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Retina May 2025

Muscone Attenuates Uveitis Through the PI3K/AKT Signaling Pathway

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Xianyang Liu; Hangjia Zuo; Chao Wu; Na Li; Qian Zhou; Fan Cao; Baorui Chu; Shuhao Zeng; Hui Feng; Yakun Wang; Fengyang Lei; Ke Hu; Shengping Hou
TAGS: akt signaling pathway, mice, phosphoinositide 3-kinase, proteins, uveitis, inflammation, retina
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):21. https://doi.org/10.1167/iovs.66.5.21

Includes: Supplemental Content

Physiology and Pharmacology May 2023

Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization

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Nan Shu; Zhi Zhang; Xiaotang Wang; Ruonan Li; Wanqian Li; Xianyang Liu; Qi Zhang; Zhengxuan Jiang; Liming Tao; Li Zhang; Shengping Hou
TAGS: autoimmunity, microglia, uveitis, toll-like receptor 4, western blotting, myd88 gene, proteins, inflammation
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):21. https://doi.org/10.1167/iovs.64.5.21

Includes: Supplemental Content

Retina July 2022

LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia

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Chenyang Zhao; Yusen Liu; Jiayu Meng; Xiaotang Wang; Xianyang Liu; Wanqian Li; Qian Zhou; Junjie Xiang; Na Li; Shengping Hou
TAGS: 1-phosphatidylinositol 3-kinase, akt signaling pathway, angiogenesis, hypoxia, microglia
Invest. Ophthalmol. Vis. Sci.. 2022; 63(8):25. https://doi.org/10.1167/iovs.63.8.25

Genetics November 2019

Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease

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Jian Qi; Liping Du; Jing Deng; Yang Qin; Guannan Su; Shengping Hou; Meng Lv; Qi Zhang; Aize Kijlstra; Peizeng Yang
TAGS: cytokine, disease susceptibility, genome-wide association study, genotype, rna, messenger, rna, untranslated, single nucleotide polymorphism, uveomeningoencephalitic syndrome, chief complaint
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4820-4829. https://doi.org/10.1167/iovs.19-27708

Genetics February 2018

Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease

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Yingying Yue; Jun Zhang; Lu Yang; Shengyun Liu; Jian Qi; Qingfeng Cao; Chunjiang Zhou; Yao Wang; Aize Kijlstra; Peizeng Yang; Shengping Hou
TAGS: ankylosing spondylitis, behcet syndrome, genotype, il12b gene, polymorphism, single nucleotide polymorphism, uveitis, uveomeningoencephalitic syndrome, cytokine, uvea
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):1158-1166. https://doi.org/10.1167/iovs.17-23247

Includes: Supplemental Content

Genetics April 2017

miRNA Copy Number Variants Confer Susceptibility to Acute Anterior Uveitis With or Without Ankylosing Spondylitis

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Lu Yang; Liping Du; Yingying Yue; Yike Huang; Qingyun Zhou; Shuang Cao; Jian Qi; Liang Liang; Lili Wu; Chaokui Wang; Zi Ye; Yuan Tian; Aize Kijlstra; Shengping Hou; Peizeng Yang
TAGS: ankylosing spondylitis, copy number polymorphism, disease susceptibility, micrornas, uveitis, anterior, cytokine, interleukin-6, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):1991-2001. https://doi.org/10.1167/iovs.16-21047

Includes: Supplemental Content

Genetics April 2016

Association of T-Bet, GATA-3, RORC, and FOXP3 Copy Number Variations With Acute Anterior Uveitis With or Without Ankylosing Spondylitis in Chinese Han

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Lin Bai; Yunjia Liu; Shengping Hou; Dan Liao; Aize Kijlstra; Peizeng Yang
TAGS: ankylosing spondylitis, chinese people, foxp3 gene, gata3 gene, uveitis, anterior
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1847-1852. https://doi.org/10.1167/iovs.15-17960

Genetics July 2015

Complement C5 Gene Confers Risk for Acute Anterior Uveitis

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Dengfeng Xu; Shengping Hou; Yanni Jiang; Jun Zhang; Shuang Cao; Dike Zhang; Le Luo; Aize Kijlstra; Peizeng Yang
TAGS: complement component c5, cytokine, genes, genotype, interleukin-17, polymorphism, rna, messenger, single nucleotide polymorphism, uveitis, anterior, proteins
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4954-4960. https://doi.org/10.1167/iovs.15-16645

Includes: Supplemental Content

Genetics July 2015

Association of Genetic Variations in TNFSF15 With Acute Anterior Uveitis in Chinese Han

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Hua Li; Shengping Hou; Hongsong Yu; Minming Zheng; Lijun Zhang; Jun Zhang; Qi Zhang; Qingfeng Cao; Gangxiang Yuan; Aize Kijlstra; Peizeng Yang
TAGS: chinese (other dialects), chinese people, genetics, tnfsf15 gene, uveitis, anterior, genotype, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4605-4610. https://doi.org/10.1167/iovs.15-16896

Includes: Supplemental Content

Genetics March 2015

Association Between Copy Number Variations of TLR7 and Ocular Behçet's Disease in a Chinese Han Population

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Jing Fang; Lu Chen; Jihong Tang; Shengping Hou; Dan Liao; Zi Ye; Chaokui Wang; Qinfeng Cao; Aize Kijlstra; Peizeng Yang
TAGS: behcet syndrome, chinese people, gene dosage, genes, rna, messenger, uveomeningoencephalitic syndrome, agonists
Invest. Ophthalmol. Vis. Sci.. 2015; 56(3):1517-1523. https://doi.org/10.1167/iovs.14-15030

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Copy Number Variations in IL17F and IL23A Genes Associated with Susceptibility to Uveitis Associated with Systemic Involvement but not with Uveitis alone in Chinese Han Population

Peizeng Yang; Shengping Hou; Aize Kijlstra

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1874.

