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ARVO Annual Meeting Abstract June 2025

Cerebrospinal fluid (CSF) delivery of AAV9-Bic-HEXA/HEXB improves optic nerve and retinal pathology in sheep with Tay-Sachs disease

Brett D Story; Sara M Thomasy; Sara A Adelman; Toloo Taghian; Hikaru Shiraishi; Monica Ardon; Maria Do; Leandro Teixeira; Gillian C Shaw; Nicholas Marsh-Armstrong; Heather L Gray-Edwards

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1633.

ARVO Annual Meeting Abstract June 2025

A cross-species comparison of the role of noggin in corneal endothelial health and disease

Sara M Thomasy; Karolina Roszak; Rachel Brady; Julia Malvick; Raneesh Ramarapu; M. Isabel Casanova; Sangwan Park; Xin Gong; Chao Xing; Connor Chang; Allysa Hoehn; Andrew Blandino; Ariana Marangakis; Monica Motta; Michelle Ferneding; Nayeli Echeverria; Monica Ardon; Brian Leonard; Vinod V Mootha; Rebecca Bellone

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2961.

ARVO Annual Meeting Abstract June 2025

A pilot study quantifying the corneal leukocytes by flow cytometry in Awat2 knockout mice

Erinn Mills; Erin Hisey; Nayone Lantyer Araujo; Sara M Thomasy; Hannah Savage; Brian Leonard

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5644.

ARVO Annual Meeting Abstract June 2025

Age-related retinal ganglion cell changes in a nonhuman primate model of autosomal dominant optic atrophy

Jaegook Lim; Ana Cláudia Santos Raposo; Michaela Dunn; Ana Ripolles-Garcia; Monica Motta; Karen Anderson; Glenn Yiu; Ala Moshiri; Brad Fortune; Brian Leonard; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1072.

ARVO Annual Meeting Abstract June 2025

Reference data on optic nerve flavoprotein fluorescence in normal rhesus macaques

Ana Ripolles-Garcia; Ana Cláudia Santos Raposo; Jaegook Lim; Monica Motta; Carol Villafuerte-Trisolini; Karen Anderson; Nadeen Habbas-Nimer; Collin Rich; Glenn Yiu; Ala Moshiri; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4776.

ARVO Annual Meeting Abstract June 2025

In vitro treatment with Isoliquiritigenin inhibits ANGPTL7 upregulation in human trabecular meshwork cells

Nayone Lantyer Araujo; Sanjana Allaparthi; Weinong Song; Sara M Thomasy; Brian Leonard

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3001.

ARVO Annual Meeting Abstract June 2025

Pharmacokinetics and pharmacodynamics of a novel species-inspired lipid therapy (rNPL593) for the treatment of dry eye disease and potential mechanism of action

Brian Leonard; Nayone Lantyer Araujo; Erin Hisey; Monserrath Camacho Ayala; Sara M Thomasy; Igor A Butovich; Daniel M Albert; Christopher J Murphy; Thomas R Gadek; Charles A O’Neill

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1604.

ARVO Annual Meeting Abstract June 2025

Tubulin subtype expression patterns developmental origins and cellular morphology of embryonic corneal cell types

Raneesh Ramarapu; William Stoehr; Mia Miesen; Sara M Thomasy; Crystal D. Rogers; Brian Leonard

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1380.

ARVO Annual Meeting Abstract June 2025

The Opa1 em1(IMPC)Bay mouse is not a useful model of autosomal dominant optic atrophy (ADOA).

Uchenna Nlebedum; Ja HO Shim; Ana Cláudia Santos Raposo; Daniela Santamaría Muñoz; Meher Khan; Raenier Reyes; Anna La Torre; Nicholas Marsh-Armstrong; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1106.

ARVO Annual Meeting Abstract June 2025

Impact of high fat and sugar diet on drusen progression in a nonhuman primate model of age-related macular degeneration

Sophie M Le; Carol Villafuerte-Trisolini; Tony Shen; Megan Gong; Sruthi Ramesh Kumar; Tzu-Ni Sin; Kevin Choy; Sina Farsiu; Peter Havel; Sara M Thomasy; Glenn Yiu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1899.

ARVO Annual Meeting Abstract June 2025

Mucin 4 deficient mice exhibit anatomical and functional decreases in their corneal barrier with reduced corneal innervation

Erin Hisey; Ana Sandoval-Castellanos; Sonali Pal-Ghosh; Michelle Ferneding; Sangwan Park; Nayone Lantyer Araujo; Yifan Lai; Sara A Adelman; Sara M Thomasy; Pablo Argueso; Min Zhao; Mary Ann Stepp; Brian Leonard

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1897.

ARVO Annual Meeting Abstract June 2025

Unlocking the therapeutic potential of the corneal endothelium: Intravital imaging reveals endogenous regenerative capabilities

Panteleimon Rompolas; Ezra Curtis; Raneesh Ramarapu; Maxwell Marshall; Heesuk Yoo; Sangwan Park; Brian Leonard; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2947.

ARVO Annual Meeting Abstract June 2025

Impact of diet and gut microbiome on nonhuman primate models of age-related macular degeneration

Aaron Siegman; Yanshan Jin; Angela Zivkovic; Carol Villafuerte-Trisolini; Sophie M Le; Annie Zhang; Yin Allison Liu; Peter Havel; Sara M Thomasy; Glenn Yiu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2644.

