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ARVO Annual Meeting Abstract June 2025

Tertiary lymphoid structures in a mouse model of Sjögren's disease

Sara Abdelhamid; Alison V. Ramirez; Maria C. Edman; J. Andrew MacKay; Sarah F. Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5522.

ARVO Annual Meeting Abstract June 2025

PIKfyve inhibition alters lacrimal gland endosomal and autophagic traffic in a murine model of Sjögren's Disease

Cindy Toscano; Alison V. Ramirez; Maria C. Edman; Sarah F. Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6068.

ARVO Annual Meeting Abstract June 2025

Quantitative Proteomic Analysis of Tears from a Sjögren's Disease Mouse Model

Xiaoyang Li; Mario Alba; Chenyi Wang; Maria C. Edman; Julian Whitelegge; Sarah F. Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1201.

ARVO Annual Meeting Abstract June 2025

Accumulation of lipids in the aged lacrimal gland

Cintia S De Paiva; Sydney Krenz; Prashant Kumar; Kaitlin Karen Scholand; Zhiyuan Yu; Seher Yuksel; Helen P Makarenkova; Sarah F Hamm-Alvarez; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1892.

ARVO Annual Meeting Abstract June 2024

Thermosensitive elastin-like polypeptides bind pro-inflammatory IL-17A and form local depots following supra-lacrimal injection

Shin-Jae Lee; Sara Abdelhamid; Quratulain Bhatti; Maria Edman; Sarah F Hamm-Alvarez; J. Andrew MacKay

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4594.

Physiology and Pharmacology June 2024

The Aging Lacrimal Gland of Female C57BL/6J Mice Exhibits Multinucleate Macrophage Infiltration Associated With Lipid Dysregulation

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Minchang Choi; Cindy Toscano; Maria C. Edman; Cintia S. de Paiva; Sarah F. Hamm-Alvarez
TAGS: aging, langer-giedion syndrome, lipids, macrophages, mice, niemann-pick disease, type c, mice, inbred c57bl, proteins, fluorescent antibody technique, lacrimal gland
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):1. https://doi.org/10.1167/iovs.65.6.1

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2023

Evidence for lipid dysregulation associated with inflammation in lacrimal glands from aged female C57BL/6J mice

Minchang Choi; Cindy Toscano; Maria Edman; Sarah F Hamm-Alvarez; Cintia S. De Paiva

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):695.

Immunology and Microbiology April 2023

The miRNA Landscape of Lacrimal Glands in a Murine Model of Autoimmune Dacryoadenitis

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Shruti Singh Kakan; Xiaoyang Li; Maria C. Edman; Curtis T. Okamoto; Brooke E. Hjelm; Sarah F. Hamm-Alvarez
TAGS: dacryoadenitis, mice, micrornas, autoimmunity, sjogren's syndrome, mice, inbred nod, lacrimal gland
Invest. Ophthalmol. Vis. Sci.. 2023; 64(4):1. https://doi.org/10.1167/iovs.64.4.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Identification of miRNAs in tears of a murine model of Sjögren’s syndrome that may represent putative diagnostic biomarkers

Shruti Singh Kakan; Maria Edman; Brooke Erika Hjelm; Curtis T Okamoto; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3473.

ARVO Annual Meeting Abstract June 2021

Changes in expression of regulators of protein phosphatase 2A are observed in lacrimal gland from a murine model of Sjögren’s syndrome

Minchang Choi; Hao Guo; Maria Edman; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3467.

Articles July 2020

Reduced Expression of VEGF-A in Human Retinal Pigment Epithelial Cells and Human Muller Cells Following CRISPR-Cas9 Ribonucleoprotein-Mediated Gene Disruption

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Hossein Ameri; Christopher Murat; Amirmohsen Arbabi; Wei Jiang; Srikanth R. Janga; Peter Zhifeng Qin; Sarah F. Hamm-Alvarez
TAGS: crispr-cas9, genes, radial retinal glial cell, vascular endothelial growth factor a, retinal pigment cell, ribonucleoproteins
Trans. Vis. Sci. Tech.. 2020; 9(8):23. https://doi.org/10.1167/tvst.9.8.23

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Intralacrimal Delivery of Rapa Shows Therapeutic Effects Without Systemic Toxicity in NOD Mice

Yaping Ju; Maria Edman; Hao Guo; Srikanth Reddy Janga; Santosh Peddi; J.Andrew MacKay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):144.

