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Retina May 2025

Exploring Therapeutic Targets for Age-Related Macular Degeneration From Circulating Proteins to Plasma Metabolites in the European Population

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Chengming Chen; Yanyan Lan; Weiming Yan; Xiaohong Zhang; Tian Li; Jing Han
TAGS: age-related macular degeneration, metabolites, plasma, proteins, european continental ancestry group
Trans. Vis. Sci. Tech.. 2025; 14(5):8. https://doi.org/10.1167/tvst.14.5.8

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging April 2025

Retinal Structure and Microcirculation Alterations in Patients With Papillary Thyroid Carcinoma: An Optical Coherence Tomography and Angiography Study

PDF

Yan-Jie Li; Zeng-Yu Zhang; Tian-Yue Liu; Hai-Yan Liu; Lu-Lu Shi; Rong-Xia Cao; Chao-Ran Lv; Zeng-Hui Zhang
TAGS: angiogram, fluid flow, microcirculation, optical coherence tomography, retina, thyroid carcinoma, papillary, carcinoma, perfusion, inflammation, inspection
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):73. https://doi.org/10.1167/iovs.66.4.73

Retina April 2025

Instrumenting Carotid Sonography Biomarkers and Polygenic Risk Score As a Novel Screening Approach for Retinal Detachment

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Kao-Jung Chang; Ching-Yun Wang; Hsin-Yu Wu; Pei-Yu Weng; Chia-Hsin Lu; Wei Chiu; Wei-Chieh Fang; Chong-En Kao; Cheng-Yi Li; Yi-Ting Chung; Yu-Chun Chen; Ai-Ru Hsieh; Shih-Hwa Chiou; Chih-Chien Hsu; Tai-Chi Lin; Shih-Jen Chen; De-Kuang Hwang
TAGS: biological markers, polygenic risk score, retinal detachment, screening, ultrasonography, hypertension
Trans. Vis. Sci. Tech.. 2025; 14(4):16. https://doi.org/10.1167/tvst.14.4.16

Includes: Supplemental Content

Cornea & External Disease April 2025

An Improved Monte Carlo Method for Quantitative Analysis of Transparency Degradation Caused by Corneal Edema

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Shuaiyi Li; Yiping Liu; Bao Yang; Sulei Lv; Xiulan Zou; Liqun Tang; Licheng Zhou; Zhenyu Jiang; Zejia Liu
TAGS: catabolism, cornea, corneal edema, monte carlo method, transparency, fibril
Trans. Vis. Sci. Tech.. 2025; 14(4):15. https://doi.org/10.1167/tvst.14.4.15

Visual Psychophysics and Physiological Optics March 2025

Age-Related Changes in Mesopic Reading Vision Across Adulthood

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Boris Peñaloza; Traci-Lin Goddin; David S. Friedman; Cynthia Owsley; MiYoung Kwon
TAGS: reading (activity), vision, adult
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):40. https://doi.org/10.1167/iovs.66.3.40

Glaucoma February 2025

Characterization, Enrichment, and Computational Modeling of Cross-Linked Actin Networks in Transformed Trabecular Meshwork Cells

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Haiyan Li; Devon H. Harvey; Jiannong Dai; Steven P. Swingle; Anthony M. Compton; Chenna Kesavulu Sugali; Kamesh Dhamodaran; Jing Yao; Tsai-Yu Lin; Todd Sulchek; Taeyoon Kim; C. Ross Ethier; Weiming Mao
TAGS: actins, adhesions, computer simulation, trabecular meshwork, cell nucleus, green fluorescent proteins, diagnostic imaging, incidence
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):65. https://doi.org/10.1167/iovs.66.2.65

Includes: Multimedia, Supplemental Content

Visual Neuroscience February 2025

OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis

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Natacha Stolowy; Lilija Gutmann; Margareta Lüpke; Thierry David; Michael Dorr; Christina Mayer; Christoph Heesen; Frederike Cosima Oertel; Ting-Yi Lin; Friedemann Paul; Hanna Gwendolyn Zimmermann; Jan-Patrick Stellmann
TAGS: multiple sclerosis, optic neuritis, retina, vision, visual impairment, eye, medical history
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):39. https://doi.org/10.1167/iovs.66.2.39

Includes: Supplemental Content

Retinal Cell Biology January 2025

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

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Qi Liu; Ling-Xiao Xia; Wan-Zhao Yi; Ya-Ni Wu; Shuo-Shuo Gu; Jian-Ying Chen; Ting-Ting Liu; Ying-Hui Lu; Yu-Hong Cui; Jing Meng; Hong-Wei Pan
TAGS: cyclin d1, endothelial cells, proto-oncogene proteins c-akt, retinal neovascularization, cell cycle, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):66. https://doi.org/10.1167/iovs.66.1.66

