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ARVO Annual Meeting Abstract June 2020

AAV capsid variants target canine and primate bipolar cells after subretinal and intravitreal delivery

William A Beltran; Natalia Dolgova; Valerie L Dufour; Iwabe Simone; Ryan F. Boyd; Joshua T Bartoe; Gustavo D Aguirre; David L schaffer; John Gerard Flannery; Leah Byrne

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4489.

ARVO Annual Meeting Abstract July 2019

Safety and long-term efficacy of AAV2- BEST1 gene augmentation therapy in canine model of Best vitelliform macular dystrophies

Karina E Guziewicz; Artur V Cideciyan; Brian T. Kendrick; Valerie L Dufour; Gordon Ruthel; Andras M Komaromy; Simone Iwabe; William Hauswirth; William A Beltran; Samuel G Jacobson; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5200.

ARVO Annual Meeting Abstract July 2018

BEST1 gene augmentation therapy corrects light-modulated retinal micro-detachments

Karina E Guziewicz; Artur V Cideciyan; William A Beltran; Andras M Komaromy; Valerie Dufour; Malgorzata Swider; Simone Iwabe; Alexander Sumaroka; Brian T Kendrick; Gordon Ruthel; Vince A Chiodo; Elise Heon; William W Hauswirth; Samuel G Jacobson; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4522.

ARVO Annual Meeting Abstract July 2018

AAV-mediated expression of X-linked Inhibitor of Apoptosis protects photoreceptors in two canine models of early onset RP

William A Beltran; Artur V Cideciyan; Simone Iwabe; Valerie Dufour; Jason Charng; Brianna Lisi; Jose-Manuel Guzman; Alireza Badiei; Catherine Tsilfidis; William W Hauswirth; Samuel G Jacobson; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4527.

ARVO Annual Meeting Abstract July 2018

Long-term preservation of photoreceptor function and structure following early-stage treatment by AAV-mediated gene augmentation in canine model of NPHP5 Leber congenital amaurosis

Gustavo D Aguirre; Artur V Cideciyan; Sanford L Boye; Simone Iwabe; Valerie Dufour; Malgorzata Swider; Karolina Roszak; William W Hauswirth; Samuel G Jacobson; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6006.

ARVO Annual Meeting Abstract June 2017

AAV-mediated Knockdown and Replacement of Rhodopsin Protects Rods in a Canine Model of RHO -ADRP

William A Beltran; Artur V Cideciyan; Raghavi Sudharsan; Michael Massengill; Brian Rossmiller; Valerie Liliane Dufour; felipe Pompeo Marinho; Tatyana Appelbaum; Malgorzata Swider; Mychajlo S. Kosyk; Simone Iwabe; William W Hauswirth; Samuel G Jacobson; Alfred S Lewin; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4483.

ARVO Annual Meeting Abstract June 2017

Quantitative and Qualitative Assessment of Retinal Degeneration in Canine Models of Inherited Retinal Diseases Using Spectral Domain Optical Coherence Tomography (SD-OCT)

Shin Ae Park; Jamie Rhodes; Simone Iwabe; Gui-Shuang Ying; J. Huang; Andras M Komaromy

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4869.

ARVO Annual Meeting Abstract June 2017

Variable cone dysfunction and progressive ophthalmoscopic changes in a canine model of RPGRIP1 and MAP9 multigenic cone-rod dystrophy

Keiko Miyadera; Felipe Pompeo Marinho; Kendra McDaid; Valerie Liliane Dufour; Simone Iwabe; Gautami Das; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):269.

ARVO Annual Meeting Abstract June 2017

Influence of Ambient Illumination on the Course of Retinal Degeneration in a Canine model of RHO-ADRP

Valerie Liliane Dufour; Simone Iwabe; Gustavo D Aguirre; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):278.

Visual Neuroscience January 2017

Assessment of Rod, Cone, and Intrinsically Photosensitive Retinal Ganglion Cell Contributions to the Canine Chromatic Pupillary Response

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Connie Y. Yeh; Kristin L. Koehl; Christine D. Harman; Simone Iwabe; José M. Guzman; Simon M. Petersen-Jones; Randy H. Kardon; András M. Komáromy
TAGS: dog, domestic, pupil reaction, retinal cone, rod photoreceptors, pupillometry, melanopsin, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):65-78. https://doi.org/10.1167/iovs.16-19865

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

RPGRIP1 mutant dogs show variable cone ERG functions

Gautami Das; Evelyn Santana; Simone Iwabe; Gustavo D Aguirre; Keiko Miyadera

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):167.

ARVO Annual Meeting Abstract September 2016

Two AAV2/5-mediated RPGR gene augmentation constructs driven by the GRK1 promoter rescue photoreceptor structure and function in a canine model o f RPGR X-linked retinitis pigmentosa

William A Beltran; Artur V Cideciyan; Simone Iwabe; Valerie Dufour; Felipe Pompeo Marinho; Guo-jie Ye; Mark Shearman; Jeffrey D Chulay; William Hauswirth; Samuel G Jacobson; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):785.

