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ARVO Annual Meeting Abstract July 2019

Decreased optic nerve head blood flow in acute retinal necrosis

Hiroshi Keino; Makiko Nakayama; Takayo Watanabe; Yoshimasa Ando; Takashi Koto; Kazunari Hirota; Makoto Inoue; Annabelle Okada

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):876. doi:

ARVO Annual Meeting Abstract July 2018

Endophthalmitis Rates of Ranibizumab in Pre-Filled Syringes Compared to Vials

Zujaja Tauqeer; Philip Storey; Jeremy D. Wolfe; Bozho Todorich; Ankoor R Shah; Takashi Koto; Ashkan Abbey; Yuki Morizane; Karen Jeng-Miller; Eric Chen; Patrick Williams; Fumio Shiraga; Akito Hirakata; Sunir Garg; Yoshihiro Yonekawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5697. doi:

ARVO Annual Meeting Abstract July 2018

Analyses of data in Japanese Retina and Vitreous Society registry on eyes with rhegmatogenous retinal detachments

Takayuki Baba; Taiji Sakamoto; Ryo Kawasaki; Akito Hirakata; Shuichi Yamamoto; Koichi Nishitsuka; Takashi Koto; Keita Yamakiri; Kazuaki Kadonosono; Masahito Ohji; Hidetoshi Yamashita; Yuichiro Ogura

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1834. doi:

ARVO Annual Meeting Abstract September 2016

Correlation of postoperative vision and fundus autofluorescence after vitrectomy for epiretinal membrane

Ryo Tokizawa; Makoto Inoue; Yoshiyuki Kita; Yuji Itoh; Takashi Koto; Akito Hirakata

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1091. doi:

Clinical and Epidemiologic Research March 2014

Association of Serum Lipids With Macular Thickness and Volume in Type 2 Diabetes Without Diabetic Macular Edema

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Mariko Sasaki; Motoko Kawashima; Ryo Kawasaki; Atsuro Uchida; Takashi Koto; Hajime Shinoda; Kazuo Tsubota; Jie Jin Wang; Yoko Ozawa
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic macular edema, lipids, volume, ldl cholesterol lipoproteins, risk factors, hemoglobin a, glycosylated
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1749-1753. doi: https://doi.org/10.1167/iovs.13-13035

ARVO Annual Meeting Abstract June 2013

Baseline characteristics and response to intravitreal ranibizumab therapy for age-related macular degeneration

Misa Suzuki; Norihiro Nagai; Kanako Izumi-Nagai; Hajime Shinoda; Takashi Koto; Atsuro Uchida; HIroshi Mochimaru; Kenya Yuki; Kazuo Tsubota; Yoko Ozawa; Laboratory of Retinal Cell Biology,Keio University Center for Integrated Medical Research

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4093. doi:

ARVO Annual Meeting Abstract June 2013

Associations of Serum Lipids with Macular Morphology in Patients without Diabetic Macular Edema

Mariko Sasaki; Motoko Kawashima; Ryo Kawasaki; Miho Kawai; Atsuro Uchida; Takashi Koto; Hajime Shinoda; Kazuo Tsubota; Jie Wang; Yoko Ozawa

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1237. doi:

ARVO Annual Meeting Abstract March 2012

Associations Between Early Signs Of Age-related Macular Degeneration (AMD) And Risk Of AMD In The Fellow Eye In Patients With Unilateral AMD

Mariko Sasaki; Ryo Kawasaki; Asturo Uchida; Takashi Koto; Hiroshi Mochimaru; Hajime Shinoda; Tien Y. Wong; Kazuo Tsubota; Yoko Ozawa

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6511. doi:

Retinal Cell Biology September 2009

Involvement of Hyaluronan and Its Receptor CD44 with Choroidal Neovascularization

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Hiroshi Mochimaru; Eri Takahashi; Nobuo Tsukamoto; Junichiro Miyazaki; Tomonori Yaguchi; Takashi Koto; Toshihide Kurihara; Kousuke Noda; Yoko Ozawa; Takatsugu Ishimoto; Yutaka Kawakami; Hidenobu Tanihara; Hideyuki Saya; Susumu Ishida; Kazuo Tsubota
TAGS: cd44 antigens, choroidal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2009; 50(9):4410-4415. doi: https://doi.org/10.1167/iovs.08-3044

Retinal Cell Biology October 2007

Suppression of Choroidal Neovascularization by Dendritic Cell Vaccination Targeting VEGFR2

