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Retinal Cell Biology August 2020

Effects of Diabetes on Mitochondrial Morphology and Its Implications in Diabetic Retinopathy

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Dongjoon Kim; Sayon Roy
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, language morphology, mitochondria, morphology, optic atrophy, autosomal dominant, cytochrome c, down-regulation, retina
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):10. https://doi.org/10.1167/iovs.61.10.10

Retinal Cell Biology April 2020

High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy

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Ngan-Ha Nguyen; Dongjoon Kim; Sayon Roy
TAGS: diabetic retinopathy, extracellular matrix, extracellular matrix proteins, glucose, protein measurement, total, protein-lysine 6-oxidase, proteins, ammonium hydroxide
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):40. https://doi.org/10.1167/iovs.61.4.40

ARVO Annual Meeting Abstract July 2019

High Glucose Increases Binding of Lysyl Oxidase with Extracellular Matrix Proteins in Retinal Endothelial Cells: Implications for Diabetic Retinopathy

Ngan Ha Nguyen; Dongjoon Kim; Philip C. Trackman; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2699.

Retinal Cell Biology December 2018

Inhibition of Diabetes-Induced Lysyl Oxidase Overexpression Prevents Retinal Vascular Lesions Associated With Diabetic Retinopathy

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Brian Song; Dongjoon Kim; Ngan-Ha Nguyen; Sayon Roy
TAGS: diabetes mellitus, diabetic retinopathy, protein overexpression, protein-lysine 6-oxidase, rna, small interfering, vascular lesions, retina, rats
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5965-5972. https://doi.org/10.1167/iovs.18-25543

ARVO Annual Meeting Abstract June 2017

Administration of a gap junction coupler reduces retinal vascular cell loss associated with diabetic retinopathy

Dongjoon Kim; Dayeun Lee; Ulrik Mouritzen; Bjarne Due Larsen; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4030.

ARVO Annual Meeting Abstract June 2017

Role of high glucose-induced lysyl oxidase overexpression on Ras activity in rat retinal endothelial cells

Brian Chirn; Dongjoon Kim; Philip C Trackman; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4040.

Retinal Cell Biology June 2017

High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy

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Thomas Tien; Joyce Zhang; Tetsuya Muto; Dongjoon Kim; Vijay P. Sarthy; Sayon Roy
TAGS: diabetic retinopathy, glucose, mitochondria, mitomycin, pathophysiology, cytochrome c
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2915-2921. https://doi.org/10.1167/iovs.16-21355

Retinal Cell Biology May 2017

Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose–Induced Apoptosis

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Dongjoon Kim; Robert P. Mecham; Philip C. Trackman; Sayon Roy
TAGS: apoptosis, down-regulation, endothelial cells, glucose, protein-lysine 6-oxidase, proto-oncogene proteins c-akt, diabetes mellitus, rna, small interfering, caspase-3, protein overexpression
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2725-2731. https://doi.org/10.1167/iovs.16-21340

ARVO Annual Meeting Abstract September 2016

Intravitreal Aflibercept reduces the retinal vessel diameter in patients with diabetic macular edema

Andrea Consigli; Athanasios Papanastasiou; Sayon Roy; Gabriele Thumann; Argyrios Chronopoulos

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2118.

ARVO Annual Meeting Abstract September 2016

High Glucose-induced Changes in Mitochondrial Membrane Potential, Oxygen Consumption Rate, and Extracellular Acidification Promotes Mitochondrial Dysfunction in Retinal Endothelial and Müller Cells.

Franco Aparecido Aparecido Rossato; Joyce Zhang; Vijay P Sarthy; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5437.

ARVO Annual Meeting Abstract June 2015

Fluorescence lifetime imaging microscopy on retinal microvascular endothelial cells under high glucose conditions

Yoko Miura; Eric Beck; Gereon Huttmann; Sayon Roy; Ralf Brinkmann

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5943.

ARVO Annual Meeting Abstract June 2015

HG-induced upregulation of rab20 expression disrupts gap junctional intercellular communication and promotes retinal Müller cell (rMC) death

Dongjoon Kim; Vijay P Sarthy; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):408.

ARVO Annual Meeting Abstract June 2015

Differential effects of high glucose on connexin 43 hemichannels in compact versus sparsely grown retinal endothelial cells

Edward Bae; Dongjoon Kim; Jean X Jiang; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4272.

ARVO Annual Meeting Abstract June 2015

High glucose-induced decrease in claudin-5 expression is facilitated by connexin 43 (Cx43) downregulation in retinal endothelial cells.

Shruti Amin; Haares Mirzan; Dongjoon Kim; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4278.