Includes: Supplemental Content

Lens January 2025

Influence of Lens Power on IOL/Posterior Lens Capsule Interactions and IOL's PCO Potential

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Amjad Chatila; Vicki Ea; Samira Izuagbe; Le Quynh Hoang; Bhavya Vaish; Cynthia M. Co; Trinh M. Luong; Liping Tang
TAGS: adhesions, diopters, incidence, lens (device), lens capsule, crystalline, lens, crystalline, myopia, eye
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):41. https://doi.org/10.1167/iovs.66.1.41

Includes: Supplemental Content

Clinical Trials December 2024

A New Approach to Retinal Oxygen Extraction Measurement Based on Laser Speckle Flowgraphy and Retinal Oximetry

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Viktoria Pai; Patrick Janku; Theresa Lindner; Ulrich Graf; Leopold Schmetterer; Gerhard Garhöfer; Doreen Schmidl
TAGS: lasers, oximetry, oxygen, oxygen extraction, oxygen saturation measurement, vascular flow, hypoxia, inspiration, respiration, hyperoxia
Trans. Vis. Sci. Tech.. 2024; 13(12):12. https://doi.org/10.1167/tvst.13.12.12

Retina December 2024

Choroidal and Choriocapillaris OCT-A Analysis in Patients Affected by Active Central Serous Chorioretinopathy

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Maria Ludovica Ruggeri; Marzia Passamonti; Alberto Quarta; Olgers Koci; Annamaria Porreca; Marta Di Nicola; Lucio Zeppa; Rodolfo Mastropasqua; Lisa Toto
TAGS: central serous chorioretinopathy
Trans. Vis. Sci. Tech.. 2024; 13(12):14. https://doi.org/10.1167/tvst.13.12.14

Genetics November 2024

Adult Onset Foveomacular Vitelliform Dystrophy Shows Genetic Overlap With Age-Related Macular Degeneration

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Shlomit Jaskoll; Adi Kramer; Sarah Elbaz-Hayoun; Batya Rinsky; Chiara M. Eandi; Michelle Grunin; Yahel Shwartz; Liran Tiosano; Iris M. Heid; Thomas Winkler; Itay Chowers
TAGS: adult, age-related macular degeneration, genetics, vitelliform dystrophy, complement system proteins, complement activation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):53. https://doi.org/10.1167/iovs.65.13.53

Includes: Supplemental Content

Low Vision Rehabilitation November 2024

Aligning Visual Prosthetic Development With Implantee Needs

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Lucas Nadolskis; Lily M. Turkstra; Ebenezer Larnyo; Michael Beyeler
TAGS: implants, research personnel, visual prosthesis
Trans. Vis. Sci. Tech.. 2024; 13(11):28. https://doi.org/10.1167/tvst.13.11.28

Includes: Supplemental Content

Glaucoma November 2024

Downregulation of SARM1 Protects Retinal Ganglion Cell Axonal and Somal Degeneration Via JNK Activation in a Glaucomatous Model of Ocular Hypertension

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Xuejin Zhang; Ting Li; Rong Zhang; Junfeng Li; Kaidi Wang; Jihong Wu
TAGS: axon, down-regulation, glaucoma, ocular hypertension, optic nerve, retina, retinal ganglion cells, tissue degeneration, wounds and injuries, injections
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):7. https://doi.org/10.1167/iovs.65.13.7

Includes: Supplemental Content

Glaucoma November 2024

Progressive Optic Neuropathy in Hydrocephalic Ccdc13 Mutant Mice Caused by Impaired Axoplasmic Transport at the Optic Nerve Head

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Mingjuan Wu; Xinyi Zhao; Shanzhen Peng; Xiaoyu Zhang; Jiali Ru; Lijing Xie; Tao Wen; Yingchun Su; Shujuan Xu; Dianlei Guo; Jianmin Hu; Haotian Lin; Tiansen Li; Chunqiao Liu
TAGS: axonal transport, mice, optic disk, optic nerve, optic nerve disorders, axon, retina, hydrocephalus
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):5. https://doi.org/10.1167/iovs.65.13.5

Includes: Supplemental Content

Retina October 2024

Preoperative Widefield Swept-Source Optical Coherence Tomography Versus Intraoperative Findings in Detecting Posterior Vitreous Detachment

