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Retina February 2025

Relationship of OCT-Based Diabetic Retinal Neurodegeneration to the Development and Progression of Diabetic Retinopathy: A Cohort Study

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Ziqi Tang; Dawei Yang; Truong X. Nguyen; Shuyi Zhang; Danqi Fang; Victor T. T. Chan; Clement C. Tham; Elliott H. Sohn; Ken K. Tsang; Cherie Y. K. Wong; Vivian W. K. Hui; Amy H. Y. Yu; Julia T. W. Lam; Carmen K. M. Chan; Timothy Y. Y. Lai; Simon K. H. Szeto; Carol Y. Cheung
TAGS: cohort studies, diabetes mellitus, diabetic retinopathy, dorsal raphe nucleus, nerve degeneration, eye, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):32. https://doi.org/10.1167/iovs.66.2.32

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Applying Novel AI-Based Generalizability Technology and Establishing an Uncertainty Range for Diabetic Macular Edema Detection from 3D Optical Coherence Tomography Scans: A Prospective Validation Analysis in a Lower-Middle-Income Country

Truong Xuan Nguyen; Meirui Jiang; Dawei Yang; Timothy Y Y Lai; Simon Szeto; Mary Ho; Theodore Leng; Gavin Tan; Triet Thanh Nguyen; Qi Dou; Carol Cheung

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3729.

ARVO Annual Meeting Abstract June 2024

Greater reduction in pigment epithelial detachment size in TENAYA/LUCERNE with faricimab 6.0 mg vs aflibercept 2.0 mg during head-to-head dosing in patients with nAMD

Nikolas London; Arshad M. Khanani; Timothy Y Y Lai; Jennifer I Lim; Aachal Kotecha; Philippe Margaron; Shriji Patel; Audrey Souverain; Jeffrey R Willis; Ming Yang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5690.

ARVO Annual Meeting Abstract June 2022

Association of fundus autofluorescence changes and pachydrusen in central serous chorioretinopathy and polypoidal choroidal vasculopathy

Timothy Y Y Lai; Ziqi Tang; Adrian C W Lai; Ricky Y K Lai; Carol Y. Cheung

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3753 – F0174.

ARVO Annual Meeting Abstract June 2021

Association between retinal thickness variability and visual acuity outcome during anti-vascular endothelial therapy for neovascular age-related macular degeneration

Timothy Y Y Lai; Ricky Y K Lai

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):433.

Special Issue May 2021

IMI Pathologic Myopia

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Kyoko Ohno-Matsui; Pei-Chang Wu; Kenji Yamashiro; Kritchai Vutipongsatorn; Yuxin Fang; Chui Ming Gemmy Cheung; Timothy Y. Y. Lai; Yasushi Ikuno; Salomon Yves Cohen; Alain Gaudric; Jost B. Jonas
TAGS: eye, macular disorders, myopia, myopic macular degeneration, staphyloma, macula lutea
Invest. Ophthalmol. Vis. Sci.. 2021; 62(5):5. https://doi.org/10.1167/iovs.62.5.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Dual inhibition of Ang-2 and VEGF-A with faricimab in diabetic macular edema: Evidence for increased durability from the BOULEVARD phase 2 trial

Timothy Y Y Lai; Jayashree Sahni; Karen Basu; Stefan Scheidl; Jeffrey Ryuta Willis; Aaron Osborne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3860.

ARVO Annual Meeting Abstract June 2017

Anatomical outcomes of ranibizumab 0.5 mg combined with verteporfin photodynamic therapy vs ranibizumab monotherapy in patients with polypoidal choroidal vasculopathy: 12-month results from the EVEREST II study

Timothy Y Y Lai; Chrystel Feller; Philippe Margaron; Colin S Tan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):408.

