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Glaucoma June 2019

Sectoral Differences in the Association of Optic Nerve Head Blood Flow and Glaucomatous Visual Field Defect Severity and Progression

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Naoki Kiyota; Yukihiro Shiga; Masayuki Yasuda; Naoko Aizawa; Kazuko Omodaka; Satoru Tsuda; Hiroshi Kunikata; Toru Nakazawa
TAGS: glaucomatous visual field defect, optic disk, vascular flow, body tissue
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2650-2658. doi: 10.1167/iovs.19-27230

Includes: Supplemental Content

Genetics March 2019

Macular Dystrophy and Cone-Rod Dystrophy Caused by Mutations in the RP1 Gene: Extending the RP1 Disease Spectrum

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Sanne K. Verbakel; Ramon A. C. van Huet; Anneke I. den Hollander; Maartje J. Geerlings; Eveline Kersten; B. Jeroen Klevering; Caroline C. W. Klaver; Astrid S. Plomp; Nieneke L. Wesseling; Arthur A. B. Bergen; Konstantinos Nikopoulos; Carlo Rivolta; Yasuhiro Ikeda; Koh-Hei Sonoda; Yuko Wada; Camiel J. F. Boon; Toru Nakazawa; Carel B. Hoyng; Koji M. Nishiguchi
TAGS: phenotype, mutation, family, genes, retinitis pigmentosa, genetics, age-related macular degeneration, macular dystrophy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1192-1203. doi: 10.1167/iovs.18-26084

Includes: Supplemental Content

Retinal Cell Biology August 2018

Ecel1 Knockdown With an AAV2-Mediated CRISPR/Cas9 System Promotes Optic Nerve Damage-Induced RGC Death in the Mouse Retina

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Kota Sato; Yukihiro Shiga; Yurika Nakagawa; Kosuke Fujita; Koji M. Nishiguchi; Hiroshi Tawarayama; Namie Murayama; Shigeto Maekawa; Takeshi Yabana; Kazuko Omodaka; Shota Katayama; Qiwei Feng; Satoru Tsuda; Toru Nakazawa
TAGS: optic nerve injuries, mice, optic nerve, retina, crispr
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3943-3951. doi: 10.1167/iovs.18-23784

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Most contributing quantified ocular parameters for classification of glaucomatous optic disc shape

Masahiro Akiba; Guangzhou An; Hideo Yokota; Kazuko Omodaka; Satoru Tsuda; Yukihiro shiga; naoko takada; Tsutomu Kikawa; Hidetoshi Takahashi; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1718. doi:

ARVO Annual Meeting Abstract July 2018

Refractory glaucoma treated with endolaser cyclophotocoagulation during pars plana vitrectomy

Nana Takahashi; Yu Yokoyama; Hiroshi Kunikata; Koji M NIshiguchi; Fumihiko Nitta; Takayuki Takeshita; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6105. doi:

ARVO Annual Meeting Abstract July 2018

Sustained release of Tafluprost with a newly developed drug delivery system protects retinal ganglion cells in rats after optic nerve transection

Yurika Nakagawa; Kota Sato; Kazuko Omodaka; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6113. doi:

ARVO Annual Meeting Abstract July 2018

Hesperidin has an anti-inflammatory effect after NMDA-induced retinal injury in mice

Taimu Sato; Kota Sato; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6120. doi:

ARVO Annual Meeting Abstract July 2018

Ecel1 expression is promoted by damage to axonal flow and protects retinal ganglion cells after optic nerve crush in mice

Kota Sato; Yurika Nakagawa; Hiroshi Tawarayama; Namie Murayama; Yukihiro shiga; Kosuke Fujita; Koji M NIshiguchi; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6138. doi:

ARVO Annual Meeting Abstract July 2018

Assisting glaucoma diagnosis with optical coherence tomography and color fundus images using machine learning approach

Maiko Abe; Kazuko Omodaka; Guangzhou An; Tsutomu Kikawa; Masahiro Akiba; Hideo Yokota; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2079. doi:

ARVO Annual Meeting Abstract July 2018

The Taiwa Study: Association between optical coherence tomography angiography measurements of the retinal peripapillary capillaries and macular capillary plexus in normal subjects

Hiroshi Kunikata; Toshifumi Asano; Naoko Aizawa; Risa Sato; Naoki Kiyota; Yukihiro shiga; Keiichi Kato; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3189. doi:

ARVO Annual Meeting Abstract July 2018

The association between oxidative stress and circumpapillary retinal nerve fiber layer thickness in patients with normal-tension glaucoma

Noriko Himori; Taiki Kokubun; Yukihiro Shiga; Kazuko Omodaka; Hiroshi Kunikata; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3725. doi:

ARVO Annual Meeting Abstract July 2018

Efficacy of hyperbaric oxygen treatment for central retinal artery occlusion and factors associated with its visual outcome

Masayuki Yasuda; Hajime Sato; Kazuki Hashimoto; Noriyuki Suzuki; Takehiro Hariya; Hiroko Nakayama; Toshifumi Asano; Masanori Munakata; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4294. doi:

ARVO Annual Meeting Abstract July 2018

The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow

Naoki Kiyota; Yukihiro shiga; Kohei Ichinohasama; Shiori Suzuki; Minami Yoshida; Naoto Honda; Hiroshi Kunikata; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5082. doi:

Glaucoma July 2018

The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow

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Naoki Kiyota; Yukihiro Shiga; Kohei Ichinohasama; Masayuki Yasuda; Naoko Aizawa; Kazuko Omodaka; Naoto Honda; Hiroshi Kunikata; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3488-3496. doi: 10.1167/iovs.18-23872

Includes: Supplemental Content

Retina February 2018

Discovery of a Cynomolgus Monkey Family With Retinitis Pigmentosa

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Yasuhiro Ikeda; Koji M. Nishiguchi; Fuyuki Miya; Nobuhiro Shimozawa; Jun Funatsu; Shunji Nakatake; Kohta Fujiwara; Takashi Tachibana; Yusuke Murakami; Toshio Hisatomi; Shigeo Yoshida; Yasuhiro Yasutomi; Tatsuhiko Tsunoda; Toru Nakazawa; Tatsuro Ishibashi; Koh-Hei Sonoda
TAGS: cercopithecidae, family, macaca fascicularis, retinitis pigmentosa, eye, fundus photography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):826-830. doi: 10.1167/iovs.17-22958

Retinal Cell Biology February 2018

Culture Systems of Dissociated Mouse and Human Pluripotent Stem Cell–Derived Retinal Ganglion Cells Purified by Two-Step Immunopanning

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Wataru Kobayashi; Akishi Onishi; Hung-Ya Tu; Yuji Takihara; Michiru Matsumura; Kazuko Tsujimoto; Masaru Inatani; Toru Nakazawa; Masayo Takahashi
TAGS: immunohistochemistry, organoids, retinal ganglion cells, mice, retina, stem cells, pluripotent, neuronal outgrowth
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):776-787. doi: 10.1167/iovs.17-22406

Includes: Supplemental Content

Retina February 2018

Pharmacokinetic and Safety Evaluation of a Transscleral Sustained Unoprostone Release Device in Monkey Eyes

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Nobuhiro Nagai; Shinji Yamada; Junichi Kawasaki; Eri Koyanagi; Saaya Saijo; Hirokazu Kaji; Matsuhiko Nishizawa; Toru Nakazawa; Toshiaki Abe
TAGS: cercopithecidae, electroretinography, safety, eye, intraocular pressure, unoprostone isopropyl, implantation procedure, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):644-652. doi: 10.1167/iovs.17-22429

Includes: Multimedia, Supplemental Content

Articles January 2018

Preperimetric Glaucoma Prospective Study (PPGPS): Predicting Visual Field Progression With Basal Optic Nerve Head Blood Flow in Normotensive PPG Eyes

