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Retina August 2021

Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma

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Linya Li; Shaoqing He; Yang Liu; Thomas Yorio; Dorette Z. Ellis
TAGS: caspase-3, glaucoma, mice, optic nerve, pentazocine, retinal ganglion cells, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):17. https://doi.org/10.1167/iovs.62.10.17

ARVO Annual Meeting Abstract June 2020

Endothelin-1 Induced Activation of Astrocytes and Changes in Their Subtype Markers

Shaoqing He; Vignesh Krishnamoorthy; Raghu R Krishnamoorthy; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):262.

ARVO Annual Meeting Abstract July 2019

Retinal Ganglion Cell Losses in an Optic Nerve Crush Model Correlate with Time-Dependent Up-Regulation in phosphorylated c-Jun, c-Jun and Caspase 3.

Dorette Z Ellis; Linya Li; Yang Liu; Shaoqing He; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):50.

Retina July 2019

Hybrid Compound SA-2 is Neuroprotective in Animal Models of Retinal Ganglion Cell Death

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Dorota L. Stankowska; Adnan Dibas; Linya Li; Wei Zhang; Vignesh R. Krishnamoorthy; Sai H. Chavala; Tam Phung Nguyen; Thomas Yorio; Dorette Z. Ellis; Suchismita Acharya
TAGS: animal model, electroretinography, eye, mice, neuroprotection, retina, retinal ganglion cells, wounds and injuries, hypoxia, ischemia
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3064-3073. https://doi.org/10.1167/iovs.18-25999

ARVO Annual Meeting Abstract July 2018

Astrocytes Promote Synapse Formation and Survival of Retinal Ganglion Cells at Early Phase During Endothelin Treatment

Shaoqing He; Hai-Ying Ma; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5291.

ARVO Annual Meeting Abstract July 2018

Activation of Sigma-1 Receptor Restores Retinal Ganglion Cell Losses in Optic Nerve Crush Model for Glaucoma.

Dorette Z Ellis; Linya Li; Yang Liu; Shaoqing He; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5296.

ARVO Annual Meeting Abstract July 2018

Bi-functional small molecule for glaucomatous optic neuropathy

Suchismita Acharya; Dorota L Stankowska; Renuka Makarand Chaphalkar; Linya Li; Dorette Z Ellis; Kytai T Nguyen; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5298.

Editorial March 2018

Thank You to Our Reviewers

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Thomas Yorio
TAGS: community, ophthalmology, peer review, vision, vision research
Invest. Ophthalmol. Vis. Sci.. 2018; 59(3):1538. https://doi.org/https://doi.org/10.1167/iovs.18-23983

ARVO Annual Meeting Abstract June 2017

Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASIC) in optic nerve crush model in rodents

Adnan Dibas; Dorota Stankowska; Brett Mueller; Oku Hidehiro; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3405.

ARVO Annual Meeting Abstract June 2017

Activation of Sigma-1 Receptor Protects Retinal Ganglion Cell Loss in Optic Nerve Crush Model for Glaucoma

Dorette Z Ellis; Linya Li; Shaoqing He; Yang Liu; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):212.

ARVO Annual Meeting Abstract June 2017

Interaction of Astrocytes and Retinal Ganglion Cells Following Endothelin Administration

Shaoqing He; Hai-Ying Ma; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):235.

Physiology and Pharmacology May 2017

Sigma-1 Receptor Regulates Mitochondrial Function in Glucose- and Oxygen-Deprived Retinal Ganglion Cells

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Dorette Z. Ellis; Linya Li; Yong Park; Shaoqing He; Brett Mueller; Thomas Yorio
TAGS: caspase-3, cytochrome c oxidase, glucose, mitochondria, oxygen, retinal ganglion cells, protein overexpression, pentazocine
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2755-2764. https://doi.org/10.1167/iovs.16-19199

ARVO Annual Meeting Abstract September 2016

Over Expression of Sigma-1 Receptor Protects Against Retinal Ganglion Cell loss in an Optic Nerve Crush Model

Dorette Z Ellis; Linya Li; Yang Liu; Yong H Park; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):85.

