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Cornea February 2025

Identification of Wnt-5a Receptors Important in Diabetic and Non-Diabetic Corneal Epithelial Wound Healing

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Ruchi Shah; Cynthia Amador; Adam J. Poe; Tanya M. Spektor; Priyanka Bhandary; Yizhou Wang; Zhiping Paul Wang; Daniel J. Weisenberger; Vanessa F. Borges; Onkar B. Sawant; Ezra Maguen; Pedram Hamrah; Andrei A. Kramerov; Mehrnoosh Saghizadeh; Alexander V. Ljubimov
TAGS: cornea, diabetes mellitus, receptors, wnt, wnt-5a protein, wound healing, epithelium, receptor tyrosine kinase-like orphan receptor 2
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):64. https://doi.org/10.1167/iovs.66.2.64

Includes: Supplemental Content

Retina December 2024

Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy

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Dhavamani Sugasini; Poorna C. R. Yalagala; Jason C. Park; Guangying Ma; Zeenat Farooq; Basma Baccouche; Onkar B. Sawant; J. Jason McAnany; Xincheng Yao; Andrius Kazlauskas; Brian T. Layden; Papasani V. Subbaiah
TAGS: diabetes mellitus, diabetic retinopathy, fatty acids, mice, retina, docosahexaenoic acids, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):39. https://doi.org/10.1167/iovs.65.14.39

Includes: Supplemental Content

Artificial Intelligence August 2024

Automatic Determination of Endothelial Cell Density From Donor Cornea Endothelial Cell Images

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Beth Ann M. Benetz; Ved S. Shivade; Naomi M. Joseph; Nathan J. Romig; John C. McCormick; Jiawei Chen; Michael S. Titus; Onkar B. Sawant; Jameson M. Clover; Nathan Yoganathan; Harry J. Menegay; Robert C. O'Brien; David L. Wilson; Jonathan H. Lass
TAGS: cornea, deep learning, donors, endothelial cells, scleroderma, coup de sabre, eye banks, training
Trans. Vis. Sci. Tech.. 2024; 13(8):40. https://doi.org/10.1167/tvst.13.8.40

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Combined epigenetic treatment of human organ-cultured diabetic corneas with targeted nanoconjugate and a DNA demethylating agent ameliorates epithelial wound healing and stem cell marker expression

Alexander V Ljubimov; Andrei A Kramerov; Rameshwar Patil; Cynthia Amador; Onkar Sawant; Mehrnoosh Saghizadeh; Ruchi Shah

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):399.

ARVO Annual Meeting Abstract June 2024

Limbal Stem Cell Viability in Donor Corneas Following Eye Bank Storage

Jessica Ludwig; Alexa Thibodeau; Nambi Nallasamy; Shahzad Mian; Onkar Sawant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4463.

ARVO Annual Meeting Abstract June 2024

Retinal Output Dysfunction in a Model of Complete Congenital Stationary Night Blindness

Jake Khoussine; Abhilash Sawant; Raunak Sinha; Mrinalini Hoon

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6434.

ARVO Annual Meeting Abstract June 2024

Single-cell RNA sequencing reveals gene expression alterations in limbal epithelial subpopulations of human diabetic corneas

Ruchi Shah; Gianni Carraro; Adam J Poe; Yizhou Wang; Jake Inzalaco; Andrew Fealy; Cynthia Amador; Nagendra Verma; Onkar Sawant; Barry R Stripp; Alexander V Ljubimov; Mehrnoosh Saghizadeh

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6172.

ARVO Annual Meeting Abstract June 2023

Histatin-1 Decreases Corneal Endothelial Cell Death in Ex-Vivo Human Corneas

Onkar Sawant; Jessica Ludwig; Madison Castellanos; Dixie-Lee Shurland; Matt Chang; Ricardo Cruz; Patrick Hughes; James A Burke; Rhett M Schiffman

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):617.

ARVO Annual Meeting Abstract June 2023

Limbal Stem Cell Viability in FDA-Approved Corneal Storage Solution

Jessica Ludwig; Alexa Thibodeau; Nambi Nallasamy; Shahzad Mian; Onkar Sawant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3164.

ARVO Annual Meeting Abstract June 2022

Neurovascular clock genes in retinal vascular physiology and pathology

Vijay Jidigam; Rebecca Fuller; Onkar B Sawant; Kenya Wilcots; Richard A Lang; Sujata Rao

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4588 – F0450.

ARVO Annual Meeting Abstract June 2021

Effect of S-Nitrosylation on post-mortem donor cornea endothelial health during hypothermic storage period

Ahmed Omar; Onkar Sawant; James Reynolds; Kayla Jones; Stephanie How; Lin Zhu; Daniel Daroszewski; Jonathan H Lass

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):927.

ARVO Annual Meeting Abstract June 2021

Histological Characterization of Retinal Degeneration in Mucopolysaccharidosis Type IIIC

Onkar Sawant; Jill Wood; Srikanth Singamsetty; Stephanie How; Xuefang Pan; Vera L Bonilha; Sujata Rao; Alexey Pshezhetsky

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3237.

