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ARVO Annual Meeting Abstract June 2021

αB-Crystallin Potentiates Alzheimer’s Disease Aβ Neurotoxicity by Hetero-Oligomeric Stabilization

Juliet A Moncaster; Srikant Sarangi; Olga Minaeva; Xiao-lei Zhang; Robin Altman; Rajendra Gangalum; John Sullivan; Cidi Chen; Bertrand Huber; Ella Zeldich; Carmela Abraham; Suraj P Bhat; John Voss; Dean Hartley; Patric K Stanton; Lee E Goldstein

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2089. doi:

ARVO Annual Meeting Abstract July 2019

Absence of Single Cell Transcriptional Heterogeneity in the transgenic paradigm of the inherited Lamellar cataract

Suraj P Bhat; Rajendra K Gangalum; Dongjae Kim; Serghei Mangul; Raj K Kashyap; Xinkai Zhou; David Elashoff

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1381. doi:

ARVO Annual Meeting Abstract July 2019

Lamellar Cataract Transcriptome Analyses Suggest Developmental Delay in The Onset of the Differentiation Program in the Ocular Lens

Rajendra K Gangalum; Matthew Brooks; Dongjae Kim; Linn Gieser; Anand Swaroop; Suraj P Bhat

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4298. doi:

ARVO Annual Meeting Abstract July 2018

Serum Exposure of Human Retinal Pigment Epithelial (hRPE19) Cells Suggests Regulated Secretion of Various miRNAs via Exosomes

Rajendra K Gangalum; Dennis Mock; Dongjae Kim; Raj K Kashyap; Suraj P Bhat

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3064. doi:

ARVO Annual Meeting Abstract June 2017

The Small Heat Shock Protein αB-crystallin is Essential for the Organization of Detergent-Resistant Membrane Microdomains in Human Retinal Pigment Epithelial Cells in Culture

Rajendra K Gangalum; Dennis Mock; Ishanee Dighe; Karthik Ranganathan; Larry L David; Suraj P Bhat

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5234. doi:

ARVO Annual Meeting Abstract September 2016

Dissecting Exosome Biogenesis in Adult Human Retinal Pigment Epithelial Cells (ARPE19): Specific Interaction of αB-crystallin with Rab GTPase27b

Rajendra K Gangalum; Ankur M Bhat; Sirus A Kohan; Suraj P Bhat

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):245. doi:

ARVO Annual Meeting Abstract September 2016

aB-Crystallin expression in Alzheimer’s Disease brain in neuritic and diffuse plaques

Juliet A Moncaster; Rajendra K Gangalum; Olga Minaeva; John C Voss; Dean Hartley; Suraj P Bhat; Carmela Abraham; Bertrand R Huber; Patric K Stanton; Lee E Goldstein

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):730. doi:

ARVO Annual Meeting Abstract September 2016

Gene Expression Levels in Microsurgical Specimens from Patients with Glaucoma

Dennis Mock; Rajendra K Gangalum; Suraj P Bhat; Anne L Coleman

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6026. doi:

ARVO Annual Meeting Abstract September 2016

Gene Expression in Single Fiber Cells of the Ocular Lens: A window into molecular heterogeneity in a functional tissue

Suraj P Bhat; Rajendra K Gangalum; Dennis Mock

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract June 2015

αB-Crystallin interaction with Alzheimer’s Disease Amyloid-β potentiates Aβ-Mediated Neurotoxicity

Juliet A Moncaster; Thor Stein; Rajendra Gangalum; Srikant Sarangi; Olga Minaeva; Suraj P Bhat; John Voss; Carmela Abraham; Patric K Stanton; Lee E Goldstein

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5585. doi:

Lens November 2014

Expression of the HSF4 DNA Binding Domain-EGFP Hybrid Gene Recreates Early Childhood Lamellar Cataract in Transgenic Mice

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Rajendra K. Gangalum; Zhe Jing; Ankur M. Bhat; Josh Lee; Yoshiko Nagaoka; Sophie X. Deng; Meisheng Jiang; Suraj P. Bhat
TAGS: animals, transgenic, cataract, cell nucleus, child, dna, genes, lens (device), lens, crystalline, mice, mice, transgenic
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7227-7240. doi: https://doi.org/10.1167/iovs.14-14594

ARVO Annual Meeting Abstract April 2014

A DNA Binding Domain Mutation in HSF4 Found in Age- Related Cataract Patients and in Normal Populations Causes Lamellar Cataract in Transgenic Mice

Suraj P Bhat; Rajendra K Gangalum; Zhe Jing

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5039. doi:

ARVO Annual Meeting Abstract April 2014

αB-Crystallin Modulates Amyloid-β toxicity and impairs Synaptic Transmission

Juliet A Moncaster; Joy Ghosh; Rajendra K Gangalum; Tsuneya Ikezu; Ann McKee; John Voss; Carmela Abraham; Patric K Stanton; Suraj P Bhat; Lee E Goldstein

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4055. doi:

ARVO Annual Meeting Abstract March 2012

Expression of the Small Heat Shock Protein αB- crystallin is Controlled by a Gene-specific Sequence in its Promoter

