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Meeting Abstract (15)
Journal Articles (2)

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Investigative Ophthalmology & Visual Science (17)

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ARVO Annual Meeting Abstract (15)
Translational (2)

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Eye Anatomy and Disorders (2)
Imaging (2)
Retina (2)
Retinal Imaging (2)
Translational Research (2)
Biochemistry and Molecular Biology (1)
Genetics (1)
Nanotechnology and Regenerative Medicine (1)
Visual Neuroscience (1)

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bardet-biedl syndrome (2)
electroretinography (2)
mice (2)
eye (1)
gene therapy (1)
histology (1)
obesity (1)
proteins (1)
retina (1)
retinal degeneration (1)

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ARVO Annual Meeting Abstract June 2021

Subretinal gene replacement rescues retinal phenotype in BBS10 mouse

Arlene V Drack; Angela Mahoney; Sajag Bhattarai; Sara Mayer; Jacintha Thomas; Poppy Datta; Ying Hsu; Janelle Garrison; Elise Heon; Charles Searby; Luk H Vandenberghe; Seongjin Seo; Val Sheffield

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1178. doi:

ARVO Annual Meeting Abstract June 2021

BBS10 knockout mouse exhibits developmental lack of cone function and recapitulates retinal degeneration.

Sara Mayer; Jacintha Thomas; Angela Mahoney; Sajag Bhattarai; Qihong Zhang; Elliot Stalter; Poppy Datta; Ying Hsu; Janelle Garrison; Charles Searby; Seongjin Seo; Val Sheffield; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3070. doi:

ARVO Annual Meeting Abstract June 2020

Retinal degeneration in BBS10 mice is ameliorated by subretinal gene replacement

Arlene V Drack; Sajag Bhattarai; Jacintha Thomas; Elliot Stalter; Poppy Datta; ying Hsu; Janelle Garrison; Charles Searby; Luk H Vandenberghe; Elise Heon; Seongjin Seo; Val C Sheffield

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1914. doi:

ARVO Annual Meeting Abstract July 2019

AAV2/4-RS1 gene therapy in the retinoschisin knockout mouse model of X-linked retinoschisis

Brittni A Scruggs; Sajag Bhattarai; Ioana Cherascu; Megan Helms; Adisa Salesevic; Joseph Laird; Sheila A Baker; Budd Tucker; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4212. doi:

ARVO Annual Meeting Abstract July 2018

Assessment of transduction efficiency and tropism of different adeno-associated virus (AAV) serotypes based on route of delivery in rats

Ian C Han; Chunhua Jiao; Emily E Kaalberg; Sajag Bhattarai; Erin R Burnight; Budd A Tucker; Robert F Mullins; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5657. doi:

ARVO Annual Meeting Abstract September 2016

Electrophysiology and anatomy of the retina in albinism: is there a correlation with visual acuity?

Arlene V Drack; Zhaohui hu; Taylor Kehoe; Andrew Kemerley; Megan Helms; Sajag Bhattarai; wanda pfeifer

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3602. doi:

ARVO Annual Meeting Abstract June 2015

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in BBS

Seongjin Seo; Poppy Datta; Chantal Allamargot; Joseph Hudson; Emily Andersen; Sajag Bhattarai; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4644. doi:

ARVO Annual Meeting Abstract June 2015

Effect of operating microscope light on retinal function in common laboratory mice strains

Arlene V Drack; Uma Balakrishnan; Andrew Kemerley; Nicole Tatro; Alina Valentina Dumitrescu; Stewart Thompson; Sajag Bhattarai

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5415. doi:

ARVO Annual Meeting Abstract April 2014

Distinct profiles of abnormal ganglion cell activity in two forms of Leber’s congenital amaurosis (LCA): Implications for therapy

Steven F Stasheff; Kelsey N Spalding; Frederick R Blodi; Malini Shankar; Sajag Bhattarai; Stewart Thompson; Jeannette Bennicelli; Jean Bennett; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):357. doi:

ARVO Annual Meeting Abstract April 2014

Overcoming the overexpression toxicity of gene replacement therapy for Bardet Biedl Syndrome type 1

Arlene V Drack; Sajag Bhattarai; Seongjin Seo; Edwin M Stone; Val Sheffield; Robert Mullins; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4378. doi:

Translational Research September 2013

Subretinal Gene Therapy of Mice With Bardet-Biedl Syndrome Type 1

PDF

Seongjin Seo; Robert F. Mullins; Alina V. Dumitrescu; Sajag Bhattarai; Daniel Gratie; Kai Wang; Edwin M. Stone; Val Sheffield; Arlene V. Drack
TAGS: bardet-biedl syndrome, eye, gene therapy, mice, retina, electroretinography, spatial vectors, proteins, toxic effect
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):6118-6132. doi: https://doi.org/10.1167/iovs.13-11673

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2013

Vitritis in pediatric retinal degenerations

Maria Stunkel; Sajag Bhattarai; Edwin Stone; Kai Wang; Robert Mullins; Arlene Drack

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1168. doi:

ARVO Annual Meeting Abstract June 2013

Increasing body weight correlates with loss of ERG in mice with Bardet Biedl Syndrome

Arlene Drack; Sajag Bhattarai; Edwin Stone; Kai Wang; Daniel Gratie; Elise Heon; Val Sheffield; Robert Mullins

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6067. doi:

ARVO Annual Meeting Abstract June 2013

Optical Coherence Tomography (OCT) and histologic examination of a mouse model of chorioretinal coloboma

Sajag Bhattarai; Daniel Gratie; Maria Stunkel; Michael Anderson; Robert Mullins; Arlene Drack

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6095. doi:

ARVO Annual Meeting Abstract June 2013

Rpe65 gene therapy restores precise visual responses in vitro to many retinal ganglion cells in Rpe65 -/- mice

Steven Stasheff; Frederick Blodi; Malini Shankar; Jeannette Bennicelli; Jean Bennett; Sajag Bhattarai; Arlene Drack; Stewart Thompson

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):720. doi:

ARVO Annual Meeting Abstract March 2012

Subretinal gene therapy in Bbs1 mice

Arlene V. Drack; Sajag Bhattarai; Seongjin Seo; Dan Gratie; Edwin M. Stone; Robert Mullins; Val Sheffield

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6566. doi:

Translational Research January 2012

TUDCA Slows Retinal Degeneration in Two Different Mouse Models of Retinitis Pigmentosa and Prevents Obesity in Bardet-Biedl Syndrome Type 1 Mice

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Arlene V. Drack; Alina V. Dumitrescu; Sajag Bhattarai; Daniel Gratie; Edwin M. Stone; Robert Mullins; Val C. Sheffield
TAGS: bardet-biedl syndrome, electroretinography, mice, obesity, retinal degeneration, retinitis pigmentosa, histology
Invest. Ophthalmol. Vis. Sci.. 2012; 53(1):100-106. doi: https://doi.org/10.1167/iovs.11-8544

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
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