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Hiroshi Mochimaru; Norihiro Nagai; Go Hasegawa; Chie Kudo-Saito; Tomonori Yaguchi; Yoshihiko Usui; Toshihide Kurihara; Takashi Koto; Shingo Satofuka; Hajime Shinoda; Yoko Ozawa; Kazuo Tsubota; Yutaka Kawakami; Susumu Ishida
TAGS: choroidal neovascularization, peptides, vaccination, dendritic cell vaccine, mice, t-lymphocytes
Invest. Ophthalmol. Vis. Sci.. 2007; 48(10):4795-4801. doi: https://doi.org/10.1167/iovs.07-0425

Retinal Cell Biology September 2007

Eicosapentaenoic Acid Is Anti-Inflammatory in Preventing Choroidal Neovascularization in Mice

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Takashi Koto; Norihiro Nagai; Hiroshi Mochimaru; Toshihide Kurihara; Kanako Izumi-Nagai; Shingo Satofuka; Hajime Shinoda; Kousuke Noda; Yoko Ozawa; Makoto Inoue; Kazuo Tsubota; Yuichi Oike; Susumu Ishida
TAGS: anti-inflammatory agents, choroidal neovascularization, mice, eicosapentaenoic acid, peroxisome proliferator-activated receptors, choroid, molecule
Invest. Ophthalmol. Vis. Sci.. 2007; 48(9):4328-4334. doi: https://doi.org/10.1167/iovs.06-1148

Retinal Cell Biology September 2007

Suppression of Diabetes-Induced Retinal Inflammation by Blocking the Angiotensin II Type 1 Receptor or Its Downstream Nuclear Factor-κB Pathway

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Norihiro Nagai; Kanako Izumi-Nagai; Yuichi Oike; Takashi Koto; Shingo Satofuka; Yoko Ozawa; Kenji Yamashiro; Makoto Inoue; Kazuo Tsubota; Kazuo Umezawa; Susumu Ishida
TAGS: diabetes mellitus, diabetes mellitus, type 2, inflammation, intercellular adhesion molecule 1, receptor, angiotensin, type 1, vascular endothelial growth factor a, leukocytes, retina
Invest. Ophthalmol. Vis. Sci.. 2007; 48(9):4342-4350. doi: https://doi.org/10.1167/iovs.06-1473

Retinal Cell Biology May 2007

Suppression of Choroidal Neovascularization by Inhibiting Angiotensin-Converting Enzyme: Minimal Role of Bradykinin

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Norihiro Nagai; Yuichi Oike; Kanako Izumi-Nagai; Takashi Koto; Shingo Satofuka; Hajime Shinoda; Kousuke Noda; Yoko Ozawa; Makoto Inoue; Kazuo Tsubota; Susumu Ishida
TAGS: choroidal neovascularization, angiotensin-converting enzyme, bradykinin, vascular endothelial growth factor a, intercellular adhesion molecule 1, monocyte chemoattractant protein-1
Invest. Ophthalmol. Vis. Sci.. 2007; 48(5):2321-2326. doi: https://doi.org/10.1167/iovs.06-1296

Retinal Cell Biology January 2007

Role of Nonproteolytically Activated Prorenin in Pathologic, but Not Physiologic, Retinal Neovascularization

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Shingo Satofuka; Atsuhiro Ichihara; Norihiro Nagai; Takashi Koto; Hajime Shinoda; Kousuke Noda; Yoko Ozawa; Makoto Inoue; Kazuo Tsubota; Hiroshi Itoh; Yuichi Oike; Susumu Ishida
TAGS: intercellular adhesion molecule 1, ischemia, retinal diseases, retinal neovascularization, vascular endothelial growth factor a, vascular endothelial growth factor receptor-2, vegfr-1, mice, proteins
Invest. Ophthalmol. Vis. Sci.. 2007; 48(1):422-429. doi: https://doi.org/10.1167/iovs.06-0534

Retinal Cell Biology June 2006

Suppression of Ocular Inflammation in Endotoxin-Induced Uveitis by Inhibiting Nonproteolytic Activation of Prorenin

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Shingo Satofuka; Atsuhiro Ichihara; Norihiro Nagai; Kenji Yamashiro; Takashi Koto; Hajime Shinoda; Kousuke Noda; Yoko Ozawa; Makoto Inoue; Kazuo Tsubota; Fumiaki Suzuki; Yuichi Oike; Susumu Ishida
TAGS: endotoxins, eye inflammation, intercellular adhesion molecule 1, interleukin-6, leukocytes, monocyte chemoattractant protein-1, proteins, uveitis, leukocyte cell adhesion
Invest. Ophthalmol. Vis. Sci.. 2006; 47(6):2686-2692. doi: https://doi.org/10.1167/iovs.05-1458

