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Perspective February 2020

Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations

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Ian M. MacDonald; Christopher Moen; Jacque L. Duncan; Stephen H. Tsang; Jasmina Cehajic-Kapetanovic; Tomas S. Aleman
TAGS: choroideremia, gene therapy, retinal degeneration, spatial vectors
Trans. Vis. Sci. Tech.. 2020; 9(3):17. doi: https://doi.org/10.1167/tvst.9.3.17

Retina September 2019

Patterns and Intensities of Near-Infrared and Short-Wavelength Fundus Autofluorescence in Choroideremia Probands and Carriers

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Maarjaliis Paavo; Jose R. L. Carvalho, Jr; Winston Lee; Jesse D. Sengillo; Stephen H. Tsang; Janet R. Sparrow
TAGS: choroideremia, eye, fundus autofluorescence imaging, multimodal imaging, proband, spectral-domain optical coherence tomography, diagnostic imaging, visual acuity, choroid, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):3752-3761. doi: https://doi.org/10.1167/iovs.19-27366

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

LACK OF VERTICAL STABILITY RESULTS IN EPITELIal-MESENCHYMAL TRANSITION OF THE IPS-DERIVED RETINAL PIGMENT EPITHELIAL CELL

Qun Zeng; Yao Li; Eyup Karahan; Stephen H Tsang; Tongalp H Tezel

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3935. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Multimodal structural disease progression of retinitis pigmentosa according to mode of inheritance

Ruben Jauregui; Vitor K. L. Takahashi; Karen Sophia Park; Julia Takiuti; Stephen H Tsang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4528. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Choriocapillaris atrophy in ABCA4 retinopathy is secondary to retinal pigment epithelium impairment

Karen Sophia Park; Ruben Jauregui; Janet Sparrow; Rando Allikmets; Stephen H. Tsang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4569. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Mice with RPE-specific CLIC4 deficiency exhibit AMD-like changes in the retina-RPE-choroid complex

Wataru Otsu; Kuo-Shun Hsu; Joshua L Dunaief; Yao Li; Stephen H. Tsang; Jen-Zen Chuang; Ching-Hwa Sung

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1229. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

THE USE OF ARTIFICIAL INTELLIGENCE FOR THE DETECTION OF STARGARDT’S DISEASE FROM FUNDUS IMAGES

Saad Y Al-Kadhi; Loai Skouti; April Ellis; Qun Zeng; Tarun Sharma; Stephen H Tsang; Tongalp H Tezel

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1501. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Multimodal imaging and electroretinography analysis of end-stage presentations of X-linked retinoschisis

Jesse D Sengillo; Winston Lee; Ruben Jauregui; Stephen H Tsang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5422. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Anatomical and fixation parameters as predictors of reading speed (RS) in Stargardt Disease

Gabrielle DeBartolomeo; Justin Tyler Zaremba; Zach Strecker; Christine Nichols Kay; Stephen H Tsang; Thomas B. Connor; Michael B Gorin; Paul S Bernstein; Byron L Lam; Ilyas Washington; Hendrik P Scholl; Leonide Saad

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1063. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

The Visual Function Index (VF-14) reflects a notable loss in Vision-Related Quality of Life (VRQOL) in Stargardt Disease

Justin Tyler Zaremba; Zach Strecker; Gabrielle DeBartolomeo; Stephen H Tsang; Christine Nichols Kay; Thomas B. Connor; Michael B Gorin; Paul S Bernstein; Byron L Lam; Ilyas Washington; Hendrik P Scholl; Leonide Saad

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4970. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials

Katherine Wert; Susanne F. Koch; Gabriel Velez; Chun-Wei Hsu; MaryAnn Mahajan; Alexander G. Bassuk; Stephen H. Tsang; Vinit B Mahajan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):396. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Stargardt disease ALK-001 phase 2 clinical trial: 12-month interim data

Hendrik P Scholl; Stephen H Tsang; Christine Nichols Kay; Thomas B. Connor; Michael B Gorin; Paul S Bernstein; Byron L Lam; Zach Strecker; Justin Tyler Zaremba; Gabrielle DeBartolomeo; Ilyas Washington; Leonide Saad

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1336. doi: https://doi.org/

Retina June 2019

Characterization of Retinal Structure in ATF6 -Associated Achromatopsia

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Rebecca R. Mastey; Michalis Georgiou; Christopher S. Langlo; Angelos Kalitzeos; Emily J. Patterson; Thomas Kane; Navjit Singh; Ajoy Vincent; Anthony T. Moore; Stephen H. Tsang; Jonathan H. Lin; Marielle P. Young; M. Elizabeth Hartnett; Elise Héon; Susanne Kohl; Michel Michaelides; Joseph Carroll
TAGS: achromatopsia, diagnostic imaging, mosaicism, retina, retinal cone, rod photoreceptors, parafoveal region, photoreceptors, genetics, fovea centralis
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2631-2640. doi: https://doi.org/10.1167/iovs.19-27047

