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ARVO Annual Meeting Abstract June 2025

Application of Ultrawide Field (UWF) Swept Source Optical Coherence Tomography/Angiography (SS-OCT/OCTA) in Real-World Clinical Practice

Sandy Wenting Zhou; Gloria Wenjun Song; Hnin Hnin Oo; Wei Hing Seah; Yusra Asad; Tai Yong Loh; Peiqi Lo; Ser Koon Goh; Pavan Paniharam; Wenghang Wong; Nuo Tang; Qing Chang; Min Wang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):83.

ARVO Annual Meeting Abstract June 2025

A machine deep learning method to identify artifacts on ultra-wide field swept source optical coherence tomography angiography

Tai Yong Loh; Juling Sia; Sandy Wenting Zhou

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):557.

ARVO Annual Meeting Abstract June 2025

ARTIFICIAL INTELLIGENCE ASSISTED AUTOMATED GRADING OF A DIABETIC RETINOPATHY BIOMARKER OF NON-PERFUSION AREA USING ULTRA-WIDE FIELD SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

Wei Hing Seah; NUO TANG; Tai Yong Loh; Sandy Wenting Zhou

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):562.

ARVO Annual Meeting Abstract June 2025

Artificial Intelligence-based Automatic Identification of Diabetic Retinopathy Biomarker (IRMA) using Ultrawide Field Swept Source Optical Coherence Tomography Angiography

NUO TANG; Colin Ming hui Goh; Wei Hing Seah; Tai Yong Loh; Yue Qiu; Sandy Wenting Zhou; Qing Chang; Min Wang

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):95.

ARVO Annual Meeting Abstract June 2025

Comparing Diabetic Retinopathy Features In Various Fields Of View On An Ultra-Wide-Field Swept-Source Optical Coherence Tomography Angiography

Hnin Hnin Oo; Pavan Paniharam; Ser Koon Goh; Wei Hing Seah; Tai Yong Loh; Nuo Tang; Sandy Wenting Zhou

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):92.

ARVO Annual Meeting Abstract June 2025

Tcf4 suppression mitigates ECM dysregulation and guttae formation in a mouse model of Fuchs endothelial corneal dystrophy

Kotaro Onishi; Naoki Okumura; Suguru Ito; Taichi Yuasa; Ayaka Izumi; Albert S Jun; Yuki Oyama; Masahito Ikawa; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2959.

ARVO Annual Meeting Abstract June 2025

Generation and characterization of a mouse model for Fuchs endothelial corneal dystrophy harboring an intronic CTG trinucleotide repeat expansion in Tcf4

Tsutsumi Hayato; Naoki Okumura; Suguru Ito; Soichiro Inagaki; Ayaka Izumi; Taichi Yuasa; Yuki Oyama; Masahito Ikawa; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2956.

ARVO Annual Meeting Abstract June 2025

Investigation of Splicing Abnormalities in Fuchs Endothelial Corneal Dystrophy and Comparative Analysis with Myotonic Dystrophy Type 1

Taichi Yuasa; Naoki Okumura; Kurumi Yoshinaga; Yuichi Tokuda; Masakazu Nakano; Kei Tashiro; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):2953.

Cornea June 2025

Generation of a Mouse Model of Fuchs Endothelial Corneal Dystrophy by Knock-in of CTG Trinucleotide Repeat Expansion in the TCF4 Gene

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Yuki Oyama; Suguru Ito; Taichi Yuasa; Mizuki Ueda; Satoshi Chiba; Tatsuya Nakagawa; Ayaka Izumi; Masahito Ikawa; Noriko Koizumi; Naoki Okumura
TAGS: endothelium, genes, hereditary corneal dystrophy, mice, trinucleotide repeat expansion, cornea, sequence analysis, rna
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):18. https://doi.org/10.1167/iovs.66.6.18

Includes: Supplemental Content

Cornea April 2025

Heterozygous Tcf4 Deficiency Mitigates Fuchs Endothelial Corneal Dystrophy Progression in a Mouse Model

