Andrew Boswell; Daniela Bumbaca Yadav; Mauricio Maia; Whitney Shatz; Amin Famili; Karthik Rajagopal; Devin Tesar; Robert F. Kelley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3600.

ARVO Annual Meeting Abstract June 2013

Circulating Mesenchymal Progenitor Cells in Patients with Neovascular Age-Related Macular Degeneration

Scott Cousins; Priyatham Mettu; Tiffany Pridgen; Sara Crowell; M. Grazia Spiga

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3663.

ARVO Annual Meeting Abstract March 2012

ABCA4 Genotypic Diversity And Phenotypic Correlates In Stargardt Disease

Virginia M. Utz; Aimee V. Chappelow; Susan Crowe; Gayle J. Pauer; Stephanie A. Hagstrom; Elias I. Traboulsi

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4557.

ARVO Annual Meeting Abstract March 2012

High-speed Indocyanine Green Angiography In Age Related Macular Degeneration With Fibrovascular Pigment Epithelial Detachments

Neha P. Serrano; Jeremy Shaw; Priyatham S. Mettu; Eleonora M. Lad; Sara Crowell; Scott W. Cousins

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1151.

ARVO Annual Meeting Abstract March 2012

Lesion Morphology on Indocyanine Green Angiography in Age-Related Macular Degeneration with Classic Choroidal Neovascular Membrane: Implications for Response to anti-VEGF Treatment

Eleonora M. Lad; Lili Grunwald; Priyatham S. Mettu; Neha P. Serrano; Sara Crowell; Scott W. Cousins

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5161.

ARVO Annual Meeting Abstract March 2012

Neovascular Morphology on ICG Angiography Predicts Response to Anti-VEGF Therapy in Eyes with Serous Pigment Epithelial Detachments and Age-Related Macular Degeneration

Priyatham S. Mettu; Sara Crowell; Jeremy Shaw; Lili Grunwald; Eleonora M. Lad; Neha Serrano; Scott W. Cousins

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2654.

ARVO Annual Meeting Abstract March 2012

The Relationship Between Trust, Race, And Glaucoma-related Blindness

Kelly W. Muir; Brian Alder; Sara K. Crowell; Sandra S. Stinnett; Anitra Thomas; Paul P. Lee

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4491.

ARVO Annual Meeting Abstract April 2011

Dietary Omega-3 Fatty Acids and Inflammation in a Mouse Model of Laser-induced Choroidal Neovascularization

Matthew W. Hollar; Diego Espinosa-Heidmann; Peter Saloupis; Askia Dunnon; Peng Hu; Tiffany Pridgen; Larry Koreen; Sara Crowell; Scott W. Cousins

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):945.

ARVO Annual Meeting Abstract May 2007

The Value of Central Corneal Curvature and Central Corneal Thickness in the Clinical Diagnosis of Marfan Syndrome

J. M. Heur; B. Costin; S. Crowe; A. Younoszai; R. A. Grimm; I. A. Schafer; B. A. Clark; L. Svensson; E. I. Traboulsi

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):1327.

ARVO Annual Meeting Abstract May 2007

CNGA3 Mutations in Two United Arab Emirates (UAE) Families With Achromatopsia

E. I. Traboulsi; S. Crowe; S. Kohl

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):3700.

ARVO Annual Meeting Abstract May 2005

Adjustable Globe and Muscle Technique for Strabismus Repair in Thyroid Eye Disease

A.J. Dal Canto; S. Crowe; J.D. Perry; E. Traboulsi

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):2963.

ARVO Annual Meeting Abstract May 2005

Study of the RAX Gene in Patients With Microphthalmia/Anophthalmia/Coloboma

N. London; P. Kessler; B. Williams; G. Pauer; S. Crowe; S. Hagstrom; E.I. Traboulsi

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):1837.

ARVO Annual Meeting Abstract May 2004

Short–Term Complications of Cataract Extraction with or without Intraocular Lens Implantation in the First Two Years of Life

E.I. Traboulsi; S. Crowe; D. Huang

Invest. Ophthalmol. Vis. Sci.. 2004; 45(13):324.

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Bioanalytical solutions and immunogenicity challenges of species-matched antibodies in preclinical studies while investigating protein-loaded long-acting intravitreal delivery technologies

Influence of Charge, Hydrophobicity, and Size on Vitreous Pharmacokinetics of Large Molecules

Utility of quantitative autoradiography for drug pharmacology and ocular tissue distribution in New Zealand White Rabbits

Retinal toxicity in rabbits administered intravitreal TSG-6-rabbit FAb fusion proteins

Hyaluronic acid conjugation significantly extends the vitreal half-life of antibody fragments

Implementation of bioanalytical methods to quantify anti-VEGF-LAD (long acting delivery) Fabs in ocular matrices

Ocular and Systemic Pharmacokinetics of a PEGylated-anti-Factor D Fab Multimer in Cynomolgous Monkeys

Influence of charge, hydrophobicity, and hydrodynamic radius on vitreous pharmacokinetics of large molecules

Circulating Mesenchymal Progenitor Cells in Patients with Neovascular Age-Related Macular Degeneration

ABCA4 Genotypic Diversity And Phenotypic Correlates In Stargardt Disease

High-speed Indocyanine Green Angiography In Age Related Macular Degeneration With Fibrovascular Pigment Epithelial Detachments

Lesion Morphology on Indocyanine Green Angiography in Age-Related Macular Degeneration with Classic Choroidal Neovascular Membrane: Implications for Response to anti-VEGF Treatment

Neovascular Morphology on ICG Angiography Predicts Response to Anti-VEGF Therapy in Eyes with Serous Pigment Epithelial Detachments and Age-Related Macular Degeneration

The Relationship Between Trust, Race, And Glaucoma-related Blindness

Dietary Omega-3 Fatty Acids and Inflammation in a Mouse Model of Laser-induced Choroidal Neovascularization

The Value of Central Corneal Curvature and Central Corneal Thickness in the Clinical Diagnosis of Marfan Syndrome

CNGA3 Mutations in Two United Arab Emirates (UAE) Families With Achromatopsia

Adjustable Globe and Muscle Technique for Strabismus Repair in Thyroid Eye Disease

Study of the RAX Gene in Patients With Microphthalmia/Anophthalmia/Coloboma

Short–Term Complications of Cataract Extraction with or without Intraocular Lens Implantation in the First Two Years of Life

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