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Meeting Abstract (3)
Journal Articles (2)

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Investigative Ophthalmology & Visual Science (5)

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ARVO Annual Meeting Abstract (3)
Glaucoma (2)

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Glaucoma (2)
Pharmacology (2)
Eye Anatomy and Disorders (1)
Visual Neuroscience (1)

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agonists (1)
antihypertensive agents (1)
intraocular pressure (1)
mitogen-activated protein kinase p38 (1)
neuroprotective effect (1)
pharmacology (1)
prostaglandins (1)
retinal ganglion cells (1)
tranylcypromine (1)

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Glaucoma January 2018

Pharmacologic Characterization of Omidenepag Isopropyl, a Novel Selective EP2 Receptor Agonist, as an Ocular Hypotensive Agent

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Tomoko Kirihara; Takazumi Taniguchi; Kenzo Yamamura; Ryo Iwamura; Kenji Yoneda; Noriko Odani-Kawabata; Atsushi Shimazaki; Takeshi Matsugi; Naveed Shams; Jin-Zhong Zhang
TAGS: agonists, antihypertensive agents, intraocular pressure, pharmacology, prostaglandins
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):145-153. doi: https://doi.org/10.1167/iovs.17-22745

ARVO Annual Meeting Abstract June 2017

Omidenepag isopropyl, a selective EP2 agonist, shows additive intraocular pressure (IOP)-lowering effects when used concomitantly with existing anti-glaucoma drugs in animal models

Takazumi Taniguchi; Tomoko Kirihara; Miki Takahashi; Ryo Iwamura; Kenji Yoneda; Noriko Odani; Atsushi Shimazaki; Masaki Ichikawa; Jin-Zhong Zhang

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2105. doi:

Glaucoma November 2016

Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity

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Takayuki Tsutsumi; Keiichiro Iwao; Hideki Hayashi; Tomoko Kirihara; Takahiro Kawaji; Toshihiro Inoue; Shinjiro Hino; Mitsuyoshi Nakao; Hidenobu Tanihara
TAGS: neuroprotective effect, tranylcypromine, mitogen-activated protein kinase p38, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6461-6473. doi: https://doi.org/10.1167/iovs.16-19494

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

Advantages of tafluprost/timolol fixed-dose combination in the view points of efficacy duration and corneal safety

Takahiro Akaishi; Tomoko Kirihara; Naoko Yamashita; Kenji Ueda; Atsushi Shimazaki; Hidetoshi Mano; Kouichi Kawazu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5697. doi:

ARVO Annual Meeting Abstract June 2015

DE-117, a selective EP2 agonist, lowered intraocular pressure in animal models

Tomoko Kirihara; Ryo Iwamura; Kenji Yoneda; Noriko Kawabata-Odani; Atsushi Shimazaki; Kouichi Kawazu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5709. doi:

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Online ISSN: 1552-5783

Investigative Ophthalmology & Visual Science
Journal of Vision
Translational Vision Science & Technology

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Copyright © 2015 Association for Research in Vision and Ophthalmology.

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