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ARVO Annual Meeting Abstract June 2020

Mechanical strain results causes cytoskeletal remodeling and cellular elastinopathy in primary optic nerve head astrocytes

Simon Kaja; Evan B Stubbs; Claire H Mitchell; Anita K. Ghosh

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):992. doi:

ARVO Annual Meeting Abstract June 2020

Aspirin and its metabolite, hippuric acid, increase VEGF Expression in human retinal pigment epithelium cells

Johana Santa Maria; Maleen Cabe; Omer Iqbal; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2289. doi:

ARVO Annual Meeting Abstract June 2020

Subconjunctival Chemotherapeutic Delivery by Fibrin Sealant in the Treatment of Retinoblastoma

Chris Himes; Evan B Stubbs; Tim Fulghum; Shawn Bairstow; Simon Kaja; Jawed Fareed

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2815. doi:

ARVO Annual Meeting Abstract June 2020

Xanthohumol protects corneal epithelial cells in experimental models for dry-eye disease

Anita K. Ghosh; Rubina Thapa; Harsh Nilesh Hariani; Agne Ziniauskaite; Samatha Ankireddy; Karoline A Orloff; Jenni J. Hakkarainen; Giedrius Kalesnykas; Kelly Langert; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3257. doi:

ARVO Annual Meeting Abstract June 2020

Automated quantification of CNV volume using deep learning AI algorithm

Maria Vähätupa; Symantas Ragauskas; Agne Ziniauskaite; Anna Knuuttila; Hanna-Kaisa Sihvo; Mikael Jääskeläinen; Simon Kaja; Giedrius Kalesnykas; Marc Cerrada-Gimenez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4194. doi:

ARVO Annual Meeting Abstract June 2020

Comparative efficacy of bevacizumab and aflibercept in the rabbit DL-AAA model of chronic retinal neovascularization

Robertas Cesna; Tomas Paulauskas; Kernius Mickevicius; Donatas Neverauskas; Inesa Lelyte; Simon Kaja; Giedrius Kalesnykas; Symantas Ragauskas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5391. doi:

ARVO Annual Meeting Abstract June 2020

Characterization of VEGF-induced retinal neovascularization in Dutch Belted rabbits using in vivo imaging.

Donatas Neverauskas; Kernius Mickevičius; Simon Kaja; Giedrius Kalesnykas; Symantas Ragauskas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5399. doi:

Glaucoma August 2019

Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells

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Vidhya R. Rao; Jonathan D. Lautz; Simon Kaja; Eileen M. Foecking; Emőke Lukács; Evan B. Stubbs, Jr
TAGS: antioxidants, attenuation, mitochondria, signal transduction, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3613-3624. doi: https://doi.org/10.1167/iovs.19-27542

ARVO Annual Meeting Abstract July 2019

Standardization and validation of intravitreal and systemic administration of aflibercept in preclinical models for angiogenesis

Simon Kaja; Symantas Ragauskas; Maria Vähätupa; Marc Cerrada-Gimenez; Satu Mering; Jenni J. Hakkarainen; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1629. doi:

ARVO Annual Meeting Abstract July 2019

Antioxidants protect against reactive astrocytosis-induced sensitization to oxidative stress

Anita K. Ghosh; Vidhya R Rao; Evan B Stubbs; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3791. doi:

ARVO Annual Meeting Abstract July 2019

Influence of serum from patients with Systemic Autoimmune Disease on IL-8 Expression in Human Corneal Epithelial Cells in Vitro.

Omer Iqbal; Avinash Kolli; Charles S Bouchard; Madeline Ripa; Adarsh Dharan; Simon Kaja; Edward Campbell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4739. doi:

ARVO Annual Meeting Abstract July 2019

Xanthohumol protects corneal epithelial cells against oxidative stress in vitro

Samatha Ankireddy; Harsh Nilesh Hariani; Karoline Anna Orloff; Avinash Kolli; Jenni J Hakkarainen; Anita K. Ghosh; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5743. doi:

ARVO Annual Meeting Abstract July 2018

Aflibercept shows strong dose-dependency when administered intravitreally in the mouse CNV model

Ruta Maciulaitiene; Symantas Ragauskas; Anna Mari Haapaniemi; Simon Kaja; Ingrida Januleviciene; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2631. doi:

ARVO Annual Meeting Abstract July 2018

Utility of approved dry-eye drugs as reference compounds in SiccaSystem TM - a standardized mouse desiccating stress model for dry-eye disease

