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ARVO Annual Meeting Abstract July 2018

Circulating O-methylascorbate is associated with population IOP variation: a metabolomics and GWAS study

Pirro G Hysi; Tim Spector; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):777. doi:

ARVO Annual Meeting Abstract July 2018

GWAS identifies 52 genomic regions associated with iris colour in a study conducted using almost 200,000 participants of European descent

Mark James Simcoe; Manfred Kayser; Tim Spector; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):781. doi:

ARVO Annual Meeting Abstract June 2013

Role of ephrin genes in cortical cataract pathogenesis

Ekaterina Yonova; Abhishek Nag; Cristina Venturini; Pirro Hysi; Katie Williams; Tim Spector; Christopher Hammond

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):899. doi:

ARVO Annual Meeting Abstract June 2013

Prevalence and Determinants of Dry Eye Disease in a British Female Cohort

Jelle Vehof; Diana Kozareva; Pirro Hysi; Samantha Fahy; Kenan Direk; Tim Spector; Christopher Hammond

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2665. doi:

Clinical and Epidemiologic Research July 2012

The Heritability of Macular Response to Supplemental Lutein and Zeaxanthin: A Classic Twin Study

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Christopher J. Hammond; S. H. Melissa Liew; Frederik J. Van Kuijk; Stephen Beatty; John M. Nolan; Tim D. Spector; Clare E. Gilbert
TAGS: carotenoids, lutein, twin studies, twins, diet
Invest. Ophthalmol. Vis. Sci.. 2012; 53(8):4963-4968. doi: https://doi.org/10.1167/iovs.12-9618

ARVO Annual Meeting Abstract March 2012

A Combined Use of Gene Expression Profiling and Genome-Wide Association Studies for the Identification of Nuclear Cataract Genetic Risk Factors

Pirro G. Hysi; Abhishek Nag; Diana Kozareva; Terri L. Young; David A. Mackey; Tim D. Spector; Christopher J. Hammond

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1546. doi:

ARVO Annual Meeting Abstract March 2012

Metabolomic Profiling of Age-Related Cataract

Christopher J. Hammond; Pirro G. Hysi; Nicole Soranzo; Christian Gieger; Timothy D. Spector

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2741. doi:

ARVO Annual Meeting Abstract April 2011

Genome-wide Association Study Of Nuclear And Cortical Cataract Identifies Potential Genes And Pathways That Alter Susceptibility To The Disease

Christopher J. Hammond; Pirro G. Hysi; Samantha J. Fahy; Tim D. Spector

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5911. doi:

ARVO Annual Meeting Abstract April 2011

Relationships Between Corneal Hysteresis And Ocular And Non-ocular Parameters In An Unselected Twin Cohort

Francis Carbonaro; Samantha Fahy; Margarida C. Lopes; Piro G. Hysi; Tim D. Spector; Christopher J. Hammond

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):6262. doi:

Clinical and Epidemiologic Research February 2011

The Relationship between Retinal Arteriolar and Venular Calibers Is Genetically Mediated, and Each Is Associated with Risk of Cardiovascular Disease

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Samantha J. Fahy; Cong Sun; Gu Zhu; Paul R. Healey; Tim D. Spector; Nicolas G. Martin; Paul Mitchell; Tien Y. Wong; David A. Mackey; Christopher J. Hammond; Toby Andrew
TAGS: cardiovascular disease risk factors, genetics, risk factors, twins, phenotype, heterogeneity of variance
Invest. Ophthalmol. Vis. Sci.. 2011; 52(2):975-981. doi: https://doi.org/10.1167/iovs.10-5927

Clinical and Epidemiologic Research November 2009

Repeated Measures of Intraocular Pressure Result in Higher Heritability and Greater Power in Genetic Linkage Studies

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Francis Carbonaro; Toby Andrew; David A. Mackey; Terri L. Young; Tim D. Spector; Christopher J. Hammond
TAGS: genetic linkage, intraocular pressure, reading (activity), eye, measurement error, twins
Invest. Ophthalmol. Vis. Sci.. 2009; 50(11):5115-5119. doi: https://doi.org/10.1167/iovs.09-3577

Clinical and Epidemiologic Research January 2009

Estimating Heritability and Shared Environmental Effects for Refractive Error in Twin and Family Studies

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Margarida C. Lopes; Toby Andrew; Francis Carbonaro; Tim D. Spector; Christopher J. Hammond
TAGS: family studies, refractive errors, twins, myopia
Invest. Ophthalmol. Vis. Sci.. 2009; 50(1):126-131. doi: https://doi.org/10.1167/iovs.08-2385

