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ARVO Annual Meeting Abstract June 2022

RNA-Seq based transcriptome analysis of corneal endothelial cells derived from the patients with Fuchs endothelial corneal dystrophy

Tatsuya Nakagawa; Naoki Okumura; Yuya Komori; Naoya Hanada; Yuichi Tokuda; Masakazu Nakano; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2278. doi:

ARVO Annual Meeting Abstract June 2021

Deep neural network by transfer learning for the analysis of guttae in the patients with Fuchs endothelial corneal dystrophy

Kaito Narimoto; Naoki Okumura; Shohei Yamada; Kengo Okamura; Ayaka Izumi; Theofilos Tourtas; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):817. doi:

ARVO Annual Meeting Abstract June 2021

Proteomic analysis of TCF4 knock-out corneal endothelial cells derived from the patients with Fuchs endothelial corneal dystrophy

Tatsuya Nakagawa; Naoki Okumura; Naoya Hanada; Prema Padmanabhan; Sailaja Elchuri; Amit Chatterjee; Narayanan Janakiraman; Gajanan Sathe; Vivek Ghose; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):827. doi:

ARVO Annual Meeting Abstract June 2020

Effect of CTG repeat expansion in TCF4 on the pathophysiology of Fuchs endothelial corneal dystrophy

Hinata Matsuo; Naoki Okumura; Yuya Komori; Ayumi Tokunaga; Genta Nakayama; Makiko Nakahara; Derek J Blake; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1186. doi:

ARVO Annual Meeting Abstract July 2019

Potential functional restoration of corneal endothelial cells in Fuchs corneal dystrophy by ROCK inhibitor (Ripasudil)

Friedrich E Kruse; Theofilos Tourtas; Matthias Zenkel; Shigeru Kinoshita; Ursula Schlotzer-Schrehardt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2172. doi:

ARVO Annual Meeting Abstract July 2019

Involvement of a disintegrin and metalloproteinase 10 (ADAM10) in excessive extracellular matrix production in Fuchs endothelial corneal dystrophy

Yuya Komori; Naoki Okumura; Naoya Hanada; Ayumi Tokunaga; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2175. doi:

ARVO Annual Meeting Abstract July 2019

Involvement of caspase 7 in the excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy

Shigehito Tonomura; Naoki Okumura; Mako Endo; Makiko Nakahara; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2176. doi:

ARVO Annual Meeting Abstract July 2019

Drug discovery for the treatment of Fuchs corneal endothelial dystrophy by cell-based drug screening system

Risako Nakagawa; Naoki Okumura; Takako Onishi; Takeshi Oshima; Emi Ueda; Kyoko Watanabe; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3877. doi:

ARVO Annual Meeting Abstract July 2019

Feasibility of mTOR inhibitor for the treatment of Fuchs endothelial corneal dystrophy

Genta Nakayama; Naoki Okumura; Takeshi Oshima; Emi Ueda; Kyoko Watanabe; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3878. doi:

ARVO Annual Meeting Abstract July 2019

Delayed corneal clearance after uneventful Descemet Membrane endothelial keratoplasty

Victor A Augustin; Julia M Weller; Friedrich E Kruse; Theofilos Tourtas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6285. doi:

ARVO Annual Meeting Abstract July 2019

Supplementation of amphotericin B in Optisol-GS for Descemet membrane endothelial keratoplasty (DMEK)

Maria Elena Galimi; Julia M Weller; Friedrich E Kruse; Victor A Augustin; Theofilos Tourtas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6300. doi:

Cornea February 2019

Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy

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Naoki Okumura; Ryosuke Hayashi; Masakazu Nakano; Kengo Yoshii; Kei Tashiro; Takahiko Sato; Derek J. Blake; Ross Aleff; Malinda Butz; Edward W. Highsmith; Eric D. Wieben; Michael P. Fautsch; Keith H. Baratz; Yuya Komori; Makiko Nakahara; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Noriko Koizumi
TAGS: corneal endothelium, endothelium, hereditary corneal dystrophy, rna, messenger, trinucleotide repeat expansion, dna, genome, polymerase chain reaction, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):779-786. doi: https://doi.org/10.1167/iovs.18-25760

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Influence of Fuchs endothelial corneal dystrophy on contrast sensitivity in cataract patients

Theofilos Tourtas; Victor A Augustin; Julia Weller; Friedrich E Kruse

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1311. doi:

ARVO Annual Meeting Abstract July 2018

Can we optimize the refractive target in triple Descemet membrane endothelial keratoplasty in the fellow eye after surgery in the first eye?

