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ARVO Annual Meeting Abstract June 2024

Comparative Evaluation of Anti-Angiogenic Effects of Biosimilar Drugs in a DL-α-Aminoadipic Acid Rabbit Model of Chronic Vascular Leakage in Retina.

Donatas Neverauskas; Robertas Cesna; Symantas Ragauskas; Tomas Paulauskas; Giedrius Kalesnykas; Jeffrey Adam Jamison; Odeta Adamoniene

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):712.

ARVO Annual Meeting Abstract June 2024

Neural Network-based Isolectin B 4 Flat-Mount Analysis in a Novel AAV-hVEGF-Induced Diabetic Retinopathy Animal Model

Inesa Lelyte; Symantas Ragauskas; Marius Dragasius; Zubair Ahmed; Giedrius Kalesnykas; Nerija Kvietkauskiene

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2333.

ARVO Annual Meeting Abstract June 2024

Function-Structure Relationship in the Rat Glaucoma Model

Kernius Mickevicius; Tomas Paulauskas; Robertas Cesna; Marius Dragasius; Justina Urbanaviciute; Symantas Ragauskas; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6758.

ARVO Annual Meeting Abstract June 2023

Aflibercept exerts structural protection against diabetic retinopathy-associated inner retinal abnormalities in the mouse STZ model

Symantas Ragauskas; Tomas Paulauskas; Inesa Lelyte; Donatas Neverauskas; Kernius Mickevicius; Robertas Cesna; Giedrius Kalesnykas; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):556.

ARVO Annual Meeting Abstract June 2023

AAV-mediated expression of human VEGF-A as a novel rat model of diabetic retinopathy

Inesa Lelyte; Symantas Ragauskas; Tomas Paulauskas; Zubair Ahmed; Simon Kaja; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1820.

ARVO Annual Meeting Abstract June 2023

Involvement of thioredoxin system in laser induced CNV mouse model

Robertas Cesna; Dovile Litvinaviciute; Justina Urbanaviciute; Inesa Lelyte; Kernius Mickevicius; Odeta Adamoniene; Donatas Neverauskas; Symantas Ragauskas; Giedrius Kalesnykas; Anita K. Ghosh; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2727.

ARVO Annual Meeting Abstract June 2021

Validation of a novel artificial intelligence (AI) machine learning algorithm for quantification of vascular pathology in preclinical models

Jonas Jarutis; Simas Bijeikis; Symantas Ragauskas; Kernius Mickevicius; Giedrius Kalesnykas; Marc Cerrada-Gimenez; Simon Kaja; Nerija Kvietkauskiene

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2718.

ARVO Annual Meeting Abstract June 2021

Effects of chronic alcohol administration on the cornea in preclinical models

Anita K. Ghosh; Robertas Cesna; Agne Ziniauskaite; Donatas Neverauskas; Jonathan M Eby; Symantas Ragauskas; Simon Kaja

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1314.

ARVO Annual Meeting Abstract June 2020

Automated quantification of CNV volume using deep learning AI algorithm

Maria Vähätupa; Symantas Ragauskas; Agne Ziniauskaite; Anna Knuuttila; Hanna-Kaisa Sihvo; Mikael Jääskeläinen; Simon Kaja; Giedrius Kalesnykas; Marc Cerrada-Gimenez

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4194.

ARVO Annual Meeting Abstract June 2020

Comparative efficacy of bevacizumab and aflibercept in the rabbit DL-AAA model of chronic retinal neovascularization

Robertas Cesna; Tomas Paulauskas; Kernius Mickevicius; Donatas Neverauskas; Inesa Lelyte; Simon Kaja; Giedrius Kalesnykas; Symantas Ragauskas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5391.

ARVO Annual Meeting Abstract June 2020

Characterization of VEGF-induced retinal neovascularization in Dutch Belted rabbits using in vivo imaging.

Donatas Neverauskas; Kernius Mickevičius; Simon Kaja; Giedrius Kalesnykas; Symantas Ragauskas

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5399.

ARVO Annual Meeting Abstract July 2019

Standardization and validation of intravitreal and systemic administration of aflibercept in preclinical models for angiogenesis

Simon Kaja; Symantas Ragauskas; Maria Vähätupa; Marc Cerrada-Gimenez; Satu Mering; Jenni J. Hakkarainen; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1629.

