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Glaucoma May 2025

Normative Variability in Retinal Nerve Fiber Layer Thickness: Does It Matter Where the Peaks Are?

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Sowjanya Gowrisankaran; Ashkan Abbasi; Xubo Song; Joel S. Schuman; Gadi Wollstein; Bhavna J. Antony; Hiroshi Ishikawa
TAGS: glaucoma, optic disk, retinal nerve fiber layer, retinal vessels
Trans. Vis. Sci. Tech.. 2025; 14(5):13. https://doi.org/10.1167/tvst.14.5.13

Clinical and Epidemiologic Research April 2025

Biological Age Acceleration, Genetic Susceptibility, and Incident Glaucoma Risk

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Wei-Qi Song; Wen-Fang Zhong; Zhi-Hao Li; Dan Liu; Jiao-Jiao Ren; Dong Shen; Jian Gao; Pei-Liang Chen; Jin Yang; Xiao-Meng Wang; Fang-Fei You; Chuan Li; Huan Chen; Jia-Hao Xie; Chen Mao
TAGS: glaucoma, genetic predisposition to disease
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):47. https://doi.org/10.1167/iovs.66.4.47

Includes: Supplemental Content

Visual Neuroscience April 2025

Astrocyte-Derived Extracellular Vesicles Alleviate Optic Nerve Injury Through Remodeling of Retinal Microenvironmental Homeostasis

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Lili Chen; Zhonghao Yu; Senmiao Zhu; Shihan Song; Guanwen He; Zai-Long Chi; Wencan Wu
TAGS: astrocytes, extracellular vesicles, micrornas, optic nerve injuries, rna, messenger, homeostasis, phosphate-buffered saline, wounds and injuries, retina
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):16. https://doi.org/10.1167/iovs.66.4.16

Includes: Supplemental Content

Lens April 2025

In Vivo Brillouin Analysis of Lens Nucleus and Cortex in Adult Myopic Eyes and Their Correlation With Accommodation

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Le Chang; Fen Song; Shijia Qu; Huazheng Cao; Yanan Wu; Lulu Xu; Jing Wang; Ruirui Zhang; Chao Xue; Yan Wang
TAGS: cell nucleus, eye, lens (device), lens, crystalline, myopia, visual accommodation, adult, regression analysis
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):6. https://doi.org/10.1167/iovs.66.4.6

Includes: Supplemental Content

Cornea & External Disease March 2025

Artificial Intelligence–Driven Detection of LASIK Using Corneal Optical Coherence Tomography Maps

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Jiachi Hong; Afshan A. Nanji; Richard D. Stutzman; Winston D. Chamberlain; Xubo Song; David Huang; Yan Li
TAGS: artificial intelligence, cornea, keratomileusis, laser in situ, maps, optical coherence tomography
Trans. Vis. Sci. Tech.. 2025; 14(3):17. https://doi.org/10.1167/tvst.14.3.17

Includes: Supplemental Content

Genetics March 2025

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

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Qiu-Yi Huo; Rui-Zheng Zhang; Wan-Nan Jia; Ya-Lei Wang; Xin Shen; Xin-Yao Chen; Tian-Hui Chen; Yan Liu; Ling-Hao Song; Xinyue Wang; Yong Lv; Ze-Xu Chen; Yong-Xiang Jiang
TAGS: biomechanics, cornea, ectopia lentis, fibrillin-1, marfan syndrome, mutation, genotype
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):23. https://doi.org/10.1167/iovs.66.3.23

Includes: Supplemental Content

Refractive Intervention March 2025

Evaluation of the Long-Term Corneal Biomechanics Following SMILE With Different Residual Stromal Bed Thickness in Rabbits

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Hongwei Qin; Xin Yang; Rui He; Yaowen Song; Junchao Wei; Xiaona Liu; Chenyan Wang; Ce Wu; Jie Hou; Zhipeng Gao; Lingfeng Chen; Xiaona Li; Weiyi Chen
TAGS: cornea, oryctolagus cuniculus, biomechanics, stress, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2025; 14(3):3. https://doi.org/10.1167/tvst.14.3.3

Includes: Supplemental Content

Glaucoma February 2025

Evaluation of Serum and Aqueous Humor Neurofilament Light Chain as Markers of Neurodegeneration in Glaucoma

