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ARVO Annual Meeting Abstract June 2025

Mesopic and dark-adapted retinal sensitivity associated with type 1 macular neovascularization in AMD

Irmak Karaca; Yingjia Wei; Sandrine H. Künzel; Ray Nelson; Karen Daynes; Alicia Williams; Yue Zhang; Steffen Schmitz-Valckenberg; Monika Fleckenstein

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):668.

ARVO Annual Meeting Abstract June 2025

Structure-function correlation associated with type 1 macular neovascularization in AMD

Sandrine H. Künzel; Yingjia Wei; Irmak Karaca; Leon Alexander von der Emde; Ray Nelson; Karen Daynes; Alicia Williams; Frank G Holz; Yue Zhang; Steffen Schmitz-Valckenberg; Monika Fleckenstein

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):706.

ARVO Annual Meeting Abstract June 2025

Machine learning in normative data prediction for mesopic and dark-adapted microperimetry

Yingjia Wei; Leon Alexander von der Emde; Irmak Karaca; Sandrine H. Künzel; Steffen Schmitz-Valckenberg; Monika Fleckenstein; Yue Zhang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4078.

Retina January 2025

Deep Learning–Based SD-OCT Layer Segmentation Quantifies Outer Retina Changes in Patients With Biallelic RPE65 Mutations Undergoing Gene Therapy

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German Pinedo-Diaz; Birgit Lorenz; Sandrine H. Künzel; Sarah Thiele; Susana Ortega-Cisneros; Eduardo Bayro Corrochano; Frank G. Holz; Alexander Effland
TAGS: retina, rpe65 protein, spectral domain-optical coherence tomography, biological markers, deep learning, mutation, gene therapy, datasets
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):5. https://doi.org/10.1167/iovs.66.1.5

Includes: Supplemental Content

Retina December 2024

Prognostic Relevance of Relative Ellipsoid Zone Reflectivity for Ellipsoid Zone Loss in Macular Telangiectasia Type 2

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Lukas Goerdt; Jose Luis Rodriguez Garcia; Sandrine H. Künzel; Kristina Pfau; Kristin Raming; Simone Tzaridis; Matthias Schmid; Frank G. Holz; Ben Isselmann; Leonie Weinhold; Sarah Thiele
TAGS: patient prognosis, telangiectasis, spectral domain-optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):36. https://doi.org/10.1167/iovs.65.14.36

ARVO Annual Meeting Abstract June 2024

Deep-learning based quantification of RPE65- mutation inherited retinal degeneration from wide-angle images – novel biomarkers for natural history and interventional studies.

Birgit Lorenz; Eduardo Dávila-Meza; Sandrine H. Künzel; Frank G Holz; Eduardo Bayro-Corrochano; Alexander Effland

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1392.

ARVO Annual Meeting Abstract June 2024

Association of Ellipsoid Zone Reflectivity and Choriocapillaris Flow in Age-Related Macular Degeneration: a MACUSTAR study report

Yannick N. Liermann; Ben Isselmann; Marlene Sassmannshausen; Sandrine H. Künzel; Ulrich F O Luhmann; Sergio Leal; Matthias Schmid; Robert Finger; Steffen Schmitz-Valckenberg; Frank G Holz; Charlotte Behning; Sarah Thiele

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2315.

ARVO Annual Meeting Abstract June 2024

Reduced relative Ellipsoid Zone Reflectivity is associated with Ellipsoid Zone loss development and progression in Macular Telangiectasia Type 2

Lukas Goerdt; Leonie Weinhold; Ben Isselmann; Jose Luis Rodriguez; Sandrine H. Künzel; Kristina Pfau; Kristin Raming; Simone Tzaridis; Frank G Holz; Sarah Thiele

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3130.

ARVO Annual Meeting Abstract June 2024

Evaluation of early photoreceptor affection following successful retinal detachment surgery

Sandrine H. Künzel; Josua Sassen; Marlene Sassmannshausen; Lukas Goerdt; Yannick Liermann; Raffael G. Liegl; Philipp Herrmann; Robert Finger; Thomas Ach; Frank G Holz; Sarah Thiele

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6480.

ARVO Annual Meeting Abstract June 2024

Optic disc drusen in Pseudoxanthoma elasticum are associated with the extent of Bruch's membrane calcification

Kristin Raming; Sandrine H. Künzel; Maximilian Pfau; Doris Hendig; Frank G Holz; Kristina Pfau

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):404.