Retina May 2019

Viability of Mouse Retinal Explant Cultures Assessed by Preservation of Functionality and Morphology

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Virpi Alarautalahti; Symantas Ragauskas; Jenni J. Hakkarainen; Hannele Uusitalo-Järvinen; Hannu Uusitalo; Jari Hyttinen; Giedrius Kalesnykas; Soile Nymark
TAGS: language morphology, mice, morphology, retina, tissue preparation, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):1914-1927. https://doi.org/10.1167/iovs.18-25156

ARVO Annual Meeting Abstract July 2018

Aflibercept shows strong dose-dependency when administered intravitreally in the mouse CNV model

Ruta Maciulaitiene; Symantas Ragauskas; Anna Mari Haapaniemi; Simon Kaja; Ingrida Januleviciene; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2631.

ARVO Annual Meeting Abstract July 2018

Utility of approved dry-eye drugs as reference compounds in SiccaSystem TM - a standardized mouse desiccating stress model for dry-eye disease

Simon Kaja; Symantas Ragauskas; Agne Ziniauskaite; Anna Mari Haapaniemi; Jenni J. Hakkarainen; Henna Martiskainen; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2673.

ARVO Annual Meeting Abstract July 2018

Neuroprotection of retinal ganglion cells via NMDA-dependent mechanism in the mouse non-arteritic anterior ischemic optic neuropathy (NAION) model

Symantas Ragauskas; Agne Ziniauskaite; Simon Kaja; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3204.

Cornea June 2018

Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome

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Agnė Žiniauskaitė; Symantas Ragauskas; Jenni J. Hakkarainen; Cadmus C. Rich; Rudolf Baumgartner; Giedrius Kalesnykas; David S. Albers; Simon Kaja
TAGS: cyclosporine, dry eye syndromes, eye, keratoconjunctivitis sicca, mice, pathology, syndrome, conjunctiva, goblet cells, cornea
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):3088-3093. https://doi.org/10.1167/iovs.18-24432

ARVO Annual Meeting Abstract June 2017

Assessment of the effects of systemically administered levetiracetam in an ocular model for neuroprotection.

Ruta Maciulaitiene; Symantas Ragauskas; Giedre Pakuliene; Simon Kaja; Ingrida Januleviciene; Giedrius Kalesnykas

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2571.

ARVO Annual Meeting Abstract September 2016

A topically delivered synthetic metalloporphyrin SOD mimetic improves hallmarks of dry-eye disease pathology.

Simon Kaja; Peter Koulen; Jooseppi Puranen; Symantas Ragauskas

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):396.

ARVO Annual Meeting Abstract September 2016

Age-related differences in light sensitivity in BALB/c mice

Giedrius Kalesnykas; Symantas Ragauskas; Simon Kaja; Heikki Tanila; Henri Olavi Leinonen

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5004.

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Comparative Evaluation of Anti-Angiogenic Effects of Biosimilar Drugs in a DL-α-Aminoadipic Acid Rabbit Model of Chronic Vascular Leakage in Retina.

Neural Network-based Isolectin B 4 Flat-Mount Analysis in a Novel AAV-hVEGF-Induced Diabetic Retinopathy Animal Model

Function-Structure Relationship in the Rat Glaucoma Model

Aflibercept exerts structural protection against diabetic retinopathy-associated inner retinal abnormalities in the mouse STZ model

AAV-mediated expression of human VEGF-A as a novel rat model of diabetic retinopathy

Involvement of thioredoxin system in laser induced CNV mouse model

Validation of a novel artificial intelligence (AI) machine learning algorithm for quantification of vascular pathology in preclinical models

Effects of chronic alcohol administration on the cornea in preclinical models

Automated quantification of CNV volume using deep learning AI algorithm

Comparative efficacy of bevacizumab and aflibercept in the rabbit DL-AAA model of chronic retinal neovascularization

Characterization of VEGF-induced retinal neovascularization in Dutch Belted rabbits using in vivo imaging.

Standardization and validation of intravitreal and systemic administration of aflibercept in preclinical models for angiogenesis

Viability of Mouse Retinal Explant Cultures Assessed by Preservation of Functionality and Morphology

Aflibercept shows strong dose-dependency when administered intravitreally in the mouse CNV model

Utility of approved dry-eye drugs as reference compounds in SiccaSystem TM - a standardized mouse desiccating stress model for dry-eye disease

Neuroprotection of retinal ganglion cells via NMDA-dependent mechanism in the mouse non-arteritic anterior ischemic optic neuropathy (NAION) model

Efficacy of Trabodenoson in a Mouse Keratoconjunctivitis Sicca (KCS) Model for Dry-Eye Syndrome

Assessment of the effects of systemically administered levetiracetam in an ocular model for neuroprotection.

A topically delivered synthetic metalloporphyrin SOD mimetic improves hallmarks of dry-eye disease pathology.

Age-related differences in light sensitivity in BALB/c mice

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