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ARVO Annual Meeting Abstract June 2025

Visual Function and Quality of Life in Patients with Age-related Macular Degeneration and Early Atrophic Lesions

Robert Taylor Eakins; Yingjia Wei; Karen Daynes; Alicia Williams; Ray Nelson; Yue Zhang; Steffen Schmitz-Valckenberg; Monika Fleckenstein

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):687.

ARVO Annual Meeting Abstract June 2025

Structure-function correlation associated with type 1 macular neovascularization in AMD

Sandrine H. Künzel; Yingjia Wei; Irmak Karaca; Leon Alexander von der Emde; Ray Nelson; Karen Daynes; Alicia Williams; Frank G Holz; Yue Zhang; Steffen Schmitz-Valckenberg; Monika Fleckenstein

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):706.

ARVO Annual Meeting Abstract June 2025

Mesopic and Scotopic Patient-Tailored Fundus-Controlled Perimetry of Early Atrophic Lesions in Age-related Macular Degeneration

Sebastian Lee; Karen Daynes; Alicia Williams; Ray Nelson; Alex Quinton; Monika Fleckenstein; Steffen Schmitz-Valckenberg

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):716.

ARVO Annual Meeting Abstract June 2025

Mesopic and dark-adapted retinal sensitivity associated with type 1 macular neovascularization in AMD

Irmak Karaca; Yingjia Wei; Sandrine H. Künzel; Ray Nelson; Karen Daynes; Alicia Williams; Yue Zhang; Steffen Schmitz-Valckenberg; Monika Fleckenstein

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):668.

ARVO Annual Meeting Abstract June 2025

Machine learning in normative data prediction for mesopic and dark-adapted microperimetry

Yingjia Wei; Leon Alexander von der Emde; Irmak Karaca; Sandrine H. Künzel; Steffen Schmitz-Valckenberg; Monika Fleckenstein; Yue Zhang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4078.

ARVO Annual Meeting Abstract June 2025

Global real-world clinical and anatomical outcomes with faricimab in treatment-naïve patients with nAMD or DME from a prospective non-interventional study: The VOYAGER study

Robyn H Guymer; Steffen Schmitz-Valckenberg; Clare Bailey; Voraporn Chaikitmongkol; Varun Chaudhary; Gloria Chi; Amanda Downey; Robert P Finger; Adrian Hock Chaun Koh; Susumu Ishida; Monica Lövestam-Adrian; Mariacristina Parravano; José Domingo Luna; Veeral Sheth; Beijue Shi; Eric H. Souied; Diane Uschner

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3111.

ARVO Annual Meeting Abstract June 2025

Refining the Prognostic Value of Cuticular Drusen in Age-Related Macular Degeneration – a MACUSTAR Study Report

Jan Henrik Terheyden; Robert P Finger; Lourdes Vidal-Oliver; Sergio Leal; Klaus-Peter Moll; Steffen Schmitz-Valckenberg; David P Crabb; Ulrich F O Luhmann; Matthias Schmid; Frank G Holz; Charlotte Behning; Marlene Sassmannshausen

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4122.

ARVO Annual Meeting Abstract June 2025

Associations between disease progression, structural biomarkers and polygenic risk scores in intermediate age-related macular degeneration – a MACUSTAR report

Lukas Schlößer; Jan Henrik Terheyden; Charlotte Behning; Hannah Klinkhammer; Davide Garzone; Marlene Sassmannshausen; Sarah Thiele; Steffen Schmitz-Valckenberg; Carel C B Hoyng; Clara Sánchez; Matthias Schmid; Ulrich F O Luhmann; Nadia Zakaria; Sergio Leal; Frank G Holz; Robert Patrick Finger

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3674.

