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ARVO Annual Meeting Abstract June 2023

Connexin 50 Inhibits Lens Epithelial Cells Migration and Epithelial-Mesenchymal Transition

Bo Ma; Zhen Li; Guangyan Wang; Sumin Gu; Jean X. Jiang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5119.

ARVO Annual Meeting Abstract June 2023

Functional Interplay of Connexin Hemichannels in Glutathione Export from Lens Epithelial Cells and in Fiber Cell protection against Oxidative Stress

Guangyan Wang; Yumeng Quan; Bo Ma; Sumin Gu; Jean X. Jiang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5118.

ARVO Annual Meeting Abstract June 2023

Inhibition of connexin hemichannels in astrocytes protects retinal ganglion cells and axons against optical never injuries

Jianping Zhang; Yu Du; Sumin Gu; Jean X. Jiang

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2582.

ARVO Annual Meeting Abstract June 2022

Mechano-activated Connexin Hemichannels and Glutathione Transport Protect Lens Fiber Cells against Oxidative Insults

Jean Jiang; Yuxin Tong; Manuel Riquelme; Yu Du; Yumeng Quan; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3106.

ARVO Annual Meeting Abstract June 2020

Connexin 43 Hemichannels Protect Lens Epithelial Cells Against Oxidative Damage through Regulation of Intracellular GSH and ROS levels

Yumeng Quan; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1017.

ARVO Annual Meeting Abstract June 2020

The second Extracellular Domain of Connexin 50 Mediates Lens Development by Mediating cell-cell Adhesion

Jean X Jiang; Zhen Li; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2303.

ARVO Annual Meeting Abstract June 2020

Embryonic Chick Lens Serves as an in vivo Model for Studying Congenital Cataract Mutations

Zhen Li; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2854.

ARVO Annual Meeting Abstract June 2020

Macrophages Play a Key Role in Repairing Lens Posterior Capsule Rapture, Fiber Protrusion and Promotion of Fibrosis

Yuting Li; Sumin Gu; Hongyun Cheng; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5024.

Lens September 2019

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers

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Sumin Gu; Sondip Biswas; Luis Rodriguez; Zhen Li; Yuting Li; Manuel A. Riquelme; Wen Shi; Ke Wang; Thomas W. White; Matthew Reilly; Woo-Kuen Lo; Jean X. Jiang
TAGS: lens (device), lens, crystalline, gap junction protein, mice, personal integrity
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4021-4032. https://doi.org/10.1167/iovs.18-26270

ARVO Annual Meeting Abstract July 2019

Mechanical-sensitive hemichannels regulated by integrins mediates the delivery of glucose and glutathione into lens fiber cells

Jie Liu; Manuel Riquelme; Zhen Li; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4794.

ARVO Annual Meeting Abstract June 2017

Connexin Hemichannels Protect Lens Fiber Cells Against Oxidative Stress

Jean X Jiang; wen shi; Manuel Riquelme; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2475.

ARVO Annual Meeting Abstract September 2016

Cell-Cell Adhesion Mediated by the Second Extracellular Domain of Connexin 50 Promotes Lens Epithelial-Fiber Cell Differentiation

Jean X Jiang; Zhengping Hu; Wen Shi; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3070.

ARVO Annual Meeting Abstract September 2016

Lens Connexin Hemichannels are Responsive to Mechanical Stimulation and Oxidative Stress, and Protect Cell against Oxidative Stress

Wen Shi; Manuel A Riquelme; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

ARVO Annual Meeting Abstract June 2015

Connexin 46 G143R Mutation in Intracellular Loop Domain Alters its Interaction with C-terminal domain and Calmodulin, and Gating of Hemichannels

Jean X Jiang; Zhengping Hu; Bin Wang; Robert Brenner; Sumin Gu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4658.

ARVO Annual Meeting Abstract June 2015

Connexin 50 Functions as an Adhesive Molecule and Promotes the Cell-Cell Adhesion Function of Aquaporin 0 in the Lens

zhengping Hu; Sumin Gu; Sondip K Biswas; Alan Shiels; Thomas William White; Woo-Kuen Lo; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2644.