Genetics December 2013

Association of TLR2 Gene Polymorphisms With Ocular Behçet's Disease in a Chinese Han Population

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Jing Fang; Ranran Hu; Shengping Hou; Zi Ye; Qin Xiang; Jian Qi; Yan Zhou; Aize Kijlstra; Peizeng Yang
TAGS: behcet syndrome, chinese (other dialects), genes, genotype, polymorphism, single nucleotide polymorphism, toll-like receptor 2, chinese people, disease susceptibility, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2013; 54(13):8384-8392. https://doi.org/10.1167/iovs.13-12878

Includes: Supplemental Content

Immunology and Microbiology November 2013

MIF Gene Polymorphisms Confer Susceptibility to Vogt-Koyanagi-Harada Syndrome in a Han Chinese Population

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Chunxia Zhang; Shouli Liu; Shengping Hou; Bo Lei; Xiuyun Zheng; Xiang Xiao; Aize Kijlstra; Peizeng Yang
TAGS: chinese (other dialects), chinese people, disease susceptibility, genes, polymorphism, uveomeningoencephalitic syndrome
Invest. Ophthalmol. Vis. Sci.. 2013; 54(12):7734-7738. https://doi.org/10.1167/iovs.13-12187

Genetics May 2013

JAK1 , but Not JAK2 and STAT3 , Confers Susceptibility to Vogt–Koyanagi–Harada (VKH) Syndrome in a Han Chinese Population

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Ke Hu; Shengping Hou; Fuzhen Li; Qin Xiang; Aize Kijlstra; Peizeng Yang
TAGS: chinese (other dialects), chinese people, disease susceptibility, stat3 protein, syndrome, uveomeningoencephalitic syndrome, genes, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2013; 54(5):3360-3365. https://doi.org/10.1167/iovs.13-11615

Genetics January 2012

JAK2 and STAT3 Polymorphisms in a Han Chinese Population with Behçet's Disease

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Ke Hu; Shengping Hou; Zhengxuan Jiang; Aize Kijlstra; Peizeng Yang
TAGS: behcet syndrome, chinese (other dialects), chinese people, polymorphism, stat3 protein
Invest. Ophthalmol. Vis. Sci.. 2012; 53(1):538-541. https://doi.org/10.1167/iovs.11-8440

Immunology and Microbiology September 2011

Elevated Serum Osteopontin Levels and Genetic Polymorphisms of Osteopontin Are Associated with Vogt-Koyanagi-Harada Disease

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Mingliang Chu; Peizeng Yang; Ranran Hu; Shengping Hou; Fuzhen Li; Yuanyuan Chen; Aize Kijlstra
TAGS: cytokine, osteopontin, polymorphism, uveomeningoencephalitic syndrome, interleukin-17, antibodies, inflammatory disorders, cd28 antigens, t-lymphocytes, genotype
Invest. Ophthalmol. Vis. Sci.. 2011; 52(10):7084-7089. https://doi.org/10.1167/iovs.11-7539

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

A Variant Of UBAC2 In Behçet’s Disease

Shengping Hou; Qinmeng Shu; Peizeng Yang; Zhengxuan Jiang; Yuanyuan Chen; Fuzhen Li; Kijlstra Aize

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3297.

ARVO Annual Meeting Abstract April 2011

CD4+ T Cells In Vogt-koyanagi-harada Disease Show A Decreased Stimulation Of IL-27 Expression By Dendritic Cells

Peizeng Yang; Chaokui Wang; Lichun Tian; Ju Shao; Fuzhen Li; Yuan Tian; Lei Bo; Shengping Hou; Kijlstra Aize

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6638.

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Muscone Attenuates Uveitis Through the PI3K/AKT Signaling Pathway

Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization

LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia

Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease

Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease

miRNA Copy Number Variants Confer Susceptibility to Acute Anterior Uveitis With or Without Ankylosing Spondylitis

Association of T-Bet, GATA-3, RORC, and FOXP3 Copy Number Variations With Acute Anterior Uveitis With or Without Ankylosing Spondylitis in Chinese Han

Complement C5 Gene Confers Risk for Acute Anterior Uveitis

Association of Genetic Variations in TNFSF15 With Acute Anterior Uveitis in Chinese Han

Association Between Copy Number Variations of TLR7 and Ocular Behçet's Disease in a Chinese Han Population

Copy Number Variations in IL17F and IL23A Genes Associated with Susceptibility to Uveitis Associated with Systemic Involvement but not with Uveitis alone in Chinese Han Population

Association of TLR2 Gene Polymorphisms With Ocular Behçet's Disease in a Chinese Han Population

MIF Gene Polymorphisms Confer Susceptibility to Vogt-Koyanagi-Harada Syndrome in a Han Chinese Population

JAK1 , but Not JAK2 and STAT3 , Confers Susceptibility to Vogt–Koyanagi–Harada (VKH) Syndrome in a Han Chinese Population

JAK2 and STAT3 Polymorphisms in a Han Chinese Population with Behçet's Disease

Elevated Serum Osteopontin Levels and Genetic Polymorphisms of Osteopontin Are Associated with Vogt-Koyanagi-Harada Disease

A Variant Of UBAC2 In Behçet’s Disease

CD4+ T Cells In Vogt-koyanagi-harada Disease Show A Decreased Stimulation Of IL-27 Expression By Dendritic Cells

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