Retina October 2005

Hypoxia Induces the Expression of Membrane-Type 1 Matrix Metalloproteinase in Retinal Glial Cells

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Kousuke Noda; Susumu Ishida; Hajime Shinoda; Takashi Koto; Takanori Aoki; Kazuo Tsubota; Yoshihisa Oguchi; Yasunori Okada; Eiji Ikeda
TAGS: hypoxia, matrix metalloproteinases, neuroglia, vascular endothelial growth factor a, tissue membrane
Invest. Ophthalmol. Vis. Sci.. 2005; 46(10):3817-3824. doi: https://doi.org/10.1167/iovs.04-1528

Retina August 2005

Suppression of Ocular Inflammation in Endotoxin-Induced Uveitis by Blocking the Angiotensin II Type 1 Receptor

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Norihiro Nagai; Yuichi Oike; Kousuke Noda; Takashi Urano; Yoshiaki Kubota; Yoko Ozawa; Hajime Shinoda; Takashi Koto; Kei Shinoda; Makoto Inoue; Kazuo Tsubota; Kenji Yamashiro; Toshio Suda; Susumu Ishida
TAGS: endotoxins, eye inflammation, intercellular adhesion molecule 1, receptor, angiotensin, type 1, telmisartan, uveitis, proteins, mice, leukocytes
Invest. Ophthalmol. Vis. Sci.. 2005; 46(8):2925-2931. doi: https://doi.org/10.1167/iovs.04-1476

Retinal Cell Biology March 2005

Selective Suppression of Pathologic, but Not Physiologic, Retinal Neovascularization by Blocking the Angiotensin II Type 1 Receptor

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Norihiro Nagai; Kousuke Noda; Takashi Urano; Yoshiaki Kubota; Hajime Shinoda; Takashi Koto; Kei Shinoda; Makoto Inoue; Takayuki Shiomi; Eiji Ikeda; Kazuo Tsubota; Toshio Suda; Yuichi Oike; Susumu Ishida
TAGS: intercellular adhesion molecule 1, ischemia, receptor, angiotensin, type 1, retinal diseases, retinal neovascularization, telmisartan, vegfr-1, retina, mice
Invest. Ophthalmol. Vis. Sci.. 2005; 46(3):1078-1084. doi: https://doi.org/10.1167/iovs.04-1101

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Decreased optic nerve head blood flow in acute retinal necrosis

Endophthalmitis Rates of Ranibizumab in Pre-Filled Syringes Compared to Vials

Analyses of data in Japanese Retina and Vitreous Society registry on eyes with rhegmatogenous retinal detachments

Correlation of postoperative vision and fundus autofluorescence after vitrectomy for epiretinal membrane

Association of Serum Lipids With Macular Thickness and Volume in Type 2 Diabetes Without Diabetic Macular Edema

Baseline characteristics and response to intravitreal ranibizumab therapy for age-related macular degeneration

Associations of Serum Lipids with Macular Morphology in Patients without Diabetic Macular Edema

Associations Between Early Signs Of Age-related Macular Degeneration (AMD) And Risk Of AMD In The Fellow Eye In Patients With Unilateral AMD

Involvement of Hyaluronan and Its Receptor CD44 with Choroidal Neovascularization

Suppression of Choroidal Neovascularization by Dendritic Cell Vaccination Targeting VEGFR2

Eicosapentaenoic Acid Is Anti-Inflammatory in Preventing Choroidal Neovascularization in Mice

Suppression of Diabetes-Induced Retinal Inflammation by Blocking the Angiotensin II Type 1 Receptor or Its Downstream Nuclear Factor-κB Pathway

Suppression of Choroidal Neovascularization by Inhibiting Angiotensin-Converting Enzyme: Minimal Role of Bradykinin

Role of Nonproteolytically Activated Prorenin in Pathologic, but Not Physiologic, Retinal Neovascularization

Suppression of Ocular Inflammation in Endotoxin-Induced Uveitis by Inhibiting Nonproteolytic Activation of Prorenin

Hypoxia Induces the Expression of Membrane-Type 1 Matrix Metalloproteinase in Retinal Glial Cells

Suppression of Ocular Inflammation in Endotoxin-Induced Uveitis by Blocking the Angiotensin II Type 1 Receptor

Selective Suppression of Pathologic, but Not Physiologic, Retinal Neovascularization by Blocking the Angiotensin II Type 1 Receptor

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