ARVO Annual Meeting Abstract September 2016

AAV-mediated gene augmentation restores retinal function and vision in the canine model of NPHP5 Leber congenital amaurosis

Gustavo D Aguirre; Artur V Cideciyan; Sanford L. Boye; Simone Iwabe; Valerie Dufour; Felipe Pompeo Marinho; Louise M Downs; William Hauswirth; Samuel G Jacobson; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract September 2016

Bestrophinopathy is an RPE-photoreceptor interface disease

Karina E Guziewicz; William A Beltran; Simone Iwabe; Artur V Cideciyan; Samuel G Jacobson; Anuradha Dhingra; Kathleen Battaglia; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract June 2015

Cone structure and function in dogs with RPGRIP1 mutation

Gautami Das; Evelyn Santana; Simone Iwabe; Gustavo D Aguirre; Keiko Miyadera

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4653.

ARVO Annual Meeting Abstract June 2015

Evaluation of the efficacy of mouse opsin promoter for rhodopsin gene augmentation in dogs

Raghavi Sudharsan; Simone Iwabe; Tatyana Appelbaum; Alfred S Lewin; William W Hauswirth; Gustavo D Aguirre; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5408.

ARVO Annual Meeting Abstract June 2015

GENETIC ABLATION OF 11-CIS RETINAL ACCELERATES RETINAL DEGENERATION IN THE CANINE T4R RHO MODEL OF ADRP BUT PREVENTS LIGHT-INDUCED DAMAGE

Simone Iwabe; Raghavi Sudharsan; Gustavo D Aguirre; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5418.

ARVO Annual Meeting Abstract June 2015

Photoreceptor development, degeneration and retinal gene expression in the canine NPHP5 Leber congenital amaurosis model

Gustavo D Aguirre; Louise M Downs; Sem Genini; Erin M. Scott; Simone Iwabe; William A Beltran

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5420.

ARVO Annual Meeting Abstract June 2015

Assessment of rod, cone, and intrinsically photosensitive retinal ganglion cell (ipRGC) contribution to the canine chromatic pupillary response

Connie Yeh; Kristin L Koehl; Christine Harman; Simone Iwabe; Jose Guzman; Simon M Petersen-Jones; Andras M Komaromy

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5569.

ARVO Annual Meeting Abstract June 2015

Gene therapy for RPGR -XLRP in a canine model results in retained photoreceptors and vision for at least 2.5 years

William A Beltran; Artur V Cideciyan; Simone Iwabe; Alfred S Lewin; Malgorzata Swider; Jose M Guzman; Sanford L Boye; William W Hauswirth; Samuel G Jacobson; Gustavo D Aguirre; RC

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2588.

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AAV capsid variants target canine and primate bipolar cells after subretinal and intravitreal delivery

Safety and long-term efficacy of AAV2- BEST1 gene augmentation therapy in canine model of Best vitelliform macular dystrophies

BEST1 gene augmentation therapy corrects light-modulated retinal micro-detachments

AAV-mediated expression of X-linked Inhibitor of Apoptosis protects photoreceptors in two canine models of early onset RP

Long-term preservation of photoreceptor function and structure following early-stage treatment by AAV-mediated gene augmentation in canine model of NPHP5 Leber congenital amaurosis

AAV-mediated Knockdown and Replacement of Rhodopsin Protects Rods in a Canine Model of RHO -ADRP

Quantitative and Qualitative Assessment of Retinal Degeneration in Canine Models of Inherited Retinal Diseases Using Spectral Domain Optical Coherence Tomography (SD-OCT)

Variable cone dysfunction and progressive ophthalmoscopic changes in a canine model of RPGRIP1 and MAP9 multigenic cone-rod dystrophy

Influence of Ambient Illumination on the Course of Retinal Degeneration in a Canine model of RHO-ADRP

Assessment of Rod, Cone, and Intrinsically Photosensitive Retinal Ganglion Cell Contributions to the Canine Chromatic Pupillary Response

RPGRIP1 mutant dogs show variable cone ERG functions

Two AAV2/5-mediated RPGR gene augmentation constructs driven by the GRK1 promoter rescue photoreceptor structure and function in a canine model o f RPGR X-linked retinitis pigmentosa

AAV-mediated gene augmentation restores retinal function and vision in the canine model of NPHP5 Leber congenital amaurosis

Bestrophinopathy is an RPE-photoreceptor interface disease

Cone structure and function in dogs with RPGRIP1 mutation

Evaluation of the efficacy of mouse opsin promoter for rhodopsin gene augmentation in dogs

GENETIC ABLATION OF 11-CIS RETINAL ACCELERATES RETINAL DEGENERATION IN THE CANINE T4R RHO MODEL OF ADRP BUT PREVENTS LIGHT-INDUCED DAMAGE

Photoreceptor development, degeneration and retinal gene expression in the canine NPHP5 Leber congenital amaurosis model

Assessment of rod, cone, and intrinsically photosensitive retinal ganglion cell (ipRGC) contribution to the canine chromatic pupillary response

Gene therapy for RPGR -XLRP in a canine model results in retained photoreceptors and vision for at least 2.5 years

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