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ARVO Annual Meeting Abstract June 2020

Detailed Phenotype of Autoimmune Retinopathies with Electroretinography, Multimodal-Imaging and Visual Psychophysics

Yafeng Li; Leona Serrano; Erin O'Neil; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2099. doi:

ARVO Annual Meeting Abstract June 2020

Natural History of Rod and Cone Photoreceptor Dysfunction in Choroideremia

Kurt Scavelli; Erin O'Neil; Leona Serrano; Denise J. Pearson; Jessica Ijams Wolfing Morgan; Albert Maguire; Jean Bennett; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3027. doi:

ARVO Annual Meeting Abstract June 2020

Treatment Potential for LCA5 -associated Leber Congenital Amaurosis

Katherine E. Uyhazi; Puya Aravand; Brent A. Bell; Zhangyong Wei; Lanfranco Leo; Leona Serrano; Denise J. Pearson; Ivan Shpylchak; Jennifer Pham; Vidyullatha Vasireddy; Jean Bennett; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4500. doi:

Retina May 2020

Treatment Potential for LCA5 -Associated Leber Congenital Amaurosis

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Katherine E. Uyhazi; Puya Aravand; Brent A. Bell; Zhangyong Wei; Lanfranco Leo; Leona W. Serrano; Denise J. Pearson; Ivan Shpylchak; Jennifer Pham; Vidyullatha Vasireddy; Jean Bennett; Tomas S. Aleman
TAGS: electroretinography, leber's amaurosis, mice, photoreceptors, tissue degeneration, eye, injections, retina, spectral domain-optical coherence tomography, excipients
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):30. doi: https://doi.org/10.1167/iovs.61.5.30

Includes: Supplemental Content

Perspective February 2020

Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations

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Ian M. MacDonald; Christopher Moen; Jacque L. Duncan; Stephen H. Tsang; Jasmina Cehajic-Kapetanovic; Tomas S. Aleman
TAGS: choroideremia, gene therapy, retinal degeneration, spatial vectors
Trans. Vis. Sci. Tech.. 2020; 9(3):17. doi: https://doi.org/10.1167/tvst.9.3.17

ARVO Annual Meeting Abstract July 2019

Outer Retina Thinning Distinguishes Frontotemporal Degeneration from Alzheimer’s Disease

Benjamin J Kim; Murray Grossman; Adrienne Saludades; Delu Song; Joshua L Dunaief; Brendan McGeehan; Gui-Shuang Ying; Tomas S Aleman; David Irwin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2296. doi:

ARVO Annual Meeting Abstract July 2019

Cone Outer Segment Reflectance Entropy in Choroideremia

Andrew M. Huang; Robert F Cooper; Grace Vergilio; Jean Bennett; Albert M. Maguire; Tomas S Aleman; Jessica Ijams Wolfing Morgan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1030. doi:

ARVO Annual Meeting Abstract July 2019

Automated cone identification in adaptive optics retinal images of Choroideremia using a convolutional neural network

Jessica Ijams Wolfing Morgan; Min Chen; Grace Vergilio; Andrew M. Huang; Jean Bennett; Albert M. Maguire; Tomas S Aleman; Robert F Cooper

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1431. doi:

ARVO Annual Meeting Abstract July 2019

Structural Correlates of Short-wavelength and Normalized Near-infrared Fundus Autofluorescence Imaging in Choroideremia.

Drew Scoles; Kurt Scavelli; Leona Serrano; Katherine E Uyhazi; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1864. doi:

ARVO Annual Meeting Abstract July 2019

Structural and Functional Abnormalities in Leber Congenital Amaurosis Caused by Mutations in RDH12: A Short-Term Longitudinal Study

Katherine E. Uyhazi; Leona Serrano; Grace Vergilio; Denise J Pearson; Albert M. Maguire; Jean Bennett; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4509. doi:

ARVO Annual Meeting Abstract July 2019

Structural Markers Predictive of Visual Acuity in Choroideremia

Kurt Scavelli; Drew Scoles; Leona Serrano; Katherine E. Uyhazi; Jessica Ijams Wolfing Morgan; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4523. doi:

ARVO Annual Meeting Abstract July 2019

AAV2- hCHM Subretinal Delivery to the Macula in Choroideremia: 2 year Results of an Ongoing Phase I/II Gene Therapy Trial

Tomas S Aleman; Rachel M Huckfeldt; Leona Serrano; Grace Vergilio; Denise J Pearson; Katherine E. Uyhazi; Sarah McCague; Kathleen Marshall; Daniel C Chung; Emily Liu; Eric A Pierce; Jessica Ijams Wolfing Morgan; Jean Bennett; Dean Eliott; Jason Comander; Albert M. Maguire

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5173. doi:

ARVO Annual Meeting Abstract July 2019

Variants in myelin regulatory factor ( MYRF) cause autosomal dominant nanophthalmos.