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Jonathan B. Lin; Hani El Helwe; Henisk Falah; Bruno L. Hammerschlag; Stephanie A. Schultz; George Baldwin; Yixi Xue; Ryan A. Vasan; Christian Song; Kristine Lo; Austin Meeker; Silas L. Wang; Pia Kivisäkk; David Solá-Del Valle; Milica A. Margeta
TAGS: aqueous humor, glaucoma, nerve degeneration, neurofilament protein l, hypertension
Trans. Vis. Sci. Tech.. 2025; 14(2):24. https://doi.org/10.1167/tvst.14.2.24

Includes: Supplemental Content

Cornea February 2025

Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway

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Chao Wang; Yu-Zhi Li; Huan Guo; Shi-Rui Zhou; Xi Peng; Jia-Song Wang; Hua-Tao Xie; Ming-Chang Zhang
TAGS: lacrimal gland, nlr family, pyrin domain-containing 3 protein, sirt1 gene, melatonin, pathophysiology, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):51. https://doi.org/10.1167/iovs.66.2.51

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging February 2025

Changes in Optical Coherence Tomography Angiography Precede Clinical Onset of Placental Insufficiency

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Ye He; Pearl Heumann; Melissa Weilin Song; Shin Kadomoto; Srinivas R. Sadda; Ilina D. Pluym; Irena Tsui
TAGS: angiogram, optical coherence tomography, placental insufficiency, pregnancy
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):36. https://doi.org/10.1167/iovs.66.2.36

Lens February 2025

Advanced Artificial-Intelligence-Based Jiang Formula for Intraocular Lens Power in Congenital Ectopia Lentis

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Yan Liu; Xinyue Wang; Linghao Song; Yang Sun; Zexu Chen; Wannan Jia; Xin Shen; Yalei Wang; Xinyao Chen; Qiuyi Huo; Pranav Prakash Edavi; Tianhui Chen; Yongxiang Jiang
TAGS: ectopia lentis, eye, intelligence, intraocular lens implant device, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2025; 14(2):5. https://doi.org/10.1167/tvst.14.2.5

Includes: Supplemental Content

Cornea February 2025

Anatomic Relationship Among Descemet's Membrane, Trabecular Meshwork, Scleral Spur, and Ciliary Muscle

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Jost B. Jonas; Songhomitra Panda-Jonas; Jodhbir S. Mehta; Rahul A. Jonas
TAGS: body tissue, ciliary muscle, descemet's membrane, sclera, trabecular meshwork, eye, cornea
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):8. https://doi.org/10.1167/iovs.66.2.8

Glaucoma January 2025

SIRT4 Protects Retina Against Excitotoxic Injury by Promoting OPA1-Mediated Müller Glial Cell Mitochondrial Fusion and GLAST Expression

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Qian Ying; Hongdou Luo; Zhi Xie; Yi Huang; Haijian Hu; Ming Jin; Ke Xu; Yulian Pang; Yuning Song; Xu Zhang
TAGS: glutamate, glutamates, mitochondria, neuroglia, optic atrophy, autosomal dominant, proteins, retina, wounds and injuries, n-methylaspartate, retinal injuries
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):62. https://doi.org/10.1167/iovs.66.1.62

Retina January 2025

Systemic Sodium Iodate Injection as a Model for Expanding Geographic Atrophy

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Brandon D. Anderson; Brent A. Bell; Ying Song; Timothy T. Lee; Tan Wang; Joshua L. Dunaief
TAGS: age-related macular degeneration, nonexudative, atrophy, injections, iodates, sodium, mice, diagnostic imaging, retina
Trans. Vis. Sci. Tech.. 2025; 14(1):9. https://doi.org/10.1167/tvst.14.1.9

Includes: Supplemental Content

Retina January 2025

Anti-Syndecan 2 Antibody Treatment Reduces Edema Formation and Inflammation of Murine Laser-Induced CNV

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Federico Corti; Filippo Locri; Flavia Plastino; Paola Perrotta; Krisztina Zsebo; Emma Ristori; Xiangyun Yin; Eric Song; Helder André; Michael Simons
TAGS: antibodies, choroidal neovascularization, edema, inflammation, lasers, mice, syndecan, vascular endothelial growth factor a, anti-vascular endothelial growth factor therapy, intravitreal injections
Trans. Vis. Sci. Tech.. 2025; 14(1):10. https://doi.org/10.1167/tvst.14.1.10

