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Meeting Abstract (10)
Journal Articles (6)

Journal

Investigative Ophthalmology & Visual Science (16)

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ARVO Annual Meeting Abstract (10)
Retina (4)
Retinal Cell Biology (2)

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Eye Anatomy and Disorders (4)
Genetics (4)
Retina (4)
Immunology and Microbiology (3)
Biochemistry and Molecular Biology (2)
Retinal Cell Biology (2)
Clinical and Epidemiologic Research (1)

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low-density lipoproteins (6)
suidae (4)
apoptosis (2)
diabetic retinopathy (2)
berberine (1)
cell death (1)
cohort studies (1)
cytotoxicity (1)
dcct trial (1)
edic trial (1)

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ARVO Annual Meeting Abstract July 2019

Mitochondrial quality control is dysregulated in diabetic retinopathy

Jose Manuel Romero del Hombre; Lauren Cairns; Timothy J Lyons; Paul Moynagh; Tim M Curtis; Heping Xu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6430. doi:

ARVO Annual Meeting Abstract June 2017

Analysis of Sphingolipid Composition of Human Vitreous from Control and Diabetic Individuals

Lynda A Wilmott; Megan Stiles; Timothy Lyons; Nawajes A Mandal

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2522. doi:

Retinal Cell Biology June 2016

Beneficial Effects of Berberine on Oxidized LDL-Induced Cytotoxicity to Human Retinal Müller Cells

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Dongxu Fu; Jeremy Y. Yu; Anna R. Connell; Shihe Yang; Michelle B. Hookham; Rebecca McLeese; Timothy J. Lyons
TAGS: berberine, low-density lipoproteins, suidae, cytotoxicity
Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3369-3379. doi: https://doi.org/10.1167/iovs.16-19291

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2013

Autophagy in Modified LDL-induced Pericyte Loss in Diabetic Retinopathy

Dongxu Fu; Shihe Yang; Mingyuan Wu; Mei Du; Junping Chen; Kenneth Wilson; Timothy Lyons

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):272. doi:

Retina July 2012

Oxidative and Endoplasmic Reticulum Stresses Mediate Apoptosis Induced by Modified LDL in Human Retinal Müller Cells

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Mingyuan Wu; Shihe Yang; Michael H. Elliott; Dongxu Fu; Kenneth Wilson; Jing Zhang; Mei Du; Junping Chen; Timothy Lyons
TAGS: apoptosis, low-density lipoproteins, suidae, stress, cell death
Invest. Ophthalmol. Vis. Sci.. 2012; 53(8):4595-4604. doi: https://doi.org/10.1167/iovs.12-9910

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Berberine Acts As A Novel Autophagy Blocker To Protect Human müLler Cell From 4-hne Induced Cell Death

SHIHE YANG; Mingyuan Wu; Dongxu Fu; Junping Chen; Jing zhang; Kenneth Wilson; Michael Elliot; Mei Du; Timothy Lyons

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2019. doi:

ARVO Annual Meeting Abstract March 2012

Autophagy in Modified LDL-induced Pericyte Loss in Diabetic Retinopathy

Dongxu Fu; Jing Zhang; Shihe Yang; Mei Du; Mingyuan Wu; Kenneth Wilson; Junping Chen; Timothy Lyons

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2437. doi:

ARVO Annual Meeting Abstract March 2012

Effects Of Fenofibrate On Modified-ldl-induced Retinal Cell Injury And Retinopathy In Stz-diabetic Mice

Jing Zhang; Shihe Yang; Dongxu Fu; Mingyuan Wu; Mei Du; Kenneth Wilson; Timothy Lyons

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3283. doi:

ARVO Annual Meeting Abstract April 2011

Mechanisms for the Therapeutic Effect of Fenofibrate on Diabetic Retinopathy in Type 1 Diabetes Models

Ying Chen; Yang Hu; Robert Mott; Scott Mitchell; Mingkai Lin; Kevin Zhou; Alicia Jenkins; Anthony Keech; Timothy Lyons; Jian-xing Ma

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2100. doi:

ARVO Annual Meeting Abstract April 2011

Acceleration Of Retinopathy By Intravitreal Injection Of Modified Low Density Lipoproteins In-STZ Diabetic Mice

Jing Zhang; Mingyuan Wu; Dongxu Fu; Shihe Yang; Michael H. Elliott; Mei Du; Kenneth W. Wilson; Timothy J. Lyons

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5974. doi:

ARVO Annual Meeting Abstract April 2011

High Oxidized Glycated Low Density Lipoprotein Induces Apoptosis in Human Retinal Muller Cells via Activation of Oxidative Stress and Endoplasmic Reticulum Stress

Mingyuan Wu; Shihe Yang; Michael H. Elliott; Dongxu Fu; Kenneth Wilson; Jing Zhang; Mei Du; Junping Chen; Timothy J. Lyons

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):510. doi:

ARVO Annual Meeting Abstract April 2011

Modified LDL Increases Endoplasmic Reticulum Stress And Retinal Injury In Diabetes Mellitus

Dongxu Fu; Mingyuan Wu; Jing Zhang; Shihe Yang; Mei Du; Kenneth Wilson; Timothy J. Lyons

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3549. doi:

Retina June 2008

Intraretinal Leakage and Oxidation of LDL in Diabetic Retinopathy

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Mingyuan Wu; Ying Chen; Kenneth Wilson; Alin Chirindel; Michael A. Ihnat; Yongxin Yu; Michael E. Boulton; Luke I. Szweda; Jian-Xing Ma; Timothy J. Lyons
TAGS: low-density lipoproteins, diabetic retinopathy, apoptosis, oxidation, suidae
Invest. Ophthalmol. Vis. Sci.. 2008; 49(6):2679-2685. doi: https://doi.org/10.1167/iovs.07-1440

Retinal Cell Biology August 2005

Effects of Oxidized and Glycated LDL on Gene Expression in Human Retinal Capillary Pericytes

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Weiwei Song; Jeremy L. Barth; Yongxin Yu; Kangmo Lu; Azar Dashti; Yan Huang; Cynthia K. Gittinger; W. Scott Argraves; Timothy J. Lyons
TAGS: genes, low-density lipoproteins, pericytes, suidae, gene expression
Invest. Ophthalmol. Vis. Sci.. 2005; 46(8):2974-2982. doi: https://doi.org/10.1167/iovs.04-1505

Includes: Supplemental Content

Retina March 2004

Diabetic Retinopathy and Serum Lipoprotein Subclasses in the DCCT/EDIC Cohort

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Timothy J. Lyons; Alicia J. Jenkins; Deyi Zheng; Daniel T. Lackland; Daniel McGee; W. Timothy Garvey; Richard L. Klein
TAGS: cohort studies, dcct trial, diabetic retinopathy, edic trial, lipoproteins, low-density lipoproteins, retinal diseases, high density lipoproteins, lipoproteins, vldl
Invest. Ophthalmol. Vis. Sci.. 2004; 45(3):910-918. doi: https://doi.org/10.1167/iovs.02-0648

Retina April 2000

Aminoguanidine and the Effects of Modified LDL on Cultured Retinal Capillary Cells

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Timothy J. Lyons; Wei Li; Barbara Wojciechowski; Mary C. Wells–Knecht; Kevin J. Wells–Knecht; Alicia J. Jenkins
TAGS: low-density lipoproteins, pimagedine
Invest. Ophthalmol. Vis. Sci.. 2000; 41(5):1176-1180. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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