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Meeting Abstract (14)
Journal Articles (2)

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Investigative Ophthalmology & Visual Science (16)

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ARVO Annual Meeting Abstract (14)
Cornea (2)

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Cornea (2)
Biochemistry and Molecular Biology (1)
Genetics (1)
Immunology and Microbiology (1)
Pharmacology (1)

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mice (2)
mice, inbred nod (2)
acinar cells (1)
adaptive testing (1)
cathepsins (1)
catheterization (1)
cats (1)
cytokine (1)
dacryoadenitis (1)
eyedrops (1)

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ARVO Annual Meeting Abstract June 2020

Intralacrimal Delivery of Rapa Shows Therapeutic Effects Without Systemic Toxicity in NOD Mice

Yaping Ju; Maria Edman; Hao Guo; Srikanth Reddy Janga; Santosh Peddi; J.Andrew MacKay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):144. doi:

ARVO Annual Meeting Abstract June 2020

Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren’s syndrome murine model

Runzhong Fu; Hao Guo; Srikanth Reddy Janga; Minchang Choi; Wannita Klinngam; Maria Edman; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1963. doi:

ARVO Annual Meeting Abstract July 2019

Development of a targeted carrier for Rapamycin in a murine model of Sjögren’s syndrome

Yaping Ju; Hao Guo; Frances Yarber; Maria Edman; Santosh Peddi; Srikanth Reddy Janga; John Andrew MacKay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2822. doi:

ARVO Annual Meeting Abstract July 2019

The α 1 -adrenergic agonist, phenylephrine, increases tear cathepsin S secretion through a Rab27a-independent pathway

Runzhong Fu; Srikanth Reddy Janga; Maria Edman; Frances Yarber; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4195. doi:

ARVO Annual Meeting Abstract July 2019

Tear biomarkers for Parkinson’s disease in basal versus reflex tears

Maria C Edman; Srikanth Reddy Janga; Daniel Freire; Danielle Feigenbaum; Wendy Mack; Curtis T Okamoto; Mark F Lew; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4196. doi:

ARVO Annual Meeting Abstract July 2018

Atrophy and Impaired Contraction of the Myoepithelial Cells in Lacrimal Glands of Sjögren’s Syndrome Animal Models of Dry Eye Disease

Driss Zoukhri; Dillon Hawley; Xin Tang; Tatiana Zyrianova; Mihir Shah; Srikanth Reddy Janga; Alexandra Letourneau; Martin Schicht; Friedrich P Paulsen; Sarah Hamm-Alvarez; Helen P Makarenkova

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2286. doi:

ARVO Annual Meeting Abstract July 2018

Cathepsin S Inhibitor Reduces Lacrimal Gland Inflammation and Increases Tear Flow In a Mouse Model of Sjögren’s Syndrome

Wannita Klinngam; Srikanth Reddy Janga; Maria C. Edman; Mihir Shah; Frances Yarber; Hao Guo; Benjamin Cooperman; Dandan Wang; Sarah Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2672. doi:

ARVO Annual Meeting Abstract July 2018

Comparison of NOD versus NOR Mice as Mouse Models of Autoimmune Dacryoadenitis

Yaping Ju; Srikanth Reddy Janga; Wannita Klinngam; Maria C. Edman; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3305. doi:

ARVO Annual Meeting Abstract July 2018

Tear Proteins as Possible Biomarkers for Parkinson’s Disease

Sarah F Hamm-Alvarez; Mark Lew; Danielle Feigenbaum; Srikanth Reddy Janga; Mihir Shah; Daniel Freire; Benjamin Cooperman; Raveena Ghanshani; Wendy Mack; Curtis Okamoto

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4909. doi:

ARVO Annual Meeting Abstract July 2018

Elastin-like polypeptide mediate subcutaneous delivery of Rapamycin in a murine model of Sjögren’s Syndrome

Changrim Lee; Hao Guo; Wannita Klinngam; Srikanth Reddy Janga; Frances Yarber; Maria C. Edman; Santosh Peddi; Sarah F Hamm-Alvarez; J. Andrew MacKay

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5677. doi:

Cornea January 2017

Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation In a Murine Model of Sjögren's Syndrome

PDF

Mihir Shah; Maria C. Edman; Srikanth Reddy Janga; Frances Yarber; Zhen Meng; Wannita Klinngam; Jonathan Bushman; Tao Ma; Siyu Liu; Stan Louie; Arjun Mehta; Chuanqing Ding; J. Andrew MacKay; Sarah F. Hamm-Alvarez
TAGS: eyedrops, inflammation, mice, rapamycin, dacryoadenitis, mice, inbred nod, sjogren's syndrome
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):372-385. doi: https://doi.org/10.1167/iovs.16-19159

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Topical Rapamycin suppresses lacrimal gland inflammation in a mouse model of Sjögren’s Syndrome

Mihir Shah; Srikanth Reddy Janga; Maria C Edman; Zhen Meng; Jingwen Chen; Tao Ma; Wannita Klingamm; Chuanqing Ding; John Andrew MacKay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4810. doi:

ARVO Annual Meeting Abstract June 2015

Four tear biomarkers distinguish Sjögren’s Syndrome patients from patients with other autoimmune diseases

Maria C Edman; Srikanth Reddy Janga; Alexander F Chen; Mercy Bechtold; Alice Kim; poysophon poysophon; Wendy J Mack; William Stohl; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2483. doi:

ARVO Annual Meeting Abstract June 2015

Longitudinal Characterization of Tear Fluid Cathepsin S, a Sjögren’s Syndrome Biomarker, in the male Non-Obese Diabetic mouse

Srikanth Reddy Janga; Maria C Edman; Tao Ma; Mihir Shah; Aida Kouhi; Jingwen Chen; Frances Yarber; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2484. doi:

ARVO Annual Meeting Abstract April 2014

Targeting of elastin-like polypeptide nanoparticles to ICAM-1 in lacrimal glands for therapy of SjÖgren's Syndrome

Pang Yu Hsueh; Srikanth Reddy Janga; John A Mackay; Sarah F Hamm-Alvarez

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4634. doi:

Cornea October 2010

Increased Expression of Cathepsins and Obesity-Induced Proinflammatory Cytokines in Lacrimal Glands of Male NOD Mouse

PDF

Xiaodong Li; Kaijin Wu; Maria Edman; Katja Schenke-Layland; Michelle MacVeigh-Aloni; Srikanth Reddy Janga; Barbara Schulz; Sarah F. Hamm-Alvarez
TAGS: adaptive testing, cathepsins, cats, cytokine, langer-giedion syndrome, lysate, mice, mice, inbred balb c, mice, inbred nod, obesity
Invest. Ophthalmol. Vis. Sci.. 2010; 51(10):5019-5029. doi: https://doi.org/10.1167/iovs.09-4523

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
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Translational Vision Science & Technology

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