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Retinal Cell Biology October 2009

Association of Superoxide Anions with Retinal Pigment Epithelial Cell Apoptosis Induced by Mononuclear Phagocytes

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Dongli Yang; Susan G. Elner; Li-Ren Lin; Venkat N. Reddy; Howard R. Petty; Victor M. Elner
TAGS: apoptosis, mice, reticuloendothelial system, retinal pigment cell, phagocytes, superoxides, anions
Invest. Ophthalmol. Vis. Sci.. 2009; 50(10):4998-5005. https://doi.org/10.1167/iovs.09-3620

ARVO Annual Meeting Abstract May 2007

The Lens’ Circulation in 14-Month-Old GPX-1 KO and WT Mice

H. Wang; J. Gao; X. Sun; K. Varadaraj; M. Farrell; V. N. Reddy; R. T. Mathias

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):4218.

Biochemistry and Molecular Biology February 2007

Proteomic and Transcriptomic Analyses of Retinal Pigment Epithelial Cells Exposed to REF-1/TFPI-2

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Masahiko Shibuya; Haru Okamoto; Takehiro Nozawa; Jun Utsumi; Venkat N. Reddy; Hirotoshi Echizen; Yasuhiko Tanaka; Takeshi Iwata
TAGS: proteins, retinal pigment cell, tissue factor pathway inhibitor
Invest. Ophthalmol. Vis. Sci.. 2007; 48(2):516-521. https://doi.org/10.1167/iovs.06-0434

Retinal Cell Biology September 2005

SOD2 Protects against Oxidation-Induced Apoptosis in Mouse Retinal Pigment Epithelium: Implications for Age-Related Macular Degeneration

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Emiko Kasahara; Li-Ren Lin; Ye-Shih Ho; Venkat N. Reddy
TAGS: age-related macular degeneration, apoptosis, cytochrome c, enzymes, mice, mitochondria, oxidation, oxidative stress, retinal pigment cell, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2005; 46(9):3426-3434. https://doi.org/10.1167/iovs.05-0344

Physiology and Pharmacology January 2004

Purification, Molecular Cloning, and Expression of a Novel Growth-Promoting Factor for Retinal Pigment Epithelial Cells, REF-1/TFPI-2

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Yasuhiko Tanaka; Jun Utsumi; Mizuo Matsui; Tetsuo Sudo; Noriko Nakamura; Masato Mutoh; Akemi Kajita; Saburo Sone; Kazuteru Kigasawa; Masahiko Shibuya; Venkat N. Reddy; Qiang Zhang; Takeshi Iwata
TAGS: molecular cloning, retinal pigment cell, tissue factor pathway inhibitor
Invest. Ophthalmol. Vis. Sci.. 2004; 45(1):245-252. https://doi.org/10.1167/iovs.03-0230

Lens August 2003

The Effect of Up- and Downregulation of MnSOD Enzyme on Oxidative Stress in Human Lens Epithelial Cells

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Hironori Matsui; Li-Ren Lin; Ye-Shih Ho; Venkat N. Reddy
TAGS: down-regulation, enzymes, epithelial cells, lens, crystalline, oxidative stress, dna, complementary, dna
Invest. Ophthalmol. Vis. Sci.. 2003; 44(8):3467-3475. https://doi.org/10.1167/iovs.02-0830

Lens May 2003

Spectrum and Range of Oxidative Stress Responses of Human Lens Epithelial Cells to H 2 O 2 Insult

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Sumanta Goswami; Nancy L. Sheets; Jiři Zavadil; Bharesh K. Chauhan; Erwin P. Bottinger; Venkat N. Reddy; Marc Kantorow; Aleš Cvekl
TAGS: epithelial cells, genes, lens, crystalline, oxidative stress, proteins, enzymes
Invest. Ophthalmol. Vis. Sci.. 2003; 44(5):2084-2093. https://doi.org/10.1167/iovs.02-0882

Lens February 2003

Activation of Metallothioneins and α-Crystallin/sHSPs in Human Lens Epithelial Cells by Specific Metals and the Metal Content of Aging Clear Human Lenses