Artificial Intelligence September 2024

Generalizable Deep Learning for the Detection of Incomplete and Complete Retinal Pigment Epithelium and Outer Retinal Atrophy: A MACUSTAR Report

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Coen de Vente; Philippe Valmaggia; Carel B. Hoyng; Frank G. Holz; Mohammad M. Islam; Caroline C. W. Klaver; Camiel J. F. Boon; Steffen Schmitz-Valckenberg; Adnan Tufail; Marlene Saßmannshausen; Clara I. Sánchez; on behalf of the MACUSTAR Consortium
TAGS: datasets, deep learning, eye, retinal atrophy, retinal pigment epithelium, biological markers, cohort studies, training
Trans. Vis. Sci. Tech.. 2024; 13(9):11. https://doi.org/10.1167/tvst.13.9.11

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Comparison between OCT B-Scan and En Face Imaging for the Diagnosis of Early Macular Atrophy in Age-Related Macular Degeneration

Omer Trivizki; Yuxuan Cheng; Monika Fleckenstein; Steffen Schmitz-Valckenberg; Giovanni Gregori; Ruikang K Wang; Philip J Rosenfeld

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4829.

ARVO Annual Meeting Abstract June 2024

Geographic atrophy secondary to age-related macular degeneration: Significance of lesion location and functional determinants to vision-related quality of life

Eliza Eliza Broadbent; Sandrine H. Künzel; Philipp Möller; Moritz Linder; Lukas Goerdt; Joanna Czauderna; Steffen Schmitz-Valckenberg; Frank G Holz; Maximilian Pfau; Monika Fleckenstein

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5973.

ARVO Annual Meeting Abstract June 2024

Associations between structural phenotype and pathway-specific polygenic risk scores in intermediate age-related macular degeneration – a MACUSTAR report

Lukas Schloesser; Jan Henrik Terheyden; Charlotte Behning; Hannah Klinkhammer; Davide Garzone; Marlene Sassmannshausen; Steffen Schmitz-Valckenberg; Carel C B Hoyng; Clarisa Sanchez; Ulrich F O Luhmann; Klaus-Peter Moll; Sergio Leal; Matthias Schmid; Frank G Holz; Robert Finger

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):378.

ARVO Annual Meeting Abstract June 2024

Patient-tailored fundus-controlled perimetry testing in intermediate and early atrophic age-related macular degeneration

Steffen Schmitz-Valckenberg; Petrus Chang; Monika Fleckenstein; Frank G Holz; Zhichao Wu; Robyn H Guymer; Liang Liu; Hao Chen; Maximilian Pfau

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2794.

ARVO Annual Meeting Abstract June 2024

Clinical Manifestation of Macular Neovascularization in Age-related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5), on Chromosome 10 (ARMS2/HTRA1) or Both

Brian Solinsky; Steffen Schmitz-Valckenberg; Moussa A Zouache; Whitney Brinkley; Christian Pappas; Jill Hageman; Monika Fleckenstein; Gregory S Hageman

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2788.

ARVO Annual Meeting Abstract June 2024

Association of Ellipsoid Zone Reflectivity and Choriocapillaris Flow in Age-Related Macular Degeneration: a MACUSTAR study report

Yannick N. Liermann; Ben Isselmann; Marlene Sassmannshausen; Sandrine H. Künzel; Ulrich F O Luhmann; Sergio Leal; Matthias Schmid; Robert Finger; Steffen Schmitz-Valckenberg; Frank G Holz; Charlotte Behning; Sarah Thiele

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2315.

ARVO Annual Meeting Abstract June 2024

Remofuscin slows retinal thinning in Stargardt Disease (STGD1) – results from the Stargardt Remofuscin Treatment Trial (STARTT) a 2-year placebo-controlled study.

Tobias Peters; Katarina Stingl; Wolfgang Klein; Mario G Fsadni; Nils Meland; Patty P.A. Dhooge; Camiel Boon; Andrew Lotery; Maurizio Battaglia Parodi; Philipp Herrmann; Frank G Holz; Steffen Schmitz-Valckenberg; Philipp Möller; Carel C B Hoyng

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2205.

ARVO Annual Meeting Abstract June 2024

Validating a Confirmatory Structure-Function Model Prognostic of Progression of Intermediate AMD: MACUSTAR Study Primary Endpoint Analysis

Charlotte Behning; Jan Henrik Terheyden; Robert Finger; Hannah M P Dunbar; Marlene Sassmannshausen; Adnan Tufail; David P. Crabb; Alison M Binns; Zhichao Wu; Robyn H Guymer; Nadia Zakaria; Sergio Leal; Steffen Schmitz-Valckenberg; Ulrich F O Luhmann; Matthias Schmid; Frank G Holz

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4314.