Visual Neuroscience November 2020

Thyroid Activating Enzyme, Deiodinase II Is Required for Photoreceptor Function in the Mouse Model of Retinopathy of Prematurity

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Onkar B. Sawant; Vijay K. Jidigam; Kenya Wilcots; Rebecca D. Fuller; Ivy Samuels; Sujata Rao

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):36. https://doi.org/10.1167/iovs.61.13.36

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Histological Characterization of Photoreceptor Degeneration in a Mouse Model of Mucopolysaccharidosis Type IIIC

Onkar Sawant; Jill Wood; Srikanth Singamsetty; Xuefang Pan; Sujata Rao; Alexey Pshezhetsky

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1298.

ARVO Annual Meeting Abstract June 2020

Assess the corneal epithelial toxicity of a second betadine soak after conjunctival removal to decrease donor tissue bioburden.

Kayla M Jones; Onkar Sawant; Michael Titus; Xiang Shen; Ali R Djalilian

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3275.

ARVO Annual Meeting Abstract June 2020

Use of novel hydrogel scaffold to assist Descemet’s Membrane Endothelial Keratoplasty (DMEK) surgery

Mark Daniell; Karl David Brown; Paul Gurr; Jean-Pierre Scheerlinck; Greg Dusting; Onkar Sawant; Michael Titus; Greg Qiao

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3601.

ARVO Annual Meeting Abstract July 2018

Circadian clock gene Bmal1 governs kinetics of retinal neurogenesis, lamination and visual evoked responses

Onkar Sawant; Olivia F Zucaro; Rebecca D Fuller; Minzhong Yu; Neal S Peachey; Sujata Rao

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3001.

ARVO Annual Meeting Abstract June 2017

Circadian clock gene Bmal1 is necessary to establish the S-opsin gradient in murine cone photoreceptors

Onkar Sawant; Amanda Horton; Ivy S Samuels; Sujata Rao

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5601.

ARVO Annual Meeting Abstract September 2016

Role of Type II deiodinase (Dio2) and circadian clock gene Bmal1 in photoreceptor development

Onkar Sawant; Banumathi Tamilselvan; Amanda Horton; Ivy S Samuels; Sujata Rao

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):563.

Retina December 2015

Light-Regulated Thyroid Hormone Signaling Is Required for Rod Photoreceptor Development in the Mouse Retina

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Onkar Sawant; Amanda M. Horton; Meenal Shukla; Mary E. Rayborn; Neal S. Peachey; Joe G. Hollyfield; Sujata Rao
TAGS: mice, retina, rhodopsin, rod photoreceptors, signal transduction, thyroid hormones, photoreceptors, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8248-8257. https://doi.org/10.1167/iovs.15-17743

Includes: Supplemental Content

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Identification of Wnt-5a Receptors Important in Diabetic and Non-Diabetic Corneal Epithelial Wound Healing

Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy

Automatic Determination of Endothelial Cell Density From Donor Cornea Endothelial Cell Images

Combined epigenetic treatment of human organ-cultured diabetic corneas with targeted nanoconjugate and a DNA demethylating agent ameliorates epithelial wound healing and stem cell marker expression

Limbal Stem Cell Viability in Donor Corneas Following Eye Bank Storage

Retinal Output Dysfunction in a Model of Complete Congenital Stationary Night Blindness

Single-cell RNA sequencing reveals gene expression alterations in limbal epithelial subpopulations of human diabetic corneas

Histatin-1 Decreases Corneal Endothelial Cell Death in Ex-Vivo Human Corneas

Limbal Stem Cell Viability in FDA-Approved Corneal Storage Solution

Neurovascular clock genes in retinal vascular physiology and pathology

Effect of S-Nitrosylation on post-mortem donor cornea endothelial health during hypothermic storage period

Histological Characterization of Retinal Degeneration in Mucopolysaccharidosis Type IIIC

Thyroid Activating Enzyme, Deiodinase II Is Required for Photoreceptor Function in the Mouse Model of Retinopathy of Prematurity

Histological Characterization of Photoreceptor Degeneration in a Mouse Model of Mucopolysaccharidosis Type IIIC

Assess the corneal epithelial toxicity of a second betadine soak after conjunctival removal to decrease donor tissue bioburden.

Use of novel hydrogel scaffold to assist Descemet’s Membrane Endothelial Keratoplasty (DMEK) surgery

Circadian clock gene Bmal1 governs kinetics of retinal neurogenesis, lamination and visual evoked responses

Circadian clock gene Bmal1 is necessary to establish the S-opsin gradient in murine cone photoreceptors

Role of Type II deiodinase (Dio2) and circadian clock gene Bmal1 in photoreceptor development

Light-Regulated Thyroid Hormone Signaling Is Required for Rod Photoreceptor Development in the Mouse Retina

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