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ARVO Annual Meeting Abstract June 2023

Induced pluripotent stem cell derived retinal organoid sheets for regenerative therapy in patients with end-stage retinitis pigmentosa

Michiko Mandai; Yasuhiko Hirami; Sunao Sugita; Akiko Maeda; tadao Maeda; Midori Yamamoto; Hirofumi Uyama; Satoshi Yokota; Masashi Fujihara; Masataka Igeta; Takashi Daimon; Kanako Fujita; Tomoko Ito; Masayo Takahashi; Yasuo Kurimoto

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4628.

ARVO Annual Meeting Abstract April 2014

The paradoxical role of CCL3 in acute and chronic retinal degeneration

Hideo Kohno; Tsutomu Sakai; Tadao Maeda; Eric Pearlman; Krzysztof Palczewski; Akiko Maeda

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1254.

ARVO Annual Meeting Abstract April 2014

RPE cells differentiated from human induced pluripotent stem cells show production of the visual chromophore and phagocytosis ability

Akiko Maeda; Grazyna Palczewska; Hiroshi Maeno; Krzysztof Palczewski; Masayo Takahashi; Tadao Maeda

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1436.

ARVO Annual Meeting Abstract April 2014

Prophylactic Treatment of Optimized Retinylamine Loaded PLA Particles in a Macular Degeneration Mouse Model

Anthony Puntel; Akiko Maeda; Marcin Golczak; Tadao Maeda; Songqi Gao; Krzysztof Palczewski; Zheng-Rong Lu

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6000.

ARVO Annual Meeting Abstract June 2013

Molecular events for Bax activation in retinal cell death induced by all-trans-retinal

Osamu Sawada; Akiko Maeda; Shigemi Matsuyama; Tadao Maeda

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1779.

ARVO Annual Meeting Abstract June 2013

QLT091001, a 9-cis-retinal analog, is well tolerated by retinas of mice with impaired visual cycles

Tadao Maeda; Zhiqian Dong; Hui Jin; Osamu Sawada; Songqi Gao; Grazyna Palczewska; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6362.

Physiology and Pharmacology January 2013

QLT091001, a 9- cis -Retinal Analog, Is Well-Tolerated by Retinas of Mice with Impaired Visual Cycles

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Tadao Maeda; Zhiqian Dong; Hui Jin; Osamu Sawada; Songqi Gao; Deepank Utkhede; Wendy Monk; Grazyna Palczewska; Krzysztof Palczewski
TAGS: mice, retina, retinoids, diagnostic imaging, safety
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):455-466. https://doi.org/10.1167/iovs.12-11152

Physiology and Pharmacology September 2012

A Microparticle/Hydrogel Combination Drug-Delivery System for Sustained Release of Retinoids

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Song-Qi Gao; Tadao Maeda; Kiichiro Okano; Krzysztof Palczewski
TAGS: cell-derived microparticles, drug delivery systems, electroretinography, hydrogel, mice, retinoids, intravitreal injections, subcutaneous injections
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6314-6323. https://doi.org/10.1167/iovs.12-10279

ARVO Annual Meeting Abstract March 2012

Dysfunction Of Retinal Cells By All-trans-retinal And Its Condensation Product A2E

Tadao Maeda; kiichiro Okano; Yu Chen; Tsutomu Sakai; Krzysztof Palczewski; Akiko Maeda

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3357.

ARVO Annual Meeting Abstract March 2012

Subretinal Microglia/Macrophages Contribute To Retinal Degeneration Caused by All-trans-retinal

Hideo Kohno; Yu Chen; Tadao Maeda; Krzysztof Palczewski; Akiko Maeda

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3359.

ARVO Annual Meeting Abstract March 2012

Primary Amines Protect The Retina From Degeneration In Mouse Models: Implications For Stargardt’S Disease And Age-related Macular Degeneration

Akiko Maeda; Marcin Golczak; Yu Chen; Hideo Kohno; Grazyna Palczewska; Tadao Maeda; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2213.

ARVO Annual Meeting Abstract March 2012

Mechanism Of All-Trans-retinal Toxicity: Implications For Stargardt’S Disease And Age-related Macular Degeneration

Yu Chen; Kiichiro Okano; Tadao Maeda; Vishal Chauhan; Marcin Golczak; Akiko Maeda; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6469.

ARVO Annual Meeting Abstract March 2012

Genetically-related Inflammatory Priming and Failing Retinal Maintenance Predispose to Age-Related Retinal Degeneration in Mice

Debarshi Mustafi; Hideo Kohno; Krzysztof Palczewski; Tadao Maeda

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6510.

