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ARVO Annual Meeting Abstract June 2024

Stimulator of interferon genes (STING) as a therapeutic target for atrophic age-related macular degeneration

Pooja Gautam; Sayan Ghosh; Victoria Koontz; Sridhar Bammidi; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):759.

ARVO Annual Meeting Abstract June 2024

Monoclonal Antibody Development for Lipocalin-2 Neutralization in Atrophic AMD

Mihir Nemani; Emma Mahally; Sayan Ghosh; Victoria Koontz; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):752.

ARVO Annual Meeting Abstract June 2024

Role of IL-17A in driving inflammatory responses in progression of dry age-related macular degeneration

Sayan Ghosh; Victoria Koontz; Sridhar Bammidi; Pooja Gautam; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):737.

ARVO Annual Meeting Abstract June 2024

The influence of gut microbiome on inflammatory changes in the ocular environment is triggered by the peripheral immune system

Victoria Koontz; Sayan Ghosh; Sridhar Bammidi; Pooja Gautam; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1685.

ARVO Annual Meeting Abstract June 2024

Linking mitochondrial dysfunction to inflammation during the progression of atrophic age-related macular degeneration

Shruti Dhar; Victoria Koontz; Sridhar Bammidi; Mihir Nemani; Pooja Gautam; Stacey L Hose; Debasish Sinha; Sayan Ghosh

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2566.

ARVO Annual Meeting Abstract June 2024

Elevated mTORC1 and mTORC2 signaling in the retinal pigmented epithelium alters glucose metabolism, leading to a pathology resembling age-related macular degeneration

Sridhar Bammidi; Olivia Chowdhury; Sayan Ghosh; Victoria Koontz; Mihir Nemani; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2103.

ARVO Annual Meeting Abstract June 2023

Akt2 signaling in RPE contributes to retinal fibrosis in DR

Haitao Liu; Vishnu Maddipatla; Sayan Ghosh; Victoria Koontz; Stacey L Hose; J. Samuel Zigler Jr.; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):498.

ARVO Annual Meeting Abstract June 2023

SIRT5/Akt2 signaling axis regulates TFEB activity and autophagy in the RPE cells: Implications in dry age-related macular degeneration

Sayan Ghosh; Victoria Koontz; Mihir Nemani; Olivia Chowdhury; Haitao Liu; Stacey L Hose; J. Samuel Zigler Jr.; James T Handa; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5389.

ARVO Annual Meeting Abstract June 2022

The Role of the STING/Type I IFN Signaling Pathway in Diabetic Retinopathy

Haitao Liu; Anastasiia Strizhakova; Stacey L Hose; Chao Huang; Pamela Strassburger; Gabriella Widmer; Alan D Proia; Eleonora Lad; Peter Westenskow; Nikolaos Mitrousis; Derrick Feenstra; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):413.

ARVO Annual Meeting Abstract June 2022

The differential role of distinct astrocyte populations in Persistent Fetal Vasculature (PFV) disease

Victoria Koontz; Sayan Ghosh; Nadezda A Stepicheva; Haitao Liu; PENG SHANG; Olivia Chowdhury; Anastasiia Strizhakova; Rachel Daley; Stacey L Hose; J. Samuel Zigler; Meysam Yazdankhah; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):266 – F0311.

ARVO Annual Meeting Abstract June 2022

βA3/A1-crystallin may link lysosomal clearance and the circadian rhythm in the RPE

Anastasiia Strizhakova; Adithya Sreenivas; Victoria Koontz; Peng Shang; Haitao Liu; Sayan Ghosh; Olivia Chowdhury; Stacey L Hose; J. Samuel Zigler; Nadezda A Stepicheva; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):778 – F0337.

ARVO Annual Meeting Abstract June 2022

PITPβ/βA3/A1-crystallin complex is critical for PIP metabolism in retinal pigment epithelium (RPE)

Emma Rose Mahally; Rachel Daley; Kenneth Teel; Austin McCauley; Nadezda A Stepicheva; Sayan Ghosh; Haitao Liu; Olivia Chowdhury; Anastasiia Strizhakova; Victoria Koontz; Stacey L Hose; J. Samuel Zigler; Raju V S Rajala; Debasish Sinha; PENG SHANG

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2473 – F0180.

ARVO Annual Meeting Abstract June 2022

Looking for hidden cues: can the function of the moonlighting ocular protein βA3/A1-crystallin be regulated by the signals hidden in its coding sequence?

Nadezda A Stepicheva; Ekaterina Volkova; Victoria Koontz; PENG SHANG; Haitao Liu; Sayan Ghosh; Anastasiia Strizhakova; Olivia Chowdhury; Rachel Daley; J. Samuel Zigler; Stacey L Hose; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2300.