ARVO Annual Meeting Abstract June 2020

Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren’s syndrome murine model

Runzhong Fu; Hao Guo; Srikanth Reddy Janga; Minchang Choi; Wannita Klinngam; Maria Edman; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1963.

ARVO Annual Meeting Abstract July 2019

Multivalent Lacripep Elastin-Like Polypeptide fusions initiate calcium signaling and prosecretory activity in cells of the ocular surface system

Changrim Lee; Maria Edman; Sarah F Hamm-Alvarez; John Andrew MacKay

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):308.

ARVO Annual Meeting Abstract July 2019

Development of a targeted carrier for Rapamycin in a murine model of Sjögren’s syndrome

Yaping Ju; Hao Guo; Frances Yarber; Maria Edman; Santosh Peddi; Srikanth Reddy Janga; John Andrew MacKay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2822.

ARVO Annual Meeting Abstract July 2019

Tear biomarkers for Sjögren Syndrome

Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3287.

ARVO Annual Meeting Abstract July 2019

The α 1 -adrenergic agonist, phenylephrine, increases tear cathepsin S secretion through a Rab27a-independent pathway

Runzhong Fu; Srikanth Reddy Janga; Maria Edman; Frances Yarber; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4195.

ARVO Annual Meeting Abstract July 2019

Tear biomarkers for Parkinson’s disease in basal versus reflex tears

Maria C Edman; Srikanth Reddy Janga; Daniel Freire; Danielle Feigenbaum; Wendy Mack; Curtis T Okamoto; Mark F Lew; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4196.

ARVO Annual Meeting Abstract July 2019

Analysis of CD4+ T cell populations in male NOD mice highlights the potential of local administration of cyclosporine A in the treatment of Sjögren’s syndrome

Hao Guo; John Andrew MacKay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):279.

ARVO Annual Meeting Abstract July 2018

Tear Proteins as Possible Biomarkers for Parkinson’s Disease

Sarah F Hamm-Alvarez; Mark Lew; Danielle Feigenbaum; Srikanth Reddy Janga; Mihir Shah; Daniel Freire; Benjamin Cooperman; Raveena Ghanshani; Wendy Mack; Curtis Okamoto

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4909.

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Tertiary lymphoid structures in a mouse model of Sjögren's disease

PIKfyve inhibition alters lacrimal gland endosomal and autophagic traffic in a murine model of Sjögren's Disease

Quantitative Proteomic Analysis of Tears from a Sjögren's Disease Mouse Model

Accumulation of lipids in the aged lacrimal gland

Thermosensitive elastin-like polypeptides bind pro-inflammatory IL-17A and form local depots following supra-lacrimal injection

The Aging Lacrimal Gland of Female C57BL/6J Mice Exhibits Multinucleate Macrophage Infiltration Associated With Lipid Dysregulation

Evidence for lipid dysregulation associated with inflammation in lacrimal glands from aged female C57BL/6J mice

The miRNA Landscape of Lacrimal Glands in a Murine Model of Autoimmune Dacryoadenitis

Identification of miRNAs in tears of a murine model of Sjögren’s syndrome that may represent putative diagnostic biomarkers

Changes in expression of regulators of protein phosphatase 2A are observed in lacrimal gland from a murine model of Sjögren’s syndrome

Reduced Expression of VEGF-A in Human Retinal Pigment Epithelial Cells and Human Muller Cells Following CRISPR-Cas9 Ribonucleoprotein-Mediated Gene Disruption

Intralacrimal Delivery of Rapa Shows Therapeutic Effects Without Systemic Toxicity in NOD Mice

Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren’s syndrome murine model

Multivalent Lacripep Elastin-Like Polypeptide fusions initiate calcium signaling and prosecretory activity in cells of the ocular surface system

Development of a targeted carrier for Rapamycin in a murine model of Sjögren’s syndrome

Tear biomarkers for Sjögren Syndrome

The α 1 -adrenergic agonist, phenylephrine, increases tear cathepsin S secretion through a Rab27a-independent pathway

Tear biomarkers for Parkinson’s disease in basal versus reflex tears

Analysis of CD4+ T cell populations in male NOD mice highlights the potential of local administration of cyclosporine A in the treatment of Sjögren’s syndrome

Tear Proteins as Possible Biomarkers for Parkinson’s Disease

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