PDF

Suguru Ito; Yuki Oyama; Taichi Yuasa; Koki Amano; Kotaro Onishi; Ayaka Izumi; Albert S. Jun; Masahito Ikawa; Noriko Koizumi; Naoki Okumura
TAGS: cornea, endothelium, hereditary corneal dystrophy, heterozygote, mice, endothelial cells, genes
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):19. https://doi.org/10.1167/iovs.66.4.19

Includes: Supplemental Content

Cornea March 2025

The TCF4 Gene Regulates Apoptosis of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy

PDF

Tatsuya Nakagawa; Tetsuro Honda; Taichi Yuasa; Go Nishiuchi; Masakazu Sato; Ayumi Tokunaga; Makiko Nakahara; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Prema Padmanabhan; Amit Chatterjee; Gajanan Sathe; Vivek Ghose; Narayanan Janakiraman; Derek J. Blake; Noriko Koizumi; Sailaja Elchuri; Naoki Okumura
TAGS: apoptosis, cornea, endothelial cells, endothelium, genes, hereditary corneal dystrophy, pathogenesis, proteins, western blotting, liquid chromatography
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):16. https://doi.org/10.1167/iovs.66.3.16

Includes: Supplemental Content

Cornea June 2024

Dysregulation of the TCF4 Isoform in Corneal Endothelial Cells of Patients With Fuchs Endothelial Corneal Dystrophy

PDF

Tetsuro Honda; Tatsuya Nakagawa; Taichi Yuasa; Yuichi Tokuda; Masakazu Nakano; Kei Tashiro; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Koji Yamamoto; Noriko Koizumi; Naoki Okumura
TAGS: hereditary corneal dystrophy, protein isoforms, rna-seq, exons, cornea, endothelial cells, endothelium, datasets
Invest. Ophthalmol. Vis. Sci.. 2024; 65(6):27. https://doi.org/10.1167/iovs.65.6.27

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

The relationship between hemodynamics and structure is most strongly correlated in the temporal regions of the optic nerve in patients with primary open angle glaucoma

Lukas Ritzer; Alon Harris; Louis R. Pasquale; Brent A Siesky; Alice Chandra Verticchio Vercellin; Brendan Fry; George Eckert; Tak Yee Tania Tai; Anna Fabczak-Kubicka; Denise Alabi; Isaac Tessone; Michael Chang; Julia Arciero

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1232.

ARVO Annual Meeting Abstract June 2024

Doppler OCT assessed retinal venous blood flow is highly correlated with optic nerve and macular structure in patients with primary open angle glaucoma

Isaac Tessone; Alon Harris; Gal Antman; Alice Chandra Verticchio Vercellin; Brent A Siesky; Tak Yee Tania Tai; Luis Muncharaz Duran; Thomas A Ciulla; Lukas Ritzer; Michael Sidoti; Oscar Otero; Hernan Andres Rios; Masahiro Akiba; Kana Minamide; Richard B Rosen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1230.

ARVO Annual Meeting Abstract June 2024

Glaucoma Suspects Detection by Combined Machine Learning-Based Risk Score Generation and Feature Optimization

Alauddin Bhuiyan; James C Tsai; Tak Yee Tania Tai; Roland Theodore Smith; Arun Govindaiah

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1620.

ARVO Annual Meeting Abstract June 2024

Investigation of the TCF4 Aberrant Splicing in the Corneal Endothelial Cells of Patients with Fuchs Endothelial Corneal Dystrophy

Taichi Yuasa; Naoki Okumura; Tatsuya Nakagawa; Tetsuro Honda; Ayana Tateishi; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich E Kruse; Yuichi Tokuda; Masakazu Nakano; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5814.

ARVO Annual Meeting Abstract June 2024

Influence of visual field on visual acuity and contrast sensitivity of glaucomatous eyes with monofocal and diffractive extended depth-of-focus intraocular lenses

Keiichiro Minami; Yuka Ota; Yoko Taira; Hiroko Bissen-Miyajima; Ryo Takemura

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6337.

ARVO Annual Meeting Abstract June 2024

Prevalence and Risk Factors of Digital Eye Strain during the COVID-19 Pandemic in Taiwan

Yayu Chen; Yu-Chi Tai

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6022.