Genetics February 2017

Identification of ANGPT2 as a New Gene for Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in the Chinese and Japanese Populations

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Li Ma; Marten E. Brelen; Motokazu Tsujikawa; Haoyu Chen; Wai Kit Chu; Timothy Y. Y. Lai; Danny S. C. Ng; Kaori Sayanagi; Chicako Hara; Noriyasu Hashida; Vesta C. K. Chan; Pancy O. S. Tam; Alvin L. Young; Weiqi Chen; Kohji Nishida; Chi Pui Pang; Li Jia Chen
TAGS: chinese (other dialects), chinese people, cohort studies, exudative age-related macular degeneration, genes, japanese, single nucleotide polymorphism, vascular diseases, hong kong
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):1076-1083. https://doi.org/10.1167/iovs.16-20575

Includes: Supplemental Content

Retina February 2017

Classification of Exudative Age-Related Macular Degeneration With Pachyvessels on En Face Swept-Source Optical Coherence Tomography

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Danny Siu-Chun Ng; Malini Bakthavatsalam; Frank Hiu-Ping Lai; Carol Yim-Lui Cheung; Gemmy Chu-Ming Cheung; Fang Yao Tang; Chi Wai Tsang; Timothy Yuk-Yau Lai; Tien Yin Wong; Mårten Erik Brelén
TAGS: cortical blindness, exudative age-related macular degeneration, eye, face, optical coherence tomography, macular disorders
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):1054-1062. https://doi.org/10.1167/iovs.16-20519

Genetics October 2016

Association of ABCG1 With Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Chinese and Japanese

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Li Ma; Ke Liu; Motokazu Tsujikawa; Haoyu Chen; Marten E. Brelen; Vesta C. K. Chan; Timothy Y. Y. Lai; Kaori Sayanagi; Chicako Hara; Noriyasu Hashida; Pancy O. S. Tam; Alvin L. Young; Weiqi Chen; Kohji Nishida; Chi Pui Pang; Li Jia Chen
TAGS: chinese (other dialects), chinese people, cohort studies, exudative age-related macular degeneration, japanese, single nucleotide polymorphism, vascular diseases, hong kong, genes
Invest. Ophthalmol. Vis. Sci.. 2016; 57(13):5758-5763. https://doi.org/10.1167/iovs.16-20175

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Optical coherence tomography angiography study of submacular hemorrhage and choroidal neovascularization secondary to pathological myopia

Frank Lai; Danny Ng; Marten Brelen; Carol Yim-lui Cheung; Timothy Y Y Lai; Fiona Luk; Alvin Young

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2165.

ARVO Annual Meeting Abstract September 2016

Efficacy and safety of ranibizumab 0.5 mg (RBZ) in patients with visual impairment due to choroidal neovascularization (CNV) associated with rare diseases: 6-month results from MINERVA

Timothy Y Y Lai; Sabine Desset-Brethes; Vladimir Bezlyak; Melissa Liew

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12)

Retina April 2016

Identification of PGF as a New Gene for Neovascular Age-Related Macular Degeneration in a Chinese Population

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Li Jia Chen; Li Ma; Wai Kit Chu; Timothy Y. Y. Lai; Haoyu Chen; Mårten E. Brelén; Shi Song Rong; Alvin L. Young; Pancy O. S. Tam; Mingzhi Zhang; Chi Pui Pang
TAGS: chinese people, exudative age-related macular degeneration, genes, hong kong, single nucleotide polymorphism, cohort studies, haplotypes, disease susceptibility
Invest. Ophthalmol. Vis. Sci.. 2016; 57(4):1714-1720. https://doi.org/10.1167/iovs.IOVS-15-18677

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

ABCG1 as a new susceptibility gene for age-related macular degeneration and polypoidal choroidal vasculopathy

Li Ma; Ke Liu; Timothy Y Y Lai; Pancy O.S. Tam; Chi Pui Pang; Li Jia Chen

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):781.

ARVO Annual Meeting Abstract June 2015

Association of the vascular endothelial growth factor genes with age-related macular degeneration and polypoidal choroidal vasculopathy

Li Jia Chen; Li Ma; Timothy Y Y Lai; Marten Erik Brelen; Pancy O.S. Tam; Chi Pui Pang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):786.

ARVO Annual Meeting Abstract June 2015

Correlation of aqueous cytokines with OCT appearance in patients with diabetic macular oedema.

Marten Erik Brelen; Shaheeda Mohamed; Carmen Chan; Fiona Luk; PuiPui Yip; Chi-Wai Tsang; Timothy Y Y Lai; Yolanda Yip; Alvin Young; Chi Pui Pang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4679.