ARVO Annual Meeting Abstract June 2024

Geographic atrophy secondary to age-related macular degeneration: Significance of lesion location and functional determinants to vision-related quality of life

Eliza Eliza Broadbent; Sandrine H. Künzel; Philipp Möller; Moritz Linder; Lukas Goerdt; Joanna Czauderna; Steffen Schmitz-Valckenberg; Frank G Holz; Maximilian Pfau; Monika Fleckenstein

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5973.

Retina July 2023

Relative Ellipsoid Zone Reflectivity in Macular Telangiectasia Type 2

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Lukas Goerdt; Leonie Weinhold; Ben Isselmann; Jose Luis Rodriguez Garcia; Sandrine H. Künzel; Matthias Schmid; Frank G. Holz; Simone Tzaridis; Sarah Thiele
TAGS: eye, telangiectasis, spectral domain-optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2023; 64(10):21. https://doi.org/10.1167/iovs.64.10.21

ARVO Annual Meeting Abstract June 2023

Functional benefits of subretinal gene augmentation therapy with Voretigene Neparvovec for inherited retinal disease associated with biallelic mutations in RPE65

Birgit Lorenz; Markus N Preising; Johanna Pauline Scholz; Sandrine H. Künzel; Philipp Herrmann; Frank G Holz

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):987.

ARVO Annual Meeting Abstract June 2023

Longitudinal characterization of chorioretinal atrophies after subretinal gene augmentation therapy with Voretigene Neparvovec in RPE65 -mediated retinal degeneration

Sandrine H. Künzel; Marlene Sassmannshausen; Josua Sassen; Markus N Preising; Frank G Holz; Birgit Lorenz; Philipp Herrmann

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5006.

ARVO Annual Meeting Abstract June 2022

Transcriptome analysis of the human choroid qualifies endothelial androgen responses as a disease driver for Central Serous Chorioretinopathy

Steffen Emil Künzel; Sandrine Helene Künzel; Dominik Pascal Frentzel; Dominika Pohlmann; Lynn Zur Bonsen; Oliver Zeitz; Antonia M. Joussen; Alexandre Dubrac

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):39.

Low Vision May 2020

Determinants of Quality of Life in Geographic Atrophy Secondary to Age-Related Macular Degeneration

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Sandrine H. Künzel; Philipp T. Möller; Moritz Lindner; Lukas Goerdt; Jennifer Nadal; Matthias Schmid; Steffen Schmitz-Valckenberg; Frank G. Holz; Monika Fleckenstein; Maximilian Pfau
TAGS: age-related macular degeneration, atrophy, eye, quality of life, vision, reading (activity), biological markers
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):63. https://doi.org/10.1167/iovs.61.5.63

Includes: Supplemental Content

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Mesopic and dark-adapted retinal sensitivity associated with type 1 macular neovascularization in AMD

Structure-function correlation associated with type 1 macular neovascularization in AMD

Machine learning in normative data prediction for mesopic and dark-adapted microperimetry

Deep Learning–Based SD-OCT Layer Segmentation Quantifies Outer Retina Changes in Patients With Biallelic RPE65 Mutations Undergoing Gene Therapy

Prognostic Relevance of Relative Ellipsoid Zone Reflectivity for Ellipsoid Zone Loss in Macular Telangiectasia Type 2

Deep-learning based quantification of RPE65- mutation inherited retinal degeneration from wide-angle images – novel biomarkers for natural history and interventional studies.

Association of Ellipsoid Zone Reflectivity and Choriocapillaris Flow in Age-Related Macular Degeneration: a MACUSTAR study report

Reduced relative Ellipsoid Zone Reflectivity is associated with Ellipsoid Zone loss development and progression in Macular Telangiectasia Type 2

Evaluation of early photoreceptor affection following successful retinal detachment surgery

Optic disc drusen in Pseudoxanthoma elasticum are associated with the extent of Bruch's membrane calcification

Geographic atrophy secondary to age-related macular degeneration: Significance of lesion location and functional determinants to vision-related quality of life

Relative Ellipsoid Zone Reflectivity in Macular Telangiectasia Type 2

Functional benefits of subretinal gene augmentation therapy with Voretigene Neparvovec for inherited retinal disease associated with biallelic mutations in RPE65

Longitudinal characterization of chorioretinal atrophies after subretinal gene augmentation therapy with Voretigene Neparvovec in RPE65 -mediated retinal degeneration

Transcriptome analysis of the human choroid qualifies endothelial androgen responses as a disease driver for Central Serous Chorioretinopathy

Determinants of Quality of Life in Geographic Atrophy Secondary to Age-Related Macular Degeneration

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