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Cornea November 2024

Mechanisms Regulating Mitochondrial Transfer in Human Corneal Epithelial Cells

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Sonali Pal-Ghosh; Beverly A. Karpinski; Himani Datta-Majumdar; Soneha Datta; Shelly Dimri; Jordan Hally; Hugo Wehmeyer; Mary Ann Stepp
TAGS: mitochondria, mitochondrial donation, phagocytosis, corneal epithelial cells, neurons, cell adhesion
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):10. https://doi.org/10.1167/iovs.65.13.10

Includes: Supplemental Content

Cornea October 2024

ROCK Inhibitor Enhances Neurite Outgrowth In Vitro and Corneal Sensory Nerve Reinnervation In Vivo

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Beverly A. Karpinski; Sonali Pal-Ghosh; Himani Datta-Majumdar; Shelly Dimri; Soneha Datta; Mary Ann Stepp
TAGS: axon, cornea, mice, neuronal outgrowth, neurons, reinnervation, sensory nerves, wounds and injuries, debridement, integrins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):31. https://doi.org/10.1167/iovs.65.12.31

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Stimulator of interferon genes (STING) as a therapeutic target for atrophic age-related macular degeneration

Pooja Gautam; Sayan Ghosh; Victoria Koontz; Sridhar Bammidi; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):759.

ARVO Annual Meeting Abstract June 2024

Monoclonal Antibody Development for Lipocalin-2 Neutralization in Atrophic AMD

Mihir Nemani; Emma Mahally; Sayan Ghosh; Victoria Koontz; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):752.

ARVO Annual Meeting Abstract June 2024

Role of IL-17A in driving inflammatory responses in progression of dry age-related macular degeneration

Sayan Ghosh; Victoria Koontz; Sridhar Bammidi; Pooja Gautam; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):737.

ARVO Annual Meeting Abstract June 2024

Dysregulated natural killer cells mediate RPE dysfunction in early Age-Related Macular Degeneration

Archana Padmanabhan Nair; Sayan Ghosh; Praveen Machiraju; Swaminathan Sethu; Debasish Sinha; Arkasubhra Ghosh

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):570.

ARVO Annual Meeting Abstract June 2024

The influence of gut microbiome on inflammatory changes in the ocular environment is triggered by the peripheral immune system

Victoria Koontz; Sayan Ghosh; Sridhar Bammidi; Pooja Gautam; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1685.

ARVO Annual Meeting Abstract June 2024

Linking mitochondrial dysfunction to inflammation during the progression of atrophic age-related macular degeneration

Shruti Dhar; Victoria Koontz; Sridhar Bammidi; Mihir Nemani; Pooja Gautam; Stacey L Hose; Debasish Sinha; Sayan Ghosh

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2566.

ARVO Annual Meeting Abstract June 2024

Elevated mTORC1 and mTORC2 signaling in the retinal pigmented epithelium alters glucose metabolism, leading to a pathology resembling age-related macular degeneration

Sridhar Bammidi; Olivia Chowdhury; Sayan Ghosh; Victoria Koontz; Mihir Nemani; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2103.

ARVO Annual Meeting Abstract June 2024

Prolonged ECM stiffening induces a glaucoma-like phenotype in trabecular meshwork cells through mechanical memory retention

Rajanya Ghosh; Suhani Patel; Izzy Salama; Michael P Geiss; Souvik Ghosh; Kate E Keller; Preethi S Ganapathy; Samuel Herberg

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6463.

ARVO Annual Meeting Abstract June 2024

MMC and Rock Inhibitor (RI) Impact Mitochondrial Activation and Cell Velocity in Human Corneal Epithelial Cells (HCLEs): Implications for Cell Adhesion and Senescence During Wound Healing

Himani Datta Majumdar; Beverly Karpinski; Soneha Datta; Shelly Dimri; Sonali Pal-Ghosh; Mary Ann Stepp

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):64.

ARVO Annual Meeting Abstract June 2024

Trephine injury of mouse intraepithelial corneal nerves (ICNs) increases axonal mitochondrial transport to nerve terminals and enhances transfer of metabolically active mitochondria to corneal epithelial cells

Mary Ann Stepp; Himani Datta-Majumdar; Beverly Karpinski; Wentao Liang; Jian-Xing (Jay) Ma; Sonali Pal-Ghosh

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):35.

ARVO Annual Meeting Abstract June 2024

Distinct Immunoregulatory Properties of Immune Cells that Associate with the Lens Capsule Surface in Response to Different Eye Pathologies

Phuong Le; Sonali Pal-Ghosh; Mary J Mattapallil; Rachel R Caspi; Mary Ann Stepp; A Sue Menko

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1110.