Includes: Supplemental Content

Glaucoma October 2024

Low Intraocular Pressure Induces Fibrotic Changes in the Trabecular Meshwork and Schlemm's Canal of Sprague Dawley Rats

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Lijuan Xu; Yin Zhao; Xinyao Zhang; Xiaorui Gang; Jialing Han; Tao Zhou; Binyan Qi; Shuning Song; Ruiyi Ren; Yuanbo Liang
TAGS: intraocular pressure, rats, fibrosis, eye, schlemm's canal, trabecular meshwork
Trans. Vis. Sci. Tech.. 2024; 13(10):10. https://doi.org/10.1167/tvst.13.10.10

Includes: Supplemental Content

Artificial Intelligence September 2024

A Meta-Learning Approach for Classifying Multimodal Retinal Images of Retinal Vein Occlusion With Limited Data

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Danba Jiachu; Li Luo; Meng Xie; Xiaoling Xie; Jinming Guo; Hehua Ye; Kebo Cai; Lingling Zhou; Gang Song; Feng Jiang; Danqing Huang; Mingzhi Zhang; Ce Zheng
TAGS: datasets, learning, retinal vein occlusion, training
Trans. Vis. Sci. Tech.. 2024; 13(9):22. https://doi.org/10.1167/tvst.13.9.22

Vision Sciences Society Annual Meeting Abstract September 2024

More predictive, easier to detect? Contrast sensitivities in different predictability contexts

Seyoon Song; Minsun Park; Chai-Youn Kim

Journal of Vision. 2024; 24(10):814. https://doi.org/10.1167/jov.24.10.814

Vision Sciences Society Annual Meeting Abstract September 2024

Multiple-Object-Tracking Supported by Parvocellular, Magnocellular, and Koniocellular Pathways

Linan Shi; Yunjie Song; Sheng He

Journal of Vision. 2024; 24(10):822. https://doi.org/10.1167/jov.24.10.822

Vision Sciences Society Annual Meeting Abstract September 2024

The effect of fast flicker adaptation on contrast discrimination

Jaeseon Song; Bruno Breitmeyer; James Brown

Journal of Vision. 2024; 24(10):611. https://doi.org/10.1167/jov.24.10.611

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Normative Variability in Retinal Nerve Fiber Layer Thickness: Does It Matter Where the Peaks Are?

Biological Age Acceleration, Genetic Susceptibility, and Incident Glaucoma Risk

Astrocyte-Derived Extracellular Vesicles Alleviate Optic Nerve Injury Through Remodeling of Retinal Microenvironmental Homeostasis

In Vivo Brillouin Analysis of Lens Nucleus and Cortex in Adult Myopic Eyes and Their Correlation With Accommodation

Artificial Intelligence–Driven Detection of LASIK Using Corneal Optical Coherence Tomography Maps

Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis

Evaluation of the Long-Term Corneal Biomechanics Following SMILE With Different Residual Stromal Bed Thickness in Rabbits

Evaluation of Serum and Aqueous Humor Neurofilament Light Chain as Markers of Neurodegeneration in Glaucoma

Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway

Changes in Optical Coherence Tomography Angiography Precede Clinical Onset of Placental Insufficiency

Advanced Artificial-Intelligence-Based Jiang Formula for Intraocular Lens Power in Congenital Ectopia Lentis

Anatomic Relationship Among Descemet's Membrane, Trabecular Meshwork, Scleral Spur, and Ciliary Muscle

SIRT4 Protects Retina Against Excitotoxic Injury by Promoting OPA1-Mediated Müller Glial Cell Mitochondrial Fusion and GLAST Expression

Systemic Sodium Iodate Injection as a Model for Expanding Geographic Atrophy

Anti-Syndecan 2 Antibody Treatment Reduces Edema Formation and Inflammation of Murine Laser-Induced CNV

Low Intraocular Pressure Induces Fibrotic Changes in the Trabecular Meshwork and Schlemm's Canal of Sprague Dawley Rats

A Meta-Learning Approach for Classifying Multimodal Retinal Images of Retinal Vein Occlusion With Limited Data

More predictive, easier to detect? Contrast sensitivities in different predictability contexts

Multiple-Object-Tracking Supported by Parvocellular, Magnocellular, and Koniocellular Pathways

The effect of fast flicker adaptation on contrast discrimination

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