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John R. Hawse; Jonathan R. Cumming; Brian Oppermann; Nancy L. Sheets; Venkat N. Reddy; Marc Kantorow
TAGS: crystallins, lens, crystalline, metallothionein, metals, epithelial cells, aging, reverse transcriptase polymerase chain reaction
Invest. Ophthalmol. Vis. Sci.. 2003; 44(2):672-679. https://doi.org/10.1167/iovs.02-0018

Lens December 2001

Glutathione Peroxidase-1 Deficiency Leads to Increased Nuclear Light Scattering, Membrane Damage, and Cataract Formation in Gene-Knockout Mice

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Venkat N. Reddy; Frank J. Giblin; Li-Ren Lin; Loan Dang; Nalin J. Unakar; David C. Musch; Daniel L. Boyle; Larry J. Takemoto; Ye-Shih Ho; Tina Knoernschild; Anselm Juenemann; Elke Lütjen–Drecoll
TAGS: cataract, gene knockout techniques, glutathione, lens (device), lens, crystalline, mice, peroxidase, tissue membrane, slit lamp biomicroscopy, enzymes
Invest. Ophthalmol. Vis. Sci.. 2001; 42(13):3247-3255.

Lens November 2001

Lens Epithelium-Derived Growth Factor: Increased Survival and Decreased DNA Breakage of Human RPE Cells Induced by Oxidative Stress

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Hironori Matsui; Li-Ren Lin; Dhirendra P. Singh; Toshimichi Shinohara; Venkat N. Reddy
TAGS: dna, growth factor, oxidative stress, retinal pigment cell, lens (device), epithelium, lens, crystalline, ultraviolet b radiation, proteins
Invest. Ophthalmol. Vis. Sci.. 2001; 42(12):2935-2941.

Lens October 2001

Lovastatin-Induced Cytoskeletal Reorganization in Lens Epithelial Cells: Role of Rho GTPases

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Rupa Latha Maddala; Venkat N. Reddy; P. Vasantha Rao
TAGS: cytoskeleton, lens epithelial cell, lovastatin, rho gtp-binding proteins, actins
Invest. Ophthalmol. Vis. Sci.. 2001; 42(11):2610-2615.

Retinal Cell Biology April 2001

Lens Epithelium-Derived Growth Factor Promotes Photoreceptor Survival in Light-Damaged and RCS Rats

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Shigeki Machida; Prem Chaudhry; Toshimichi Shinohara; Dhirendra P. Singh; Venkat N. Reddy; Leo T. Chylack, Jr; Paul A. Sieving; Ronald A. Bush
TAGS: eye, growth factor, photoreceptors, rats, electroretinography, lens, crystalline, epithelium
Invest. Ophthalmol. Vis. Sci.. 2001; 42(5):1087-1095.

Lens September 2000

Impact of Aging and Hyperbaric Oxygen In Vivo on Guinea Pig Lens Lipids and Nuclear Light Scatter

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Douglas Borchman; Frank J. Giblin; Victor R. Leverenz; Venkat N. Reddy; Li-Ren Lin; Marta Cecilia Yappert; Daxin Tang; Li Li
TAGS: lens (device), lens, crystalline, lipids, guinea, oxidation
Invest. Ophthalmol. Vis. Sci.. 2000; 41(10):3061-3073.

Articles March 1998

TEMPOL protects against lens DNA strand breaks and cataract in the x-rayed rabbit.

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H Sasaki; L R Lin; T Yokoyama; M D Sevilla; V N Reddy; F J Giblin
TAGS: cataract, dna, lens (device), lens, crystalline, oryctolagus cuniculus
Invest. Ophthalmol. Vis. Sci.. 1998; 39(3):544-552.

Articles February 1998

The effect of aqueous humor ascorbate on ultraviolet-B-induced DNA damage in lens epithelium.

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V N Reddy; F J Giblin; L R Lin; B Chakrapani
TAGS: aqueous humor, dna damage, lens epithelium
Invest. Ophthalmol. Vis. Sci.. 1998; 39(2):344-350.