Lev Prasov; Sarah J Garnai; Michelle Brinkmeier; Ben Emery; Tomas S Aleman; Louise C Pyle; Biliana O Veleva-Rotse; Robert Sisk; Sayoko Eileen Moroi; Steven M Archer; Laurel Wiinikka-Buesser; Frank W Rozsa; Gregory L Skuta; Sally Camper; Julia Richards

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5420. doi:

ARVO Annual Meeting Abstract July 2019

Subfoveal gene augmentation therapy for choroideremia: One-year results from a Phase I/II trial of AAV2-hCHM

Rachel M Huckfeldt; Tomas S Aleman; Tu Doan; Xiao-Hong Wen; Carol Weigel-DiFranco; Daniel C Chung; Emily Liu; Eric A Pierce; Jean Bennett; Albert M. Maguire; Dean Eliott; Jason Comander

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6401. doi:

Retina October 2018

RDH12 Mutations Cause a Severe Retinal Degeneration With Relatively Spared Rod Function

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Tomas S. Aleman; Katherine E. Uyhazi; Leona W. Serrano; Vidyullatha Vasireddy; Scott J. Bowman; Michael J. Ammar; Denise J. Pearson; Albert M. Maguire; Jean Bennett
TAGS: mutation, retina, retinal degeneration, rod photoreceptors, spectral domain-optical coherence tomography, pathophysiology
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5225-5236. doi: https://doi.org/10.1167/iovs.18-24708

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Early Structural and Functional Abnormalities in Leber Congenital Amaurosis Caused by Mutations in RDH12

Tomas S Aleman; Katherine E Uyhazi; Leona Serrano; Scott J Bowman; Denise J Pearson; Albert M Maguire; Jean Bennett

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):46. doi:

ARVO Annual Meeting Abstract July 2018

Cellular-scale assessment of visual function in Choroideremia

Jessica Ijams Wolfing Morgan; William Scott Tuten; Robert F Cooper; Grace K. Han; Gloria Young; Jean Bennett; Albert M Maguire; Tomas S Aleman; David H Brainard

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1151. doi:

ARVO Annual Meeting Abstract July 2018

Safety of the Subretinal Delivery of RGX-314 AAV8-anti-VEGF Fab Gene Therapy in NHP: Retinal Structure Over One Year

Michael J. Ammar; Elaine J Zhou; Jessica Ijams Wolfing Morgan; Katherine E Uyhazi; Arkady Lyubarsky; Erik Wielechowski; Gui-Shuang Ying; Erin Bote; Leah Makaron; Stephen Yoo; James Wilson; Jean Bennett; Albert M Maguire; Anna Tretiakova; Tomas S Aleman

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1422. doi:

ARVO Annual Meeting Abstract July 2018

Safety of subretinal delivery of RGX-314 (AAV8-anti-VEGF Fab) in the non-human primate as assessed by full-field ERG

Arkady Lyubarsky; Erik Wielechowski; Tomas S Aleman; Albert M Maguire; Gui-Shuang Ying; Erin Bote; Leah Makaron; Jessica Ijams Wolfing Morgan; Anna Tretiakova; James Wilson; Jean Bennett

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4546. doi:

Visual Neuroscience July 2018

Comparing Clinical Perimetry and Population Receptive Field Measures in Patients with Choroideremia

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Edward H. Silson; Tomas S. Aleman; Aimee Willett; Leona W. Serrano; Denise J. Pearson; Andreas M. Rauschecker; Albert M. Maguire; Chris I. Baker; Jean Bennett; Manzar Ashtari
TAGS: prolactin-releasing hormone, visual fields, choroideremia, perimetry
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3249-3258. doi: https://doi.org/10.1167/iovs.18-23929

Includes: Supplemental Content

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Detailed Phenotype of Autoimmune Retinopathies with Electroretinography, Multimodal-Imaging and Visual Psychophysics

Natural History of Rod and Cone Photoreceptor Dysfunction in Choroideremia

Treatment Potential for LCA5 -associated Leber Congenital Amaurosis

Treatment Potential for LCA5 -Associated Leber Congenital Amaurosis

Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations

Outer Retina Thinning Distinguishes Frontotemporal Degeneration from Alzheimer’s Disease

Cone Outer Segment Reflectance Entropy in Choroideremia

Automated cone identification in adaptive optics retinal images of Choroideremia using a convolutional neural network

Structural Correlates of Short-wavelength and Normalized Near-infrared Fundus Autofluorescence Imaging in Choroideremia.

Structural and Functional Abnormalities in Leber Congenital Amaurosis Caused by Mutations in RDH12: A Short-Term Longitudinal Study

Structural Markers Predictive of Visual Acuity in Choroideremia

AAV2- hCHM Subretinal Delivery to the Macula in Choroideremia: 2 year Results of an Ongoing Phase I/II Gene Therapy Trial

Variants in myelin regulatory factor ( MYRF) cause autosomal dominant nanophthalmos.

Subfoveal gene augmentation therapy for choroideremia: One-year results from a Phase I/II trial of AAV2-hCHM

RDH12 Mutations Cause a Severe Retinal Degeneration With Relatively Spared Rod Function

Early Structural and Functional Abnormalities in Leber Congenital Amaurosis Caused by Mutations in RDH12

Cellular-scale assessment of visual function in Choroideremia

Safety of the Subretinal Delivery of RGX-314 AAV8-anti-VEGF Fab Gene Therapy in NHP: Retinal Structure Over One Year

Safety of subretinal delivery of RGX-314 (AAV8-anti-VEGF Fab) in the non-human primate as assessed by full-field ERG

Comparing Clinical Perimetry and Population Receptive Field Measures in Patients with Choroideremia

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