ARVO Annual Meeting Abstract June 2022

Inhibiting mTOR-independent TFEB activity in RPE alleviates the early AMD-like phenotype in a mouse model

Mihir Nemani; Haitao Liu; PENG SHANG; Olivia Chowdhury; Victoria Koontz; Nadezda A Stepicheva; Anastasiia Strizhakova; Rachel Daley; Stacey L Hose; J. Samuel Zigler; Debasish Sinha; Sayan Ghosh

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3038 – F0409.

ARVO Annual Meeting Abstract June 2022

Activation of mTOR signaling in the RPE cells induces alterations in melanogenesis thereby triggering oxidative stress

Olivia Chowdhury; Vishnu Maddipatla; Sayan Ghosh; Haitao Liu; PENG SHANG; Victoria Koontz; Nadezda A Stepicheva; Anastasiia Strizhakova; Rachel Daley; Stacey L Hose; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3033 – F0404.

ARVO Annual Meeting Abstract June 2022

Akt2 signaling in diabetes-induced dysfunction of the outer blood retina barrier

Rachel Daley; Sayan Ghosh; PENG SHANG; Nadezda A Stepicheva; Anastasiia Strizhakova; Olivia Chowdhury; Victoria Koontz; Stacey L Hose; J. Samuel Zigler; Debasish Sinha; Haitao Liu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3599 – A0054.

ARVO Annual Meeting Abstract June 2022

HDAC11 is a crucial regulator for visual cycle genes and retinal function

Peng Shang; Rachel Daley; Emma Rose Mahally; Nadezda A Stepicheva; Sayan Ghosh; Haitao Liu; Anastasiia Strizhakova; Olivia Chowdhury; Victoria Koontz; Stacey L Hose; J. Samuel Zigler; Jiang Qian; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4115 – F0352.

ARVO Annual Meeting Abstract June 2022

Crosstalk between metabolism and inflammation in dry age-related macular degeneration

Sayan Ghosh; PENG SHANG; Nadezda A Stepicheva; Haitao Liu; Olivia Chowdhury; Victoria Koontz; Anastasiia Strizhakova; Rachel Daley; Stacey L Hose; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4625 – F0417.

ARVO Annual Meeting Abstract June 2022

Lipocalin-2 homodimer variant: Role in dry age-related macular degeneration

Urvi Gupta; Sayan Ghosh; PENG SHANG; Haitao Liu; Anastasiia Strizhakova; Stacey L Hose; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4602 – F0394.

ARVO Annual Meeting Abstract June 2020

Mitochondrial abnormality in astrocytes leads to optic nerve degeneration: a mechanism mediated by CXCL14

Meysam Yazdankhah; Emily G. Boxi; Stacey L Hose; Nadezda A Stepicheva; Joseph Weiss; Sayan Ghosh; Peng Shang; Haitao Liu; Christopher Scott Fitting; Ming-Wen Hu; Jiang Qian; Peter Calabresi; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2791.

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Stimulator of interferon genes (STING) as a therapeutic target for atrophic age-related macular degeneration

Monoclonal Antibody Development for Lipocalin-2 Neutralization in Atrophic AMD

Role of IL-17A in driving inflammatory responses in progression of dry age-related macular degeneration

The influence of gut microbiome on inflammatory changes in the ocular environment is triggered by the peripheral immune system

Linking mitochondrial dysfunction to inflammation during the progression of atrophic age-related macular degeneration

Elevated mTORC1 and mTORC2 signaling in the retinal pigmented epithelium alters glucose metabolism, leading to a pathology resembling age-related macular degeneration

Akt2 signaling in RPE contributes to retinal fibrosis in DR

SIRT5/Akt2 signaling axis regulates TFEB activity and autophagy in the RPE cells: Implications in dry age-related macular degeneration

The Role of the STING/Type I IFN Signaling Pathway in Diabetic Retinopathy

The differential role of distinct astrocyte populations in Persistent Fetal Vasculature (PFV) disease

βA3/A1-crystallin may link lysosomal clearance and the circadian rhythm in the RPE

PITPβ/βA3/A1-crystallin complex is critical for PIP metabolism in retinal pigment epithelium (RPE)

Looking for hidden cues: can the function of the moonlighting ocular protein βA3/A1-crystallin be regulated by the signals hidden in its coding sequence?

Inhibiting mTOR-independent TFEB activity in RPE alleviates the early AMD-like phenotype in a mouse model

Activation of mTOR signaling in the RPE cells induces alterations in melanogenesis thereby triggering oxidative stress

Akt2 signaling in diabetes-induced dysfunction of the outer blood retina barrier

HDAC11 is a crucial regulator for visual cycle genes and retinal function

Crosstalk between metabolism and inflammation in dry age-related macular degeneration

Lipocalin-2 homodimer variant: Role in dry age-related macular degeneration

Mitochondrial abnormality in astrocytes leads to optic nerve degeneration: a mechanism mediated by CXCL14

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