Articles October 1997

Role of small GTP-binding proteins in lovastatin-induced cataracts.

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P V Rao; W G Robison, Jr; F Bettelheim; L R Lin; V N Reddy; J S Zigler, Jr
TAGS: cataract, gtp-binding proteins, lovastatin
Invest. Ophthalmol. Vis. Sci.. 1997; 38(11):2313-2321.

Articles October 1995

Effects of growth factors on proliferation and differentiation in human lens epithelial cells in early subculture.

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N Ibaraki; L R Lin; V N Reddy
TAGS: epithelial cells, growth factor, lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 1995; 36(11):2304-2312.

Articles July 1993

Hypertonic stress increases NaK ATPase, taurine, and myoinositol in human lens and retinal pigment epithelial cultures.

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T Yokoyama; L R Lin; B Chakrapani; V N Reddy
TAGS: adenosine triphosphatases, epithelium, inositol, lens, crystalline, pigment, stress, taurine
Invest. Ophthalmol. Vis. Sci.. 1993; 34(8):2512-2517.

Articles June 1993

The effect of hypertonicity on aldose reductase, alpha B-crystallin, and organic osmolytes in the retinal pigment epithelium.

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L R Lin; D Carper; T Yokoyama; V N Reddy
TAGS: aldehyde reductase, alpha-crystallin b chain, hypertonicity, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 1993; 34(7):2352-2359.

Articles February 1993

Synthesis of lens capsule in long-term culture of human lens epithelial cells.

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T Arita; Y Murata; L R Lin; T Tsuji; V N Reddy
TAGS: epithelial cells, lens capsule, crystalline, lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 1993; 34(2):355-362.

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Association of Superoxide Anions with Retinal Pigment Epithelial Cell Apoptosis Induced by Mononuclear Phagocytes

The Lens’ Circulation in 14-Month-Old GPX-1 KO and WT Mice

Proteomic and Transcriptomic Analyses of Retinal Pigment Epithelial Cells Exposed to REF-1/TFPI-2

SOD2 Protects against Oxidation-Induced Apoptosis in Mouse Retinal Pigment Epithelium: Implications for Age-Related Macular Degeneration

Purification, Molecular Cloning, and Expression of a Novel Growth-Promoting Factor for Retinal Pigment Epithelial Cells, REF-1/TFPI-2

The Effect of Up- and Downregulation of MnSOD Enzyme on Oxidative Stress in Human Lens Epithelial Cells

Spectrum and Range of Oxidative Stress Responses of Human Lens Epithelial Cells to H 2 O 2 Insult

Activation of Metallothioneins and α-Crystallin/sHSPs in Human Lens Epithelial Cells by Specific Metals and the Metal Content of Aging Clear Human Lenses

Glutathione Peroxidase-1 Deficiency Leads to Increased Nuclear Light Scattering, Membrane Damage, and Cataract Formation in Gene-Knockout Mice

Lens Epithelium-Derived Growth Factor: Increased Survival and Decreased DNA Breakage of Human RPE Cells Induced by Oxidative Stress

Lovastatin-Induced Cytoskeletal Reorganization in Lens Epithelial Cells: Role of Rho GTPases

Lens Epithelium-Derived Growth Factor Promotes Photoreceptor Survival in Light-Damaged and RCS Rats

Impact of Aging and Hyperbaric Oxygen In Vivo on Guinea Pig Lens Lipids and Nuclear Light Scatter

TEMPOL protects against lens DNA strand breaks and cataract in the x-rayed rabbit.

The effect of aqueous humor ascorbate on ultraviolet-B-induced DNA damage in lens epithelium.

Role of small GTP-binding proteins in lovastatin-induced cataracts.

Effects of growth factors on proliferation and differentiation in human lens epithelial cells in early subculture.

Hypertonic stress increases NaK ATPase, taurine, and myoinositol in human lens and retinal pigment epithelial cultures.

The effect of hypertonicity on aldose reductase, alpha B-crystallin, and organic osmolytes in the retinal pigment epithelium.

Synthesis of lens capsule in long-term culture of human lens epithelial cells.

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