Clinical and Epidemiologic Research January 2008

The Heritability of Optic Disc Parameters: A Classic Twin Study

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Paul Healey; Francis Carbonaro; Bronwen Taylor; Tim D. Spector; Paul Mitchell; Christopher J. Hammond
TAGS: optic disk, twin studies, twins
Invest. Ophthalmol. Vis. Sci.. 2008; 49(1):77-80. doi: https://doi.org/10.1167/iovs.07-0962

Clinical and Epidemiologic Research June 2007

The Inheritance of Peripapillary Atrophy

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Paul R. Healey; Paul Mitchell; Clare E. Gilbert; Anne J. Lee; Dongliang Ge; Harold Snieder; Timothy D. Spector; Christopher J. Hammond
TAGS: atrophy, genetic inheritance, eye
Invest. Ophthalmol. Vis. Sci.. 2007; 48(6):2529-2534. doi: https://doi.org/10.1167/iovs.06-0714

Clinical and Epidemiologic Research December 2005

Heritability of Macular Pigment: A Twin Study

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Shiao Hui Melissa Liew; Clare E. Gilbert; Tim D. Spector; John Mellerio; John Marshall; Fredericus J. van Kuijk; Stephen Beatty; Fred Fitzke; Christopher J. Hammond
TAGS: optics, pigment, twin studies, twins, eye
Invest. Ophthalmol. Vis. Sci.. 2005; 46(12):4430-4436. doi: https://doi.org/10.1167/iovs.05-0519

Glaucoma October 2005

Central Corneal Thickness Is Highly Heritable: The Twin Eye Studies

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Tze’Yo Toh; S. H. Melissa Liew; Jane R. MacKinnon; Alex W. Hewitt; Johan L. Poulsen; Tim D. Spector; Clare E. Gilbert; Jamie E Craig; Christopher J. Hammond; David A. Mackey
TAGS: cornea, eye, twins
Invest. Ophthalmol. Vis. Sci.. 2005; 46(10):3718-3722. doi: https://doi.org/10.1167/iovs.04-1497

Clinical and Epidemiologic Research May 2001

Genes and Environment in Refractive Error: The Twin Eye Study

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Christopher J. Hammond; Harold Snieder; Clare E. Gilbert; Tim D. Spector
TAGS: astigmatism, eye, genes, refractive errors, twins, myopia, genetics, twin studies
Invest. Ophthalmol. Vis. Sci.. 2001; 42(6):1232-1236. doi:

Clinical and Epidemiologic Research March 2001

The Heritability of Age-Related Cortical Cataract: The Twin Eye Study

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Christopher J. Hammond; Donald D. Duncan; Harold Snieder; Marlies de Lange; Sheila K. West; Tim D. Spector; Clare E. Gilbert
TAGS: cortical cataract, eye, twins
Invest. Ophthalmol. Vis. Sci.. 2001; 42(3):601-605. doi:

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Circulating O-methylascorbate is associated with population IOP variation: a metabolomics and GWAS study

GWAS identifies 52 genomic regions associated with iris colour in a study conducted using almost 200,000 participants of European descent

Role of ephrin genes in cortical cataract pathogenesis

Prevalence and Determinants of Dry Eye Disease in a British Female Cohort

The Heritability of Macular Response to Supplemental Lutein and Zeaxanthin: A Classic Twin Study

A Combined Use of Gene Expression Profiling and Genome-Wide Association Studies for the Identification of Nuclear Cataract Genetic Risk Factors

Metabolomic Profiling of Age-Related Cataract

Genome-wide Association Study Of Nuclear And Cortical Cataract Identifies Potential Genes And Pathways That Alter Susceptibility To The Disease

Relationships Between Corneal Hysteresis And Ocular And Non-ocular Parameters In An Unselected Twin Cohort

The Relationship between Retinal Arteriolar and Venular Calibers Is Genetically Mediated, and Each Is Associated with Risk of Cardiovascular Disease

Repeated Measures of Intraocular Pressure Result in Higher Heritability and Greater Power in Genetic Linkage Studies

Estimating Heritability and Shared Environmental Effects for Refractive Error in Twin and Family Studies

The Heritability of Optic Disc Parameters: A Classic Twin Study

The Inheritance of Peripapillary Atrophy

Heritability of Macular Pigment: A Twin Study

Central Corneal Thickness Is Highly Heritable: The Twin Eye Studies

Genes and Environment in Refractive Error: The Twin Eye Study

The Heritability of Age-Related Cortical Cataract: The Twin Eye Study

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