ARVO Annual Meeting Abstract September 2016

Increased expression of glucocorticoid receptor B induces a novel transforming growth factor beta-2 isoform in trabecular meshwork cells

Adnan Dibas; Abbot F Clark; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):86.

ARVO Annual Meeting Abstract September 2016

Endothelin-1 Induced the Reactivation of Primary Rat Ocular Astrocytes

Shaoqing He; Hai-Ying Ma; Yong H Park; Junming Wang; Thomas Yorio

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4211.

Editorial June 2016

Thank You to Our Reviewers

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Thomas Yorio
TAGS: ophthalmology, peer review, vision
Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):2966. https://doi.org/10.1167/iovs.16-19961

Physiology and Pharmacology February 2016

Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation

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Yong H. Park; Heather V. Broyles; Shaoqing He; Nolan R. McGrady; Linya Li; Thomas Yorio
TAGS: ampa receptors, glucose, oxygen, protein isoforms, retinal ganglion cells, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, rna, messenger, wounds and injuries, calcium
Invest. Ophthalmol. Vis. Sci.. 2016; 57(2):508-526. https://doi.org/10.1167/iovs.15-18481

Includes: Supplemental Content

Glaucoma September 2015

Endothelin-Mediated Changes in Gene Expression in Isolated Purified Rat Retinal Ganglion Cells

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Shaoqing He; Yong H. Park; Thomas Yorio; Raghu R. Krishnamoorthy
TAGS: endothelin-1, endothelin-3, endothelins, gene expression, genes, polymerase chain reaction, proteins, rna, messenger, retinal ganglion cells, endothelin-2
Invest. Ophthalmol. Vis. Sci.. 2015; 56(10):6144-6161. https://doi.org/10.1167/iovs.15-16569

Includes: Supplemental Content

Editorial August 2015

Open Access Coming to IOVS

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Thomas Yorio
TAGS: chief complaint, community, fees and charges, internet, journal impact factor, licensure, momentum, reading (activity), technology, vision
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5315. https://doi.org/10.1167/iovs.15-17823

ARVO Annual Meeting Abstract June 2015

Sigma-1 Receptor Increases Mitochondrial Membrane Potential in Glucose and Oxygen deprived Retinal Ganglion Cells.

Dorette Z Ellis; Linya Li; Yong H Park; Brett H Mueller; Hai-Ying Ma; Thomas Yorio; North Texas Eye Research Institute

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4258.

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Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma

Endothelin-1 Induced Activation of Astrocytes and Changes in Their Subtype Markers

Retinal Ganglion Cell Losses in an Optic Nerve Crush Model Correlate with Time-Dependent Up-Regulation in phosphorylated c-Jun, c-Jun and Caspase 3.

Hybrid Compound SA-2 is Neuroprotective in Animal Models of Retinal Ganglion Cell Death

Astrocytes Promote Synapse Formation and Survival of Retinal Ganglion Cells at Early Phase During Endothelin Treatment

Activation of Sigma-1 Receptor Restores Retinal Ganglion Cell Losses in Optic Nerve Crush Model for Glaucoma.

Bi-functional small molecule for glaucomatous optic neuropathy

Thank You to Our Reviewers

Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASIC) in optic nerve crush model in rodents

Activation of Sigma-1 Receptor Protects Retinal Ganglion Cell Loss in Optic Nerve Crush Model for Glaucoma

Interaction of Astrocytes and Retinal Ganglion Cells Following Endothelin Administration

Sigma-1 Receptor Regulates Mitochondrial Function in Glucose- and Oxygen-Deprived Retinal Ganglion Cells

Over Expression of Sigma-1 Receptor Protects Against Retinal Ganglion Cell loss in an Optic Nerve Crush Model

Increased expression of glucocorticoid receptor B induces a novel transforming growth factor beta-2 isoform in trabecular meshwork cells

Endothelin-1 Induced the Reactivation of Primary Rat Ocular Astrocytes

Thank You to Our Reviewers

Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation

Endothelin-Mediated Changes in Gene Expression in Isolated Purified Rat Retinal Ganglion Cells

Open Access Coming to IOVS

Sigma-1 Receptor Increases Mitochondrial Membrane Potential in Glucose and Oxygen deprived Retinal Ganglion Cells.

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