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Anatomy and Pathology/Oncology October 2019

Cyclin-Dependent Kinase Inhibitor 2b Mediates Excitotoxicity-Induced Death of Retinal Ganglion Cells

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Hiroshi Tawarayama; Qiwei Feng; Namie Murayama; Noriyuki Suzuki; Toru Nakazawa
TAGS: cdkn2b gene, genes, p16, n-methylaspartate, protein p16, excitotoxicity, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4479-4488. doi: https://doi.org/10.1167/iovs.19-27396

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Micro-homology-mediated end joining allows precise excision-insertion genome editing by a single adeno-associated virus vector to restore visual function in blind mice

Koji M Nishiguchi; Kosuke Fujita; Shota Katayama; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4225. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Sectoral association between postoperative retinal sensitivity and preoperative macular vessel density in surgery for idiopathic epiretinal membrane

Urara Osada; Hiroshi Kunikata; Masayuki Yasuda; Kazuki Hashimoto; Naoko Aizawa; Koji Nishiguchi; Toshiaki Abe; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4536. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Evaluation of glaucoma diagnosis machine learning models based on color optical coherence tomography and color fundus images

Masahiro Akiba; Guangzhou An; Hideo yokota; Kazuko Omodaka; Kazuki Hashimoto; Satoru Tsuda; Yukihiro Shiga; naoko takada; tsutomu kikawa; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1298. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Prediction of glaucomatous visual field progression by genetic variants associated with primary open-angle glaucoma

Fumihiko Mabuchi; Yoichi Sakurada; Kenji Kashiwagi; Mitsuko Takamoto; Makoto Aihara; Takeshi Iwata; Kazuki Hashimoto; Kota Sato; Yukihiro Shiga; Koji Nishiguchi; Toru Nakazawa; Masato Akiyama; Kazuhide Kawase; Mineo Ozaki; Makoto Araie

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1601. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Genetic risk score is associated with retinal nerve fiber layer thickness and severe glaucoma in Japanese normal-tension glaucoma patients

Yukihiro Shiga; Kazuki Hashimoto; Kota Sato; Koji Nishiguchi; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1605. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Associations between clinical features and risk alleles in Japanese glaucoma susceptibility loci

Kazuki Hashimoto; Yukihiro Shiga; Koji Nishiguchi; Masahiro Miyake; Kenji Yamashiro; Yosuke Kawai; Masao Nagasaki; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1625. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

The effectiveness of continuous positive airway pressure therapy in glaucoma patients with obstructive sleep apnea syndrome

Noriko Himori; Erika Yamada; Hiromasa Ogawa; Masakazu Ichinose; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2451. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Detecting glaucomatous change with magnetic resonance imaging of the brain primary visual cortex.

Akio Yamada; Kazuko Omodaka; Yasuko Tatewaki; Noriko Himori; Izumi Matsudaira; Taki Yasuyuki; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5539. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

The association between oxidative stress and corneal hysteresis in patients with glaucoma

Keiko Uchida; Noriko Himori; Hashimoto Kazuki; Maki Inoue-Yanagimachi; Naoki Kiyota; Marika Sato; Shigeto Maekawa; Yukihiro Shiga; Satoru Tsuda; Kazuko Omodaka; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5648. doi: https://doi.org/

Glaucoma June 2019

Sectoral Differences in the Association of Optic Nerve Head Blood Flow and Glaucomatous Visual Field Defect Severity and Progression

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Naoki Kiyota; Yukihiro Shiga; Masayuki Yasuda; Naoko Aizawa; Kazuko Omodaka; Satoru Tsuda; Hiroshi Kunikata; Toru Nakazawa
TAGS: glaucomatous visual field defect, optic disk, vascular flow, body tissue
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2650-2658. doi: https://doi.org/10.1167/iovs.19-27230

Includes: Supplemental Content

Genetics March 2019

Macular Dystrophy and Cone-Rod Dystrophy Caused by Mutations in the RP1 Gene: Extending the RP1 Disease Spectrum

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Sanne K. Verbakel; Ramon A. C. van Huet; Anneke I. den Hollander; Maartje J. Geerlings; Eveline Kersten; B. Jeroen Klevering; Caroline C. W. Klaver; Astrid S. Plomp; Nieneke L. Wesseling; Arthur A. B. Bergen; Konstantinos Nikopoulos; Carlo Rivolta; Yasuhiro Ikeda; Koh-Hei Sonoda; Yuko Wada; Camiel J. F. Boon; Toru Nakazawa; Carel B. Hoyng; Koji M. Nishiguchi
TAGS: phenotype, mutation, family, genes, retinitis pigmentosa, genetics, age-related macular degeneration, macular dystrophy
Invest. Ophthalmol. Vis. Sci.. 2019; 60(4):1192-1203. doi: https://doi.org/10.1167/iovs.18-26084

