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ARVO Annual Meeting Abstract June 2020

Diabetic Cornea: Effects of PM 2.5 and glycyrrhizin treatment.

Mallika Somayajulu; Sharon Ann McClellan; Sandamali Ekanayaka; Ahalya Pitchaikannu; Jena J Steinle; Linda D Hazlett

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4081. doi:

ARVO Annual Meeting Abstract June 2020

The miR-183/96/182 Cluster Regulates the Functions of Myeloid-derived Corneal Resident Innate Immune Cells

Shunbin Xu; Ardian Coku; Linda D Hazlett; Sharon Ann McClellan; Ahalya Pitchaikannu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4364. doi:

Immunology and Microbiology April 2020

Airborne Particulates Affect Corneal Homeostasis and Immunity

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Mallika Somayajulu; Sandamali Ekanayaka; Sharon A. McClellan; Denise Bessert; Ahalya Pitchaikannu; Kezhong Zhang; Linda D. Hazlett
TAGS: cornea, homeostasis, immunity, infections, mice, oxidative stress, hmgb1 protein, rna, messenger, reverse transcriptase polymerase chain reaction, molecule
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):23. doi: https://doi.org/10.1167/iovs.61.4.23

ARVO Annual Meeting Abstract July 2019

Is Glycyrrhizin the Magic Bullet for Multi-drug Resistance?

Linda D Hazlett; Sandamali Amarasingha Ekanayaka; Sharon A McClellan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4644. doi:

ARVO Annual Meeting Abstract July 2019

Particulates Mediate Corneal Oxidative Stress, Upregulate Innate Immunity, and Enhance Keratitis

Sandamali Amarasingha Ekanayaka; Sharon A McClellan; Ahalya Pitchaikannu; Rebecca Francis; Linda D Hazlett

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5181. doi:

ARVO Annual Meeting Abstract July 2019

The miR-183/96/182 cluster regulates corneal resident macrophages and early response to Pseudomonas aeruginosa infection

Shunbin Xu; Linda D Hazlett; Sharon A McClellan; chithra muraleedharan; Rebecca Francis; Liyue Zhang; Eric van Buren; Jessica Back

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5185. doi:

Immunology and Microbiology July 2019

Glycyrrhizin Use for Multi-Drug Resistant Pseudomonas aeruginosa : In Vitro and In Vivo Studies

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Linda D. Hazlett; Sandamali A. Ekanayaka; Sharon A. McClellan; Rebecca Francis
TAGS: ciprofloxacin, glycyrrhizic acid, keratitis, pseudomonas aeruginosa
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2978-2989. doi: https://doi.org/10.1167/iovs.19-27200

ARVO Annual Meeting Abstract July 2018

The miR-183/96/182 Cluster Modulates Pseudomonas aeruginosa -induced Keratitis Through Regulation of Innate Immune Cells

Shunbin Xu; Linda D Hazlett; Chithra Muraleedharan; Sharon A McClellan; Sandamali Amarasingha Ekanayaka; Ronald P Barrett

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1545. doi:

ARVO Annual Meeting Abstract June 2017

Topical glycyrrhizin is therapeutic for Pseudomonas aeruginosa keratitis.

Sandamali Amarasingha Ekanayaka; Sharon A McClellan; Ronald P Barrett; Linda Hazlett

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4290. doi:

ARVO Annual Meeting Abstract June 2017

HMGB1 antagonist, Box A reduces severity of Pseudomonas keratitis in susceptible C57BL/6 mice.

Sharon A McClellan; Linda Hazlett

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5761. doi:

ARVO Annual Meeting Abstract June 2017

Characterization of ocular clinical isolates and non-ocular multi-drug resistant strains of Pseudomonas aeruginosa and their susceptibility to killing by glycyrrhizin

Xudong Peng; Sandamali Amarasingha Ekanayaka; Sharon A McClellan; Alicia Eby; Linda Hazlett

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5762. doi:

Immunology and Microbiology October 2016

Glycyrrhizin Reduces HMGB1 and Bacterial Load in Pseudomonas aeruginosa Keratitis

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Sandamali A. Ekanayaka; Sharon A. McClellan; Ronald P. Barrett; Shikhil Kharotia; Linda D. Hazlett
TAGS: bone plates, glycyrrhizic acid, hmgb1 protein, infections, keratitis, mice, neutrophils, painful bladder syndrome, pseudomonas aeruginosa, reverse transcriptase polymerase chain reaction
Invest. Ophthalmol. Vis. Sci.. 2016; 57(13):5799-5809. doi: https://doi.org/10.1167/iovs.16-20103

ARVO Annual Meeting Abstract September 2016

Glycyrrhizin is protective against keratitis induced by P. aeruginosa and reduces both neutrophil infiltrate and plate count.

