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ARVO Annual Meeting Abstract June 2020

The effect of stimulation with pro-inflammatory cytokines on uveal choroidal melanocytes

Bjørg Skjøth Lunding; Maja Søberg Udsen; Simon J Clark; Tina Jehs; Julie Friis Weber; Mogens Holst Nissen

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2234. doi:

ARVO Annual Meeting Abstract June 2020

Complement expression and immunolocalisation studies of the RPE/choroid complex provide evidence for Bruch’s membrane degradation in early AMD

Paul N Bishop; Selina McHarg; Fan He; Nadhim Bayatti; Richard Unwin; Anthony J Day; Simon J Clark

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3118. doi:

ARVO Annual Meeting Abstract July 2019

Genetic risk of AMD at both the CFH and ARMS2/HTRA1 loci is associated with increased protease expression and activity in human Bruch’s membrane/inner choroid.

Paul N Bishop; Selina McHarg; Nadhim Bayatti; Rahat Perveen; Graeme Black; Anthony J Day; Andrew Dowsey; Simon J Clark; Richard J Unwin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2814. doi:

ARVO Annual Meeting Abstract July 2019

Factor H-Related Protein 4 (FHR-4) drives complement dysregulation in age-related macular degeneration

Valentina Cipriani; Laura Lorés de Motta; Fan He; Dina Fathalla; Selina McHarg; Nadhim Bayatti; Ilhan Erkin Acar; Carel C B Hoyng; Sascha Fauser; Anthony Moore; John RW Yates; Paul Morgan; Eiko de Jong; Anneke I Den Hollander; Paul N Bishop; Simon J Clark

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3870. doi:

ARVO Annual Meeting Abstract July 2019

Interactions between Uveal Choroidal Melanocytes and Monocytes in vitro

Maja Søberg Udsen; Annie L Ingerslev; Tina Jehs; Carsten Faber; Simon J Clark; Mogens Holst Nissen

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4327. doi:

ARVO Annual Meeting Abstract June 2017

Expression of complement and other inflammatory pathway genes is co-ordinated in the human RPE cell transcriptome.

Paul N Bishop; Selina McHarg; Nicole Brace; Alexander W.W. Langford-Smith; Richard Unwin; Rahat Perveen; Graeme C. Black; Anthony Day; Simon John Clark

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3378. doi:

Immunology and Microbiology December 2016

Induction of Chemokine Secretion and Monocyte Migration by Human Choroidal Melanocytes in Response to Proinflammatory Cytokines

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Tina Jehs; Carsten Faber; Maja S. Udsen; Martine J. Jager; Simon J. Clark; Mogens H. Nissen
TAGS: bodily secretions, chemokines, cytokine, donors, melanocytes, monocytes, tumor necrosis factors, t-lymphocytes, proteins, monocyte chemoattractant protein-1
Invest. Ophthalmol. Vis. Sci.. 2016; 57(15):6568-6579. doi: https://doi.org/10.1167/iovs.15-18524

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

The expression of complement genes by retinal pigment epithelial cells from donors with and without AMD

Selina McHarg; Nicole Brace; Rahat Perveen; Graeme C.M. Black; Richard Unwin; Gregory S Hageman; Anthony John Day; Simon John Clark; Paul N Bishop

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2638. doi:

ARVO Annual Meeting Abstract September 2016

Permeability of Bruch’s membrane to complement proteins: Implications for translational medicine in AMD

Simon John Clark; Selina McHarg; Nicole Brace; Paul N Bishop

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Age-related accumulation of metal ions in Bruch’s membrane: implications for AMD

Anthony John Day; Alex Langford-Smith; Viranga Tilakaratna; Larisa Logunova; Paul Lythgoe; Simon John Clark; Paul N Bishop

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6559. doi:

Anatomy and Pathology/Oncology August 2014

Age-Dependent Changes in Heparan Sulfate in Human Bruch's Membrane: Implications for Age-Related Macular Degeneration

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Tiarnan D. L. Keenan; Claire E. Pickford; Rebecca J. Holley; Simon J. Clark; Wanchang Lin; Andrew W. Dowsey; Catherine L. Merry; Anthony J. Day; Paul N. Bishop
TAGS: age-related macular degeneration, biological response modifiers, heparitin sulfate, bruch's basal membrane, disaccharides, body tissue, donors
Invest. Ophthalmol. Vis. Sci.. 2014; 55(8):5370-5379. doi: https://doi.org/10.1167/iovs.14-14126

