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Lens May 2022

Oxysterol Compounds in Mouse Mutant αA- and αB-Crystallin Lenses Can Improve the Optical Properties of the Lens

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Kehao Wang; Masato Hoshino; Kentaro Uesugi; Naoto Yagi; Barbara K. Pierscionek; Usha P. Andley
TAGS: crystallins, lens (device), lens, crystalline, mice, optics, oxysterols, refractive index, alpha-crystallin b chain, cataract
Invest. Ophthalmol. Vis. Sci.. 2022; 63(5):15. https://doi.org/10.1167/iovs.63.5.15

Includes: Supplemental Content

Lens August 2019

Mechanism of Action of VP1-001 in cryAB(R120G)-Associated and Age-Related Cataracts

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Kathleen S. Molnar; Bryan M. Dunyak; Bonnie Su; Yevgeniy Izrayelit; Brittney McGlasson-Naumann; Paul D. Hamilton; Mingxing Qian; Douglas F. Covey; Jason E. Gestwicki; Leah N. Makley; Usha P. Andley
TAGS: alpha-crystallin b chain, lens (device), lens, crystalline, mice, cataract, senile
Invest. Ophthalmol. Vis. Sci.. 2019; 60(10):3320-3331. https://doi.org/10.1167/iovs.18-25647

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Discovery of non-sterol αB-crystallin ligands as potential cataract therapeutics

Bryan Dunyak; Bonnie Su; Kathleen Molnar; Paul Hamilton; Stephanie Bozeman; Stacy Li; Linda Liu; Usha P Andley; Leah Makley

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5691.

ARVO Annual Meeting Abstract June 2017

Towards a Mechanism of Action of VP1-001 in R120G cryAB-Associated Cataracts

Yevgeniy Izrayelit; Brittney McGlasson; Paul David Hamilton; Mingxing Qian; Kathleen Molnar; Douglas Covey; Jason Gestwicki; Leah Makley; Usha P Andley

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5302.

ARVO Annual Meeting Abstract September 2016

α-Crystallin binding and associations with putative substrates

Paul David Hamilton; Brittney McGlasson; Usha P Andley

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):724.

Lens October 2011

Inhibition of Lens Photodamage by UV-Absorbing Contact Lenses

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Usha P. Andley; James P. Malone; R. Reid Townsend
TAGS: contact lenses, lens (device), lens, crystalline, proteins, ultraviolet b radiation, ultraviolet rays, photodamaged skin, crystallins
Invest. Ophthalmol. Vis. Sci.. 2011; 52(11):8330-8341. https://doi.org/10.1167/iovs.11-7633

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2011

Immunological Detection Of NFK In Photooxided Lens α-crystallin

Joan E. Roberts; Marilyn Ehrenshaft; Baozhong Zhao; Usha P. Andley; Ronald P. Mason

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4740.

ARVO Annual Meeting Abstract April 2011

Assessment of Autophagy in a Mouse Model for Human Hereditary Cataract and Myopathy

Matthew G. Bartley; Jeong J. Sun; Conrad C. Weihl; Usha P. Andley

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):803.

ARVO Annual Meeting Abstract April 2011

An Autosomal Dominant Mutation in AlphaB-Crystallin Causes Cataracts and Myopathy in Mice

Usha P. Andley; Paul D. Hamilton; Nathan Ravi; Conrad C. Weihl

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2087.

ARVO Annual Meeting Abstract April 2010

Screening for Ocular Phototoxicity of Fluoroquinolone Antibiotics

J. E. Roberts; C. F. Chignell; U. P. Andley; B. Zhao

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):1187.

ARVO Annual Meeting Abstract April 2009

The Effect of R120G Mutation in AlphaB-Crystallin on the Mechanical Properties of Mouse Lenses

P. A. Sistla; M. A. Reilly; U. P. Andley; N. Ravi

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):2107.

ARVO Annual Meeting Abstract April 2009

Phototoxicity and Cytotoxicity of Cyclodextrin Complexed Fullerene [(-CyD)2/C60] Towards Human Lens Epithelial Cells

J. E. Roberts; B. Zhao; Y.-Y. He; U. P. Andley; C. F. Chignell

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):2125.

ARVO Annual Meeting Abstract April 2009

Protection of UVB-Induced Damage in Cultured Lens Epithelial Cells by UV-Absorbing Soft Contact Lenses

U. P. Andley

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):2537.

ARVO Annual Meeting Abstract May 2008

Evaluation of in vitro Effects of Triamcinolone Acetonide and Dexamethasone on Human Lens Epithelial Cells

A. Pirouzmanesh; A. Sharma; A. Pirouzmanesh; U. P. Andley; M. C. Kenney; B. D. Kuppermann

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):2776.

