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ARVO Annual Meeting Abstract July 2018

A Refillable Drug Delivery Device to the Retina

Nobuhiro Nagai; Saaya Saijo; Yuanhui Song; Hirokazu Kaji; Matsuhiko Nishizawa; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5704. doi:

Retina February 2018

Pharmacokinetic and Safety Evaluation of a Transscleral Sustained Unoprostone Release Device in Monkey Eyes

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Nobuhiro Nagai; Shinji Yamada; Junichi Kawasaki; Eri Koyanagi; Saaya Saijo; Hirokazu Kaji; Matsuhiko Nishizawa; Toru Nakazawa; Toshiaki Abe
TAGS: cercopithecidae, electroretinography, safety, eye, intraocular pressure, unoprostone isopropyl, implantation procedure, optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):644-652. doi: 10.1167/iovs.17-22429

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2017

Biodegradable injectable sheet as transscleral drug delivery system

Nobuhiro Nagai; Zhaleh Kashkouli Nezhad; Saaya Saijo; Hirokazu Kaji; Matsuhiko Nishizawa; Toru Nakazawa; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4464. doi:

ARVO Annual Meeting Abstract June 2017

Non-histone nuclear protein play important roles for photoreceptor function and experimental choroidal neovascularization

Toshiaki Abe; Aya Katsuyama; Shinji Yamada; Nobuhiro Nagai; Reiko Daigaku; Kenta Ishida; Yuki Katsukura

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5228. doi:

Retina December 2016

Long-Term Protection of Genetically Ablated Rabbit Retinal Degeneration by Sustained Transscleral Unoprostone Delivery

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Nobuhiro Nagai; Eri Koyanagi; Yasuko Izumida; Junjun Liu; Aya Katsuyama; Hirokazu Kaji; Matsuhiko Nishizawa; Noriko Osumi; Mineo Kondo; Hiroko Terasaki; Yukihiko Mashima; Toru Nakazawa; Toshiaki Abe
TAGS: polymerase chain reaction, in situ hybridization, electroretinography, placebos, oryctolagus cuniculus, retinal degeneration, rna-directed dna polymerase, eye, retina, unoprostone isopropyl
Invest. Ophthalmol. Vis. Sci.. 2016; 57(15):6527-6538. doi: 10.1167/iovs.16-20453

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Protective Effects of Sustained Unoprostone Release Device in Rhodopsin Pro347Leu Transgenic Rabbits

Nobuhiro Nagai; Yasuko Izumida; Hirokazu Kaji; Matsuhiko Nishizawa; Aya Katsuyama; Shinji Yamada; Toru Nakazawa; Mineo Kondo; Hiroko Terasaki; Yukihiko Mashima; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4017. doi:

ARVO Annual Meeting Abstract September 2016

A non-histone nuclear protein enhances VEGF expression and choroidal neovascularization

Toshiaki Abe; Aya Katsuyama; Shinji Yamada; Yuki Katsukura; Zhaleh Nezhad; Nobuhiro Nagai

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5793. doi:

ARVO Annual Meeting Abstract June 2015

Ranibizumab Delivery Device Using Polyethyleneglycol Dimethacrylates

Toshiaki Abe; Aya Katsuyama; Hideyuki Onami; Toru Nakazawa; Nobuhiro Nagai

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4146. doi:

ARVO Annual Meeting Abstract June 2015

Pharmacokinetic and Safety Evaluation of a Transscleral Sustained Unoprostone Release Device

Nobuhiro Nagai; Yasuko Izumida; Eri Koyanagi; Hirokazu Kaji; Matsuhiko Nishizawa; Takahito Imagawa; Akiko Morikawa; Toru Nakazawa; Yukihiko Mashima; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4153. doi:

ARVO Annual Meeting Abstract April 2014

Sustained clotrimazole release attenuates light-induced retinal damage through modulation of reactive oxygen species (ROS) and mitogen-activated protein kinases (MAPKs)

Zhaleh Kashkouli Nezhad; Nobuhiro Nagai; Kotaro Yamamoto; Hideyuki Saya; Toru Nakazawa; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):483. doi:

ARVO Annual Meeting Abstract April 2014

Controlled Transscleral Dual-drug Delivery by a Polymeric Device Reduces Light-induced Retinal Damage

Nobuhiro Nagai; Hirokazu Kaji; Zhaleh Kashkouli Nezhad; Kaori Sampei; Satoru Iwata; Matsuhiko Nishizawa; Yukihiko Mashima; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):446. doi:

ARVO Annual Meeting Abstract April 2014

Local Delivery of an Engineered Epithelial Monolayer by Micropatterned Polymeric Nanosheets

Hirokazu Kaji; Toshinori Fujie; Nobuhiro Nagai; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1449. doi:

ARVO Annual Meeting Abstract June 2013

Protective Effects of Transscleral Drug Delivery Device Against Photoreceptor Cell Death in S334ter Rhodopsin Mutant Rats

Nobuhiro Nagai; Hirokazu Kaji; Hideyuki Onami; Takuya Yamada; Yuki Katsukura; Yumi Ishikawa; Matsuhiko Nishizawa; Yukihiko Mashima; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5064. doi:

ARVO Annual Meeting Abstract March 2012

Protective Effects of Transscleral Drug Delivery Device Against Light-induced Retinal Damage in Rats

