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ARVO Annual Meeting Abstract June 2023

Investigating the role of caspase-1 in a mouse model of juvenile X-linked retinoschisis

Araniko Pandey; Jacob Thompson; Ying Hsu; Sajag Bhattarai; Prajwal Gurung; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5214.

ARVO Annual Meeting Abstract June 2021

Subretinal gene replacement rescues retinal phenotype in BBS10 mouse

Arlene V Drack; Angela Mahoney; Sajag Bhattarai; Sara Mayer; Jacintha Thomas; Poppy Datta; Ying Hsu; Janelle Garrison; Elise Heon; Charles Searby; Luk H Vandenberghe; Seongjin Seo; Val Sheffield

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1178.

ARVO Annual Meeting Abstract June 2021

BBS10 knockout mouse exhibits developmental lack of cone function and recapitulates retinal degeneration.

Sara Mayer; Jacintha Thomas; Angela Mahoney; Sajag Bhattarai; Qihong Zhang; Elliot Stalter; Poppy Datta; Ying Hsu; Janelle Garrison; Charles Searby; Seongjin Seo; Val Sheffield; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3070.

ARVO Annual Meeting Abstract June 2020

Retinal degeneration in BBS10 mice is ameliorated by subretinal gene replacement

Arlene V Drack; Sajag Bhattarai; Jacintha Thomas; Elliot Stalter; Poppy Datta; ying Hsu; Janelle Garrison; Charles Searby; Luk H Vandenberghe; Elise Heon; Seongjin Seo; Val C Sheffield

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1914.

ARVO Annual Meeting Abstract July 2019

AAV2/4-RS1 gene therapy in the retinoschisin knockout mouse model of X-linked retinoschisis

Brittni A Scruggs; Sajag Bhattarai; Ioana Cherascu; Megan Helms; Adisa Salesevic; Joseph Laird; Sheila A Baker; Budd Tucker; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4212.

ARVO Annual Meeting Abstract July 2018

Assessment of transduction efficiency and tropism of different adeno-associated virus (AAV) serotypes based on route of delivery in rats

Ian C Han; Chunhua Jiao; Emily E Kaalberg; Sajag Bhattarai; Erin R Burnight; Budd A Tucker; Robert F Mullins; Edwin M Stone

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5657.

ARVO Annual Meeting Abstract September 2016

Electrophysiology and anatomy of the retina in albinism: is there a correlation with visual acuity?

Arlene V Drack; Zhaohui hu; Taylor Kehoe; Andrew Kemerley; Megan Helms; Sajag Bhattarai; wanda pfeifer

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3602.

ARVO Annual Meeting Abstract June 2015

Effect of operating microscope light on retinal function in common laboratory mice strains

Arlene V Drack; Uma Balakrishnan; Andrew Kemerley; Nicole Tatro; Alina Valentina Dumitrescu; Stewart Thompson; Sajag Bhattarai

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5415.

ARVO Annual Meeting Abstract June 2015

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in BBS

Seongjin Seo; Poppy Datta; Chantal Allamargot; Joseph Hudson; Emily Andersen; Sajag Bhattarai; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4644.

ARVO Annual Meeting Abstract April 2014

Distinct profiles of abnormal ganglion cell activity in two forms of Leber’s congenital amaurosis (LCA): Implications for therapy

Steven F Stasheff; Kelsey N Spalding; Frederick R Blodi; Malini Shankar; Sajag Bhattarai; Stewart Thompson; Jeannette Bennicelli; Jean Bennett; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):357.

ARVO Annual Meeting Abstract April 2014

Overcoming the overexpression toxicity of gene replacement therapy for Bardet Biedl Syndrome type 1

Arlene V Drack; Sajag Bhattarai; Seongjin Seo; Edwin M Stone; Val Sheffield; Robert Mullins; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4378.