Retinal Cell Biology July 2014

High Glucose Alters Cx43 Expression and Gap Junction Intercellular Communication in Retinal Müller Cells: Promotes Müller Cell and Pericyte Apoptosis

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Tetsuya Muto; Thomas Tien; Dongjoon Kim; Vijay P. Sarthy; Sayon Roy
TAGS: apoptosis, connexin 43, pericytes, coculture techniques, gap junction protein
Invest. Ophthalmol. Vis. Sci.. 2014; 55(7):4327-4337. https://doi.org/10.1167/iovs.14-14606

ARVO Annual Meeting Abstract April 2014

Effects of High Glucose-Induced Cx43 Downregulation on Claudin-5 Expression and Cell Monolayer Permeability in Retinal Endothelial Cells

Rhonda Sue Silva; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4903.

ARVO Annual Meeting Abstract April 2014

Downregulation of Connexin 43 Expression and Gap Junction Intercellular Communication Promotes Apoptosis in Retinal Müller Cells

Sayon Roy; Tetsuya Muto; Thomas Tien; Vijay P Sarthy

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5822.

ARVO Annual Meeting Abstract April 2014

Direct downregulation of Connexin 43 expression promotes retinal vascular cell loss characteristic of diabetic retinopathy.

Tetsuya Muto; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5831.

Retinal Cell Biology October 2013

Effects of High Glucose-Induced Cx43 Downregulation on Occludin and ZO-1 Expression and Tight Junction Barrier Function in Retinal Endothelial Cells

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Thomas Tien; Kevin F. Barrette; Argyrios Chronopoulos; Sayon Roy
TAGS: connexin 43, down-regulation, tight junctions, glucose, endothelial cells
Invest. Ophthalmol. Vis. Sci.. 2013; 54(10):6518-6525. https://doi.org/10.1167/iovs.13-11763

ARVO Annual Meeting Abstract June 2013

High Glucose-Induced Connexin 43 (Cx43) Downregulation Modulates Rho/Rho kinase (ROCK) Signaling and Promotes Apoptosis in Retinal Endothelial Cells

Tetsuya Muto; Sayon Roy

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2687.

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Effects of Diabetes on Mitochondrial Morphology and Its Implications in Diabetic Retinopathy

High Glucose Increases Binding of Lysyl Oxidase to Extracellular Matrix Proteins: Implications for Diabetic Retinopathy

High Glucose Increases Binding of Lysyl Oxidase with Extracellular Matrix Proteins in Retinal Endothelial Cells: Implications for Diabetic Retinopathy

Inhibition of Diabetes-Induced Lysyl Oxidase Overexpression Prevents Retinal Vascular Lesions Associated With Diabetic Retinopathy

Administration of a gap junction coupler reduces retinal vascular cell loss associated with diabetic retinopathy

Role of high glucose-induced lysyl oxidase overexpression on Ras activity in rat retinal endothelial cells

High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy

Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose–Induced Apoptosis

Intravitreal Aflibercept reduces the retinal vessel diameter in patients with diabetic macular edema

High Glucose-induced Changes in Mitochondrial Membrane Potential, Oxygen Consumption Rate, and Extracellular Acidification Promotes Mitochondrial Dysfunction in Retinal Endothelial and Müller Cells.

Fluorescence lifetime imaging microscopy on retinal microvascular endothelial cells under high glucose conditions

HG-induced upregulation of rab20 expression disrupts gap junctional intercellular communication and promotes retinal Müller cell (rMC) death

Differential effects of high glucose on connexin 43 hemichannels in compact versus sparsely grown retinal endothelial cells

High glucose-induced decrease in claudin-5 expression is facilitated by connexin 43 (Cx43) downregulation in retinal endothelial cells.

High Glucose Alters Cx43 Expression and Gap Junction Intercellular Communication in Retinal Müller Cells: Promotes Müller Cell and Pericyte Apoptosis

Effects of High Glucose-Induced Cx43 Downregulation on Claudin-5 Expression and Cell Monolayer Permeability in Retinal Endothelial Cells

Downregulation of Connexin 43 Expression and Gap Junction Intercellular Communication Promotes Apoptosis in Retinal Müller Cells

Direct downregulation of Connexin 43 expression promotes retinal vascular cell loss characteristic of diabetic retinopathy.

Effects of High Glucose-Induced Cx43 Downregulation on Occludin and ZO-1 Expression and Tight Junction Barrier Function in Retinal Endothelial Cells

High Glucose-Induced Connexin 43 (Cx43) Downregulation Modulates Rho/Rho kinase (ROCK) Signaling and Promotes Apoptosis in Retinal Endothelial Cells

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