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ARVO Annual Meeting Abstract July 2019

A new method for en Face confocal imaging of Schlemm’s canal inner wall and juxtacanalicular trabecular meshwork

Mini Aga; John Bradley; Janice A Vranka; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5123. doi:

ARVO Annual Meeting Abstract July 2019

Media borne factor that stimulates stem cell division following laser trabeculoplasty

Samuel J Berk; Lindsay Peterkin; Shandiz Tehrani; Ted S Acott; Mary J Kelley

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5153. doi:

ARVO Annual Meeting Abstract July 2018

Collector Channel Dynamics: OCT Capture of Real-time Pressure-dependent Changes in Lumen Area in Ex Vivo Normal and Glaucomatous Eyes

Murray A Johnstone; C Ross Ethier; Ted S Acott; Janice Vranka; Steven J Padilla; Kimika Wen; Chen Xin; Lei Zhang; Shaozhen SONG; Ruikang K Wang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5907. doi:

ARVO Annual Meeting Abstract July 2018

Substrate stiffness triggers an extracellular matrix response in human trabecular meshwork cells and tissues

Janice A Vranka; Julia Staverosky; Ying Ying Sun; Yong-Feng Yang; John Bradley; Kate E Keller; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4722. doi:

ARVO Annual Meeting Abstract July 2018

Homeostatic Role for GPR158 in Modulating Intraocular Pressure (IOP)

Tatsuo Itakura; Andrew Webster; Jose M Gonzalez; James C H Tan; Maria Sibug-Saber; Cheryl Mae Craft; Janice A Vranka; Ted S Acott; W Daniel Stamer; Kirill A Martemyanov; M Elizabeth Fini

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4724. doi:

ARVO Annual Meeting Abstract July 2018

Integrin α7-β1 heterodimer as a mechanosensor in the trabecular meshwork

Julia A Staverosky; Ted S Acott; Janice A Vranka

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4725. doi:

ARVO Annual Meeting Abstract July 2018

Connexin43 is a key element for differentiation of iPSCs to trabecular meshwork like cells

Xinbo Li; Yufeng Wang; Davey Li; Ted S Acott; Mary J Kelley

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3530. doi:

Biochemistry and Molecular Biology January 2018

Biomechanical Rigidity and Quantitative Proteomics Analysis of Segmental Regions of the Trabecular Meshwork at Physiologic and Elevated Pressures

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Janice A. Vranka; Julia A. Staverosky; Ashok P. Reddy; Phillip A. Wilmarth; Larry L. David; Ted S. Acott; Paul Russell; Vijay Krishna Raghunathan
TAGS: heart failure, biomechanics, muscle rigidity, body tissue, trabecular meshwork, pressure-physical agent, proteins, proteomics, fluid flow
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):246-259. doi: 10.1167/iovs.17-22759

Includes: Supplemental Content

Glaucoma October 2017

Tunneling Nanotubes are Novel Cellular Structures That Communicate Signals Between Trabecular Meshwork Cells

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Kate E. Keller; John M. Bradley; Ying Ying Sun; Yong-Feng Yang; Ted S. Acott
TAGS: actins, mitochondria, cd44 antigens, cellular structures, dimethyl sulfoxide, microscopy, confocal, software, body tissue, trabecular meshwork, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5298-5307. doi: 10.1167/iovs.17-22732

Includes: Supplemental Content

Glaucoma September 2017

Estimating Human Trabecular Meshwork Stiffness by Numerical Modeling and Advanced OCT Imaging

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Ke Wang; Murray A. Johnstone; Chen Xin; Shaozhen Song; Steven Padilla; Janice A. Vranka; Ted S. Acott; Kai Zhou; Stephen A. Schwaner; Ruikang K. Wang; Todd Sulchek; C. Ross Ethier
TAGS: glaucoma, body tissue, trabecular meshwork, diagnostic imaging, eye, sclera, orthopedic footwear, wedges
Invest. Ophthalmol. Vis. Sci.. 2017; 58(11):4809-4817. doi: 10.1167/iovs.17-22175

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract September 2016

Gap and tight intercellular junctions in trabecular meshwork and Schlemm’s canal cells

Xinbo Li; Ted S Acott; Mary J Kelley

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4678. doi:

ARVO Annual Meeting Abstract September 2016

The role of Myosin-X in tunneling nanotube formation by trabecular meshwork cells

Kate E Keller; John Bradley; Ying Ying Sun; Yong-feng Yang; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4691. doi:

