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ARVO Annual Meeting Abstract June 2024

PGC-1α mediated mitochondrial biogenesis promotes recovery and survival of neuronal cells from cellular degeneration

Wenting You; Chris P.M. Reutelingsperger; Tos Berendschot; Kèvin Knoops; Carroll Webers; Theo G M F Gorgels

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2570.

ARVO Annual Meeting Abstract June 2023

A Time Window for Rescuing Dying Retinal Ganglion Cells

Wenting You; Chris Reutelingsperger; Tos Berendschot; Kèvin Knoops; Carroll Webers; Theo G M F Gorgels

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1570.

Glaucoma August 2022

Wound Healing Response After Bleb-Forming Glaucoma Surgery With a SIBS Microshunt in Rabbits

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Ralph J. S. van Mechelen; Jarno E. J. Wolters; Marjolein Herfs; Christian J. F. Bertens; Marion Gijbels; Leonard Pinchuk; Theo G. M. F. Gorgels; Henny J. M. Beckers
TAGS: blister, glaucoma surgery, implantation procedure, oryctolagus cuniculus, wound healing, surgical procedures, operative
Trans. Vis. Sci. Tech.. 2022; 11(8):29. https://doi.org/10.1167/tvst.11.8.29

ARVO Annual Meeting Abstract June 2022

Reversible Mitochondrial Injury in Dying Retinal Ganglion Cells

Wenting You; Chris Reutelingsperger; Tos Berendschot; Carroll A. B. Webers; Theo G M F Gorgels

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2861 – A0384.

ARVO Annual Meeting Abstract June 2022

Reduced mitochondrial DNA copy number in peripheral blood lymphocytes of POAG patients

Antoni Vallbona Garcia; Ilse Hamers; Florence van Tienen; Irenaeus de Coo; Carroll A. B. Webers; Hubert Smeets; Theo G M F Gorgels

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2706 – A0070.

Glaucoma June 2021

Small RNA Sequencing of Aqueous Humor and Plasma in Patients With Primary Open-Angle Glaucoma

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Wouter H. G. Hubens; Julian Krauskopf; Henny J. M. Beckers; Jos C. S. Kleinjans; Carroll A. B. Webers; Theo G. M. F. Gorgels
TAGS: glaucoma, hypertension, micrornas, open-angle glaucoma, plasma, rna, small, aqueous humor, rna-seq, biological markers
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):24. https://doi.org/10.1167/iovs.62.7.24

Includes: Supplemental Content

Glaucoma April 2020

The Molecular Processes in the Trabecular Meshwork After Exposure to Corticosteroids and in Corticosteroid-Induced Ocular Hypertension

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Ilona Liesenborghs; Lars M. T. Eijssen; Martina Kutmon; Theo G. M. F. Gorgels; Chris T. Evelo; Henny J. M. Beckers; Carroll A. B. Webers; Johannes S. A. G. Schouten
TAGS: adrenal corticosteroids, cattle, datasets, dexamethasone, genes, glucocorticoids, mineralocorticoids, ocular hypertension, pathogenesis, trabecular meshwork
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):24. https://doi.org/10.1167/iovs.61.4.24

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

The signature of the healthy trabecular meshwork

Ilona Liesenborghs; Lars M.T. Eijssen; Martina Kutmon; Chris T. Evelo; Theo G.M.F. Gorgels; Wouter H.G. Hubens; Henny J Beckers; Carroll A.B. Webers; Jan S.A.G. Schouten

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3432.

ARVO Annual Meeting Abstract July 2019

Use of next-generation sequencing to identify microRNAs in aqueous humor and blood of primary open-angle glaucoma and cataract patients

Wouter H.G. Hubens; Julian Krauskopf; Florian Caiment; Henny J Beckers; Jos C.S. Kleinjans; Carroll A.B. Webers; Theo G.M.F. Gorgels

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5663.

ARVO Annual Meeting Abstract July 2019

Mapping mRNA expression of glaucoma genes in healthy mouse eyes

Theo G.M.F. Gorgels; Wouter H.G. Hubens; Wishal D. Ramdas; Carroll A.B. Webers

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6075.

ARVO Annual Meeting Abstract July 2019

Glaucoma-on-a-chip: an in vitro model for glaucoma drug discovery based on mimicking mechanical stress of high eye pressure

Pascal A.M.M. Vroemen; Ravi Sinha; Jeroen Rouwkema; Lorenzo Moroni; Jan de Boer; Carroll A.B. Webers; Theo G.M.F. Gorgels

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6170.

ARVO Annual Meeting Abstract June 2017

A bioinformatics approach to identify molecular pathways that characterize the trabecular meshwork

Ilona Liesenborghs; Carroll Webers; Lars Eijssen; Martina Kutmon; Theo G M F Gorgels; Wouter Hubens; Chris Evelo; Henny J Beckers; Johannes Schouten

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4904.