Suraj P. Bhat; Zhe Jing; Rajendra K. Gangalum; Dennis Mock

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4147. doi:

ARVO Annual Meeting Abstract March 2012

Analysis of the Role of ZEB1 in the Pathogenesis of Posterior Polymorphous Corneal Dystrophy

Vivek S. Yellore; Rajendra K. Gangalum; Sylvia A. Rayner; Catherine K. Nguyen; Zhe Jing; Suraj P. Bhat; Anthony J. Aldave

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5983. doi:

Cornea January 2012

Analysis of the Role of ZEB1 in the Pathogenesis of Posterior Polymorphous Corneal Dystrophy

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Vivek S. Yellore; Sylvia A. Rayner; Catherine K. Nguyen; Rajendra K. Gangalum; Zhe Jing; Suraj P. Bhat; Anthony J. Aldave
TAGS: cornea, pathogenesis, polymorphous corneal dystrophy, promoter regions (genetics), proteins, rna, messenger, endothelial cells, reverse transcriptase polymerase chain reaction, corneal endothelium, adult
Invest. Ophthalmol. Vis. Sci.. 2012; 53(1):273-278. doi: https://doi.org/10.1167/iovs.11-8038

ARVO Annual Meeting Abstract April 2011

A Positional and Orientation Specific Sequence Controls Expression from the Heat Shock Promoter of αB-crystallin

Zhe Jing; Suraj P. Bhat

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):24. doi:

ARVO Annual Meeting Abstract April 2011

A free C-terminus is Essential for the Secretion of αB-crystallin via Exosomes in Human Adult Retinal Pigment Epithelial Cells in Culture

Rajendra K. Gangalum; Zhe Jing; Suraj P. Bhat

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3339. doi:

ARVO Annual Meeting Abstract April 2011

Recreation of Human Lamellar/Marner's cataract in Mice Employing Bacterial Artificial Chromosome (BAC) Transgenesis

Suraj P. Bhat; Rajendra K. Gangalum; Zhe Jing; Sophie X. Deng; Josh Lee

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2085. doi:

Lens July 2009

αB-crystallin: A Golgi-Associated Membrane Protein in the Developing Ocular Lens

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Rajendra K. Gangalum; Suraj P. Bhat
TAGS: crystallins, golgi apparatus, lens, crystalline, membrane proteins, lens (device)
Invest. Ophthalmol. Vis. Sci.. 2009; 50(7):3283-3290. doi: https://doi.org/10.1167/iovs.08-3052

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αB-Crystallin Potentiates Alzheimer’s Disease Aβ Neurotoxicity by Hetero-Oligomeric Stabilization

Absence of Single Cell Transcriptional Heterogeneity in the transgenic paradigm of the inherited Lamellar cataract

Lamellar Cataract Transcriptome Analyses Suggest Developmental Delay in The Onset of the Differentiation Program in the Ocular Lens

Serum Exposure of Human Retinal Pigment Epithelial (hRPE19) Cells Suggests Regulated Secretion of Various miRNAs via Exosomes

The Small Heat Shock Protein αB-crystallin is Essential for the Organization of Detergent-Resistant Membrane Microdomains in Human Retinal Pigment Epithelial Cells in Culture

Dissecting Exosome Biogenesis in Adult Human Retinal Pigment Epithelial Cells (ARPE19): Specific Interaction of αB-crystallin with Rab GTPase27b

aB-Crystallin expression in Alzheimer’s Disease brain in neuritic and diffuse plaques

Gene Expression Levels in Microsurgical Specimens from Patients with Glaucoma

Gene Expression in Single Fiber Cells of the Ocular Lens: A window into molecular heterogeneity in a functional tissue

αB-Crystallin interaction with Alzheimer’s Disease Amyloid-β potentiates Aβ-Mediated Neurotoxicity

Expression of the HSF4 DNA Binding Domain-EGFP Hybrid Gene Recreates Early Childhood Lamellar Cataract in Transgenic Mice

A DNA Binding Domain Mutation in HSF4 Found in Age- Related Cataract Patients and in Normal Populations Causes Lamellar Cataract in Transgenic Mice

αB-Crystallin Modulates Amyloid-β toxicity and impairs Synaptic Transmission

Expression of the Small Heat Shock Protein αB- crystallin is Controlled by a Gene-specific Sequence in its Promoter

Analysis of the Role of ZEB1 in the Pathogenesis of Posterior Polymorphous Corneal Dystrophy

Analysis of the Role of ZEB1 in the Pathogenesis of Posterior Polymorphous Corneal Dystrophy

A Positional and Orientation Specific Sequence Controls Expression from the Heat Shock Promoter of αB-crystallin

A free C-terminus is Essential for the Secretion of αB-crystallin via Exosomes in Human Adult Retinal Pigment Epithelial Cells in Culture

Recreation of Human Lamellar/Marner's cataract in Mice Employing Bacterial Artificial Chromosome (BAC) Transgenesis

αB-crystallin: A Golgi-Associated Membrane Protein in the Developing Ocular Lens

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