ARVO Annual Meeting Abstract September 2016

Novel extracellular protein kinases Fam20A and Fam20C differentially distribute with MMP14 at PILS in TM cells

Mini Aga; Samuel J Berk; John M Bradley; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4701. doi:

ARVO Annual Meeting Abstract September 2016

Biomechanical Rigidity and Proteomics Analyses of Segmental Outflow Regions of the Trabecular Meshwork at Physiologic and Elevated Pressures

Janice A Vranka; Vijaykrishna Raghunathan; Paul Russell; Kate E Keller; Ashok Reddy; Phillip Wilmarth; John Klimek; Larry L. David; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4702. doi:

ARVO Annual Meeting Abstract September 2016

Trabecular Meshwork EMC in Glaucoma

Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract June 2015

Unidirectional transfer of cellular cargo between trabecular meshwork cells via novel actin-based filopodia

Kate E Keller; John M Bradley; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3265. doi:

ARVO Annual Meeting Abstract June 2015

Involvement of ATP binding cassette transporter 1 (ABCA1) in the regulation of outflow facility

Xinbo Li; Kevin Phan; Ted S Acott; Mary J Kelley

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3282. doi:

ARVO Annual Meeting Abstract June 2015

Matrix metalloproteinase-14 dimerization orchestrates matrix degradation at podosome- or invadopodia-like structures (PILS) in trabecular meshwork.

Mini Aga; John M Bradley; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3283. doi:

Glaucoma September 2014

Differential Effects of Caveolin-1 and -2 Knockdown on Aqueous Outflow and Altered Extracellular Matrix Turnover in Caveolin-Silenced Trabecular Meshwork Cells

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Mini Aga; John M. Bradley; Rohan Wanchu; Yong-feng Yang; Ted S. Acott; Kate E. Keller
TAGS: extracellular matrix, fibronectins, caveolins, genes, lentivirus, matrix metalloproteinases, perfusion, trabecular meshwork, proteins, catabolism
Invest. Ophthalmol. Vis. Sci.. 2014; 55(9):5497-5509. doi: 10.1167/iovs.14-14519

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Restoration of Trabecular Meshwork Functions

Mary J Kelley; Diala W Abu-Hassan; Xinbo Li; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5672. doi:

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A new method for en Face confocal imaging of Schlemm’s canal inner wall and juxtacanalicular trabecular meshwork

Media borne factor that stimulates stem cell division following laser trabeculoplasty

Collector Channel Dynamics: OCT Capture of Real-time Pressure-dependent Changes in Lumen Area in Ex Vivo Normal and Glaucomatous Eyes

Substrate stiffness triggers an extracellular matrix response in human trabecular meshwork cells and tissues

Homeostatic Role for GPR158 in Modulating Intraocular Pressure (IOP)

Integrin α7-β1 heterodimer as a mechanosensor in the trabecular meshwork

Connexin43 is a key element for differentiation of iPSCs to trabecular meshwork like cells

Biomechanical Rigidity and Quantitative Proteomics Analysis of Segmental Regions of the Trabecular Meshwork at Physiologic and Elevated Pressures

Tunneling Nanotubes are Novel Cellular Structures That Communicate Signals Between Trabecular Meshwork Cells

Estimating Human Trabecular Meshwork Stiffness by Numerical Modeling and Advanced OCT Imaging

Gap and tight intercellular junctions in trabecular meshwork and Schlemm’s canal cells

The role of Myosin-X in tunneling nanotube formation by trabecular meshwork cells

Novel extracellular protein kinases Fam20A and Fam20C differentially distribute with MMP14 at PILS in TM cells

Biomechanical Rigidity and Proteomics Analyses of Segmental Outflow Regions of the Trabecular Meshwork at Physiologic and Elevated Pressures

Trabecular Meshwork EMC in Glaucoma

Unidirectional transfer of cellular cargo between trabecular meshwork cells via novel actin-based filopodia

Involvement of ATP binding cassette transporter 1 (ABCA1) in the regulation of outflow facility

Matrix metalloproteinase-14 dimerization orchestrates matrix degradation at podosome- or invadopodia-like structures (PILS) in trabecular meshwork.

Differential Effects of Caveolin-1 and -2 Knockdown on Aqueous Outflow and Altered Extracellular Matrix Turnover in Caveolin-Silenced Trabecular Meshwork Cells

Restoration of Trabecular Meshwork Functions

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