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ARVO Annual Meeting Abstract June 2017

The effects of Pigment Epithelium-Derived Factor on Epithelial-to-mesenchymal transition of the retinal pigment epithelium induced by TGF-β.

Sha Ouyang; Shikun He; Chirstine Spee; David R Hinton

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5977. doi:

Retinal Cell Biology August 2015

Inhibition of DNA Methylation and Methyl-CpG-Binding Protein 2 Suppresses RPE Transdifferentiation: Relevance to Proliferative Vitreoretinopathy

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Shikun He; Ernesto Barron; Keijiro Ishikawa; Hossein Nazari Khanamiri; Chris Spee; Peng Zhou; Satoru Kase; Zhuoshi Wang; Laurie Diane Dustin; David R. Hinton
TAGS: cell transdifferentiation, deoxycytidine, dna methylation, proteins, vitreoretinopathy, proliferative, tissue membrane
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5579-5589. doi: https://doi.org/10.1167/iovs.14-16258

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Resveratrol inhibits TGF-β induced RPE epithelial-to-mesenchymal transition through activation of Sirtuin1

Shikun He; Keijiro Ishikawa; Hossein Nazari; Christine Spee; David R Hinton

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):197. doi:

ARVO Annual Meeting Abstract April 2014

The effects of SIRT1 on hypoxia induced by cobalt chloride in human fetal retinal pigment epithelial cells

Huiming Zhang; Shikun He; Christine Spee; David R Hinton

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):385. doi:

ARVO Annual Meeting Abstract April 2014

The inhibition of laser induced choroidal neovascularization in rats by soluble EphB4-HSA

Shikun He; Huiming Zhang; Christine Spee; Reen Liu; Valery Krasnoperov; Parkash Gill; David R Hinton

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4947. doi:

ARVO Annual Meeting Abstract April 2014

Angiofibrotic Response to Bevacizumab on Fibrovascular Membranes in Proliferative Diabetic Retinopathy

Chunhua Jiao; Christine Spee; Shikun He; Robert Mullins; Dean Eliott; David R Hinton; Elliott H Sohn

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5821. doi:

ARVO Annual Meeting Abstract June 2013

The role of VEGFR-3 in the pathogenesis of choroidal neovascularization in age-related macular degeneration

Takeshi Yoshida; Shikun He; Mizuki Kitamura; Christine Spee; Stephen Ryan; David Hinton

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):334. doi:

ARVO Annual Meeting Abstract March 2012

The Expression Of Phosphorylated MeCP2 Is Altered In Proliferative Diabetic Retinopathy Membranes

Shikun He; C. Spee; T. Yoshida; S. J. Ryan; D. R. Hinton

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2439. doi:

ARVO Annual Meeting Abstract March 2012

Epigenetic Regulation of Choroidal Neovascularization

Nymph Chan; Shikun He; Stephen J. Ryan, Jr.; David R. Hinton

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3019. doi:

ARVO Annual Meeting Abstract March 2012

The Role Of Sirt1 In The Pathogenesis Of Dry Age-related Macular Degeneration

Takeshi Yoshida; Shikun He; Christine Spee; Stephen J. Ryan, Jr.; David R. Hinton

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3193. doi:

ARVO Annual Meeting Abstract March 2012

Differential Expression of MeCP2 and its Regulation by miR132 in Human RPE Cells

Parameswaran G. Sreekumar; Shikun He; Christine Spee; Stephen J. Ryan; Rama Natarajan; David R. Hinton

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4774. doi:

ARVO Annual Meeting Abstract March 2012

Angiofibrotic Response To VEGF Inhibition In Membranes Extracted During Diabetic Vitrectomy: Results Of A Randomized, Controlled, Translational Study

Elliott H. Sohn; Christine Spee; Shikun He; Dean Eliott; David R. Hinton

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):360. doi:

Retinal Cell Biology July 2011

Regulation of Fibronectin-EDA through CTGF Domain–Specific Interactions with TGFβ2 and Its Receptor TGFβRII

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Rima Khankan; Noelynn Oliver; Shikun He; Stephen J. Ryan; David R. Hinton
TAGS: connective tissue growth factor, retinal pigment cell, proteins, fibronectins
Invest. Ophthalmol. Vis. Sci.. 2011; 52(8):5068-5078. doi: https://doi.org/10.1167/iovs.11-7191

ARVO Annual Meeting Abstract April 2011

αB-crystallin Expression is Regulated by Histone Deacetylase Inhibitor in Human Fetal Retinal Pigment Epithelial Cells

Mizuki Kitamura; Shikun He; Takeshi Yoshida; Christine Spee; Stephen J. Ryan; David R. Hinton

