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Meeting Abstract (25)
Journal Articles (5)

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Investigative Ophthalmology & Visual Science (30)

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ARVO Annual Meeting Abstract (25)
Cornea (2)
Glaucoma (2)
Retina (1)

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Eye Anatomy and Disorders (4)
Glaucoma (2)
Biochemistry and Molecular Biology (1)
Cornea (1)
Genetics (1)
Immunology and Microbiology (1)
Retina (1)
Visual Neuroscience (1)

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mice (2)
acinar cells (1)
adult (1)
antibodies (1)
antioxidants (1)
apoptosis (1)
attenuation (1)
contrast sensitivity (1)
estrogen (1)
glaucoma (1)

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Glaucoma August 2019

Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells

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Vidhya R. Rao; Jonathan D. Lautz; Simon Kaja; Eileen M. Foecking; Emőke Lukács; Evan B. Stubbs, Jr
TAGS: antioxidants, attenuation, mitochondria, signal transduction, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3613-3624. doi: 10.1167/iovs.19-27542

ARVO Annual Meeting Abstract July 2019

Antioxidants protect against reactive astrocytosis-induced sensitization to oxidative stress

Anita K. Ghosh; Vidhya R Rao; Evan B Stubbs; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3791. doi:

ARVO Annual Meeting Abstract July 2019

Standardization and validation of intravitreal and systemic administration of aflibercept in preclinical models for angiogenesis

Simon Kaja; Symantas Ragauskas; Maria Vähätupa; Marc Cerrada-Gimenez; Satu Mering; Jenni J. Hakkarainen; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1629. doi:

ARVO Annual Meeting Abstract July 2019

Influence of serum from patients with Systemic Autoimmune Disease on IL-8 Expression in Human Corneal Epithelial Cells in Vitro.

Omer Iqbal; Avinash Kolli; Charles S Bouchard; Madeline Ripa; Adarsh Dharan; Simon Kaja; Edward Campbell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4739. doi:

ARVO Annual Meeting Abstract July 2019

Xanthohumol protects corneal epithelial cells against oxidative stress in vitro

Samatha Ankireddy; Harsh Nilesh Hariani; Karoline Anna Orloff; Avinash Kolli; Jenni J Hakkarainen; Anita K. Ghosh; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5743. doi:

ARVO Annual Meeting Abstract July 2018

Combining ISTH0036, an antisense oligonucleotide targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA, with aflibercept as novel treatment strategy for neovascular retinal diseases

Michel Janicot; Giedrius Kalesnykas; Eugen Leo; Petra Fettes; Simon Kaja; Katja Wosikowski

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):236. doi:

ARVO Annual Meeting Abstract July 2018

Aflibercept shows strong dose-dependency when administered intravitreally in the mouse CNV model

Ruta Maciulaitiene; Symantas Ragauskas; Anna Mari Haapaniemi; Simon Kaja; Ingrida Januleviciene; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2631. doi:

ARVO Annual Meeting Abstract July 2018

Utility of approved dry-eye drugs as reference compounds in SiccaSystem TM - a standardized mouse desiccating stress model for dry-eye disease

Simon Kaja; Symantas Ragauskas; Agne Ziniauskaite; Anna Mari Haapaniemi; Jenni J. Hakkarainen; Henna Martiskainen; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2673. doi:

ARVO Annual Meeting Abstract July 2018

Neuroprotection of retinal ganglion cells via NMDA-dependent mechanism in the mouse non-arteritic anterior ischemic optic neuropathy (NAION) model

Symantas Ragauskas; Agne Ziniauskaite; Simon Kaja; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3204. doi:

ARVO Annual Meeting Abstract July 2018

Pre-clinical efficacy of OCU300 nanoemulsion for the treatment of ocular graft versus host disease (oGVHD).

Rasappa Arumugham; Gopalam Somasekhar; Arun K Upadhyay; Giedrius Kalesnykas; Simon Kaja; Sandeep Jain

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3287. doi:

ARVO Annual Meeting Abstract July 2018

Loxl1 knockdown precipitates phenotypes of reactive astrocytosis and elastinopathy in optic nerve head astrocytes

Sasha Rosen; Anita Ghosh; Evan B Stubbs; Vidhya R Rao; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3526. doi:

Cornea June 2018

Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome

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Agnė Žiniauskaitė; Symantas Ragauskas; Jenni J. Hakkarainen; Cadmus C. Rich; Rudolf Baumgartner; Giedrius Kalesnykas; David S. Albers; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3088-3093. doi: 10.1167/iovs.18-24432

ARVO Annual Meeting Abstract June 2017

Targeting Transforming Growth Factor beta 2 (TGF-β2) mRNA with ISTH0036 as Novel Therapeutic Intervention in Neovascular Ocular Disease

Katja Wosikowski; Inge van Hoven; Jooseppi Puranen; Lies de Groef; Anne Mari Haapaniemi; Jurgen Sergeys; Simon Kaja; Giedrius Kalesnykas; Lieve K M Moons; Michel Janicot

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1948. doi:

ARVO Annual Meeting Abstract June 2017

Assessment of the effects of systemically administered levetiracetam in an ocular model for neuroprotection.

Ruta Maciulaitiene; Symantas Ragauskas; Giedre Pakuliene; Simon Kaja; Ingrida Januleviciene; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2571. doi:

ARVO Annual Meeting Abstract June 2017

Elevated hydrostatic pressure increases the sensitivity of optic nerve head astrocytes to an oxidative challenge

Vidhya R Rao; Alexandra D. Hegel; Jamie C. Floss; Jonathan Lautz; Vicki Husak; Evan B Stubbs; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4605. doi:

ARVO Annual Meeting Abstract September 2016

Restasis® prevents lacrimal gland pathology in the novel SiccaSystem TM standardized experimental platform for experimental dry-eye disease research

Agne Ziniauskaite; Symantas Ragauskas; Jooseppi Puranen; Anne Mari Haapaniemi; Giedrius Kalesnykas; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5690. doi:

ARVO Annual Meeting Abstract September 2016

Altered proteasome subunit expression correlates with vision loss in a preclinical glaucoma model.

Loreley Denise Robie; Micahla C Brown; Reid A Waldman; Stephanie L Grillo; Nilofer Qureshi; Simon Kaja; Peter Koulen

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6010. doi:

ARVO Annual Meeting Abstract September 2016

A topically delivered synthetic metalloporphyrin SOD mimetic improves hallmarks of dry-eye disease pathology.

Simon Kaja; Peter Koulen; Jooseppi Puranen; Symantas Ragauskas

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):396. doi:

ARVO Annual Meeting Abstract September 2016

Age-related differences in light sensitivity in BALB/c mice

Giedrius Kalesnykas; Symantas Ragauskas; Simon Kaja; Heikki Tanila; Henri Olavi Leinonen

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5004. doi:

ARVO Annual Meeting Abstract June 2015

Novel plate reader-based assay measuring glioprotection in primary adult optic nerve head astrocytes.

Simon Kaja; Andrew J Payne; Yuliya Naumchuk; Danish H. Zaidi; Saba Nawazish; Deborah Levy; Bryan C Gerdes; Peter Koulen

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):420. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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