Sandamali Amarasingha Ekanayaka; Sharon A McClellan; Ronald P Barrett; Shikhil Kharotia; Linda D Hazlett

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Immunology and Microbiology April 2016

Inactivation of the miR-183/96/182 Cluster Decreases the Severity of Pseudomonas aeruginosa -Induced Keratitis

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Chithra K. Muraleedharan; Sharon A. McClellan; Ronald P. Barrett; Cui Li; Daniel Montenegro; Thomas Carion; Elizabeth Berger; Linda D. Hazlett; Shunbin Xu
TAGS: cornea, keratitis, mice, micrornas, pseudomonas aeruginosa, neuropeptides, infections, neurons
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1506-1517. doi: https://doi.org/10.1167/iovs.16-19134

Immunology and Microbiology December 2015

Thrombomodulin Protects Against Bacterial Keratitis, Is Anti-Inflammatory, but Not Angiogenic

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Sharon A. McClellan; Sandamali A. Ekanayaka; Cui Li; Xiaoyu Jiang; Ronald P. Barrett; Linda D. Hazlett
TAGS: angiogenesis, anti-inflammatory agents, bacterial keratitis, cornea, infections, keratitis, mice, painful bladder syndrome, proteins, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8091-8100. doi: https://doi.org/10.1167/iovs.15-18393

ARVO Annual Meeting Abstract June 2015

Thrombomodulin protects against bacterial keratitis and is not angiogenic.

Linda D Hazlett; Sharon A McClellan; Cui Li

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4053. doi:

ARVO Annual Meeting Abstract June 2015

Inactivation of miR-183/96/182 Reduces Severity of Pseudomonas aeruginosa Infection of the Cornea

Shunbin Xu; Linda D Hazlett; Elizabeth A Berger; Susmit Suvas; Cui Li; Chithra Muraleedharan; Ronald Barrett; Sharon A McClellan; Thomas Carion; Daniel Montenegro

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):943. doi:

Immunology and Microbiology October 2014

Interleukin 17 Regulates Mer Tyrosine Kinase–Positive Cells in Pseudomonas aeruginosa Keratitis

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Cui Li; Sharon A. McClellan; Ronald Barrett; Linda D. Hazlett
TAGS: infections, interleukin-17, mice, mice, inbred c57bl, cornea, keratitis, mice, inbred balb c, protein tyrosine kinase, neutralizing antibodies
Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6886-6900. doi: https://doi.org/10.1167/iovs.14-14522

ARVO Annual Meeting Abstract April 2014

Hmgb1: A target for treatment of Pseudomonas aeruginosa keratitis

Linda D Hazlett; Xiaoyu Jiang; Sharon A McClellan; Ronald P Barrett

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1688. doi:

ARVO Annual Meeting Abstract April 2014

Neutrophil Transdifferentiation as a Factor of Disease Pathogenesis

Elizabeth A Berger; Cody R McWhirter; Sharon A McClellan; Linda D Hazlett; Norbert Wolf

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6272. doi:

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Diabetic Cornea: Effects of PM 2.5 and glycyrrhizin treatment.

The miR-183/96/182 Cluster Regulates the Functions of Myeloid-derived Corneal Resident Innate Immune Cells

Airborne Particulates Affect Corneal Homeostasis and Immunity

Is Glycyrrhizin the Magic Bullet for Multi-drug Resistance?

Particulates Mediate Corneal Oxidative Stress, Upregulate Innate Immunity, and Enhance Keratitis

The miR-183/96/182 cluster regulates corneal resident macrophages and early response to Pseudomonas aeruginosa infection

Glycyrrhizin Use for Multi-Drug Resistant Pseudomonas aeruginosa : In Vitro and In Vivo Studies

The miR-183/96/182 Cluster Modulates Pseudomonas aeruginosa -induced Keratitis Through Regulation of Innate Immune Cells

Topical glycyrrhizin is therapeutic for Pseudomonas aeruginosa keratitis.

HMGB1 antagonist, Box A reduces severity of Pseudomonas keratitis in susceptible C57BL/6 mice.

Characterization of ocular clinical isolates and non-ocular multi-drug resistant strains of Pseudomonas aeruginosa and their susceptibility to killing by glycyrrhizin

Glycyrrhizin Reduces HMGB1 and Bacterial Load in Pseudomonas aeruginosa Keratitis

Glycyrrhizin is protective against keratitis induced by P. aeruginosa and reduces both neutrophil infiltrate and plate count.

Inactivation of the miR-183/96/182 Cluster Decreases the Severity of Pseudomonas aeruginosa -Induced Keratitis

Thrombomodulin Protects Against Bacterial Keratitis, Is Anti-Inflammatory, but Not Angiogenic

Thrombomodulin protects against bacterial keratitis and is not angiogenic.

Inactivation of miR-183/96/182 Reduces Severity of Pseudomonas aeruginosa Infection of the Cornea

Interleukin 17 Regulates Mer Tyrosine Kinase–Positive Cells in Pseudomonas aeruginosa Keratitis

Hmgb1: A target for treatment of Pseudomonas aeruginosa keratitis

Neutrophil Transdifferentiation as a Factor of Disease Pathogenesis

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