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):868. doi:

ARVO Annual Meeting Abstract April 2011

The Expression Of PPAR-gamma In RPE Cells Is Epigenetically Regulated By DNA Methylation

Shikun He; Nymph Chan; Jing Xu; Peng Zhou; S. J. Ryan; David. R. Hinton

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):898. doi:

ARVO Annual Meeting Abstract April 2011

Randomized, Double-Masked, Controlled Translational Investigation Of Bevacizumab For Retinal Detachment Due To Proliferative Diabetic Retinopathy

Elliott H. Sohn; Dean Eliott; Shikun He; Leo Kim; Hani Salehi-Had; Michael Javaheri; Chris Spee; Laurie Dustin; David Hinton

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):981. doi:

ARVO Annual Meeting Abstract April 2011

Choroidal Neovascularization is Regulated by Histone Acetylation

Nymph Chan; Shikun He; Christine Spee; Stephen Ryan; David Hinton

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1785. doi:

ARVO Annual Meeting Abstract April 2011

Histone Acetylation is Regulated by αB-crystallin in Retina

Takeshi Yoshida; Mizuki Kitamura; Shikun He; Christine Spee; Stephen J. Ryan; David R. Hinton

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4787. doi:

Retinal Cell Biology January 2010

Soluble EphB4 Inhibition of PDGF-Induced RPE Migration In Vitro

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Shikun He; S. Ram Kumar; Peng Zhou; Valery Krasnoperov; Stephen J. Ryan; Parkash S. Gill; David R. Hinton
TAGS: platelet-derived growth factor, retinal pigment cell, phosphorylation, retinal pigment epithelium, mitogen-activated protein kinases
Invest. Ophthalmol. Vis. Sci.. 2010; 51(1):543-552. doi: https://doi.org/10.1167/iovs.09-3475

Retina September 2008

Connective Tissue Growth Factor as a Mediator of Intraocular Fibrosis

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Shikun He; Youxin Chen; Rima Khankan; Ernesto Barron; Richard Burton; DanHong Zhu; Stephen J. Ryan; Noelynn Oliver; David R. Hinton
TAGS: connective tissue growth factor, fibrosis, oryctolagus cuniculus
Invest. Ophthalmol. Vis. Sci.. 2008; 49(9):4078-4088. doi: https://doi.org/10.1167/iovs.07-1302

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The effects of Pigment Epithelium-Derived Factor on Epithelial-to-mesenchymal transition of the retinal pigment epithelium induced by TGF-β.

Inhibition of DNA Methylation and Methyl-CpG-Binding Protein 2 Suppresses RPE Transdifferentiation: Relevance to Proliferative Vitreoretinopathy

Resveratrol inhibits TGF-β induced RPE epithelial-to-mesenchymal transition through activation of Sirtuin1

The effects of SIRT1 on hypoxia induced by cobalt chloride in human fetal retinal pigment epithelial cells

The inhibition of laser induced choroidal neovascularization in rats by soluble EphB4-HSA

Angiofibrotic Response to Bevacizumab on Fibrovascular Membranes in Proliferative Diabetic Retinopathy

The role of VEGFR-3 in the pathogenesis of choroidal neovascularization in age-related macular degeneration

The Expression Of Phosphorylated MeCP2 Is Altered In Proliferative Diabetic Retinopathy Membranes

Epigenetic Regulation of Choroidal Neovascularization

The Role Of Sirt1 In The Pathogenesis Of Dry Age-related Macular Degeneration

Differential Expression of MeCP2 and its Regulation by miR132 in Human RPE Cells

Angiofibrotic Response To VEGF Inhibition In Membranes Extracted During Diabetic Vitrectomy: Results Of A Randomized, Controlled, Translational Study

Regulation of Fibronectin-EDA through CTGF Domain–Specific Interactions with TGFβ2 and Its Receptor TGFβRII

αB-crystallin Expression is Regulated by Histone Deacetylase Inhibitor in Human Fetal Retinal Pigment Epithelial Cells

The Expression Of PPAR-gamma In RPE Cells Is Epigenetically Regulated By DNA Methylation

Randomized, Double-Masked, Controlled Translational Investigation Of Bevacizumab For Retinal Detachment Due To Proliferative Diabetic Retinopathy

Choroidal Neovascularization is Regulated by Histone Acetylation

Histone Acetylation is Regulated by αB-crystallin in Retina

Soluble EphB4 Inhibition of PDGF-Induced RPE Migration In Vitro

Connective Tissue Growth Factor as a Mediator of Intraocular Fibrosis

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