ARVO Annual Meeting Abstract April 2014

Aquaporin-0 Targets Interlocking Protrusions to Control Integrity and Transparency of the Mouse Lens

Woo-Kuen Lo; Sondip K Biswas; Lawrence Brako; Alan Shiels; Sumin Gu; Jean X Jiang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1684.

Lens March 2014

Aquaporin-0 Targets Interlocking Domains to Control the Integrity and Transparency of the Eye Lens

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Woo-Kuen Lo; Sondip K. Biswas; Lawrence Brako; Alan Shiels; Sumin Gu; Jean X. Jiang
TAGS: lens (device), lens, crystalline, personal integrity, transparency, water channels, proteins
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1202-1212. https://doi.org/10.1167/iovs.13-13379

ARVO Annual Meeting Abstract April 2011

Localized Alterations of Aquaporin Junctions and Connexin 50 Coincide with Cortical Cataract Formation in the Emory Mutant Mice

Woo-Kuen Lo; Sondip K. Biswas; Sumin Gu; Jean X. Jiang

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3410.

ARVO Annual Meeting Abstract April 2011

In vivo Phosphorylation of Lens Connexin 50 by Protein Kinase A Enhances Gap Junction and Hemichannel Function

Jean X. Jiang; Jialu Liu; Jose F. Ek Vitorin; Janis M. Burt; Sumin Gu; Qian Shi

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3929.

Lens May 2003

Stimulation of Lens Cell Differentiation by Gap Junction Protein Connexin 45.6

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Sumin Gu; X. Sean Yu; Xinye Yin; Jean X. Jiang
TAGS: gap junction protein, lens (device), lens cell, lens, crystalline, retroviridae, connexin 43
Invest. Ophthalmol. Vis. Sci.. 2003; 44(5):2103-2111. https://doi.org/10.1167/iovs.02-1045

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Connexin 50 Inhibits Lens Epithelial Cells Migration and Epithelial-Mesenchymal Transition

Functional Interplay of Connexin Hemichannels in Glutathione Export from Lens Epithelial Cells and in Fiber Cell protection against Oxidative Stress

Inhibition of connexin hemichannels in astrocytes protects retinal ganglion cells and axons against optical never injuries

Mechano-activated Connexin Hemichannels and Glutathione Transport Protect Lens Fiber Cells against Oxidative Insults

Connexin 43 Hemichannels Protect Lens Epithelial Cells Against Oxidative Damage through Regulation of Intracellular GSH and ROS levels

The second Extracellular Domain of Connexin 50 Mediates Lens Development by Mediating cell-cell Adhesion

Embryonic Chick Lens Serves as an in vivo Model for Studying Congenital Cataract Mutations

Macrophages Play a Key Role in Repairing Lens Posterior Capsule Rapture, Fiber Protrusion and Promotion of Fibrosis

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers

Mechanical-sensitive hemichannels regulated by integrins mediates the delivery of glucose and glutathione into lens fiber cells

Connexin Hemichannels Protect Lens Fiber Cells Against Oxidative Stress

Cell-Cell Adhesion Mediated by the Second Extracellular Domain of Connexin 50 Promotes Lens Epithelial-Fiber Cell Differentiation

Lens Connexin Hemichannels are Responsive to Mechanical Stimulation and Oxidative Stress, and Protect Cell against Oxidative Stress

Connexin 46 G143R Mutation in Intracellular Loop Domain Alters its Interaction with C-terminal domain and Calmodulin, and Gating of Hemichannels

Connexin 50 Functions as an Adhesive Molecule and Promotes the Cell-Cell Adhesion Function of Aquaporin 0 in the Lens

Aquaporin-0 Targets Interlocking Protrusions to Control Integrity and Transparency of the Mouse Lens

Aquaporin-0 Targets Interlocking Domains to Control the Integrity and Transparency of the Eye Lens

Localized Alterations of Aquaporin Junctions and Connexin 50 Coincide with Cortical Cataract Formation in the Emory Mutant Mice

In vivo Phosphorylation of Lens Connexin 50 by Protein Kinase A Enhances Gap Junction and Hemichannel Function

Stimulation of Lens Cell Differentiation by Gap Junction Protein Connexin 45.6

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