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

The role of complement factor H-like and factor H-related proteins in age-related macular degeneration

Simon John Clark; Richard Unwin; Anne N White; David C Briggs; Paul N Bishop

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1325. doi:

Anatomy and Pathology/Oncology November 2012

Mapping the Differential Distribution of Proteoglycan Core Proteins in the Adult Human Retina, Choroid, and Sclera

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Tiarnan D. L. Keenan; Simon J. Clark; Richard D. Unwin; Liam A. Ridge; Anthony J. Day; Paul N. Bishop
TAGS: body tissue, choroid, proteins, proteoglycan, retina, sclera, adult, bruch's basal membrane
Invest. Ophthalmol. Vis. Sci.. 2012; 53(12):7528-7538. doi: https://doi.org/10.1167/iovs.12-10797

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Mapping The Differential Distribution Of Proteoglycan Core Proteins In The Human Retina And Choroid

Tiarnan D. Keenan; Simon J. Clark; Richard D. Unwin; Liam A. Ridge; Anthony J. Day; Paul N. Bishop

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1589. doi:

ARVO Annual Meeting Abstract March 2012

The Disease-associated Glycosaminoglycan-binding (Y402H) Region Of Complement Factor H Mediates Host Recognition Of Human Bruch’S Membrane And Choroid: Implications Of Age-related Macular Degeneration

Simon J. Clark; Liam Ridge; Andrew P. Herbert; Svetlana Hakobyan; Barbara Mulloy; Reinhard Wurzner; Paul Morgan; Dusan Uhrin; Paul N. Bishop; Anthony J. Day

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2712. doi:

Biochemistry and Molecular Biology August 2011

Mapping the Differential Distribution of Glycosaminoglycans in the Adult Human Retina, Choroid, and Sclera

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Simon J. Clark; Tiarnan D. L. Keenan; Helen L. Fielder; Lisa J. Collinson; Rebecca J. Holley; Catherine L. R. Merry; Toin H. van Kuppevelt; Anthony J. Day; Paul N. Bishop
TAGS: adult, antibodies, body tissue, choroid, glycosaminoglycans, retina, sclera, proteins
Invest. Ophthalmol. Vis. Sci.. 2011; 52(9):6511-6521. doi: https://doi.org/10.1167/iovs.11-7909

ARVO Annual Meeting Abstract April 2011

Proteoglycomic Analysis Of The Human Retina

Tiarnan D. Keenan; Richard D. Unwin; Simon J. Clark; Anthony J. Day; Paul N. Bishop

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3350. doi:

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The effect of stimulation with pro-inflammatory cytokines on uveal choroidal melanocytes

Complement expression and immunolocalisation studies of the RPE/choroid complex provide evidence for Bruch’s membrane degradation in early AMD

Genetic risk of AMD at both the CFH and ARMS2/HTRA1 loci is associated with increased protease expression and activity in human Bruch’s membrane/inner choroid.

Factor H-Related Protein 4 (FHR-4) drives complement dysregulation in age-related macular degeneration

Interactions between Uveal Choroidal Melanocytes and Monocytes in vitro

Expression of complement and other inflammatory pathway genes is co-ordinated in the human RPE cell transcriptome.

Induction of Chemokine Secretion and Monocyte Migration by Human Choroidal Melanocytes in Response to Proinflammatory Cytokines

The expression of complement genes by retinal pigment epithelial cells from donors with and without AMD

Permeability of Bruch’s membrane to complement proteins: Implications for translational medicine in AMD

Age-related accumulation of metal ions in Bruch’s membrane: implications for AMD

Age-Dependent Changes in Heparan Sulfate in Human Bruch's Membrane: Implications for Age-Related Macular Degeneration

The role of complement factor H-like and factor H-related proteins in age-related macular degeneration

Mapping the Differential Distribution of Proteoglycan Core Proteins in the Adult Human Retina, Choroid, and Sclera

Mapping The Differential Distribution Of Proteoglycan Core Proteins In The Human Retina And Choroid

The Disease-associated Glycosaminoglycan-binding (Y402H) Region Of Complement Factor H Mediates Host Recognition Of Human Bruch’S Membrane And Choroid: Implications Of Age-related Macular Degeneration

Mapping the Differential Distribution of Glycosaminoglycans in the Adult Human Retina, Choroid, and Sclera

Proteoglycomic Analysis Of The Human Retina

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