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ARVO Annual Meeting Abstract June 2020

Effect of CTG repeat expansion in TCF4 on the pathophysiology of Fuchs endothelial corneal dystrophy

Hinata Matsuo; Naoki Okumura; Yuya Komori; Ayumi Tokunaga; Genta Nakayama; Makiko Nakahara; Derek J Blake; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1186. doi:

ARVO Annual Meeting Abstract July 2019

Delayed corneal clearance after uneventful Descemet Membrane endothelial keratoplasty

Victor A Augustin; Julia M Weller; Friedrich E Kruse; Theofilos Tourtas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6285. doi:

ARVO Annual Meeting Abstract July 2019

Supplementation of amphotericin B in Optisol-GS for Descemet membrane endothelial keratoplasty (DMEK)

Maria Elena Galimi; Julia M Weller; Friedrich E Kruse; Victor A Augustin; Theofilos Tourtas

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6300. doi:

ARVO Annual Meeting Abstract July 2019

Potential functional restoration of corneal endothelial cells in Fuchs corneal dystrophy by ROCK inhibitor (Ripasudil)

Friedrich E Kruse; Theofilos Tourtas; Matthias Zenkel; Shigeru Kinoshita; Ursula Schlotzer-Schrehardt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2172. doi:

ARVO Annual Meeting Abstract July 2019

Involvement of a disintegrin and metalloproteinase 10 (ADAM10) in excessive extracellular matrix production in Fuchs endothelial corneal dystrophy

Yuya Komori; Naoki Okumura; Naoya Hanada; Ayumi Tokunaga; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2175. doi:

ARVO Annual Meeting Abstract July 2019

Involvement of caspase 7 in the excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy

Shigehito Tonomura; Naoki Okumura; Mako Endo; Makiko Nakahara; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2176. doi:

ARVO Annual Meeting Abstract July 2019

Drug discovery for the treatment of Fuchs corneal endothelial dystrophy by cell-based drug screening system

Risako Nakagawa; Naoki Okumura; Takako Onishi; Takeshi Oshima; Emi Ueda; Kyoko Watanabe; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3877. doi:

ARVO Annual Meeting Abstract July 2019

Feasibility of mTOR inhibitor for the treatment of Fuchs endothelial corneal dystrophy

Genta Nakayama; Naoki Okumura; Takeshi Oshima; Emi Ueda; Kyoko Watanabe; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3878. doi:

Cornea February 2019

Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy

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Naoki Okumura; Ryosuke Hayashi; Masakazu Nakano; Kengo Yoshii; Kei Tashiro; Takahiko Sato; Derek J. Blake; Ross Aleff; Malinda Butz; Edward W. Highsmith; Eric D. Wieben; Michael P. Fautsch; Keith H. Baratz; Yuya Komori; Makiko Nakahara; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Noriko Koizumi
TAGS: corneal endothelium, endothelium, hereditary corneal dystrophy, rna, messenger, trinucleotide repeat expansion, dna, genome, polymerase chain reaction, cornea
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):779-786. doi: https://doi.org/10.1167/iovs.18-25760

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Influence of Fuchs endothelial corneal dystrophy on contrast sensitivity in cataract patients

Theofilos Tourtas; Victor A Augustin; Julia Weller; Friedrich E Kruse

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1311. doi:

ARVO Annual Meeting Abstract July 2018

Can we optimize the refractive target in triple Descemet membrane endothelial keratoplasty in the fellow eye after surgery in the first eye?

Victor A Augustin; Julia Weller; Friedrich E Kruse; Theofilos Tourtas

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1326. doi:

ARVO Annual Meeting Abstract July 2018

Association of rs613872 and trinucleotide repeat expansion in the TCF4 gene in Fuchs endothelial corneal dystrophy in Germany

Yuya Komori; Naoki Okumura; Ryosuke Hayashi; Masakazu Nakano; Kei Tashiro; Kengo Yoshii; Ross Aleff; Malinda Butz; Edward W. Highsmith; Eric Wieben; Michael P. Fautsch; Keith H Baratz; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1353. doi:

ARVO Annual Meeting Abstract July 2018

Establishment of a drug screening system for Fuchs endothelial corneal dystrophy

Takeshi Oshima; Naoki Okumura; Takako Onishi; Emi Ueda; Kyoko Watanabe; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1354. doi:

Cornea July 2017

Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy

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Naoki Okumura; Miu Kitahara; Hirokazu Okuda; Keisuke Hashimoto; Emi Ueda; Makiko Nakahara; Shigeru Kinoshita; Robert D. Young; Andrew J. Quantock; Theofilos Tourtas; Ursula Schlötzer-Schrehardt; Friedrich Kruse; Noriko Koizumi
TAGS: cell death, cornea, corneal endothelium, endothelium, hereditary corneal dystrophy, mitochondria, proteins, stress, unfolded protein response, cyclophosphamide, doxorubicin, prednisone, and vincristine
Invest. Ophthalmol. Vis. Sci.. 2017; 58(9):3697-3707. doi: https://doi.org/10.1167/iovs.16-21023

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Involvement of the p38 mitogen-activated protein kinase pathway in Fuchs endothelial corneal dystrophy

Takako Onishi; Naoki Okumura; Keisuke Hashimoto; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3797. doi:

ARVO Annual Meeting Abstract June 2017

Late increase in corneal thickness after DMEK: A localized phenomenon?

Anja Katharina Gruenert; Friedrich E Kruse; Dan Epstein; Theofilos Tourtas

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5691. doi:

ARVO Annual Meeting Abstract June 2017

Prediction of refractive outcomes in Descemet membrane endothelial keratoplasty combined with cataract surgery

Victor A Augustin; Julia M Weller; Friedrich E Kruse; Theofilos Tourtas

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5692. doi:

ARVO Annual Meeting Abstract June 2017

Air versus SF6 in DMEK: a fellow eye comparison of side effects

Philipp von Marchtaler; Julia M Weller; Friedrich E Kruse; Theofilos Tourtas

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5701. doi:

ARVO Annual Meeting Abstract June 2017

Structural and biochemical alterations of the posterior cornea associated with diabetes mellitus

Theofilos Tourtas; Friedrich E Kruse; Benjamin Thomas Aldrich; Julia M Weller; Jessica M Skeie; Gregory A Schmidt; Cynthia R Reed; Mark A Greiner; Ursula Schlotzer-Schrehardt

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5704. doi:

ARVO Annual Meeting Abstract June 2017

Feasibility of TGF-β inhibition for the treatment of Fuchs endothelial corneal dystrophy

Naoki Okumura; Keisuke Hashimoto; Hirokazu Okuda; Emi Ueda; Theofilos Tourtas; Ursula Schlotzer-Schrehardt; Friedrich E Kruse; Noriko Koizumi

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1434. doi:

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Effect of CTG repeat expansion in TCF4 on the pathophysiology of Fuchs endothelial corneal dystrophy

Delayed corneal clearance after uneventful Descemet Membrane endothelial keratoplasty

Supplementation of amphotericin B in Optisol-GS for Descemet membrane endothelial keratoplasty (DMEK)

Potential functional restoration of corneal endothelial cells in Fuchs corneal dystrophy by ROCK inhibitor (Ripasudil)

Involvement of a disintegrin and metalloproteinase 10 (ADAM10) in excessive extracellular matrix production in Fuchs endothelial corneal dystrophy

Involvement of caspase 7 in the excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy

Drug discovery for the treatment of Fuchs corneal endothelial dystrophy by cell-based drug screening system

Feasibility of mTOR inhibitor for the treatment of Fuchs endothelial corneal dystrophy

Effect of Trinucleotide Repeat Expansion on the Expression of TCF4 mRNA in Fuchs' Endothelial Corneal Dystrophy

Influence of Fuchs endothelial corneal dystrophy on contrast sensitivity in cataract patients

Can we optimize the refractive target in triple Descemet membrane endothelial keratoplasty in the fellow eye after surgery in the first eye?

Association of rs613872 and trinucleotide repeat expansion in the TCF4 gene in Fuchs endothelial corneal dystrophy in Germany

Establishment of a drug screening system for Fuchs endothelial corneal dystrophy

Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy

Involvement of the p38 mitogen-activated protein kinase pathway in Fuchs endothelial corneal dystrophy

Late increase in corneal thickness after DMEK: A localized phenomenon?

Prediction of refractive outcomes in Descemet membrane endothelial keratoplasty combined with cataract surgery

Air versus SF6 in DMEK: a fellow eye comparison of side effects

Structural and biochemical alterations of the posterior cornea associated with diabetes mellitus

Feasibility of TGF-β inhibition for the treatment of Fuchs endothelial corneal dystrophy

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