ARVO Annual Meeting Abstract June 2024

Prognostic value of structural biomarkers for disease progression in intermediate age-related macular degeneration: a MACUSTAR study report

Marlene Sassmannshausen; Sarah Thiele; Jan Henrik Terheyden; Ulrich F O Luhmann; Sergio Leal; Matthias Schmid; Robert Finger; Frank G Holz; Steffen Schmitz-Valckenberg; Charlotte Behning

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5684.

Retina April 2024

Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years

PDF

Marlene Saßmannshausen; Senem Döngelci; Marc Vaisband; Leon von der Emde; Kenneth R. Sloan; Jan Hasenauer; Frank G. Holz; Steffen Schmitz-Valckenberg; Thomas Ach
TAGS: age-related macular degeneration, biological markers
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):45. https://doi.org/10.1167/iovs.65.4.45

Includes: Supplemental Content

Retina July 2023

Geographic Atrophy Segmentation Using Multimodal Deep Learning

PDF

Theodore Spaide; Jiaxiang Jiang; Jasmine Patil; Neha Anegondi; Verena Steffen; Michael G. Kawczynski; Elizabeth M. Newton; Christina Rabe; Simon S. Gao; Aaron Y. Lee; Frank G. Holz; SriniVas Sadda; Steffen Schmitz-Valckenberg; Daniela Ferrara
TAGS: atrophy, datasets, deep learning, screening, training, diagnostic imaging
Trans. Vis. Sci. Tech.. 2023; 12(7):10. https://doi.org/10.1167/tvst.12.7.10

Includes: Supplemental Content

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Visual Function and Quality of Life in Patients with Age-related Macular Degeneration and Early Atrophic Lesions

Structure-function correlation associated with type 1 macular neovascularization in AMD

Mesopic and Scotopic Patient-Tailored Fundus-Controlled Perimetry of Early Atrophic Lesions in Age-related Macular Degeneration

Mesopic and dark-adapted retinal sensitivity associated with type 1 macular neovascularization in AMD

Machine learning in normative data prediction for mesopic and dark-adapted microperimetry

Global real-world clinical and anatomical outcomes with faricimab in treatment-naïve patients with nAMD or DME from a prospective non-interventional study: The VOYAGER study

Refining the Prognostic Value of Cuticular Drusen in Age-Related Macular Degeneration – a MACUSTAR Study Report

Associations between disease progression, structural biomarkers and polygenic risk scores in intermediate age-related macular degeneration – a MACUSTAR report

Generalizable Deep Learning for the Detection of Incomplete and Complete Retinal Pigment Epithelium and Outer Retinal Atrophy: A MACUSTAR Report

Comparison between OCT B-Scan and En Face Imaging for the Diagnosis of Early Macular Atrophy in Age-Related Macular Degeneration

Geographic atrophy secondary to age-related macular degeneration: Significance of lesion location and functional determinants to vision-related quality of life

Associations between structural phenotype and pathway-specific polygenic risk scores in intermediate age-related macular degeneration – a MACUSTAR report

Patient-tailored fundus-controlled perimetry testing in intermediate and early atrophic age-related macular degeneration

Clinical Manifestation of Macular Neovascularization in Age-related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5), on Chromosome 10 (ARMS2/HTRA1) or Both

Association of Ellipsoid Zone Reflectivity and Choriocapillaris Flow in Age-Related Macular Degeneration: a MACUSTAR study report

Remofuscin slows retinal thinning in Stargardt Disease (STGD1) – results from the Stargardt Remofuscin Treatment Trial (STARTT) a 2-year placebo-controlled study.

Validating a Confirmatory Structure-Function Model Prognostic of Progression of Intermediate AMD: MACUSTAR Study Primary Endpoint Analysis

Prognostic value of structural biomarkers for disease progression in intermediate age-related macular degeneration: a MACUSTAR study report

Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years

Geographic Atrophy Segmentation Using Multimodal Deep Learning

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