Simon Kaja; Symantas Ragauskas; Agne Ziniauskaite; Anna Mari Haapaniemi; Jenni J. Hakkarainen; Henna Martiskainen; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2673. doi:

ARVO Annual Meeting Abstract July 2018

Neuroprotection of retinal ganglion cells via NMDA-dependent mechanism in the mouse non-arteritic anterior ischemic optic neuropathy (NAION) model

Symantas Ragauskas; Agne Ziniauskaite; Simon Kaja; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3204. doi:

ARVO Annual Meeting Abstract July 2018

Pre-clinical efficacy of OCU300 nanoemulsion for the treatment of ocular graft versus host disease (oGVHD).

Rasappa Arumugham; Gopalam Somasekhar; Arun K Upadhyay; Giedrius Kalesnykas; Simon Kaja; Sandeep Jain

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3287. doi:

ARVO Annual Meeting Abstract July 2018

Loxl1 knockdown precipitates phenotypes of reactive astrocytosis and elastinopathy in optic nerve head astrocytes

Sasha Rosen; Anita Ghosh; Evan B Stubbs; Vidhya R Rao; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3526. doi:

ARVO Annual Meeting Abstract July 2018

Combining ISTH0036, an antisense oligonucleotide targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA, with aflibercept as novel treatment strategy for neovascular retinal diseases

Michel Janicot; Giedrius Kalesnykas; Eugen Leo; Petra Fettes; Simon Kaja; Katja Wosikowski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):236. doi:

Cornea June 2018

Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome

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Agnė Žiniauskaitė; Symantas Ragauskas; Jenni J. Hakkarainen; Cadmus C. Rich; Rudolf Baumgartner; Giedrius Kalesnykas; David S. Albers; Simon Kaja
TAGS: cyclosporine, dry eye syndromes, eye, keratoconjunctivitis sicca, mice, pathology, syndrome, conjunctiva, goblet cells, cornea
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3088-3093. doi: https://doi.org/10.1167/iovs.18-24432

ARVO Annual Meeting Abstract June 2017

Targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA with ISTH0036 as Novel Therapeutic Intervention in Neovascular Ocular Disease

Katja Wosikowski; Inge van Hoven; Jooseppi Puranen; Lies de Groef; Anne Mari Haapaniemi; Jurgen Sergeys; Simon Kaja; Giedrius Kalesnykas; Lieve K M Moons; Michel Janicot

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1948. doi:

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Mechanical strain results causes cytoskeletal remodeling and cellular elastinopathy in primary optic nerve head astrocytes

Aspirin and its metabolite, hippuric acid, increase VEGF Expression in human retinal pigment epithelium cells

Subconjunctival Chemotherapeutic Delivery by Fibrin Sealant in the Treatment of Retinoblastoma

Xanthohumol protects corneal epithelial cells in experimental models for dry-eye disease

Automated quantification of CNV volume using deep learning AI algorithm

Comparative efficacy of bevacizumab and aflibercept in the rabbit DL-AAA model of chronic retinal neovascularization

Characterization of VEGF-induced retinal neovascularization in Dutch Belted rabbits using in vivo imaging.

Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells

Standardization and validation of intravitreal and systemic administration of aflibercept in preclinical models for angiogenesis

Antioxidants protect against reactive astrocytosis-induced sensitization to oxidative stress

Influence of serum from patients with Systemic Autoimmune Disease on IL-8 Expression in Human Corneal Epithelial Cells in Vitro.

Xanthohumol protects corneal epithelial cells against oxidative stress in vitro

Aflibercept shows strong dose-dependency when administered intravitreally in the mouse CNV model

Utility of approved dry-eye drugs as reference compounds in SiccaSystem TM - a standardized mouse desiccating stress model for dry-eye disease

Neuroprotection of retinal ganglion cells via NMDA-dependent mechanism in the mouse non-arteritic anterior ischemic optic neuropathy (NAION) model

Pre-clinical efficacy of OCU300 nanoemulsion for the treatment of ocular graft versus host disease (oGVHD).

Loxl1 knockdown precipitates phenotypes of reactive astrocytosis and elastinopathy in optic nerve head astrocytes

Combining ISTH0036, an antisense oligonucleotide targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA, with aflibercept as novel treatment strategy for neovascular retinal diseases

Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome

Targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA with ISTH0036 as Novel Therapeutic Intervention in Neovascular Ocular Disease

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