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Journal Articles (7)
Meeting Abstract (2)

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Investigative Ophthalmology & Visual Science (9)

Article Type

Biochemistry and Molecular Biology (5)
ARVO Annual Meeting Abstract (2)
Retinal Cell Biology (2)

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Biochemistry and Molecular Biology (6)
Eye Anatomy and Disorders (6)
Genetics (6)
Retina (6)
Immunology and Microbiology (2)
Retinal Cell Biology (2)
Visual Neuroscience (2)
Pharmacology (1)

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retina (4)
mice (3)
retinal ganglion cells (3)
calpain (2)
caspase-3 (2)
cell death (2)
disease susceptibility (2)
western blotting (2)
antioxidants (1)
apoptosis (1)

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Retinal Cell Biology July 2019

Norgestrel, a Progesterone Analogue, Promotes Significant Long-Term Neuroprotection of Cone Photoreceptors in a Mouse Model of Retinal Disease

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Sarah L. Roche; Oksana Kutsyr; Nicolás Cuenca; Thomas G. Cotter
TAGS: mice, norgestrel, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3221-3235. doi: 10.1167/iovs.19-27246

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Norgestrel-treatment does not prevent rod oxidative stress in vivo in dark-reared Pde6brd10 pups

Bruce A Berkowitz; Robert H Podolsky; Karen M Lins-Childers; Sarah Roche; Thomas G Cotter; Robin Roberts

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4868. doi:

ARVO Annual Meeting Abstract September 2016

The role of microglia-photoreceptor crosstalk in retinal cell protection

Alice Claudia Wyse Jackson; Sarah Louise Roche; Thomas G Cotter

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1192. doi:

Retinal Cell Biology September 2012

Reactive Oxygen Species Regulate Prosurvival ERK1/2 Signaling and bFGF Expression in Gliosis within the Retina

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Gillian Groeger; Francesca Doonan; Thomas G. Cotter; Maryanne Donovan
TAGS: signal transduction, western blotting, fibroblast growth factor 2, gliosis, phosphorylation, reactive oxygen species, retina, regulation
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6645-6654. doi: 10.1167/iovs.12-10525

Biochemistry and Molecular Biology October 2008

A Novel Antioxidant Function for the Tumor-Suppressor Gene p53 in the Retinal Ganglion Cell

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Jeremy C. O'Connor; Deborah M. Wallace; Colm J. O'Brien; Thomas G. Cotter
TAGS: antioxidants, catalase, disease susceptibility, genes, tumor suppressor genes, oxidation-reduction, retinal ganglion cells, enzymes, retina
Invest. Ophthalmol. Vis. Sci.. 2008; 49(10):4237-4244. doi: 10.1167/iovs.08-1963

Biochemistry and Molecular Biology December 2007

A Key Role for Calpains in Retinal Ganglion Cell Death

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Declan P. McKernan; Marc B. Guerin; Colm J. O'Brien; Thomas G. Cotter
TAGS: axotomy, calpain, cell death, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2007; 48(12):5420-5430. doi: 10.1167/iovs.07-0287

Biochemistry and Molecular Biology July 2006

Histone Deacetylase Activity Regulates Apaf-1 and Caspase 3 Expression in the Developing Mouse Retina

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Deborah M. Wallace; Maryanne Donovan; Thomas G. Cotter
TAGS: dna, histone deacetylase, mice, retina, apoptotic protease-activating factor 1, caspase-3
Invest. Ophthalmol. Vis. Sci.. 2006; 47(7):2765-2772. doi: 10.1167/iovs.05-1383

Biochemistry and Molecular Biology March 2006

Age-Dependent Susceptibility of the Retinal Ganglion Cell Layer to Cell Death

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Declan P. McKernan; Ciara Caplis; Maryanne Donovan; Colm J. O’Brien; Thomas G. Cotter
TAGS: caspases, cell death, disease susceptibility, in situ nick-end labeling, retinal ganglion cells, caspase-9, caspase-3
Invest. Ophthalmol. Vis. Sci.. 2006; 47(3):807-814. doi: 10.1167/iovs.05-0520

Biochemistry and Molecular Biology October 2005

Activation of Multiple Pathways during Photoreceptor Apoptosis in the rd Mouse

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Francesca Doonan; Maryanne Donovan; Thomas G. Cotter
TAGS: apoptosis, western blotting, calcium, calpain, cathepsin d, photoreceptors, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2005; 46(10):3530-3538. doi: 10.1167/iovs.05-0248

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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Copyright © 2015 Association for Research in Vision and Ophthalmology.

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