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Meeting Abstract (16)
Journal Articles (2)

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Investigative Ophthalmology & Visual Science (18)

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ARVO Annual Meeting Abstract (16)
Biochemistry and Molecular Biology (1)
Translational (1)

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Eye Anatomy and Disorders (2)
Genetics (2)
Retina (2)
Biochemistry and Molecular Biology (1)
Imaging (1)
Immunology and Microbiology (1)
Nanotechnology and Regenerative Medicine (1)
Retinal Imaging (1)
Translational Research (1)
Visual Neuroscience (1)

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bardet-biedl syndrome (2)
mice (2)
proteins (2)
antibodies (1)
chaperonin (1)
electroretinography (1)
eye (1)
gene therapy (1)
origin of life (1)
photoreceptors (1)

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ARVO Annual Meeting Abstract June 2021

Subretinal gene replacement rescues retinal phenotype in BBS10 mouse

Arlene V Drack; Angela Mahoney; Sajag Bhattarai; Sara Mayer; Jacintha Thomas; Poppy Datta; Ying Hsu; Janelle Garrison; Elise Heon; Charles Searby; Luk H Vandenberghe; Seongjin Seo; Val Sheffield

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1178. doi:

ARVO Annual Meeting Abstract June 2021

BBS10 knockout mouse exhibits developmental lack of cone function and recapitulates retinal degeneration.

Sara Mayer; Jacintha Thomas; Angela Mahoney; Sajag Bhattarai; Qihong Zhang; Elliot Stalter; Poppy Datta; Ying Hsu; Janelle Garrison; Charles Searby; Seongjin Seo; Val Sheffield; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3070. doi:

ARVO Annual Meeting Abstract June 2021

Differential requirement of NPHP1 for compartmentalized protein localization during photoreceptor outer segment development and maintenance

Seongjin Seo; Poppy Datta; J Thomas Cribbs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2223. doi:

ARVO Annual Meeting Abstract June 2020

Retinal degeneration in BBS10 mice is ameliorated by subretinal gene replacement

Arlene V Drack; Sajag Bhattarai; Jacintha Thomas; Elliot Stalter; Poppy Datta; ying Hsu; Janelle Garrison; Charles Searby; Luk H Vandenberghe; Elise Heon; Seongjin Seo; Val C Sheffield

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1914. doi:

ARVO Annual Meeting Abstract June 2020

Limited time window for retinal gene therapy of Bardet-Biedl syndrome

Seongjin Seo; Poppy Datta; Avri Ruffcorn

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2751. doi:

ARVO Annual Meeting Abstract July 2019

Effective arrest of retinal degeneration depends on the timing of gene restoration in a BBS17 mouse model

Poppy Datta; Brandon Hendrickson; Seongjin Seo

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3394. doi:

ARVO Annual Meeting Abstract July 2019

Loss of CEP290 causes accumulation of inner segment plasma membrane proteins in the outer segment

Seongjin Seo; Poppy Datta; Brandon Hendrickson

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3980. doi:

ARVO Annual Meeting Abstract July 2018

Determination of the optimal time window for gene replacement therapies for blindness using an inducible rescue mouse model of Bardet-Biedl Syndrome

Ying Hsu; Janelle Garrison; Gunhee Kim; Arlene V Drack; Darryl Nishimura; Seongjin Seo; Val C. Sheffield

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3962. doi:

ARVO Annual Meeting Abstract June 2017

Photoreceptors show age-dependent ability to regain function after restoration of target gene expression in mouse models of Bardet Biedl Syndrome

Ying Hsu; Janelle Garrison; Poppy Datta; Gunhee Kim; Darryl Nishimura; Charles C Searby; Seongjin Seo; Val Sheffield

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4542. doi:

ARVO Annual Meeting Abstract June 2015

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in BBS

Seongjin Seo; Poppy Datta; Chantal Allamargot; Joseph Hudson; Emily Andersen; Sajag Bhattarai; Arlene V Drack

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4644. doi:

Biochemistry and Molecular Biology June 2014

Essential Role of the Chaperonin CCT in Rod Outer Segment Biogenesis

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Satyabrata Sinha; Marycharmain Belcastro; Poppy Datta; Seongjin Seo; Maxim Sokolov
TAGS: chaperonin, origin of life, proteins, rod outer segments, rod photoreceptors, mice, western blotting, photoreceptors, bardet-biedl syndrome, antibodies
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3775-3785. doi: https://doi.org/10.1167/iovs.14-13889

ARVO Annual Meeting Abstract April 2014

Overcoming the overexpression toxicity of gene replacement therapy for Bardet Biedl Syndrome type 1

Arlene V Drack; Sajag Bhattarai; Seongjin Seo; Edwin M Stone; Val Sheffield; Robert Mullins; Budd A Tucker

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4378. doi:

Translational Research September 2013

Subretinal Gene Therapy of Mice With Bardet-Biedl Syndrome Type 1

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Seongjin Seo; Robert F. Mullins; Alina V. Dumitrescu; Sajag Bhattarai; Daniel Gratie; Kai Wang; Edwin M. Stone; Val Sheffield; Arlene V. Drack
TAGS: bardet-biedl syndrome, eye, gene therapy, mice, retina, electroretinography, spatial vectors, proteins, toxic effect
Invest. Ophthalmol. Vis. Sci.. 2013; 54(9):6118-6132. doi: https://doi.org/10.1167/iovs.13-11673

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2013

Interaction between CEP290 and BBSome genes is required for mediating cilia function in retina

Yan Zhang; Arlene Drack; Kevin Bugge; Charles Searby; Val Sheffield; Seongjin Seo

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3238. doi:

ARVO Annual Meeting Abstract June 2013

The Essential Role of CCT in Outer Segment Morphogenesis

Satyabrata Sinha; Marycharmain Belcastro; Seongjin Seo; Maxim Sokolov

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1227. doi:

ARVO Annual Meeting Abstract March 2012

Subretinal gene therapy in Bbs1 mice

Arlene V. Drack; Sajag Bhattarai; Seongjin Seo; Dan Gratie; Edwin M. Stone; Robert Mullins; Val Sheffield

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6566. doi:

ARVO Annual Meeting Abstract March 2012

Identification Of Proteins That Interact With TANK binding kinase 1 (TBK1)

John H. Fingert; Ben Roos; Frances Solivan-Timpe; Melissa Humbert; Seongjin Seo

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3848. doi:

ARVO Annual Meeting Abstract April 2011

Light Reduction, Neuroprotection, And Subretinal Gene Therapy In A Mouse Model Of Bardet Biedl Syndrome

Arlene V. Drack; Alina Dumitrescu; Robert Mullins; Seongjin Seo; Stewart Thompson; Megan Riker; Darryl Nishimura; Val Sheffield; Edwin M. Stone

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5464. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
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