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Yukihiro Shiga; Naoko Aizawa; Satoru Tsuda; Yu Yokoyama; Kazuko Omodaka; Hiroshi Kunikata; Tomoki Yasui; Keiichi Kato; Hiroaki Kurashima; Etsuyo Miyamoto; Masayo Hashimoto; Toru Nakazawa
TAGS: vascular flow, glaucoma, optic disk, prospective studies, visual fields, eye
Trans. Vis. Sci. Tech.. 2018; 7(1):11. doi: 10.1167/tvst.7.1.11

Glaucoma August 2017

Determinants and Characteristics of Bruch's Membrane Opening and Bruch's Membrane Opening–Minimum Rim Width in a Normal Japanese Population

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Makoto Araie; Aiko Iwase; Kazuhisa Sugiyama; Toru Nakazawa; Goji Tomita; Masanori Hangai; Yasuo Yanagi; Hiroshi Murata; Hidenobu Tanihara; Claude F. Burgoyne; Balwantray C. Chauhan
TAGS: glaucoma, bruch's basal membrane, optic disk, eye, retinal nerve fiber layer, japanese, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4106-4113. doi: 10.1167/iovs.17-22057

Glaucoma June 2017

The Effect of Systemic Hyperoxia on Optic Nerve Head Blood Flow in Primary Open-Angle Glaucoma Patients

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Naoki Kiyota; Yukihiro Shiga; Shiori Suzuki; Marika Sato; Naoko Takada; Shigeto Maekawa; Kazuko Omodaka; Kazuichi Maruyama; Hiroshi Kunikata; Toru Nakazawa
TAGS: oxygen, vascular flow, inspiration, glaucoma, open-angle glaucoma, hyperoxia, optic disk, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3181-3188. doi: 10.1167/iovs.17-21648

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Sectoral Differences in the Association of Optic Nerve Head Blood Flow and Glaucomatous Visual Field Defect Severity and Progression

Macular Dystrophy and Cone-Rod Dystrophy Caused by Mutations in the RP1 Gene: Extending the RP1 Disease Spectrum

Ecel1 Knockdown With an AAV2-Mediated CRISPR/Cas9 System Promotes Optic Nerve Damage-Induced RGC Death in the Mouse Retina

Most contributing quantified ocular parameters for classification of glaucomatous optic disc shape

Refractory glaucoma treated with endolaser cyclophotocoagulation during pars plana vitrectomy

Sustained release of Tafluprost with a newly developed drug delivery system protects retinal ganglion cells in rats after optic nerve transection

Hesperidin has an anti-inflammatory effect after NMDA-induced retinal injury in mice

Ecel1 expression is promoted by damage to axonal flow and protects retinal ganglion cells after optic nerve crush in mice

Assisting glaucoma diagnosis with optical coherence tomography and color fundus images using machine learning approach

The Taiwa Study: Association between optical coherence tomography angiography measurements of the retinal peripapillary capillaries and macular capillary plexus in normal subjects

The association between oxidative stress and circumpapillary retinal nerve fiber layer thickness in patients with normal-tension glaucoma

Efficacy of hyperbaric oxygen treatment for central retinal artery occlusion and factors associated with its visual outcome

The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow

The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow

Discovery of a Cynomolgus Monkey Family With Retinitis Pigmentosa

Culture Systems of Dissociated Mouse and Human Pluripotent Stem Cell–Derived Retinal Ganglion Cells Purified by Two-Step Immunopanning

Pharmacokinetic and Safety Evaluation of a Transscleral Sustained Unoprostone Release Device in Monkey Eyes

Preperimetric Glaucoma Prospective Study (PPGPS): Predicting Visual Field Progression With Basal Optic Nerve Head Blood Flow in Normotensive PPG Eyes

Determinants and Characteristics of Bruch's Membrane Opening and Bruch's Membrane Opening–Minimum Rim Width in a Normal Japanese Population

The Effect of Systemic Hyperoxia on Optic Nerve Head Blood Flow in Primary Open-Angle Glaucoma Patients

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