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ARVO Annual Meeting Abstract June 2025

Composition of Meibum Determines its Thermotropic and Protective Properties: From Animal Models to Human Diseases

Igor A Butovich; Amber Wilkerson; Jadwiga Wojtowicz; Seher Yuksel

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6077.

ARVO Annual Meeting Abstract June 2025

The Impact of Aging on the Ocular Phenotype and Lipid Metabolism in the Meibomian Glands and Corneas of Soat1 -null mice

Amber Wilkerson; Seher Yuksel; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6071.

ARVO Annual Meeting Abstract June 2025

The Impact of Abnormal Meibum on the Ocular Surface Homeostasis in a Mouse Model of Meibomian Gland Dysfunction and Dry Eye

Rohma Zaidi; Amber Wilkerson; Seher Yuksel; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1562.

ARVO Annual Meeting Abstract June 2025

Decoding Meibogenesis: In Vivo Metabolism of Fatty Acids, Aldehydes, and Alcohols in Meibomian Glands

Seher Yuksel; Amber Wilkerson; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1893.

ARVO Annual Meeting Abstract June 2025

Accumulation of lipids in the aged lacrimal gland

Cintia S De Paiva; Sydney Krenz; Prashant Kumar; Kaitlin Karen Scholand; Zhiyuan Yu; Seher Yuksel; Helen P Makarenkova; Sarah F Hamm-Alvarez; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1892.

ARVO Annual Meeting Abstract June 2025

Cargo adapter protein Bicdl1 has an essential role in retinal health

Gizem Ulker-Yilmazer; Bogale Aredo; Dogan Can Kirman; Emily Turpin; Sangita Shrestha; Seher Yuksel; Tian Yu; Yu-guang He; Sara Ludwig; Eva Moresco; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3831.

Cornea July 2024

Physiological Effects of Soat1 Inactivation on Homeostasis of the Mouse Ocular Surface

PDF

Amber Wilkerson; Seher Yuksel; Riya Acharya; Igor A. Butovich
TAGS: cornea, mice, ocular surfaces
Invest. Ophthalmol. Vis. Sci.. 2024; 65(8):2. https://doi.org/10.1167/iovs.65.8.2

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Zinc-metallopeptidase Lmln deficiency induces subretinal microglia activation and retinal neurodegeneration

Dogan Can Kirman; Bogale Aredo; Yeshumenesh Zegeye; Sangita Shrestha; Emily Turpin; Gizem Ulker Yilmazer; Seher Yuksel; Yu-Guang He; Sara Ludwig; Eva Moresco; Bruce A. Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1658.

ARVO Annual Meeting Abstract June 2024

A cargo adaptor protein with an essential role in retinal health

Gizem Ulker Yilmazer; Bogale Aredo; Dogan Can Kirman; Emily Turpin; Sangita Shrestha; Seher Yuksel; Yu-Guang He; Sara Ludwig; Eva Moresco; Bruce A. Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6052.

ARVO Annual Meeting Abstract June 2023

The role of Lipe in lipid metabolism in the retina

Seher Yuksel; Rafael Ufret-Vincenty; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5454.

ARVO Annual Meeting Abstract June 2023

Sdr16c5 and Sdr16c6 genes control a bifurcation point between meibogenesis and sebogenesis in Meibomian glands of mice by suppressing a dormant biosynthetic pathway

Igor A Butovich; Amber Wilkerson; Kelly R. Goggans; Natalia Kedishvili; Seher Yuksel

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):166.

ARVO Annual Meeting Abstract June 2023

Herc3 mutations lead to prominent retinal microglial/macrophage activation and retinal degeneration.

Yeshumenesh Zegeye; Bogale Aredo; Seher Yuksel; Emily Turpin; Sangita Shrestha; Sara Ludwig; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1587.

ARVO Annual Meeting Abstract June 2023

Non-redundant role of a zinc-metallopeptidase in retinal homeostasis.

Dogan Can Kirman; Bogale Aredo; Yeshumenesh Zegeye; Seher Yuksel; Sangita Shrestha; Emily Turpin; Sara Ludwig; Bruce Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3877.

ARVO Annual Meeting Abstract June 2022

Novel association to retinal homeostasis identified for a gene involved in ubiquitination and proteasomal degradation.

Yeshumenesh Zegeye; Bogale Aredo; Seher Yuksel; Cynthia X. Zhao; Sara Ludwig; Miao Tang; Xiaohong Li; Bruce A. Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1963 – F0381.

ARVO Annual Meeting Abstract June 2022

Deletion of a cholesteryl ester hydrolase leads to a progressive retinal degeneration in mice

Seher Yuksel; Bogale Aredo; Yeshumenesh Zegeye; Cynthia X. Zhao; Miao Tang; Xiaohong Li; Laurent Gautron; Sara Ludwig; Igor A Butovich; Bruce A. Beutler; Rafael Ufret-Vincenty

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1952 – F0370.

ARVO Annual Meeting Abstract June 2021

Sterol O-acyltransferase 1 ( Soat1 ) is critical for cholesteryl ester production in mouse Meibomian glands

Amber Wilkerson; Seher Yuksel; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2048.

ARVO Annual Meeting Abstract June 2021

Establishing the role of dietary lipids in meibogenesis

Seher Yuksel; Amber Wilkerson; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):704.

ARVO Annual Meeting Abstract June 2020

The roles of Elovl3 and Elovl4 in lipid homeostasis in Harderian glands of mice

Seher Yuksel; Amber Wilkerson; Anne McMahon; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2622.

ARVO Annual Meeting Abstract June 2020

Inactivation of Awat2 in mice causes loss of wax ester lipids from meibum.

Anne McMahon; Seher Yuksel; Nita Bhat; Hai Pham; Amber Wilkerson; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2632.

ARVO Annual Meeting Abstract June 2020

Elongases of very long chain fatty acids-3 and 4 (ELOVL3 and ELOVL4) are essential for biosynthesis of meibum in mice

Amber Wilkerson; Nita Bhat; Seher Yuksel; Anne McMahon; Hai Pham; Igor A Butovich

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3227.

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