ARVO Annual Meeting Abstract June 2025

Plasma metabolomics in drusen and drusenoid lesions in nonhuman primates

Carol Villafuerte-Trisolini; Yin Allison Liu; Annie Zhang; Sophie M Le; Tzu-Ni Sin; Oliver Fiehn; Christopher Brydges; Ines Lains; Deeba Husain; Kevin Mendez; Angel Rose Joshy; Sara M Thomasy; Glenn Yiu

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3996.

Retina May 2025

Clic6 Deficiency Triggers Aberrant Apical Microvilli in RPE

PDF

Sangwan Park; Naran Suvarnpradip; Niusha Kasiri; Glenn Yiu; Sara M. Thomasy; Denise M. Imai; K. C. Kent Lloyd; Brian C. Leonard; Ala Moshiri
TAGS: mice, microvilli, precipitating factors, retina
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):44. https://doi.org/10.1167/iovs.66.5.44

Includes: Supplemental Content

Retina September 2023

Choroidal Changes in Rhesus Macaques in Aging and Age-Related Drusen

PDF

Yevgeniy Sazhnyev; Tzu-Ni Sin; Anthony Ma; Ellie Chang; Leon Huynh; Karolina Roszak; Sangwan Park; Kevin Choy; Sina Farsiu; Ala Moshiri; Sara M. Thomasy; Glenn Yiu
TAGS: aging, drusen, macaca mulatta
Invest. Ophthalmol. Vis. Sci.. 2023; 64(12):44. https://doi.org/10.1167/iovs.64.12.44

Includes: Supplemental Content

Retina June 2023

Chromatic Pupillometry as a Putative Screening Tool for Heritable Retinal Disease in Rhesus Macaques

PDF

Elyse M. Salpeter; Ala Moshiri; Michelle Ferneding; Monica J. Motta; Sangwan Park; Chrisoula Skouritakis; Sara M. Thomasy
TAGS: macaca mulatta, pupillometry, retinal diseases, screening, dark adaptation
Trans. Vis. Sci. Tech.. 2023; 12(6):13. https://doi.org/10.1167/tvst.12.6.13

Includes: Supplemental Content

Cornea June 2023

Type II Diabetes Mellitus Causes Extracellular Matrix Alterations in the Posterior Cornea That Increase Graft Thickness and Rigidity

PDF

Kenten D. Kingsbury; Jessica M. Skeie; Krista Cosert; Gregory A. Schmidt; Benjamin T. Aldrich; Christopher S. Sales; Julia Weller; Friedrich Kruse; Sara M. Thomasy; Ursula Schlötzer-Schrehardt; Mark A. Greiner
TAGS: body tissue, cornea, diabetes mellitus, diabetes mellitus, type 2, donors, muscle rigidity, proteins, tissue transplants, extracellular matrix, age
Invest. Ophthalmol. Vis. Sci.. 2023; 64(7):26. https://doi.org/10.1167/iovs.64.7.26

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Multimodal corneal imaging to characterize a novel central stromal dystrophy in dog

Ana Cláudia Raposo; Sangwan Park; Sophie M Le; Michelle Ferneding; Elyse Salpeter; Bret Moore; Brian Leonard; Sara M Thomasy

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4037.

ARVO Annual Meeting Abstract June 2023

Chromatic Electroretinography in Non-human Primates with and without PDE6C-associated Achromatopsia

Monica Motta; Quentin Davis; Michelle Ferneding; Sangwan Park; Kira H Lin; Rui Chen; Jeffrey Rogers; Tim Stout; Sara M Thomasy; Ala Moshiri

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5228.

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Cerebrospinal fluid (CSF) delivery of AAV9-Bic-HEXA/HEXB improves optic nerve and retinal pathology in sheep with Tay-Sachs disease

A cross-species comparison of the role of noggin in corneal endothelial health and disease

A pilot study quantifying the corneal leukocytes by flow cytometry in Awat2 knockout mice

Age-related retinal ganglion cell changes in a nonhuman primate model of autosomal dominant optic atrophy

Reference data on optic nerve flavoprotein fluorescence in normal rhesus macaques

In vitro treatment with Isoliquiritigenin inhibits ANGPTL7 upregulation in human trabecular meshwork cells

Pharmacokinetics and pharmacodynamics of a novel species-inspired lipid therapy (rNPL593) for the treatment of dry eye disease and potential mechanism of action

Tubulin subtype expression patterns developmental origins and cellular morphology of embryonic corneal cell types

The Opa1 em1(IMPC)Bay mouse is not a useful model of autosomal dominant optic atrophy (ADOA).

Impact of high fat and sugar diet on drusen progression in a nonhuman primate model of age-related macular degeneration

Mucin 4 deficient mice exhibit anatomical and functional decreases in their corneal barrier with reduced corneal innervation

Unlocking the therapeutic potential of the corneal endothelium: Intravital imaging reveals endogenous regenerative capabilities

Impact of diet and gut microbiome on nonhuman primate models of age-related macular degeneration

Plasma metabolomics in drusen and drusenoid lesions in nonhuman primates

Clic6 Deficiency Triggers Aberrant Apical Microvilli in RPE

Choroidal Changes in Rhesus Macaques in Aging and Age-Related Drusen

Chromatic Pupillometry as a Putative Screening Tool for Heritable Retinal Disease in Rhesus Macaques

Type II Diabetes Mellitus Causes Extracellular Matrix Alterations in the Posterior Cornea That Increase Graft Thickness and Rigidity

Multimodal corneal imaging to characterize a novel central stromal dystrophy in dog

Chromatic Electroretinography in Non-human Primates with and without PDE6C-associated Achromatopsia

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