Includes: Supplemental Content

Retinal Cell Biology August 2018

Ecel1 Knockdown With an AAV2-Mediated CRISPR/Cas9 System Promotes Optic Nerve Damage-Induced RGC Death in the Mouse Retina

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Kota Sato; Yukihiro Shiga; Yurika Nakagawa; Kosuke Fujita; Koji M. Nishiguchi; Hiroshi Tawarayama; Namie Murayama; Shigeto Maekawa; Takeshi Yabana; Kazuko Omodaka; Shota Katayama; Qiwei Feng; Satoru Tsuda; Toru Nakazawa
TAGS: optic nerve injuries, mice, optic nerve, retina, crispr
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):3943-3951. doi: https://doi.org/10.1167/iovs.18-23784

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Most contributing quantified ocular parameters for classification of glaucomatous optic disc shape

Masahiro Akiba; Guangzhou An; Hideo Yokota; Kazuko Omodaka; Satoru Tsuda; Yukihiro shiga; naoko takada; Tsutomu Kikawa; Hidetoshi Takahashi; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1718. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Refractory glaucoma treated with endolaser cyclophotocoagulation during pars plana vitrectomy

Nana Takahashi; Yu Yokoyama; Hiroshi Kunikata; Koji M NIshiguchi; Fumihiko Nitta; Takayuki Takeshita; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6105. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Sustained release of Tafluprost with a newly developed drug delivery system protects retinal ganglion cells in rats after optic nerve transection

Yurika Nakagawa; Kota Sato; Kazuko Omodaka; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6113. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Hesperidin has an anti-inflammatory effect after NMDA-induced retinal injury in mice

Taimu Sato; Kota Sato; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6120. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Ecel1 expression is promoted by damage to axonal flow and protects retinal ganglion cells after optic nerve crush in mice

Kota Sato; Yurika Nakagawa; Hiroshi Tawarayama; Namie Murayama; Yukihiro shiga; Kosuke Fujita; Koji M NIshiguchi; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6138. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Assisting glaucoma diagnosis with optical coherence tomography and color fundus images using machine learning approach

Maiko Abe; Kazuko Omodaka; Guangzhou An; Tsutomu Kikawa; Masahiro Akiba; Hideo Yokota; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2079. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow

Naoki Kiyota; Yukihiro shiga; Kohei Ichinohasama; Shiori Suzuki; Minami Yoshida; Naoto Honda; Hiroshi Kunikata; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5082. doi: https://doi.org/

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Cyclin-Dependent Kinase Inhibitor 2b Mediates Excitotoxicity-Induced Death of Retinal Ganglion Cells

Micro-homology-mediated end joining allows precise excision-insertion genome editing by a single adeno-associated virus vector to restore visual function in blind mice

Sectoral association between postoperative retinal sensitivity and preoperative macular vessel density in surgery for idiopathic epiretinal membrane

Evaluation of glaucoma diagnosis machine learning models based on color optical coherence tomography and color fundus images

Prediction of glaucomatous visual field progression by genetic variants associated with primary open-angle glaucoma

Genetic risk score is associated with retinal nerve fiber layer thickness and severe glaucoma in Japanese normal-tension glaucoma patients

Associations between clinical features and risk alleles in Japanese glaucoma susceptibility loci

The effectiveness of continuous positive airway pressure therapy in glaucoma patients with obstructive sleep apnea syndrome

Detecting glaucomatous change with magnetic resonance imaging of the brain primary visual cortex.

The association between oxidative stress and corneal hysteresis in patients with glaucoma

Sectoral Differences in the Association of Optic Nerve Head Blood Flow and Glaucomatous Visual Field Defect Severity and Progression

Macular Dystrophy and Cone-Rod Dystrophy Caused by Mutations in the RP1 Gene: Extending the RP1 Disease Spectrum

Ecel1 Knockdown With an AAV2-Mediated CRISPR/Cas9 System Promotes Optic Nerve Damage-Induced RGC Death in the Mouse Retina

Most contributing quantified ocular parameters for classification of glaucomatous optic disc shape

Refractory glaucoma treated with endolaser cyclophotocoagulation during pars plana vitrectomy

Sustained release of Tafluprost with a newly developed drug delivery system protects retinal ganglion cells in rats after optic nerve transection

Hesperidin has an anti-inflammatory effect after NMDA-induced retinal injury in mice

Ecel1 expression is promoted by damage to axonal flow and protects retinal ganglion cells after optic nerve crush in mice

Assisting glaucoma diagnosis with optical coherence tomography and color fundus images using machine learning approach

The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow

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