Retina May 2019

Multimodal Imaging in Best Vitelliform Macular Dystrophy

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Jose Ronaldo Lima de Carvalho, Jr; Maarjaliis Paavo; Lijuan Chen; John Chiang; Stephen H. Tsang; Janet R. Sparrow
TAGS: eye, vitelliform dystrophy, autofluorescence, spectral-domain optical coherence tomography, multimodal imaging
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2012-2022. doi: https://doi.org/10.1167/iovs.19-26571

Retina January 2019

VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site

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Peter H. Tang; Gabriel Velez; Stephen H. Tsang; Alexander G. Bassuk; Vinit B. Mahajan
TAGS: mutation, exons, gelatinase a, surgical procedures, operative, vitreous body, eye, retina, cytokinesis, tissue degeneration, histopathology tests
Invest. Ophthalmol. Vis. Sci.. 2019; 60(1):282-293. doi: https://doi.org/10.1167/iovs.18-25624

Includes: Supplemental Content

Review September 2018

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

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Gabriel Velez; Peter H. Tang; Thiago Cabral; Galaxy Y. Cho; Daniel A. Machlab; Stephen H. Tsang; Alexander G. Bassuk; Vinit B. Mahajan
TAGS: biological markers, health, body tissue, vitreous body, eye, proteins, proteomics, vitreoretinal disease, precision
Trans. Vis. Sci. Tech.. 2018; 7(5):12. doi: https://doi.org/10.1167/tvst.7.5.12

ARVO Annual Meeting Abstract July 2018

Quantitative comparison of near-infrared versus short-wave autofluorescence imaging in monitoring progression of retinitis pigmentosa

Ruben Jauregui; xuan cui; Jimmy Duong; Stephen H Tsang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):51. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Systemic PDE 5/6 treatment of macular disease and dystrophy – long term vision and OCT results

D Jackson Coleman; Winston Lee; Stanley Chang; Suzanne Daly; Harriet O Lloyd; Stephen H Tsang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):69. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Regions of Disease Sparing Spatially Correlate with Choroidal Thinning in ABCA4 Disease

Winston Lee; Maarjaliis Paavo; Jana Zernant; Stephen H. Tsang; Janet R Sparrow; Rando Allikmets

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):787. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

The Natural History of the Progression of Choroideremia (NIGHT) Study: Longitudinal Changes in Visual Acuity over 12 Months

Mark E Pennesi; Byron L Lam; M Dominik Fischer; Eeva-Marja Kaarina Sankila; Frank G. Holz; Robert E MacLaren; David G Birch; Ian M MacDonald; Graeme Black; Carel C B Hoyng; Neil M Bressler; Stephen H. Tsang; Kimberly E Stepien; Michael S Ip; Vedran Pavlovic; Aniz Girach

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3898. doi: https://doi.org/

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Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations

Patterns and Intensities of Near-Infrared and Short-Wavelength Fundus Autofluorescence in Choroideremia Probands and Carriers

LACK OF VERTICAL STABILITY RESULTS IN EPITELIal-MESENCHYMAL TRANSITION OF THE IPS-DERIVED RETINAL PIGMENT EPITHELIAL CELL

Multimodal structural disease progression of retinitis pigmentosa according to mode of inheritance

Choriocapillaris atrophy in ABCA4 retinopathy is secondary to retinal pigment epithelium impairment

Mice with RPE-specific CLIC4 deficiency exhibit AMD-like changes in the retina-RPE-choroid complex

THE USE OF ARTIFICIAL INTELLIGENCE FOR THE DETECTION OF STARGARDT’S DISEASE FROM FUNDUS IMAGES

Multimodal imaging and electroretinography analysis of end-stage presentations of X-linked retinoschisis

Anatomical and fixation parameters as predictors of reading speed (RS) in Stargardt Disease

The Visual Function Index (VF-14) reflects a notable loss in Vision-Related Quality of Life (VRQOL) in Stargardt Disease

CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials

Stargardt disease ALK-001 phase 2 clinical trial: 12-month interim data

Characterization of Retinal Structure in ATF6 -Associated Achromatopsia

Multimodal Imaging in Best Vitelliform Macular Dystrophy

VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site

Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease

Quantitative comparison of near-infrared versus short-wave autofluorescence imaging in monitoring progression of retinitis pigmentosa

Systemic PDE 5/6 treatment of macular disease and dystrophy – long term vision and OCT results

Regions of Disease Sparing Spatially Correlate with Choroidal Thinning in ABCA4 Disease

The Natural History of the Progression of Choroideremia (NIGHT) Study: Longitudinal Changes in Visual Acuity over 12 Months

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