ARVO Annual Meeting Abstract June 2017

Molecular pathway analyses with bioinformatics in trabecular meshwork cells of patients with primary open angle glaucoma

Johannes Schouten; Ilona Liesenborghs; Lars Eijssen; Martina Kutmon; Theo G M F Gorgels; Chris Evelo; Henny J Beckers; Carroll Webers

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5625.

Retinal Cell Biology October 2013

Complement Factor C3a Alters Proteasome Function in Human RPE Cells and in an Animal Model of Age-Related RPE Degeneration

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J. Emanuel Ramos de Carvalho; Ingeborg Klaassen; Ilse M. C. Vogels; Sabine Schipper-Krom; Cornelis J. F. van Noorden; Eric Reits; Theo G. M. F. Gorgels; Arthur A. B. Bergen; Reinier O. Schlingemann
TAGS: complement system proteins, multicatalytic endopeptidase complex, retinal pigment cell, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2013; 54(10):6489-6501. https://doi.org/10.1167/iovs.13-12374

ARVO Annual Meeting Abstract March 2012

On the Origin of Proteins in Human Bruch’s Membrane and Drusen

Theo G. Gorgels; Judith C. Booij; Sovann Kaing; Imre Lengyel; Arthur A. Bergen

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6484.

ARVO Annual Meeting Abstract April 2011

Primary Open Angle Glaucoma: Gene Expression Profile and Functional Annotation of the Human Ciliary Body Epithelia

Sarah F. Janssen; Theo G. Gorgels; Jacoline B. ten Brink; Anke H. Essing; Nomdo M. Jansonius; Arthur A. Bergen

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4596.

ARVO Annual Meeting Abstract April 2010

A New Strategy to Identify and Annotate Human RPE-Specific Gene Expression

A. A. B. Bergen; J. B. ten Brink; S. M. Swagemakers; A. J. Verkerk; A. Essing; P. J. van der Spek; T. G. Gorgels; J. C. Booij

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):5974.

ARVO Annual Meeting Abstract April 2009

ERCC6 and the Risk of Age-related Macular Degeneration in two Study Populations from the Netherlands

T. G. Gorgels; D. D. G. Despriet; D. Baas; P. T. V. M. de Jong; J. R. Vingerling; C. C. W. Klaver; A. A. B. Bergen

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):3437.

ARVO Annual Meeting Abstract April 2009

Measuring Cell Death in Human RPE Cells Using Optical Coherence Tomography

D. M. de Bruin; M. Broekgaarden; T. Gorgels; T. G. van Leeuwen; D. J. Faber

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):5551.

ARVO Annual Meeting Abstract May 2008

Sensitivity Estimation of Nanoparticle Assisted Optical Molecular Imaging (NAOMI) Using Layered Retinal Tissue-Simulating Phantoms

D. M. de Bruin; D. J. Faber; T. Gorgels; F. Verbraak; T. G. van Leeuwen

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4806.

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PGC-1α mediated mitochondrial biogenesis promotes recovery and survival of neuronal cells from cellular degeneration

A Time Window for Rescuing Dying Retinal Ganglion Cells

Wound Healing Response After Bleb-Forming Glaucoma Surgery With a SIBS Microshunt in Rabbits

Reversible Mitochondrial Injury in Dying Retinal Ganglion Cells

Reduced mitochondrial DNA copy number in peripheral blood lymphocytes of POAG patients

Small RNA Sequencing of Aqueous Humor and Plasma in Patients With Primary Open-Angle Glaucoma

The Molecular Processes in the Trabecular Meshwork After Exposure to Corticosteroids and in Corticosteroid-Induced Ocular Hypertension

The signature of the healthy trabecular meshwork

Use of next-generation sequencing to identify microRNAs in aqueous humor and blood of primary open-angle glaucoma and cataract patients

Mapping mRNA expression of glaucoma genes in healthy mouse eyes

Glaucoma-on-a-chip: an in vitro model for glaucoma drug discovery based on mimicking mechanical stress of high eye pressure

A bioinformatics approach to identify molecular pathways that characterize the trabecular meshwork

Molecular pathway analyses with bioinformatics in trabecular meshwork cells of patients with primary open angle glaucoma

Complement Factor C3a Alters Proteasome Function in Human RPE Cells and in an Animal Model of Age-Related RPE Degeneration

On the Origin of Proteins in Human Bruch’s Membrane and Drusen

Primary Open Angle Glaucoma: Gene Expression Profile and Functional Annotation of the Human Ciliary Body Epithelia

A New Strategy to Identify and Annotate Human RPE-Specific Gene Expression

ERCC6 and the Risk of Age-related Macular Degeneration in two Study Populations from the Netherlands

Measuring Cell Death in Human RPE Cells Using Optical Coherence Tomography

Sensitivity Estimation of Nanoparticle Assisted Optical Molecular Imaging (NAOMI) Using Layered Retinal Tissue-Simulating Phantoms

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