Translational Research September 2013

Subretinal Gene Therapy of Mice With Bardet-Biedl Syndrome Type 1

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Seongjin Seo; Robert F. Mullins; Alina V. Dumitrescu; Sajag Bhattarai; Daniel Gratie; Kai Wang; Edwin M. Stone; Val Sheffield; Arlene V. Drack
TAGS: bardet-biedl syndrome, eye, gene therapy, mice, retina, electroretinography, spatial vectors, proteins, toxic effect
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):6118-6132. https://doi.org/10.1167/iovs.13-11673

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2013

Vitritis in pediatric retinal degenerations

Maria Stunkel; Sajag Bhattarai; Edwin Stone; Kai Wang; Robert Mullins; Arlene Drack

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1168.

ARVO Annual Meeting Abstract June 2013

Increasing body weight correlates with loss of ERG in mice with Bardet Biedl Syndrome

Arlene Drack; Sajag Bhattarai; Edwin Stone; Kai Wang; Daniel Gratie; Elise Heon; Val Sheffield; Robert Mullins

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6067.

ARVO Annual Meeting Abstract June 2013

Optical Coherence Tomography (OCT) and histologic examination of a mouse model of chorioretinal coloboma

Sajag Bhattarai; Daniel Gratie; Maria Stunkel; Michael Anderson; Robert Mullins; Arlene Drack

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6095.

ARVO Annual Meeting Abstract June 2013

Rpe65 gene therapy restores precise visual responses in vitro to many retinal ganglion cells in Rpe65 -/- mice

Steven Stasheff; Frederick Blodi; Malini Shankar; Jeannette Bennicelli; Jean Bennett; Sajag Bhattarai; Arlene Drack; Stewart Thompson

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):720.

ARVO Annual Meeting Abstract March 2012

Subretinal gene therapy in Bbs1 mice

Arlene V. Drack; Sajag Bhattarai; Seongjin Seo; Dan Gratie; Edwin M. Stone; Robert Mullins; Val Sheffield

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6566.

Translational Research January 2012

TUDCA Slows Retinal Degeneration in Two Different Mouse Models of Retinitis Pigmentosa and Prevents Obesity in Bardet-Biedl Syndrome Type 1 Mice

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Arlene V. Drack; Alina V. Dumitrescu; Sajag Bhattarai; Daniel Gratie; Edwin M. Stone; Robert Mullins; Val C. Sheffield
TAGS: bardet-biedl syndrome, electroretinography, mice, obesity, retinal degeneration, retinitis pigmentosa, histology
Invest. Ophthalmol. Vis. Sci.. 2012; 53(1):100-106. https://doi.org/10.1167/iovs.11-8544

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Investigating the role of caspase-1 in a mouse model of juvenile X-linked retinoschisis

Subretinal gene replacement rescues retinal phenotype in BBS10 mouse

BBS10 knockout mouse exhibits developmental lack of cone function and recapitulates retinal degeneration.

Retinal degeneration in BBS10 mice is ameliorated by subretinal gene replacement

AAV2/4-RS1 gene therapy in the retinoschisin knockout mouse model of X-linked retinoschisis

Assessment of transduction efficiency and tropism of different adeno-associated virus (AAV) serotypes based on route of delivery in rats

Electrophysiology and anatomy of the retina in albinism: is there a correlation with visual acuity?

Effect of operating microscope light on retinal function in common laboratory mice strains

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in BBS

Distinct profiles of abnormal ganglion cell activity in two forms of Leber’s congenital amaurosis (LCA): Implications for therapy

Overcoming the overexpression toxicity of gene replacement therapy for Bardet Biedl Syndrome type 1

Subretinal Gene Therapy of Mice With Bardet-Biedl Syndrome Type 1

Vitritis in pediatric retinal degenerations

Increasing body weight correlates with loss of ERG in mice with Bardet Biedl Syndrome

Optical Coherence Tomography (OCT) and histologic examination of a mouse model of chorioretinal coloboma

Rpe65 gene therapy restores precise visual responses in vitro to many retinal ganglion cells in Rpe65 -/- mice

Subretinal gene therapy in Bbs1 mice

TUDCA Slows Retinal Degeneration in Two Different Mouse Models of Retinitis Pigmentosa and Prevents Obesity in Bardet-Biedl Syndrome Type 1 Mice

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