Nobuhiro Nagai; Hideyuki Onami; Hirokazu Kaji; Takuya Yamada; Yuki Katsukura; Machiko Sato; Yumi Ishikawa; Toru Nakazawa; Matsuhiko Nishizawa; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):470. doi:

ARVO Annual Meeting Abstract March 2012

Suppression of Rat Choroidal Neovascularization by Transscleral Vasohibin-1 Delivery Device

Hideyuki Onami; Nobuhiro Nagai; Ryosuke Wakusawa; Hirokazu Kaji; Takuya Yamada; Yumi Ishikawa; Matauhiko Nishizawa; Yasufumi Sato; Toru Nakazawa; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):475. doi:

ARVO Annual Meeting Abstract March 2012

Retrospective Comparison Of 23- And 25-gauge microincision vitrectomy Surgery to 20-gauge vitrectomy For The Repair Of Macular Hole retinal Detachment

Wataru Kobayashi; Hiroshi Kunikata; Toshiaki Abe; Toru Nakazawa

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3772. doi:

Retinal Cell Biology May 2011

Suppression of Choroidal Neovascularization by Vasohibin-1, a Vascular Endothelium–Derived Angiogenic Inhibitor

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Ryosuke Wakusawa; Toshiaki Abe; Hajime Sato; Hikaru Sonoda; Masaaki Sato; Yuuichi Mitsuda; Tomoaki Takakura; Tomi Fukushima; Hideyuki Onami; Nobuhiro Nagai; Yumi Ishikawa; Kohji Nishida; Yasufumi Sato
TAGS: angiogenesis, choroidal neovascularization, lasers, eye, mice
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):3272-3280. doi: 10.1167/iovs.10-6295

ARVO Annual Meeting Abstract April 2011

Evaluation of Ocular Tissue Distribution of Drugs Delivered Transsclerally From A Non-biodegradable Polymeric Capsule Device

Nobuhiro Nagai; Takeaki Kawashima; Hirokazu Kaji; Hideyuki Onami; Norihiro Kumasaka; Matsuhiko Nishizawa; Toshiaki Abe

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3236. doi:

ARVO Annual Meeting Abstract April 2011

Suppression of Choroidal Neovascularization by Intravitreal Vasohibin-1 in Monkey Eyes

Toshiaki Abe; Hideyuki Onami; Nobuhiro Nagai; Norihiro Kumasaka; Ryosuke Wakusawa; Yumi Ishikawa; Shigeki Machida; Hikaru Sonoda; Yasufumi Sato

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4011. doi:

Retinal Cell Biology August 2008

Topical Doxycycline Can Induce Expression of BDNF in Transduced Retinal Pigment Epithelial Cells Transplanted into the Subretinal Space

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Toshiaki Abe; Ryosuke Wakusawa; Haruka Seto; Nobuharu Asai; Takae Saito; Kohji Nishida
TAGS: doxycycline, brain-derived neurotrophic factor, transplantation, eyedrops, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2008; 49(8):3631-3639. doi: 10.1167/iovs.07-0947

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A Refillable Drug Delivery Device to the Retina

Pharmacokinetic and Safety Evaluation of a Transscleral Sustained Unoprostone Release Device in Monkey Eyes

Biodegradable injectable sheet as transscleral drug delivery system

Non-histone nuclear protein play important roles for photoreceptor function and experimental choroidal neovascularization

Long-Term Protection of Genetically Ablated Rabbit Retinal Degeneration by Sustained Transscleral Unoprostone Delivery

Protective Effects of Sustained Unoprostone Release Device in Rhodopsin Pro347Leu Transgenic Rabbits

A non-histone nuclear protein enhances VEGF expression and choroidal neovascularization

Ranibizumab Delivery Device Using Polyethyleneglycol Dimethacrylates

Pharmacokinetic and Safety Evaluation of a Transscleral Sustained Unoprostone Release Device

Sustained clotrimazole release attenuates light-induced retinal damage through modulation of reactive oxygen species (ROS) and mitogen-activated protein kinases (MAPKs)

Controlled Transscleral Dual-drug Delivery by a Polymeric Device Reduces Light-induced Retinal Damage

Local Delivery of an Engineered Epithelial Monolayer by Micropatterned Polymeric Nanosheets

Protective Effects of Transscleral Drug Delivery Device Against Photoreceptor Cell Death in S334ter Rhodopsin Mutant Rats

Protective Effects of Transscleral Drug Delivery Device Against Light-induced Retinal Damage in Rats

Suppression of Rat Choroidal Neovascularization by Transscleral Vasohibin-1 Delivery Device

Retrospective Comparison Of 23- And 25-gauge microincision vitrectomy Surgery to 20-gauge vitrectomy For The Repair Of Macular Hole retinal Detachment

Suppression of Choroidal Neovascularization by Vasohibin-1, a Vascular Endothelium–Derived Angiogenic Inhibitor

Evaluation of Ocular Tissue Distribution of Drugs Delivered Transsclerally From A Non-biodegradable Polymeric Capsule Device

Suppression of Choroidal Neovascularization by Intravitreal Vasohibin-1 in Monkey Eyes

Topical Doxycycline Can Induce Expression of BDNF in Transduced Retinal Pigment Epithelial Cells Transplanted into the Subretinal Space

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