ARVO Annual Meeting Abstract June 2024

Atypical Vascular Inflammation in Retinal Vasculopathies: Targeting p38 Signaling

Neil Grimsey; Sneha S Ghosh; Sanjana Gattineni; Heike Kroeger; S. Priya Narayanan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):272.

Biochemistry and Molecular Biology May 2024

Age-Related Differences in the Mouse Corneal Epithelial Transcriptome and Their Impact on Corneal Wound Healing

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Anmar Abu-Romman; Kaitlin K. Scholand; Gowthaman Govindarajan; Zhiyuan Yu; Sonali Pal-Ghosh; Mary A. Stepp; Cintia S. de Paiva
TAGS: cornea, debridement, epithelium, mice, wound healing, wounds and injuries, corneal epithelium
Invest. Ophthalmol. Vis. Sci.. 2024; 65(5):21. https://doi.org/10.1167/iovs.65.5.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Akt2 signaling in RPE contributes to retinal fibrosis in DR

Haitao Liu; Vishnu Maddipatla; Sayan Ghosh; Victoria Koontz; Stacey L Hose; J. Samuel Zigler Jr.; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):498.

ARVO Annual Meeting Abstract June 2023

SIRT5/Akt2 signaling axis regulates TFEB activity and autophagy in the RPE cells: Implications in dry age-related macular degeneration

Sayan Ghosh; Victoria Koontz; Mihir Nemani; Olivia Chowdhury; Haitao Liu; Stacey L Hose; J. Samuel Zigler Jr.; James T Handa; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5389.

ARVO Annual Meeting Abstract June 2023

Atypical p38 Signaling in Retinal Vasculopathies

Sneha Srikumar Ghosh; Morgan Roos; Jeremy Burton; Priya Narayanan; Neil Grimsey

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2092.

ARVO Annual Meeting Abstract June 2023

Pharmacological modulation of autophagy and its therapeutic potential in the pathogenesis of pterygium disease

Nallathambi Jeyabalan; Naveen kumar; Shivapriya Shivakumar; Ramya Rompicherla; Nandini C; Sharon D 'Souza; ROHIT SHETTY; Arka subhra Ghosh

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2933.

ARVO Annual Meeting Abstract June 2023

Stargardt families from South India demonstrate unique phenotypes and novel genotypes

Poornachandra B; Sharath Babu; Andrew Peterson; Sekar Seshagiri; Arka subhra Ghosh

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2794.

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Mechanisms Regulating Mitochondrial Transfer in Human Corneal Epithelial Cells

ROCK Inhibitor Enhances Neurite Outgrowth In Vitro and Corneal Sensory Nerve Reinnervation In Vivo

Stimulator of interferon genes (STING) as a therapeutic target for atrophic age-related macular degeneration

Monoclonal Antibody Development for Lipocalin-2 Neutralization in Atrophic AMD

Role of IL-17A in driving inflammatory responses in progression of dry age-related macular degeneration

Dysregulated natural killer cells mediate RPE dysfunction in early Age-Related Macular Degeneration

The influence of gut microbiome on inflammatory changes in the ocular environment is triggered by the peripheral immune system

Linking mitochondrial dysfunction to inflammation during the progression of atrophic age-related macular degeneration

Elevated mTORC1 and mTORC2 signaling in the retinal pigmented epithelium alters glucose metabolism, leading to a pathology resembling age-related macular degeneration

Prolonged ECM stiffening induces a glaucoma-like phenotype in trabecular meshwork cells through mechanical memory retention

MMC and Rock Inhibitor (RI) Impact Mitochondrial Activation and Cell Velocity in Human Corneal Epithelial Cells (HCLEs): Implications for Cell Adhesion and Senescence During Wound Healing

Trephine injury of mouse intraepithelial corneal nerves (ICNs) increases axonal mitochondrial transport to nerve terminals and enhances transfer of metabolically active mitochondria to corneal epithelial cells

Distinct Immunoregulatory Properties of Immune Cells that Associate with the Lens Capsule Surface in Response to Different Eye Pathologies

Atypical Vascular Inflammation in Retinal Vasculopathies: Targeting p38 Signaling

Age-Related Differences in the Mouse Corneal Epithelial Transcriptome and Their Impact on Corneal Wound Healing

Akt2 signaling in RPE contributes to retinal fibrosis in DR

SIRT5/Akt2 signaling axis regulates TFEB activity and autophagy in the RPE cells: Implications in dry age-related macular degeneration

Atypical p38 Signaling in Retinal Vasculopathies

Pharmacological modulation of autophagy and its therapeutic potential in the pathogenesis of pterygium disease

Stargardt families from South India demonstrate unique phenotypes and novel genotypes

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