ARVO Annual Meeting Abstract May 2008

Differential Toxicity of Ultraviolet Light on Human Retinal Pigment Epithelial, Rat Retinal Neurosensory and Human Lens Epithelial Cells in vitro

S. Mansoor; A. Sharma; A. Jayaprakash Patil; M. F. Estrago; G. M. Seigel; U. P. Andley; M. C. Kenney; B. D. Kuppermann

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):3975.

ARVO Annual Meeting Abstract May 2008

A Knockin Mouse Model for the R120G Mutation in AlphaB-Crystallin

U. P. Andley; F. Bai; J.-H. Xi

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):5023.

ARVO Annual Meeting Abstract May 2007

An AlphaA-Crystallin Mutation in a Mouse Model for Congenital Human Cataract

U. P. Andley; J. Xi; F. Bai

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):1522.

Lens November 2003

Proteome Analysis of Lens Epithelia, Fibers, and the HLE B-3 Cell Line

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Shuh-Tuan Wang-Su; Ashley L. McCormack; Shaojun Yang; Matthew R. Hosler; April Mixon; Michael A. Riviere; Phillip A. Wilmarth; Usha P. Andley; Donita Garland; Hong Li; Larry L. David; B. J. Wagner
TAGS: cell lines, crystallins, gel, lens (device), lens, crystalline, proteins, proteome, epithelium
Invest. Ophthalmol. Vis. Sci.. 2003; 44(11):4829-4836. https://doi.org/10.1167/iovs.03-0556

Lens June 2003

Metabolism of Lipid Derived Aldehyde, 4-Hydroxynonenal in Human Lens Epithelial Cells and Rat Lens

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Sanjeev Choudhary; Sanjay Srivastava; Tianlin Xiao; Usha P. Andley; Satish K. Srivastava; Naseem H. Ansari
TAGS: aldehydes, epithelial cells, high pressure liquid chromatography procedure, lens (device), lens, crystalline, lipids, metabolism, hereditary neuralgic amyotrophy, human neutrophil antigens
Invest. Ophthalmol. Vis. Sci.. 2003; 44(6):2675-2682. https://doi.org/10.1167/iovs.02-0965

Lens February 2002

Protection of HLE B-3 Cells against Hydrogen Peroxide– and Naphthalene-Induced Lipid Peroxidation and Apoptosis by Transfection with hGST A1 and hGST A2

PDF

Yusong Yang; Rajendra Sharma; Ji-Zhong Cheng; Manjit K. Saini; Naseem H. Ansari; Usha P. Andley; Sanjay Awasthi; Yogesh C. Awasthi
TAGS: apoptosis, hydrogen peroxide, lipid peroxidation, naphthalenes, transfection, tissue membrane, antibodies, western blotting, immunoprecipitation, proteins
Invest. Ophthalmol. Vis. Sci.. 2002; 43(2):434-445.

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Oxysterol Compounds in Mouse Mutant αA- and αB-Crystallin Lenses Can Improve the Optical Properties of the Lens

Mechanism of Action of VP1-001 in cryAB(R120G)-Associated and Age-Related Cataracts

Discovery of non-sterol αB-crystallin ligands as potential cataract therapeutics

Towards a Mechanism of Action of VP1-001 in R120G cryAB-Associated Cataracts

α-Crystallin binding and associations with putative substrates

Inhibition of Lens Photodamage by UV-Absorbing Contact Lenses

Immunological Detection Of NFK In Photooxided Lens α-crystallin

Assessment of Autophagy in a Mouse Model for Human Hereditary Cataract and Myopathy

An Autosomal Dominant Mutation in AlphaB-Crystallin Causes Cataracts and Myopathy in Mice

Screening for Ocular Phototoxicity of Fluoroquinolone Antibiotics

The Effect of R120G Mutation in AlphaB-Crystallin on the Mechanical Properties of Mouse Lenses

Phototoxicity and Cytotoxicity of Cyclodextrin Complexed Fullerene [(-CyD)2/C60] Towards Human Lens Epithelial Cells

Protection of UVB-Induced Damage in Cultured Lens Epithelial Cells by UV-Absorbing Soft Contact Lenses

Evaluation of in vitro Effects of Triamcinolone Acetonide and Dexamethasone on Human Lens Epithelial Cells

Differential Toxicity of Ultraviolet Light on Human Retinal Pigment Epithelial, Rat Retinal Neurosensory and Human Lens Epithelial Cells in vitro

A Knockin Mouse Model for the R120G Mutation in AlphaB-Crystallin

An AlphaA-Crystallin Mutation in a Mouse Model for Congenital Human Cataract

Proteome Analysis of Lens Epithelia, Fibers, and the HLE B-3 Cell Line

Metabolism of Lipid Derived Aldehyde, 4-Hydroxynonenal in Human Lens Epithelial Cells and Rat Lens

Protection of HLE B-3 Cells against Hydrogen Peroxide– and Naphthalene-Induced Lipid Peroxidation and Apoptosis by Transfection with hGST A1 and hGST A2

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