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Zhuangling Lin; Kai Gao; Rebiya Tuxun; Chin-Ling Tsai; Zhuojun Xu; Lan Jiang; Yaping Liu; Ziye Chen; Zitong Chen; Baoyi Liu; Yuan Ma; Xiaoyue Wei; Kunbei Lai; Tao Li
TAGS: epiretinal membrane, intraoperative care, macular holes, optical coherence tomography, preoperative care, surgical procedures, operative, vitreous body, vitreous detachment, eye
Trans. Vis. Sci. Tech.. 2024; 13(10):39. https://doi.org/10.1167/tvst.13.10.39

Includes: Supplemental Content

Retina October 2024

Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

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Xiao Xie; Wenqi Wang; Hongyan Wang; Zhiping Zhang; Xiaomeng Yuan; Yanmei Shi; Yanfeng Liu; Qingjun Zhou; Tingting Liu
TAGS: artificial intelligence, biological markers, diabetes mellitus, type 2, diabetic nephropathy, perfusion, screening, random forest, complex
Trans. Vis. Sci. Tech.. 2024; 13(10):19. https://doi.org/10.1167/tvst.13.10.19

Clinical and Epidemiologic Research October 2024

Predictors of Discordance Between Dry Eye Symptoms and Signs: Insights From the Sjögren's International Collaborative Clinical Alliance

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Fanxiu Xiong; Benjamin F. Arnold; Thomas M. Lietman; John A. Gonzales
TAGS: dry eye syndromes, signs and symptoms, sjogren's syndrome, ocular signs and symptoms
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):3. https://doi.org/10.1167/iovs.65.12.3

Includes: Supplemental Content

Low Vision Rehabilitation October 2024

The Role of Season, Sunlight, and Light Sensitivity in Self-Reported Depressive Symptoms by Adults With Visual Impairment

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Rob T. M. van der Linden; Hilde P. A. van der Aa; Ruth M. A. van Nispen
TAGS: blindness, depressive disorders, photophobia, self-report, sunlight, visual impairment, mood, adult
Trans. Vis. Sci. Tech.. 2024; 13(10):2. https://doi.org/10.1167/tvst.13.10.2

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Categorization and naming of surface texture and color

Angela M. Brown; Delwin T. Lindsey

Journal of Vision. 2024; 24(10):891. https://doi.org/10.1167/jov.24.10.891

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Exploring Therapeutic Targets for Age-Related Macular Degeneration From Circulating Proteins to Plasma Metabolites in the European Population

Retinal Structure and Microcirculation Alterations in Patients With Papillary Thyroid Carcinoma: An Optical Coherence Tomography and Angiography Study

Instrumenting Carotid Sonography Biomarkers and Polygenic Risk Score As a Novel Screening Approach for Retinal Detachment

An Improved Monte Carlo Method for Quantitative Analysis of Transparency Degradation Caused by Corneal Edema

Age-Related Changes in Mesopic Reading Vision Across Adulthood

Characterization, Enrichment, and Computational Modeling of Cross-Linked Actin Networks in Transformed Trabecular Meshwork Cells

OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

Influence of Lens Power on IOL/Posterior Lens Capsule Interactions and IOL's PCO Potential

A New Approach to Retinal Oxygen Extraction Measurement Based on Laser Speckle Flowgraphy and Retinal Oximetry

Choroidal and Choriocapillaris OCT-A Analysis in Patients Affected by Active Central Serous Chorioretinopathy

Adult Onset Foveomacular Vitelliform Dystrophy Shows Genetic Overlap With Age-Related Macular Degeneration

Aligning Visual Prosthetic Development With Implantee Needs

Downregulation of SARM1 Protects Retinal Ganglion Cell Axonal and Somal Degeneration Via JNK Activation in a Glaucomatous Model of Ocular Hypertension

Progressive Optic Neuropathy in Hydrocephalic Ccdc13 Mutant Mice Caused by Impaired Axoplasmic Transport at the Optic Nerve Head

Preoperative Widefield Swept-Source Optical Coherence Tomography Versus Intraoperative Findings in Detecting Posterior Vitreous Detachment

Artificial Intelligence–Assisted Perfusion Density as Biomarker for Screening Diabetic Nephropathy

Predictors of Discordance Between Dry Eye Symptoms and Signs: Insights From the Sjögren's International Collaborative Clinical Alliance

The Role of Season, Sunlight, and Light Sensitivity in Self-Reported Depressive Symptoms by Adults With Visual Impairment

Categorization and naming of surface texture and color

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