Victor A Augustin; Julia Weller; Friedrich E Kruse; Theofilos Tourtas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1326. doi:

ARVO Annual Meeting Abstract July 2018

Association of rs613872 and trinucleotide repeat expansion in the TCF4 gene in Fuchs endothelial corneal dystrophy in Germany

Yuya Komori; Naoki Okumura; Ryosuke Hayashi; Masakazu Nakano; Kei Tashiro; Kengo Yoshii; Ross Aleff; Malinda Butz; Edward W. Highsmith; Eric Wieben; Michael P. Fautsch; Keith H Baratz; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1353. doi:

ARVO Annual Meeting Abstract July 2018

Establishment of a drug screening system for Fuchs endothelial corneal dystrophy

Takeshi Oshima; Naoki Okumura; Takako Onishi; Emi Ueda; Kyoko Watanabe; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1354. doi:

Cornea July 2017

Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy

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Naoki Okumura; Miu Kitahara; Hirokazu Okuda; Keisuke Hashimoto; Emi Ueda; Makiko Nakahara; Shigeru Kinoshita; Robert D. Young; Andrew J. Quantock; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Noriko Koizumi
TAGS: cell death, cornea, corneal endothelium, endothelium, hereditary corneal dystrophy, mitochondria, proteins, stress, unfolded protein response, cyclophosphamide, doxorubicin, prednisone, and vincristine
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3697-3707. doi: https://doi.org/10.1167/iovs.16-21023

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Feasibility of TGF-β inhibition for the treatment of Fuchs endothelial corneal dystrophy

Naoki Okumura; Keisuke Hashimoto; Hirokazu Okuda; Emi Ueda; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1434. doi:

ARVO Annual Meeting Abstract June 2017

Feasibility of caspase inhibitor to treat Fuchs endothelial corneal dystrophy

Mako Endo; Naoki Okumura; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1436. doi:

ARVO Annual Meeting Abstract June 2017

Expression level of the TCF4 gene in the corneal endothelium of Fuchs endothelial corneal dystrophy patients

Ryosuke Hayashi; Naoki Okumura; Keisuke Ogata; Masakazu Nakano; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1438. doi:

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RNA-Seq based transcriptome analysis of corneal endothelial cells derived from the patients with Fuchs endothelial corneal dystrophy

Deep neural network by transfer learning for the analysis of guttae in the patients with Fuchs endothelial corneal dystrophy

Proteomic analysis of TCF4 knock-out corneal endothelial cells derived from the patients with Fuchs endothelial corneal dystrophy

Effect of CTG repeat expansion in TCF4 on the pathophysiology of Fuchs endothelial corneal dystrophy

Potential functional restoration of corneal endothelial cells in Fuchs corneal dystrophy by ROCK inhibitor (Ripasudil)

Involvement of a disintegrin and metalloproteinase 10 (ADAM10) in excessive extracellular matrix production in Fuchs endothelial corneal dystrophy

Involvement of caspase 7 in the excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy

Drug discovery for the treatment of Fuchs corneal endothelial dystrophy by cell-based drug screening system

Feasibility of mTOR inhibitor for the treatment of Fuchs endothelial corneal dystrophy

Delayed corneal clearance after uneventful Descemet Membrane endothelial keratoplasty

Supplementation of amphotericin B in Optisol-GS for Descemet membrane endothelial keratoplasty (DMEK)

Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy

Influence of Fuchs endothelial corneal dystrophy on contrast sensitivity in cataract patients

Can we optimize the refractive target in triple Descemet membrane endothelial keratoplasty in the fellow eye after surgery in the first eye?

Association of rs613872 and trinucleotide repeat expansion in the TCF4 gene in Fuchs endothelial corneal dystrophy in Germany

Establishment of a drug screening system for Fuchs endothelial corneal dystrophy

Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy

Feasibility of TGF-β inhibition for the treatment of Fuchs endothelial corneal dystrophy

Feasibility of caspase inhibitor to treat Fuchs endothelial corneal dystrophy

Expression level of the TCF4 gene in the corneal endothelium of Fuchs endothelial corneal dystrophy patients

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