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Meeting Abstract (14)
Journal Articles (4)

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Investigative Ophthalmology & Visual Science (18)

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ARVO Annual Meeting Abstract (14)
Lens (3)
Retina (1)

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Eye Anatomy and Disorders (4)
Lens (3)
Genetics (1)
Immunology and Microbiology (1)
Retina (1)

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lens (device) (3)
lens, crystalline (3)
gap junction protein (2)
personal integrity (2)
child (1)
connexin 43 (1)
electroretinography (1)
family (1)
lens cell (1)
mice (1)

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ARVO Annual Meeting Abstract June 2022

Mechano-activated Connexin Hemichannels and Glutathione Transport Protect Lens Fiber Cells against Oxidative Insults

Jean Jiang; Yuxin Tong; Manuel Riquelme; Yu Du; Yumeng Quan; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3106. doi:

ARVO Annual Meeting Abstract June 2020

Connexin 43 Hemichannels Protect Lens Epithelial Cells Against Oxidative Damage through Regulation of Intracellular GSH and ROS levels

Yumeng Quan; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1017. doi:

ARVO Annual Meeting Abstract June 2020

The second Extracellular Domain of Connexin 50 Mediates Lens Development by Mediating cell-cell Adhesion

Jean X Jiang; Zhen Li; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2303. doi:

ARVO Annual Meeting Abstract June 2020

Embryonic Chick Lens Serves as an in vivo Model for Studying Congenital Cataract Mutations

Zhen Li; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2854. doi:

ARVO Annual Meeting Abstract June 2020

Macrophages Play a Key Role in Repairing Lens Posterior Capsule Rapture, Fiber Protrusion and Promotion of Fibrosis

Yuting Li; Sumin Gu; Hongyun Cheng; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5024. doi:

Lens September 2019

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers

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Sumin Gu; Sondip Biswas; Luis Rodriguez; Zhen Li; Yuting Li; Manuel A. Riquelme; Wen Shi; Ke Wang; Thomas W. White; Matthew Reilly; Woo-Kuen Lo; Jean X. Jiang
TAGS: lens (device), lens, crystalline, gap junction protein, mice, personal integrity
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4021-4032. doi: https://doi.org/10.1167/iovs.18-26270

ARVO Annual Meeting Abstract July 2019

Mechanical-sensitive hemichannels regulated by integrins mediates the delivery of glucose and glutathione into lens fiber cells

Jie Liu; Manuel Riquelme; Zhen Li; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4794. doi:

ARVO Annual Meeting Abstract June 2017

Connexin Hemichannels Protect Lens Fiber Cells Against Oxidative Stress

Jean X Jiang; wen shi; Manuel Riquelme; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2475. doi:

ARVO Annual Meeting Abstract September 2016

Lens Connexin Hemichannels are Responsive to Mechanical Stimulation and Oxidative Stress, and Protect Cell against Oxidative Stress

Wen Shi; Manuel A Riquelme; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Cell-Cell Adhesion Mediated by the Second Extracellular Domain of Connexin 50 Promotes Lens Epithelial-Fiber Cell Differentiation

Jean X Jiang; Zhengping Hu; Wen Shi; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3070. doi:

ARVO Annual Meeting Abstract June 2015

Connexin 46 G143R Mutation in Intracellular Loop Domain Alters its Interaction with C-terminal domain and Calmodulin, and Gating of Hemichannels

Jean X Jiang; Zhengping Hu; Bin Wang; Robert Brenner; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4658. doi:

ARVO Annual Meeting Abstract June 2015

Connexin 50 Functions as an Adhesive Molecule and Promotes the Cell-Cell Adhesion Function of Aquaporin 0 in the Lens

zhengping Hu; Sumin Gu; Sondip K Biswas; Alan Shiels; Thomas William White; Woo-Kuen Lo; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2644. doi:

ARVO Annual Meeting Abstract April 2014

Aquaporin-0 Targets Interlocking Protrusions to Control Integrity and Transparency of the Mouse Lens

Woo-Kuen Lo; Sondip K Biswas; Lawrence Brako; Alan Shiels; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1684. doi:

Lens March 2014

Aquaporin-0 Targets Interlocking Domains to Control the Integrity and Transparency of the Eye Lens

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Woo-Kuen Lo; Sondip K. Biswas; Lawrence Brako; Alan Shiels; Sumin Gu; Jean X. Jiang
TAGS: lens (device), lens, crystalline, personal integrity, transparency, water channels, proteins
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1202-1212. doi: https://doi.org/10.1167/iovs.13-13379

ARVO Annual Meeting Abstract April 2011

In vivo Phosphorylation of Lens Connexin 50 by Protein Kinase A Enhances Gap Junction and Hemichannel Function

Jean X. Jiang; Jialu Liu; Jose F. Ek Vitorin; Janis M. Burt; Sumin Gu; Qian Shi

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3929. doi:

ARVO Annual Meeting Abstract April 2011

Localized Alterations of Aquaporin Junctions and Connexin 50 Coincide with Cortical Cataract Formation in the Emory Mutant Mice

Woo-Kuen Lo; Sondip K. Biswas; Sumin Gu; Jean X. Jiang

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3410. doi:

Lens May 2003

Stimulation of Lens Cell Differentiation by Gap Junction Protein Connexin 45.6

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Sumin Gu; X. Sean Yu; Xinye Yin; Jean X. Jiang
TAGS: gap junction protein, lens (device), lens cell, lens, crystalline, retroviridae, connexin 43
Invest. Ophthalmol. Vis. Sci.. 2003; 44(5):2103-2111. doi: https://doi.org/10.1167/iovs.02-1045

Retina August 2000

Early-Onset Severe Rod–Cone Dystrophy in Young Children with RPE65 Mutations

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Birgit Lorenz; Peter Gyürüs; Markus Preising; Dirk Bremser; Sumin Gu; Monika Andrassi; Christina Gerth; Andreas Gal
TAGS: child, family, mutation, retinitis pigmentosa, electroretinography
Invest. Ophthalmol. Vis. Sci.. 2000; 41(9):2735-2742. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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