ARVO Annual Meeting Abstract June 2023

Comparison of Retinal Vascular Flow Parameters in Patients with Glaucoma and Vascular Retinopathy Using Doppler Optical Coherence Tomography

Hernan Andres Rios; Sofia Ahsanuddin; Oscar Otero-Marquez; Luis MuncharazDuran; Isaac Tessone; Gal Antman; Kana MINAMIDE; Alice Verticchio; Paul A Sidoti; Kateki Vinod; Tak Yee Tania Tai; Alon Harris; Toco Y. P. Chui; Masahiro Akiba; Richard B Rosen

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3250.

ARVO Annual Meeting Abstract June 2023

Choroidal thickness is lower in open angle glaucoma patients compared to healthy controls assessed by optical coherence tomography angiography

Anna Fabczak-Kubicka; Alon Harris; Brent A Siesky; Gal Antman; George Eckert; Paul A Sidoti; Rebecca Kellner; Thomas A Ciulla; Janet Constance Coleman-Belin; Francesco Oddone; Tak Yee Tania Tai; Alice Chandra Verticchio Vercellin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2568.

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Application of Ultrawide Field (UWF) Swept Source Optical Coherence Tomography/Angiography (SS-OCT/OCTA) in Real-World Clinical Practice

A machine deep learning method to identify artifacts on ultra-wide field swept source optical coherence tomography angiography

ARTIFICIAL INTELLIGENCE ASSISTED AUTOMATED GRADING OF A DIABETIC RETINOPATHY BIOMARKER OF NON-PERFUSION AREA USING ULTRA-WIDE FIELD SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

Artificial Intelligence-based Automatic Identification of Diabetic Retinopathy Biomarker (IRMA) using Ultrawide Field Swept Source Optical Coherence Tomography Angiography

Comparing Diabetic Retinopathy Features In Various Fields Of View On An Ultra-Wide-Field Swept-Source Optical Coherence Tomography Angiography

Tcf4 suppression mitigates ECM dysregulation and guttae formation in a mouse model of Fuchs endothelial corneal dystrophy

Generation and characterization of a mouse model for Fuchs endothelial corneal dystrophy harboring an intronic CTG trinucleotide repeat expansion in Tcf4

Investigation of Splicing Abnormalities in Fuchs Endothelial Corneal Dystrophy and Comparative Analysis with Myotonic Dystrophy Type 1

Generation of a Mouse Model of Fuchs Endothelial Corneal Dystrophy by Knock-in of CTG Trinucleotide Repeat Expansion in the TCF4 Gene

Heterozygous Tcf4 Deficiency Mitigates Fuchs Endothelial Corneal Dystrophy Progression in a Mouse Model

The TCF4 Gene Regulates Apoptosis of Corneal Endothelial Cells in Fuchs Endothelial Corneal Dystrophy

Dysregulation of the TCF4 Isoform in Corneal Endothelial Cells of Patients With Fuchs Endothelial Corneal Dystrophy

The relationship between hemodynamics and structure is most strongly correlated in the temporal regions of the optic nerve in patients with primary open angle glaucoma

Doppler OCT assessed retinal venous blood flow is highly correlated with optic nerve and macular structure in patients with primary open angle glaucoma

Glaucoma Suspects Detection by Combined Machine Learning-Based Risk Score Generation and Feature Optimization

Investigation of the TCF4 Aberrant Splicing in the Corneal Endothelial Cells of Patients with Fuchs Endothelial Corneal Dystrophy

Influence of visual field on visual acuity and contrast sensitivity of glaucomatous eyes with monofocal and diffractive extended depth-of-focus intraocular lenses

Prevalence and Risk Factors of Digital Eye Strain during the COVID-19 Pandemic in Taiwan

Comparison of Retinal Vascular Flow Parameters in Patients with Glaucoma and Vascular Retinopathy Using Doppler Optical Coherence Tomography

Choroidal thickness is lower in open angle glaucoma patients compared to healthy controls assessed by optical coherence tomography angiography

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