ARVO Annual Meeting Abstract March 2012

A mouse model of Retinitis Pigmentosa with an E150K mutation in the rod opsin gene

Ning Zhang; Osamu Sawada; Debarshi Mustafi; Tadao Maeda; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):746.

ARVO Annual Meeting Abstract April 2011

A Drug Delivery System for Sustained Release of 9-cis-Retinoids

Songqi Gao; Tadao Maeda; Kiichiro Okano; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3418.

ARVO Annual Meeting Abstract April 2011

Studies of Knockout Mice Provide Insight into the Retinal Significance of CYP27A1

Saida Omarova; Rachel E. Reem; Tadao Maeda; Casey Charvet; Wenchao Zheng; Akiko Maeda; Irina A. Pikuleva

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):950.

ARVO Annual Meeting Abstract April 2011

Unique Photoreceptor Cell Death Profile In All-trans-retinal-associated Retinal Degeneration

Tadao Maeda; Kiichiro Okano; Yu Chen; Vishal Chauhan; Grazyna Palczewska; Akiko Maeda; Krzysztof Palczewski

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):953.

Retina November 2009

Limited Roles of Rdh8, Rdh12, and Abca4 in all- trans -Retinal Clearance in Mouse Retina

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Akiko Maeda; Marcin Golczak; Tadao Maeda; Krzysztof Palczewski
TAGS: drug clearance, mice, retina, retinal degeneration, retinoids
Invest. Ophthalmol. Vis. Sci.. 2009; 50(11):5435-5443. https://doi.org/10.1167/iovs.09-3944

Retina October 2009

Evaluation of Potential Therapies for a Mouse Model of Human Age-Related Macular Degeneration Caused by Delayed all- trans -Retinal Clearance

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Tadao Maeda; Akiko Maeda; Melissa Matosky; Kiichiro Okano; Satsumi Roos; Johnny Tang; Krzysztof Palczewski
TAGS: age-related macular degeneration, drug clearance, mice, retinal degeneration, rapamycin
Invest. Ophthalmol. Vis. Sci.. 2009; 50(10):4917-4925. https://doi.org/10.1167/iovs.09-3581

Retina September 2009

Evaluation of 9- cis -Retinyl Acetate Therapy in Rpe65 −/− Mice

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Tadao Maeda; Akiko Maeda; Gemma Casadesus; Krzysztof Palczewski; Philippe Margaron
TAGS: mice, retinoids, acetates, vision
Invest. Ophthalmol. Vis. Sci.. 2009; 50(9):4368-4378. https://doi.org/10.1167/iovs.09-3700

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Induced pluripotent stem cell derived retinal organoid sheets for regenerative therapy in patients with end-stage retinitis pigmentosa

The paradoxical role of CCL3 in acute and chronic retinal degeneration

RPE cells differentiated from human induced pluripotent stem cells show production of the visual chromophore and phagocytosis ability

Prophylactic Treatment of Optimized Retinylamine Loaded PLA Particles in a Macular Degeneration Mouse Model

Molecular events for Bax activation in retinal cell death induced by all-trans-retinal

QLT091001, a 9-cis-retinal analog, is well tolerated by retinas of mice with impaired visual cycles

QLT091001, a 9- cis -Retinal Analog, Is Well-Tolerated by Retinas of Mice with Impaired Visual Cycles

A Microparticle/Hydrogel Combination Drug-Delivery System for Sustained Release of Retinoids

Dysfunction Of Retinal Cells By All-trans-retinal And Its Condensation Product A2E

Subretinal Microglia/Macrophages Contribute To Retinal Degeneration Caused by All-trans-retinal

Primary Amines Protect The Retina From Degeneration In Mouse Models: Implications For Stargardt’S Disease And Age-related Macular Degeneration

Mechanism Of All-Trans-retinal Toxicity: Implications For Stargardt’S Disease And Age-related Macular Degeneration

Genetically-related Inflammatory Priming and Failing Retinal Maintenance Predispose to Age-Related Retinal Degeneration in Mice

A mouse model of Retinitis Pigmentosa with an E150K mutation in the rod opsin gene

A Drug Delivery System for Sustained Release of 9-cis-Retinoids

Studies of Knockout Mice Provide Insight into the Retinal Significance of CYP27A1

Unique Photoreceptor Cell Death Profile In All-trans-retinal-associated Retinal Degeneration

Limited Roles of Rdh8, Rdh12, and Abca4 in all- trans -Retinal Clearance in Mouse Retina

Evaluation of Potential Therapies for a Mouse Model of Human Age-Related Macular Degeneration Caused by Delayed all- trans -Retinal Clearance

Evaluation of 9- cis -Retinyl Acetate Therapy in Rpe65 −/− Mice

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