Genetics September 2012

Association of Genetic Variants on 8p21 and 4q12 with Age-Related Macular Degeneration in Asian Populations

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Isao Nakata; Kenji Yamashiro; Yumiko Akagi-Kurashige; Masahiro Miyake; Kyoko Kumagai; Akitaka Tsujikawa; Ke Liu; Li Jia Chen; David T. L. Liu; Timothy Y. Y. Lai; Yoichi Sakurada; Seigo Yoneyama; Ching-Yu Cheng; Peter Cackett; Ian Y. Yeo; Wan Ting Tay; Belinda K. Cornes; Eranga N. Vithana; Tin Aung; Keitaro Matsuo; Fumihiko Matsuda; Tien-Yin Wong; Hiroyuki Iijima; Chi Pui Pang; Nagahisa Yoshimura
TAGS: age-related macular degeneration, asian, cohort studies, exudative age-related macular degeneration, genetics, japanese, chinese (other dialects), choroidal neovascularization, chinese people, meta-analysis
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6576-6581. https://doi.org/10.1167/iovs.12-10219

Genetics July 2012

Association of C2 and CFB Polymorphisms with Anterior Uveitis

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Ming-ming Yang; Timothy Y. Y. Lai; Pancy O. S. Tam; Sylvia W. Y. Chiang; Tsz Kin Ng; Ke Liu; Chi Pui Pang
TAGS: polymorphism, single nucleotide polymorphism, uveitis, anterior, hla-b27 antigen, haplotypes, alleles
Invest. Ophthalmol. Vis. Sci.. 2012; 53(8):4969-4974. https://doi.org/10.1167/iovs.12-9478

Genetics May 2012

Differentiation of Exudative Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in the ARMS2 / HTRA1 Locus

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Xiao Ying Liang; Timothy Y. Y. Lai; David T. L. Liu; Alex H. Fan; Li Jia Chen; Pancy O. S. Tam; Sylvia W. Y. Chiang; Tsz Kin Ng; Dennis S. C. Lam; Chi Pui Pang
TAGS: exudative age-related macular degeneration, htra1 gene, vascular diseases, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2012; 53(6):3175-3182. https://doi.org/10.1167/iovs.11-8135

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Relationship of OCT-Based Diabetic Retinal Neurodegeneration to the Development and Progression of Diabetic Retinopathy: A Cohort Study

Applying Novel AI-Based Generalizability Technology and Establishing an Uncertainty Range for Diabetic Macular Edema Detection from 3D Optical Coherence Tomography Scans: A Prospective Validation Analysis in a Lower-Middle-Income Country

Greater reduction in pigment epithelial detachment size in TENAYA/LUCERNE with faricimab 6.0 mg vs aflibercept 2.0 mg during head-to-head dosing in patients with nAMD

Association of fundus autofluorescence changes and pachydrusen in central serous chorioretinopathy and polypoidal choroidal vasculopathy

Association between retinal thickness variability and visual acuity outcome during anti-vascular endothelial therapy for neovascular age-related macular degeneration

IMI Pathologic Myopia

Dual inhibition of Ang-2 and VEGF-A with faricimab in diabetic macular edema: Evidence for increased durability from the BOULEVARD phase 2 trial

Anatomical outcomes of ranibizumab 0.5 mg combined with verteporfin photodynamic therapy vs ranibizumab monotherapy in patients with polypoidal choroidal vasculopathy: 12-month results from the EVEREST II study

Identification of ANGPT2 as a New Gene for Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in the Chinese and Japanese Populations

Classification of Exudative Age-Related Macular Degeneration With Pachyvessels on En Face Swept-Source Optical Coherence Tomography

Association of ABCG1 With Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Chinese and Japanese

Optical coherence tomography angiography study of submacular hemorrhage and choroidal neovascularization secondary to pathological myopia

Efficacy and safety of ranibizumab 0.5 mg (RBZ) in patients with visual impairment due to choroidal neovascularization (CNV) associated with rare diseases: 6-month results from MINERVA

Identification of PGF as a New Gene for Neovascular Age-Related Macular Degeneration in a Chinese Population

ABCG1 as a new susceptibility gene for age-related macular degeneration and polypoidal choroidal vasculopathy

Association of the vascular endothelial growth factor genes with age-related macular degeneration and polypoidal choroidal vasculopathy

Correlation of aqueous cytokines with OCT appearance in patients with diabetic macular oedema.

Association of Genetic Variants on 8p21 and 4q12 with Age-Related Macular Degeneration in Asian Populations

Association of C2 and CFB Polymorphisms with Anterior Uveitis

Differentiation of Exudative Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in the ARMS2 / HTRA1 Locus

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